A clinical scoring system for selection of patients for pten mutation testing is proposed on the basis of a prospective study of 3042 probands

American Journal of Human Genetics

Volumn 88, Issue 1, 2011, Pages 42-56

  Tan, Min Han ^a   Mester, Jessica ^a   Peterson, Charissa ^a   Yang, Yiran ^a   Chen, Jin Lian ^a   Rybicki, Lisa A ^a,b   Milas, Kresimira ^a   Pederson, Holly ^a   Remzi, Berna ^a   Orloff, Mohammed S ^a,b   Eng, Charis ^a,b,c  

^a LERNER RESEARCH INSTITUTE   (United States)

^b TAUSSIG CANCER INSTITUTE   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CLEVELAND CLINIC SCORE; CLINICAL PRACTICE; CONTROLLED STUDY; COWDEN SYNDROME; FEMALE; GENE DELETION; GENE MUTATION; GENOTYPE; GERM LINE; HUMAN; IMMUNOBLOTTING; MAJOR CLINICAL STUDY; MALE; NATIONAL COMPREHENSIVE CANCER NETWORK CRITERIA; NUCLEOTIDE SEQUENCE; PATIENT SELECTION; PHENOTYPE; PREDICTIVE VALUE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROMOTER REGION; PROSPECTIVE STUDY; PROTEIN EXPRESSION; SCHOOL CHILD; SCORING SYSTEM;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHILD; COHORT STUDIES; FEMALE; GENETIC TESTING; GERM-LINE MUTATION; HAMARTOMA SYNDROME, MULTIPLE; HUMANS; MALE; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, GENETIC; PATIENT SELECTION; PROMOTER REGIONS, GENETIC; PROSPECTIVE STUDIES; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; YOUNG ADULT;

EID: 78650908302     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2010.11.013     Document Type: Article

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