Aberrant regulation of the LIN28A/LIN28B and let-7 loop in human malignant tumors and its effects on the hallmarks of cancer

Molecular Cancer

Volumn 14, Issue 1, 2015, Pages

  Wang, Tianzhen ^a   Wang, Guangyu ^a   Hao, Dapeng ^b   Liu, Xi ^c   Wang, Dong ^a   Ning, Ning ^d   Li, Xiaobo ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b University of Macau   (Macao)

^c Inner Mongolia Autonomous Region   (China)

^d PEKING UNIVERSITY INTERNATIONAL HOSPITAL   (China)

Author keywords

Hallmarks of cancer; LIN28A LIN28B and let 7 loop; MicroRNAs; RNA binding proteins

Indexed keywords

DICER; FAS ANTIGEN; MICRORNA; MICRORNA LET 7; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN LIN28A; PROTEIN LIN28B; RNA BINDING PROTEIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; UVOMORULIN; LIN28B PROTEIN, HUMAN; MIRNLET7 MICRORNA, HUMAN;

3' UNTRANSLATED REGION; AKT GENE; ANGIOGENESIS; BETA CATENIN GENE; BINDING AFFINITY; CELL CYCLE REGULATION; CELL METABOLISM; CELL PROLIFERATION; ENERGY METABOLISM; EPIGENETICS; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION; GENETIC TRANSFORMATION; GLYCOLYSIS; HUMAN; NEGATIVE FEEDBACK; NEOPLASM; NF KAPPAB GENE; NUCLEAR REPROGRAMMING; ONCOGENE; ONCOGENE MYC; ONCOGENE RAS; PI3K GENE; POSITIVE FEEDBACK; PROMOTER REGION; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; REVIEW; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ANIMAL; CELL TRANSFORMATION; GENE REGULATORY NETWORK; GENETICS; GENOMIC INSTABILITY; METABOLISM; PATHOLOGY; RNA INTERFERENCE;

ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; ENERGY METABOLISM; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE REGULATORY NETWORKS; GENOMIC INSTABILITY; HUMANS; MICRORNAS; NEOPLASMS; RNA INTERFERENCE; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION;

EID: 84937715111     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/s12943-015-0402-5     Document Type: Review

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