SOX2-LIN28/let-7 pathway regulates proliferation and neurogenesis in neural precursors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 32, 2013, Pages

  Cimadamore, Flavio ^a   Amador Arjona, Alejandro ^a   Chen, Connie ^a   Huang, Chun Teng ^a   Terskikh, Alexey V ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

Mechanisms of pluripotency; Neural stem cells

Indexed keywords

DNA METHYLTRANSFERASE 1; HISTONE ACETYLTRANSFERASE; HISTONE H3; LET 7B PROTEIN; LET 7I PROTEIN; LIN28 PROTEIN; NEUROGENIN 1; RNA BINDING PROTEIN; TRANSCRIPTION FACTOR MASH1; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; WNT1 PROTEIN;

3' UNTRANSLATED REGION; ACETYLATION; ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; EMBRYONIC STEM CELL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; MULTIPOTENT STEM CELL; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; SUBVENTRICULAR ZONE; UPREGULATION;

MECHANISMS OF PLURIPOTENCY; NEURAL STEM CELLS;

ANIMALS; BASE SEQUENCE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEK293 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICE, KNOCKOUT; MICRORNAS; NEURAL STEM CELLS; NEUROGENESIS; NEURONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; SOXB1 TRANSCRIPTION FACTORS;

EID: 84881403268     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1220176110     Document Type: Article

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