Lin28 promotes growth of prostate cancer cells and activates the androgen receptor

American Journal of Pathology

Volumn 183, Issue 1, 2013, Pages 288-295

  Tummala, Ramakumar ^a   Nadiminty, Nagalakshmi ^a,c   Lou, Wei ^a   Zhu, Yezi ^a   Gandour Edwards, Regina ^a,c   Chen, Hong Wu ^b,c   Evans, Christopher P ^a,c   Gao, Allen C ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; RNA BINDING PROTEIN; RNA BINDING PROTEIN LIN28; UNCLASSIFIED DRUG;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CARCINOGENESIS; CELL GROWTH; CELL INVASION; CLONOGENESIS; COLONY FORMATION; CONTROLLED STUDY; DOWN REGULATION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL LINE, TUMOR; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, NUDE; PROSTATIC NEOPLASMS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, ANDROGEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA-BINDING PROTEINS; TUMOR MARKERS, BIOLOGICAL;

EID: 84879355935     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2013.03.011     Document Type: Article

References (40)

1. N. Nadiminty, and A.C. Gao Mechanisms of persistent activation of the androgen receptor in CRPC: recent advances and future perspectives World J Urol 30 2012 287 295
2. E.G. Moss, and L. Tang Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites Dev Biol 258 2003 432 442
3. J. Takamizawa, H. Konishi, K. Yanagisawa, S. Tomida, H. Osada, H. Endoh, T. Harano, Y. Yatabe, M. Nagino, Y. Nimura, T. Mitsudomi, and T. Takahashi Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival Cancer Res 64 2004 3753 3756
4. S. Shell, S.M. Park, A.R. Radjabi, R. Schickel, E.O. Kistner, D.A. Jewell, C. Feig, E. Lengyel, and M.E. Peter Let-7 expression defines two differentiation stages of cancer Proc Natl Acad Sci U S A 104 2007 11400 11405
5. Y. Akao, Y. Nakagawa, and T. Naoe let-7 microRNA functions as a potential growth suppressor in human colon cancer cells Biol Pharm Bull 29 2006 903 906
6. N. Nadiminty, R. Tummala, W. Lou, Y. Zhu, J. Zhang, X. Chen, R.W. DeVere White, H.-J. Kung, C.P. Evans, and A.C. Gao MicroRNA let-7c suppresses androgen receptor expression and activity via regulation of Myc expression in prostate cancer cells J Biol Chem 287 2012 1527 1537
7. N. Nadiminty, R. Tummala, W. Lou, Y. Zhu, X.-B. Shi, J.X. Zou, H. Chen, J. Zhang, X. Chen, J. Luo, R.W. DeVere White, H.-J. Kung, C.P. Evans, and A.C. Gao MicroRNA let-7c is downregulated in prostate cancer and suppresses prostate cancer growth PLoS One 7 2012 e32832
8. S.R. Viswanathan, J.T. Powers, W. Einhorn, Y. Hoshida, T.L. Ng, S. Toffanin, M. O'Sullivan, J. Lu, L.A. Phillips, V.L. Lockhart, S.P. Shah, P.S. Tanwar, C.H. Mermel, R. Beroukhim, M. Azam, J. Teixeira, M. Meyerson, T.P. Hughes, J.M. Llovet, J. Radich, C.G. Mullighan, T.R. Golub, P.H. Sorensen, and G.Q. Daley Lin28 promotes transformation and is associated with advanced human malignancies Nat Genet 41 2009 843 848
9. D. Iliopoulos, H. Hirsch, and K. Struhl An epigenetic switch involving NF-kappaB, Lin28, Let-7 microRNA and IL6 links inflammation to cell transformation Cell 139 2009 693 706
10. S. Peng, N. Maihle, and Y. Huang Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer Oncogene 29 2010 2153 2159
11. S.R. Viswanathan, G.Q. Daley, and R.I. Gregory Selective blockade of microRNA processing by Lin28 Science 320 2008 97 100
12. S.R. Viswanathan, and G.Q. Daley Lin28: a microRNA regulator with a macro role Cell 140 2010 445 449
13. T.-C. Chang, L.R. Zeitels, H.-W. Hwang, R.R. Chivukula, E.A. Wentzel, M. Dews, J. Jung, P. Gao, C.V. Dang, M.A. Beer, A. Thomas-Tikhonenko, and J.T. Mendell Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation Proc Natl Acad Sci U S A 106 2009 3384 3389
14. S. Dangi-Garimella, J. Yun, E.M. Eves, M. Newman, S.J. Erkeland, S.M. Hammond, A.J. Minn, and M.R. Rosner Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7 EMBO J 28 2009 347 358
15. J. Lu, G. Getz, E.A. Miska, E. Alvarez-Saavedra, J. Lamb, D. Peck, A. Sweet-Cordero, B.L. Ebert, R.H. Mak, A.A. Ferrando, J.R. Downing, T. Jacks, H.R. Horvitz, and T.R. Golub MicroRNA expression profiles classify human cancers Nature 435 2005 834 838
16. J.Y. Chun, N. Nadiminty, S. Dutt, W. Lou, J.C. Yang, H.-J. Kung, C.P. Evans, and A.C. Gao Interleukin-6 regulates androgen synthesis in prostate cancer cells Clin Cancer Res 15 2009 4815 4822
17. N. Nadiminty, W. Lou, M. Sun, J. Chen, J. Yue, H.-J. Kung, C.P. Evans, Q. Zhou, and A.C. Gao Aberrant activation of the androgen receptor by NF-κB2/p52 in prostate cancer cells Cancer Res 70 2010 3309 3319
18. N. Nadiminty, J.Y. Chun, W. Lou, X. Lin, and A.C. Gao NF-κB2/p52 enhances androgen-independent growth of human LNCaP cells via protection from apoptotic cell death and cell cycle arrest induced by androgen-deprivation Prostate 68 2008 1725 1733
19. J.C. Yang, J.H. Ok, J.E. Busby, A.D. Borowsky, H.J. Kung, and C.P. Evans Aberrant activation of androgen receptor in a new neuropeptide-autocrine model of androgen-insensitive prostate cancer Cancer Res 69 2009 151 160
20. T.A. Dunn, S. Chen, D.A. Faith, J.L. Hicks, E.A. Platz, Y. Chen, C.M. Ewing, J. Sauvageot, W.B. Isaacs, A.M. De Marzo, and J. Luo A novel role of myosin VI in human prostate cancer Am J Pathol 169 2006 1843 1854
21. Z. Ni, W. Lou, S.O.K. Lee, R. Dhir, F. De Miguel, J.R. Grandis, and A.C. Gao Selective activation of members of the signal transducers and activators of transcription family in prostate carcinoma J Urol 167 2002 1859 1862
22. R. Dhir, Z. Ni, W. Lou, F. DeMiguel, J.R. Grandis, and A.C. Gao Stat3 activation in prostatic carcinomas Prostate 51 2002 241 246
23. R. Hamano, H. Miyata, M. Yamasaki, K. Sugimura, K. Tanaka, Y. Kurokawa, K. Nakajima, S. Takiguchi, Y. Fujiwara, M. Mori, and Y. Doki High expression of Lin28 is associated with tumour aggressiveness and poor prognosis of patients in oesophagus cancer Br J Cancer 106 2012 1415 1423
24. Ã. Helland, M.S. Anglesio, J. George, P.A. Cowin, C.N. Johnstone, C.M. House, K.E. Sheppard, D. Etemadmoghadam, N. Melnyk, A.K. Rustgi, W.A. Phillips, H. Johnsen, R. Holm, G.B. Kristensen, M.J. Birrer, R.B. Pearson, A.L. Børresen-Dale, D.G. Huntsman, A. deFazio, C.J. Creighton, G.K. Smyth, D.D. Bowtell Australian Ovarian Cancer Study Group Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers PLoS One 6 2011 e18064
25. C.E. King, M. Cuatrecasas, A. Castells, A.R. Sepulveda, J.-S. Lee, and A.K. Rustgi LIN28B promotes colon cancer progression and metastasis Cancer Res 71 2011 4260 4268
26. C.E. King, L. Wang, R. Winograd, B.B. Madison, P.S. Mongroo, C.N. Johnstone, and A.K. Rustgi LIN28B fosters colon cancer migration, invasion and transformation through let-7-dependent and -independent mechanisms Oncogene 30 2011 4185 4193
27. I. Heo, C. Joo, Y.-K. Kim, M. Ha, M.-J. Yoon, J. Cho, K.-H. Yeom, J. Han, and V.N. Kim TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation Cell 138 2009 696 708
28. N.J. Lehrbach, and E.A. Miska Regulation of pre-miRNA processing Adv Exp Med Biol 700 2010 67 75
29. E.F. Vêncio, A.M. Nelson, C. Cavanaugh, C.B. Ware, D.G. Miller, J.C. Garcia, R.Z. Vêncio, M.A. Loprieno, and A.Y. Liu Reprogramming of prostate cancer-associated stromal cells to embryonic stem-like Prostate 72 2012 1453 1463
30. E.G. Moss, R.C. Lee, and V. Ambros The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA Cell 88 1997 637 646
31. E. Balzer, and E.G. Moss Localization of the developmental timing regulator Lin28 to mRNP complexes, P-bodies and stress granules RNA Biol 4 2007 16 25
32. D.-H. Yang, and E.G. Moss Temporally regulated expression of Lin-28 in diverse tissues of the developing mouse Gene Expression Patterns 3 2003 719 726
33. Y. Guo, Y. Chen, H. Ito, A. Watanabe, X. Ge, T. Kodama, and H. Aburatani Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma Gene 384 2006 51 61
34. N. Shyh-Chang, and G.Q. Daley Lin28: primal regulator of growth and metabolism in stem cells Cell Stem Cell 12 2013 395 406
35. L. Lu, D. Katsaros, K. Shaverdashvili, B. Qian, Y. Wu, I.A.R. de la Longrais, M. Preti, G. Menato, and H. Yu Pluripotent factor lin-28 and its homologue lin-28b in epithelial ovarian cancer and their associations with disease outcomes and expression of let-7a and IGF-II Eur J Cancer 45 2009 2212 2218
36. D. Iliopoulos, H.A. Hirsch, and K. Struhl An epigenetic switch involving NF-κB, Lin28, Let-7 microRNA, and IL6 links inflammation to cell transformation Cell 139 2009 693 706
37. N. Nadiminty, S. Dutt, C. Tepper, and A.C. Gao Microarray analysis reveals potential target genes of NF-κB2/p52 in LNCaP prostate cancer cells Prostate 70 2010 276 287
38. Y. Huang A mirror of two faces: Lin28 as a master regulator of both miRNA and mRNA Wiley Interdiscip Rev RNA 3 2012 483 494
39. X.X. Lei, J. Xu, W. Ma, C. Qiao, M.A. Newman, S.M. Hammond, and Y. Huang Determinants of mRNA recognition and translation regulation by Lin28 Nucleic Acids Res 40 2012 3574 3584
40. M.L. Wilbert, S.C. Huelga, K. Kapeli, T.J. Stark, T.Y. Liang, S.X. Chen, B.Y. Yan, J.L. Nathanson, K.R. Hutt, M.T. Lovci, H. Kazan, A.Q. Vu, K.B. Massirer, Q. Morris, S. Hoon, and G.W. Yeo LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance Mol Cell 48 2012 195 206