Genetic disruption of Pten in a novel mouse model of tomaculous neuropathy

EMBO Molecular Medicine

Volumn 4, Issue 6, 2012, Pages 486-499

  Goebbels, Sandra ^a   Oltrogge, Jan H ^a   Wolfer, Susanne ^a   Wieser, Georg L ^a   Nientiedt, Tobias ^a   Pieper, Alexander ^a   Ruhwedel, Torben ^a   Groszer, Matthias ^b   Sereda, Michael W ^a,c   Nave, Klaus Armin ^a  

^a MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^b INSTITUT DU FER À MOULIN   (France)

^c UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Myelin outfolding; Neuropathy; Rapamycin; Schwann cells; Tomacula

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; MYELIN; PERIPHERAL MYELIN PROTEIN 22; PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; RAPAMYCIN; TAMOXIFEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE DISRUPTION; HAPLOINSUFFICIENCY; HEREDITARY MOTOR SENSORY NEUROPATHY; MOUSE; MYELINATION; NERVE FIBER GROWTH; NEUROPATHY; NONHUMAN; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; PROTEIN FOLDING; SCHWANN CELL; SIGNAL TRANSDUCTION; TOMACULOUS NEUROPATHY;

ANIMALS; ARTHROGRYPOSIS; CELL LINE; DISEASE MODELS, ANIMAL; GENE KNOCKOUT TECHNIQUES; HEREDITARY SENSORY AND MOTOR NEUROPATHY; MICE; MYELIN SHEATH; PTEN PHOSPHOHYDROLASE; SCHWANN CELLS;

EID: 84861917238     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201200227     Document Type: Article

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