A short N-terminal sequence of PTEN controls cytoplasmic localization and is required for suppression of cell growth

Oncogene

Volumn 26, Issue 27, 2007, Pages 3930-3940

  Denning, G ^a,b   Jean Joseph, B ^b   Prince, C ^b   Durden, D L ^b   Vogt, P K ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cytoplasmic localization signal; Lipid binding; Mutation; PTEN; Tumor suppressor

Indexed keywords

PHOSPHATASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CANCER INHIBITION; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; EMBRYO; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MUTATION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID SEQUENCE; BINDING SITES; CELL LINE; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; CYTOPLASM; GERM-LINE MUTATION; GREEN FLUORESCENT PROTEINS; HUMANS; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PHOSPHATIDYLINOSITOL PHOSPHATES; PROTEIN SORTING SIGNALS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 34249991191     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210175     Document Type: Article

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