-
1
-
-
40449120350
-
An oncogene-induced DNA damage model for cancer development
-
Halazonetis T.D., Gorgoulis V.G., Bartek J. An oncogene-induced DNA damage model for cancer development. Science 2008, 319:1352-1355.
-
(2008)
Science
, vol.319
, pp. 1352-1355
-
-
Halazonetis, T.D.1
Gorgoulis, V.G.2
Bartek, J.3
-
2
-
-
70350504453
-
The DNA-damage response in human biology and disease
-
Jackson S.P., Bartek J. The DNA-damage response in human biology and disease. Nature 2009, 461:1071-1078.
-
(2009)
Nature
, vol.461
, pp. 1071-1078
-
-
Jackson, S.P.1
Bartek, J.2
-
4
-
-
84859171807
-
MYC on the path to cancer
-
Dang C.V. MYC on the path to cancer. Cell 2012, 149:22-35.
-
(2012)
Cell
, vol.149
, pp. 22-35
-
-
Dang, C.V.1
-
5
-
-
22144453538
-
C-Myc induces chromosomal rearrangements through telomere and chromosome remodeling in the interphase nucleus
-
Louis S.F., Vermolen B.J., Garini Y., Young I.T., Guffei A., Lichtensztejn Z., Kuttler F., Chuang T.C., Moshir S., Mougey V., Chuang A.Y., Kerr P.D., Fest T., Boukamp P., Mai S. c-Myc induces chromosomal rearrangements through telomere and chromosome remodeling in the interphase nucleus. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:9613-9618.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 9613-9618
-
-
Louis, S.F.1
Vermolen, B.J.2
Garini, Y.3
Young, I.T.4
Guffei, A.5
Lichtensztejn, Z.6
Kuttler, F.7
Chuang, T.C.8
Moshir, S.9
Mougey, V.10
Chuang, A.Y.11
Kerr, P.D.12
Fest, T.13
Boukamp, P.14
Mai, S.15
-
6
-
-
56849093474
-
Distinct thresholds govern Myc's biological output in vivo
-
Murphy D.J., Junttila M.R., Pouyet L., Karnezis A., Shchors K., Bui D.A., Brown-Swigart L., Johnson L., Evan G.I. Distinct thresholds govern Myc's biological output in vivo. Cancer Cell 2008, 14:447-457.
-
(2008)
Cancer Cell
, vol.14
, pp. 447-457
-
-
Murphy, D.J.1
Junttila, M.R.2
Pouyet, L.3
Karnezis, A.4
Shchors, K.5
Bui, D.A.6
Brown-Swigart, L.7
Johnson, L.8
Evan, G.I.9
-
7
-
-
0043193855
-
Defective double-strand DNA break repair and chromosomal translocations by MYC overexpression
-
Karlsson A., Deb-Basu D., Cherry A., Turner S., Ford J., Felsher D.W. Defective double-strand DNA break repair and chromosomal translocations by MYC overexpression. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:9974-9979.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 9974-9979
-
-
Karlsson, A.1
Deb-Basu, D.2
Cherry, A.3
Turner, S.4
Ford, J.5
Felsher, D.W.6
-
8
-
-
33746106937
-
MYC can induce DNA breaks in vivo and in vitro independent of reactive oxygen species
-
Ray S., Atkuri K.R., Deb-Basu D., Adler A.S., Chang H.Y., Herzenberg L.A., Felsher D.W. MYC can induce DNA breaks in vivo and in vitro independent of reactive oxygen species. Cancer Res. 2006, 66:6598-6605.
-
(2006)
Cancer Res.
, vol.66
, pp. 6598-6605
-
-
Ray, S.1
Atkuri, K.R.2
Deb-Basu, D.3
Adler, A.S.4
Chang, H.Y.5
Herzenberg, L.A.6
Felsher, D.W.7
-
9
-
-
0036285034
-
C-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability
-
Vafa O., Wade M., Kern S., Beeche M., Pandita T.K., Hampton G.M., Wahl G.M. c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability. Mol. Cell 2002, 9:1031-1044.
-
(2002)
Mol. Cell
, vol.9
, pp. 1031-1044
-
-
Vafa, O.1
Wade, M.2
Kern, S.3
Beeche, M.4
Pandita, T.K.5
Hampton, G.M.6
Wahl, G.M.7
-
10
-
-
67649439003
-
Facilitating replication under stress: an oncogenic function of MYC?
-
Herold S., Herkert B., Eilers M. Facilitating replication under stress: an oncogenic function of MYC?. Nat. Rev. Cancer 2009, 9:441-444.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 441-444
-
-
Herold, S.1
Herkert, B.2
Eilers, M.3
-
11
-
-
84902116617
-
DNA double-strand break repair pathway choice and cancer
-
Aparicio T., Baer R., Gautier J. DNA double-strand break repair pathway choice and cancer. DNA Repair 2014, 19:169-175.
-
(2014)
DNA Repair
, vol.19
, pp. 169-175
-
-
Aparicio, T.1
Baer, R.2
Gautier, J.3
-
12
-
-
84899035081
-
Myc induced replicative stress response: how to cope with it and exploit it
-
Rohban S., Campaner S. Myc induced replicative stress response: how to cope with it and exploit it. Biochim. Biophys. Acta 2014, 10.1016/j.bbagrm.2014.04.008.
-
(2014)
Biochim. Biophys. Acta
-
-
Rohban, S.1
Campaner, S.2
-
13
-
-
0028237305
-
Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells
-
Rouet P., Smih F., Jasin M. Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells. Proc. Natl. Acad. Sci. U. S. A. 1994, 91:6064-6068.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 6064-6068
-
-
Rouet, P.1
Smih, F.2
Jasin, M.3
-
14
-
-
0042626553
-
Recruitment of the recombinational repair machinery to a DNA double-strand break in yeast
-
Wolner B., van Komen S., Sung P., Peterson C.L. Recruitment of the recombinational repair machinery to a DNA double-strand break in yeast. Mol. Cell 2003, 12:221-232.
-
(2003)
Mol. Cell
, vol.12
, pp. 221-232
-
-
Wolner, B.1
van Komen, S.2
Sung, P.3
Peterson, C.L.4
-
15
-
-
77953720192
-
ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks
-
Shanbhag N.M., Rafalska-Metcalf I.U., Balane-Bolivar C., Janicki S.M., Greenberg R.A. ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks. Cell 2010, 141:970-981.
-
(2010)
Cell
, vol.141
, pp. 970-981
-
-
Shanbhag, N.M.1
Rafalska-Metcalf, I.U.2
Balane-Bolivar, C.3
Janicki, S.M.4
Greenberg, R.A.5
-
16
-
-
77951498531
-
High-resolution profiling of gammaH2AX around DNA double strand breaks in the mammalian genome
-
Iacovoni J.S., Caron P., Lassadi I., Nicolas E., Massip L., Trouche D., Legube G. High-resolution profiling of gammaH2AX around DNA double strand breaks in the mammalian genome. EMBO J. 2010, 29:1446-1457.
-
(2010)
EMBO J.
, vol.29
, pp. 1446-1457
-
-
Iacovoni, J.S.1
Caron, P.2
Lassadi, I.3
Nicolas, E.4
Massip, L.5
Trouche, D.6
Legube, G.7
-
17
-
-
77956803702
-
Deciphering the chromatin landscape induced around DNA double strand breaks
-
Massip L., Caron P., Iacovoni J.S., Trouche D., Legube G. Deciphering the chromatin landscape induced around DNA double strand breaks. Cell cycle 2010, 9:2963-2972.
-
(2010)
Cell cycle
, vol.9
, pp. 2963-2972
-
-
Massip, L.1
Caron, P.2
Iacovoni, J.S.3
Trouche, D.4
Legube, G.5
-
18
-
-
84857498961
-
Cohesin protects genes against gammaH2AX induced by DNA double-strand breaks
-
Caron P., Aymard F., Iacovoni J.S., Briois S., Canitrot Y., Bugler B., Massip L., Losada A., Legube G. Cohesin protects genes against gammaH2AX induced by DNA double-strand breaks. PLoS Genet. 2012, 8:e1002460.
-
(2012)
PLoS Genet.
, vol.8
, pp. e1002460
-
-
Caron, P.1
Aymard, F.2
Iacovoni, J.S.3
Briois, S.4
Canitrot, Y.5
Bugler, B.6
Massip, L.7
Losada, A.8
Legube, G.9
-
19
-
-
84897990643
-
Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks
-
Aymard F., Bugler B., Schmidt C.K., Guillou E., Caron P., Briois S., Iacovoni J.S., Daburon V., Miller K.M., Jackson S.P., Legube G. Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks. Nat. Struct. Mol. Biol. 2014, 21:366-374.
-
(2014)
Nat. Struct. Mol. Biol.
, vol.21
, pp. 366-374
-
-
Aymard, F.1
Bugler, B.2
Schmidt, C.K.3
Guillou, E.4
Caron, P.5
Briois, S.6
Iacovoni, J.S.7
Daburon, V.8
Miller, K.M.9
Jackson, S.P.10
Legube, G.11
-
20
-
-
77954053278
-
LSD1-mediated demethylation of histone H3 lysine 4 triggers Myc-induced transcription
-
Amente S., Bertoni A., Morano A., Lania L., Avvedimento E.V., Majello B. LSD1-mediated demethylation of histone H3 lysine 4 triggers Myc-induced transcription. Oncogene 2010, 29:3691-3702.
-
(2010)
Oncogene
, vol.29
, pp. 3691-3702
-
-
Amente, S.1
Bertoni, A.2
Morano, A.3
Lania, L.4
Avvedimento, E.V.5
Majello, B.6
-
21
-
-
33750295885
-
Transfection of mammalian cells using linear polyethylenimine is a simple and effective means of producing recombinant adeno-associated virus vectors
-
Reed S.E., Staley E.M., Mayginnes J.P., Pintel D.J., Tullis G.E. Transfection of mammalian cells using linear polyethylenimine is a simple and effective means of producing recombinant adeno-associated virus vectors. J. Virol. Methods 2006, 138:85-98.
-
(2006)
J. Virol. Methods
, vol.138
, pp. 85-98
-
-
Reed, S.E.1
Staley, E.M.2
Mayginnes, J.P.3
Pintel, D.J.4
Tullis, G.E.5
-
22
-
-
84884595018
-
Sequence-specific double strand breaks trigger P-TEFb-dependent Rpb1-CTD hyperphosphorylation
-
Napolitano G., Amente S., Lavadera M.L., Di Palo G., Ambrosio S., Lania L., Dellino G.I., Pelicci P.G., Majello B. Sequence-specific double strand breaks trigger P-TEFb-dependent Rpb1-CTD hyperphosphorylation. Mutat. Res. 2013, 749:21-27.
-
(2013)
Mutat. Res.
, vol.749
, pp. 21-27
-
-
Napolitano, G.1
Amente, S.2
Lavadera, M.L.3
Di Palo, G.4
Ambrosio, S.5
Lania, L.6
Dellino, G.I.7
Pelicci, P.G.8
Majello, B.9
-
23
-
-
0348149148
-
Repair of a minimal DNA double-strand break by NHEJ requires DNA-PKcs and is controlled by the ATM/ATR checkpoint
-
Kuhne C., Tjornhammar M.L., Pongor S., Banks L., Simoncsits A. Repair of a minimal DNA double-strand break by NHEJ requires DNA-PKcs and is controlled by the ATM/ATR checkpoint. Nucleic Acids Res. 2003, 31:7227-7237.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 7227-7237
-
-
Kuhne, C.1
Tjornhammar, M.L.2
Pongor, S.3
Banks, L.4
Simoncsits, A.5
-
24
-
-
34249947699
-
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
-
Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R., Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N., Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science 2007, 316:1160-1166.
-
(2007)
Science
, vol.316
, pp. 1160-1166
-
-
Matsuoka, S.1
Ballif, B.A.2
Smogorzewska, A.3
McDonald, E.R.4
Hurov, K.E.5
Luo, J.6
Bakalarski, C.E.7
Zhao, Z.8
Solimini, N.9
Lerenthal, Y.10
Shiloh, Y.11
Gygi, S.P.12
Elledge, S.J.13
-
25
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou E.P., Pilch D.R., Orr A.H., Ivanova V.S., Bonner W.M. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem. 1998, 273:5858-5868.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
26
-
-
0029743372
-
Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells
-
Lutz W., Stohr M., Schurmann J., Wenzel A., Lohr A., Schwab A. Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells. Oncogene 1996, 13:803-812.
-
(1996)
Oncogene
, vol.13
, pp. 803-812
-
-
Lutz, W.1
Stohr, M.2
Schurmann, J.3
Wenzel, A.4
Lohr, A.5
Schwab, A.6
-
27
-
-
84871602994
-
C-Myc suppression of DNA double-strand break repair
-
Li Z., Owonikoko T.K., Sun S.Y., Ramalingam S.S., Doetsch P.W., Xiao Z.Q., Khuri F.R., Curran W.J., Deng X. c-Myc suppression of DNA double-strand break repair. Neoplasia 2012, 14:1190-1202.
-
(2012)
Neoplasia
, vol.14
, pp. 1190-1202
-
-
Li, Z.1
Owonikoko, T.K.2
Sun, S.Y.3
Ramalingam, S.S.4
Doetsch, P.W.5
Xiao, Z.Q.6
Khuri, F.R.7
Curran, W.J.8
Deng, X.9
-
28
-
-
84899926214
-
Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo
-
Phesse T.J., Myant K.B., Cole A.M., Ridgway R.A., Pearson H., Muncan V., van den Brink G.R., Vousden K.H., Sears R., Vassilev L.T., Clarke A.R., Sansom O.J. Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo. Cell Death Differ. 2014, 21:956-966.
-
(2014)
Cell Death Differ.
, vol.21
, pp. 956-966
-
-
Phesse, T.J.1
Myant, K.B.2
Cole, A.M.3
Ridgway, R.A.4
Pearson, H.5
Muncan, V.6
van den Brink, G.R.7
Vousden, K.H.8
Sears, R.9
Vassilev, L.T.10
Clarke, A.R.11
Sansom, O.J.12
-
29
-
-
0033569423
-
INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53
-
Schmitt C.A., McCurrach M.E., de Stanchina E., Wallace-Brodeur R.R., Lowe S.W. INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53. Genes Dev. 1999, 13:2670-2677.
-
(1999)
Genes Dev.
, vol.13
, pp. 2670-2677
-
-
Schmitt, C.A.1
McCurrach, M.E.2
de Stanchina, E.3
Wallace-Brodeur, R.R.4
Lowe, S.W.5
-
30
-
-
78650336901
-
Proteomic profiling of Myc-associated proteins
-
Agrawal P., Yu K., Salomon A.R., Sedivy J.M. Proteomic profiling of Myc-associated proteins. Cell Cycle 2010, 9:4908-4921.
-
(2010)
Cell Cycle
, vol.9
, pp. 4908-4921
-
-
Agrawal, P.1
Yu, K.2
Salomon, A.R.3
Sedivy, J.M.4
-
31
-
-
33846929680
-
Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach
-
Koch H.B., Zhang R., Verdoodt B., Bailey A., Zhang C.D., Yates J.R., Menssen A., Hermeking H. Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach. Cell Cycle 2007, 6:205-217.
-
(2007)
Cell Cycle
, vol.6
, pp. 205-217
-
-
Koch, H.B.1
Zhang, R.2
Verdoodt, B.3
Bailey, A.4
Zhang, C.D.5
Yates, J.R.6
Menssen, A.7
Hermeking, H.8
-
32
-
-
84885390492
-
Chromatin structure in double strand break repair
-
Gospodinov A., Herceg Z. Chromatin structure in double strand break repair. DNA Repair 2013, 12:800-810.
-
(2013)
DNA Repair
, vol.12
, pp. 800-810
-
-
Gospodinov, A.1
Herceg, Z.2
-
33
-
-
84872649417
-
Shaping chromatin for repair
-
Gospodinov A., Herceg Z. Shaping chromatin for repair. Mutat. Res. 2013, 752:45-60.
-
(2013)
Mutat. Res.
, vol.752
, pp. 45-60
-
-
Gospodinov, A.1
Herceg, Z.2
-
34
-
-
84859371639
-
Histone marks: repairing DNA breaks within the context of chromatin
-
Miller K.M., Jackson S.P. Histone marks: repairing DNA breaks within the context of chromatin. Biochem. Soc. Trans. 2012, 40:370-376.
-
(2012)
Biochem. Soc. Trans.
, vol.40
, pp. 370-376
-
-
Miller, K.M.1
Jackson, S.P.2
-
35
-
-
84863001577
-
Prime, repair, restore: the active role of chromatin in the DNA damage response
-
Soria G., Polo S.E., Almouzni G. Prime, repair, restore: the active role of chromatin in the DNA damage response. Mol. Cell 2012, 46:722-734.
-
(2012)
Mol. Cell
, vol.46
, pp. 722-734
-
-
Soria, G.1
Polo, S.E.2
Almouzni, G.3
-
36
-
-
84904906418
-
Role of polycomb group proteins in the DNA damage response - a reassessment
-
Chandler H., Patel H., Palermo R., Brookes S., Matthews N., Peters G. Role of polycomb group proteins in the DNA damage response - a reassessment. PLOS ONE 2014, 9:e102968.
-
(2014)
PLOS ONE
, vol.9
, pp. e102968
-
-
Chandler, H.1
Patel, H.2
Palermo, R.3
Brookes, S.4
Matthews, N.5
Peters, G.6
-
37
-
-
84904823447
-
Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles
-
Walz S., Lorenzin F., Morton J., Wiese K.E., von Eyss B., Herold S., Rycak L., Dumay-Odelot H., Karim S., Bartkuhn M., Roels F., Wustefeld T., Fischer M., Teichmann M., Zender L., Wei C.L., Sansom O., Wolf E., Eilers M. Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles. Nature 2014, 511:483-487.
-
(2014)
Nature
, vol.511
, pp. 483-487
-
-
Walz, S.1
Lorenzin, F.2
Morton, J.3
Wiese, K.E.4
von Eyss, B.5
Herold, S.6
Rycak, L.7
Dumay-Odelot, H.8
Karim, S.9
Bartkuhn, M.10
Roels, F.11
Wustefeld, T.12
Fischer, M.13
Teichmann, M.14
Zender, L.15
Wei, C.L.16
Sansom, O.17
Wolf, E.18
Eilers, M.19
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