Acetylation regulates subcellular localization of eukaryotic translation initiation factor 5A (eIF5A)

FEBS Letters

Volumn 586, Issue 19, 2012, Pages 3236-3241

  Ishfaq, Muhammad ^a,b,c   Maeta, Kazuhiro ^a   Maeda, Satoko ^a   Natsume, Toru ^d   Ito, Akihiro ^a,e   Yoshida, Minoru ^a,b,e  

^a RIKEN   (Japan)

^b SAITAMA UNIVERSITY   (Japan)

^c KOHAT UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Pakistan)

^d NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Acetylation; eIF5A; Hypusination; Subcellular localization

Indexed keywords

HISTONE ACETYLTRANSFERASE PCAF; HISTONE DEACETYLASE 5; INITIATION FACTOR 5A; SIRTUIN 2;

ACETYLATION; ARTICLE; BIOACCUMULATION; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; ENZYME INHIBITION; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM;

ACETYLATION; ACTIVE TRANSPORT, CELL NUCLEUS; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HELA CELLS; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; LYSINE; P300-CBP TRANSCRIPTION FACTORS; PEPTIDE INITIATION FACTORS; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS; SIRTUIN 2; SUBCELLULAR FRACTIONS;

EUKARYOTA;

EID: 84866620575     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2012.06.042     Document Type: Article

References (28)

1. K.Y. Chen, and A.Y. Liu Biochemistry and function of hypusine formation on eukaryotic initiation factor 5A Biol. Signals 6 1997 105 109
2. M.H. Park, Y.B. Lee, and Y.A. Joe Hypusine is essential for eukaryotic cell proliferation Biol. Signals 6 1997 115 123
3. J. Schnier, H.G. Schwelberger, Z. Smit-McBride, H.A. Kang, and J.W. Hershey Translation initiation factor 5A and its hypusine modification are essential for cell viability in the yeast Saccharomyces cerevisiae Mol. Cell. Biol. 11 1991 3105 3114
4. H.L. Cooper, M.H. Park, J.E. Folk, B. Safer, and R. Braverman Identification of the hypusine-containing protein hy+ as translation initiation factor eIF-4D Proc. Natl. Acad. Sci. U S A 80 1983 1854 1857
5. M.H. Park The post-translational synthesis of a polyamine-derived amino acid, hypusine, in the eukaryotic translation initiation factor 5A (eIF5A) J. Biochem. 139 2006 161 169
6. M.H. Park, E.C. Wolff, and J.E. Folk Is hypusine essential for eukaryotic cell proliferation? Trends Biochem. Sci. 18 1993 475 479
7. M.H. Park, E.C. Wolff, Y.B. Lee, and J.E. Folk Antiproliferative effects of inhibitors of deoxyhypusine synthase. Inhibition of growth of Chinese hamster ovary cells by guanyl diamines J. Biol. Chem. 269 1994 27827 27832
8. H.M. Hanauske-Abel, M.H. Park, A.R. Hanauske, A.M. Popowicz, M. Lalande, and J.E. Folk Inhibition of the G1-S transition of the cell cycle by inhibitors of deoxyhypusine hydroxylation Biochim. Biophys. Acta 1221 1994 115 124
9. R. Benne, and J.W. Hershey The mechanism of action of protein synthesis initiation factors from rabbit reticulocytes J. Biol. Chem. 253 1978 3078 3087
10. M.H. Park The essential role of hypusine in eukaryotic translation initiation factor 4D (eIF-4D). Purification of eIF-4D and its precursors and comparison of their activities J. Biol. Chem. 264 1989 18531 18535
11. P. Saini, D.E. Eyler, R. Green, and T.E. Dever Hypusine-containing protein eIF5A promotes translation elongation Nature 459 2009 118 121
12. M. Ruhl Eukaryotic initiation factor-5a is a cellular target of the human-immunodeficiency-virus type-1 rev activation domain mediating transactivation J. Cell Biol. 123 1993 1309 1320
13. G. Lipowsky, F.R. Bischoff, P. Schwarzmaier, R. Kraft, S. Kostka, E. Hartmann, U. Kutay, and D. Gorlich Exportin 4: a mediator of a novel nuclear export pathway in higher eukaryotes EMBO J. 19 2000 4362 4371
14. X.J. Yang, V.V. Ogryzko, J. Nishikawa, B.H. Howard, and Y. Nakatani A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A Nature 382 1996 319 324
15. O. Rosorius, B. Reichart, F. Kratzer, P. Heger, M.C. Dabauvalle, and J. Hauber Nuclear pore localization and nucleocytoplasmic transport of eIF-5A: evidence for direct interaction with the export receptor CRM1 J. Cell Sci. 112 Pt 14 1999 2369 2380
16. E.S.L.T. Parreiras, M.D. Gomes, E.B. Oliveira, and C.M. Costa-Neto The N-terminal region of eukaryotic translation initiation factor 5A signals to nuclear localization of the protein Biochem. Biophys. Res. Commun. 362 2007 393 398
17. A.L. Li A novel eIF5A complex functions as a regulator of p53 and p53-dependent apoptosis J. Biol. Chem. 279 2004 49251 49258
18. B. Maier The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice J. Clin. Invest. 120 2010 2156 2170
19. S.B. Lee, J.H. Park, J. Kaevel, M. Sramkova, R. Weigert, and M.H. Park The effect of hypusine modification on the intracellular localization of eIF5A Biochem. Biophys. Res. Commun. 383 2009 497 502
20. M.H. Park The identification of an eukaryotic initiation factor 4D precursor in spermidine-depleted Chinese hamster ovary cells J. Biol. Chem. 263 1988 7447 7449
21. H. Klier, R. Csonga, H.C. Joao, C. Eckerskorn, M. Auer, F. Lottspeich, and J. Eder Isolation and structural characterization of different isoforms of the hypusine-containing protein eIF-5A from HeLa cells Biochemistry 34 1995 14693 14702
22. Y.F. Tong, I. Park, B.S. Hong, L. Nedyalkova, W. Tempel, and H.W. Park Crystal structure of human eIF5A1: Insight into functional similarity of human eIF5A1 and eIF5A2 Proteins 75 2009 1040 1045
23. C.A. Dias Structural modeling and mutational analysis of yeast eukaryotic translation initiation factor 5A reveal new critical residues and reinforce its involvement in protein synthesis FEBS J. 275 2008 1874 1888
24. I. Fukuda Ginkgolic acid inhibits protein SUMOylation by blocking formation of the E1-SUMO intermediate Chem. Biol. 16 2009 133 140
25. N. Nishino, B. Jose, S. Okamura, S. Ebisusaki, T. Kato, Y. Sumida, and M. Yoshida Cyclic tetrapeptides bearing a sulfhydryl group potently inhibit histone deacetylases Org. Lett. 5 2003 5079 5082
26. X.P. Shi, K.C. Yin, Z.A. Zimolo, A.M. Stern, and L. Waxman The subcellular distribution of eukaryotic translation initiation factor, eIF-5A, in cultured cells Exp. Cell Res. 225 1996 348 356
27. D.L. Jao, and K. Yu Chen Subcellular localization of the hypusine-containing eukaryotic initiation factor 5A by immunofluorescent staining and green fluorescent protein tagging J. Cell. Biochem. 86 2002 590 600
28. L. Zender An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer J. Cell Biol. 135 2008 852 864