Balancing Proliferation and Connectivity in PTEN-associated Autism Spectrum Disorder

Neurotherapeutics

Volumn 12, Issue 3, 2015, Pages 609-619

  Tilot, Amanda K ^a,c   Frazier, Thomas W ^a   Eng, Charis ^a,b,c,d,e  

^a LERNER RESEARCH INSTITUTE   (United States)

^b TAUSSIG CANCER INSTITUTE   (United States)

^c CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE   (United States)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

genetics; mouse model; neuroimaging; PTEN hamartoma tumor syndrome; social behavior; syndromic

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; MTOR PROTEIN, HUMAN; PTEN PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

ANXIETY; AUTISM; COMPULSION; GENETIC ASSOCIATION; GENOTYPE; GERMLINE MUTATION; HAMARTOMA; HUMAN; LANGUAGE DELAY; LIFESPAN; MACROCEPHALY; MULTIPLE CANCER; NERVE CELL PLASTICITY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REVIEW; RISK ASSESSMENT; THYROID CANCER; WHITE MATTER; WORKING MEMORY; ANIMAL; ANTAGONISTS AND INHIBITORS; AUTISM SPECTRUM DISORDER; BRAIN; CELL PROLIFERATION; DISEASE MODEL; FEMALE; GENETICS; MALE; METABOLISM; MOUSE; MUTATION; NERVE CELL; SIGNAL TRANSDUCTION;

ANIMALS; AUTISM SPECTRUM DISORDER; BRAIN; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; FEMALE; GENOTYPE; HUMANS; MALE; MICE; MUTATION; NEURONS; PHENOTYPE; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84937642552     PISSN: 19337213     EISSN: 18787479     Source Type: Journal    
DOI: 10.1007/s13311-015-0356-8     Document Type: Review

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