Retraction: HMGA2 functions as a competing endogenous RNA to promote lung cancer progression (Nature (2014) 505 (212-217) DOI:10.1038/nature12785);HMGA2 functions as a competing endogenous RNA to promote lung cancer progression

Nature

Volumn 505, Issue 7482, 2014, Pages 212-217

  Kumar, Madhu S ^a   Armenteros Monterroso, Elena ^a   East, Philip ^a   Chakravorty, Probir ^a   Matthews, Nik ^a   Winslow, Monte M ^b   Downward, Julian ^a,c  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARGONAUTE 2 PROTEIN; COMPETING ENDOGENOUS RNA; MICRORNA; PROTEIN TGFBR3; RECEPTOR; RNA; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ALGORITHM; CANCER; DISEASE TRANSMISSION; GENE EXPRESSION; HISTOLOGY; PROTEIN; RODENT; TRANSFORMATION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CONTROLLED STUDY; GENE; GENE EXPRESSION; GENE FUNCTION; HIGH MOBILITY GROUP A2 GENE; LUNG NON SMALL CELL CANCER; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR INVASION;

EID: 84892374204     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature14551     Document Type: Erratum

References (34)

1. Ferlay, J. et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int. J. Cancer 127, 2893-2917 (2010).
2. Herbst, R. S., Heymach, J. V. & Lippman, S. M. Lung cancer. N. Engl. J. Med. 359, 1367-1380 (2008).
3. Di Cello, F. et al.HMGA2 participates in transformation in humanlung cancer. Mol. Cancer Res. 6, 743-750 (2008).
4. Meyer, B. et al.HMGA2 overexpression in non-small cell lung cancer. Mol. Carcinog. 46, 503-511 (2007).
5. Sarhadi, V. K. et al. Increased expression of high mobility group A proteins in lung cancer. J. Pathol. 209, 206-212 (2006).
6. Winslow, M. M. et al. Suppression of lung adenocarcinomaprogression by Nkx2-1. Nature 473, 101-104 (2011).
7. Ebert, M. S., Neilson, J. R. & Sharp, P. A. MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nature Methods 4, 721-726 (2007).
8. Karreth, F. A. et al. In vivo identification of tumor-suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma. Cell 147, 382-395 (2011).
9. Poliseno, L. et al. A coding-independent function of gene and pseudogenemRNAs regulates tumour biology. Nature 465, 1033-1038 (2010).
10. Salmena, L., Poliseno, L., Tay, Y., Kats, L. & Pandolfi, P. P. A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language? Cell 146, 353-358 (2011).
11. Tay, Y. et al. Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs. Cell 147, 344-357 (2011).
12. Wang, X. F. et al. Expression cloning and characterization of the TGF-b type III receptor. Cell 67, 797-805 (1991).
13. Mayr, C., Hemann, M. T. & Bartel, D. P. Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science 315, 1576-1579 (2007).
14. Friedman, R. C., Farh, K. K., Burge, C. B.&Bartel, D. P.MostmammalianmRNAsare conserved targets of microRNAs. Genome Res. 19, 92-105 (2009).
15. Johnson, S. M. et al. RAS is regulated by the let-7 microRNA family. Cell 120, 635-647 (2005).
16. Brants, J. R. et al. Differential regulation of the insulin-like growth factor II mRNAbinding protein genesby architectural transcriptionfactorHMGA2. FEBSLett.569, 277-283 (2004).
17. vanDongen,S.,Abreu-Goodger, C.&Enright, A. J.Detecting microRNAbinding and siRNA off-target effects from expression data. Nature Methods 5, 1023-1025 (2008).
18. Xie, J. et al. Long-term, efficient inhibition of microRNAfunction in mice using rAAV vectors. Nature Methods 9, 403-409 (2012).
19. Massagué, J. TGFb signalling in context. Nature Rev. Mol. Cell Biol. 13, 616-630 (2012).
20. Guo, H., Ingolia, N. T., Weissman, J. S. & Bartel, D. P. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 466, 835-840 (2010).
21. Oida, T. & Weiner, H. L. Depletion of TGF-b from fetal bovine serum. J. Immunol. Methods 362, 195-198 (2010).
22. Dennler, S. et al. Direct binding of Smad3 and Smad4 to critical TGF b-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J. 17, 3091-3100 (1998).
23. Thuault, S. et al. HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition. J. Biol. Chem. 283, 33437-33446 (2008).
24. Ravi, A. et al. Proliferation and tumorigenesis of a murine sarcoma cell line in the absence of DICER1. Cancer Cell 21, 848-855 (2012).
25. Inman, G. J. et al. SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7. Mol. Pharmacol. 62, 65-74 (2002).
26. Shedden, K. et al. Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study. Nature Med. 14, 822-827 (2008).
27. Park, S. M. et al. Let-7 prevents early cancer progression by suppressing expression of the embryonic gene HMGA2. Cell Cycle 6, 2585-2590 (2007).
28. Kaelin, W. G., Jr. Molecular biology. Use and abuse of RNAi to study mammalian gene function. Science 337, 421-422 (2012).
29. Kumar, M. S. et al. The GATA2 transcriptional network is requisite for RAS oncogene-driven non-small cell lung cancer. Cell 149, 642-655 (2012).
30. Doench, J. G., Petersen, C. P. & Sharp, P. A. siRNAs can function as miRNAs. Genes Dev. 17, 438-442 (2003).
31. Liau, S. S., Jazag, A., Ito, K. & Whang, E. E. Overexpression of HMGA1 promotes anoikis resistance and constitutive Akt activation in pancreatic adenocarcinoma cells. Br. J. Cancer 96, 993-1000 (2007).
32. Kim, D. et al. TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol. 14, R36 (2013).
33. Robinson, M. D., McCarthy, D. J. & Smyth, G. K. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics 26, 139-140 (2010).
34. Trapnell, C. et al. Differential analysis of gene regulation at transcript resolution with RNA-seq. Nature Biotechnol. 31, 46-53 (2013).