Cellular stress induced alterations in microrna let-7a and let-7b expression are dependent on p53

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Saleh, Anthony D ^a   Savage, Jason E ^a   Cao, Liu ^b   Soule, Benjamin P ^c   Ly, David ^a   DeGraff, William ^a   Harris, Curtis C ^a   Mitchell, James B ^a   Simone, Nicole L ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; LUCIFERASE; MICRORNA; MICRORNA LET 7A; MICRORNA LET 7B; PROTEIN P53; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; MIRNLET7 MICRORNA, HUMAN; MIRNLET7 MICRORNA, MOUSE; PROTEIN BAX; PROTEIN SERINE THREONINE KINASE; PUMA PROTEIN, MOUSE; TUMOR SUPPRESSOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BINDING SITE; CELL STRAIN HCT116; CELL STRESS; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG TARGETING; FIBROBLAST; GENE; GENE EXPRESSION; GENE LOCATION; GENETIC REGULATION; GENOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; IONIZING RADIATION; KNOCKOUT MOUSE; LET7A GENE; LET7B GENE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RADIATION EXPOSURE; RADIOSENSITIVITY; RNA ANALYSIS; SIGNAL TRANSDUCTION; TRANSIENT TRANSFECTION; ANIMAL; C57BL MOUSE; DNA DAMAGE; ENHANCER REGION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PHOSPHORYLATION; ULTRAVIOLET RADIATION;

MUS;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; CELL CYCLE PROTEINS; DNA DAMAGE; DNA-BINDING PROTEINS; ENHANCER ELEMENTS, GENETIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HCT116 CELLS; HUMANS; MICE; MICE, INBRED C57BL; MICRORNAS; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; ULTRAVIOLET RAYS;

EID: 80054115192     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024429     Document Type: Article

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