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Volumn 522, Issue 5, 2014, Pages 1171-1190

PTEN knockdown alters dendritic spine/protrusion morphology, not density

(13)  Haws, Michael E a,b   Jaramillo, Thomas C a   Espinosa, Felipe a   Widman, Allie a   Stuber, Garret D f,h   Sparta, Dennis R f   Tye, Kay M f,i   Russo, Scott J c   Parada, Luis F b   Stavarache, Mihaela d   Kaplitt, Michael d   Bonci, Antonello e,g   Powell, Craig M a,b  


Author keywords

AKT; Amygdale; Dendrite; Dentate gyrus; MTOR; PTEN; Spine

Indexed keywords

AKT; AMYGDALE; DENDRITE; DENTATE GYRUS; MTOR; PTEN; SPINE;

EID: 84893732333     PISSN: 00219967     EISSN: 10969861     Source Type: Journal    
DOI: 10.1002/cne.23488     Document Type: Article
Times cited : (45)

References (73)
  • 2
    • 54049127490 scopus 로고    scopus 로고
    • Ultrastructure of dendritic spines: correlation between synaptic and spine morphologies
    • Arellano JI, Benavides-Piccione R, Defelipe J, Yuste R. 2007. Ultrastructure of dendritic spines: correlation between synaptic and spine morphologies. Front Neurosci 1:131-143.
    • (2007) Front Neurosci , vol.1 , pp. 131-143
    • Arellano, J.I.1    Benavides-Piccione, R.2    Defelipe, J.3    Yuste, R.4
  • 4
    • 0032550793 scopus 로고    scopus 로고
    • Selective and rapid uptake of adeno-associated virus type 2 in brain
    • Bartlett JS, Samulski RJ, McCown TJ. 1998. Selective and rapid uptake of adeno-associated virus type 2 in brain. Hum Gene Ther 9:1181-1186.
    • (1998) Hum Gene Ther , vol.9 , pp. 1181-1186
    • Bartlett, J.S.1    Samulski, R.J.2    McCown, T.J.3
  • 5
    • 0000227612 scopus 로고    scopus 로고
    • PTEN/MMAC1/TEP1 in signal transduction and tumorigenesis
    • Besson A, Robbins SM, Yong VW. 1999. PTEN/MMAC1/TEP1 in signal transduction and tumorigenesis. Eur J Biochem 263:605-611.
    • (1999) Eur J Biochem , vol.263 , pp. 605-611
    • Besson, A.1    Robbins, S.M.2    Yong, V.W.3
  • 7
    • 77950970508 scopus 로고    scopus 로고
    • RIM1alpha and interacting proteins involved in presynaptic plasticity mediate prepulse inhibition and additional behaviors linked to schizophrenia
    • Blundell J, Kaeser PS, Sudhof TC, Powell CM. 2010. RIM1alpha and interacting proteins involved in presynaptic plasticity mediate prepulse inhibition and additional behaviors linked to schizophrenia. J Neurosci 30:5326-5333.
    • (2010) J Neurosci , vol.30 , pp. 5326-5333
    • Blundell, J.1    Kaeser, P.S.2    Sudhof, T.C.3    Powell, C.M.4
  • 9
    • 34249933982 scopus 로고    scopus 로고
    • Do thin spines learn to be mushroom spines that remember?
    • Bourne J, Harris KM. 2007. Do thin spines learn to be mushroom spines that remember? Curr Opin Neurobiol 17:381-386.
    • (2007) Curr Opin Neurobiol , vol.17 , pp. 381-386
    • Bourne, J.1    Harris, K.M.2
  • 12
    • 0033856110 scopus 로고    scopus 로고
    • PTEN, a unique tumor suppressor gene
    • Dahia PL. 2000. PTEN, a unique tumor suppressor gene. Endocr Relat Cancer 7:115-129.
    • (2000) Endocr Relat Cancer , vol.7 , pp. 115-129
    • Dahia, P.L.1
  • 13
    • 0028270269 scopus 로고
    • Neurotransmission in the rat amygdala related to fear and anxiety
    • Davis M, Rainnie D, Cassell M. 1994. Neurotransmission in the rat amygdala related to fear and anxiety. Trends Neurosci 17:208-214.
    • (1994) Trends Neurosci , vol.17 , pp. 208-214
    • Davis, M.1    Rainnie, D.2    Cassell, M.3
  • 14
    • 0034681264 scopus 로고    scopus 로고
    • The multiple roles of PTEN in tumor suppression
    • Di Cristofano A, Pandolfi PP. 2000. The multiple roles of PTEN in tumor suppression. Cell 100:387-390.
    • (2000) Cell , vol.100 , pp. 387-390
    • Di Cristofano, A.1    Pandolfi, P.P.2
  • 15
    • 0030919664 scopus 로고    scopus 로고
    • Heterogeneity of release probability, facilitation, and depletion at central synapses
    • Dobrunz LE, Stevens CF. 1997. Heterogeneity of release probability, facilitation, and depletion at central synapses. Neuron 18:995-1008.
    • (1997) Neuron , vol.18 , pp. 995-1008
    • Dobrunz, L.E.1    Stevens, C.F.2
  • 17
    • 77953189368 scopus 로고    scopus 로고
    • Selective changes in thin spine density and morphology in monkey prefrontal cortex correlate with aging-related cognitive impairment
    • Dumitriu D, Hao J, Hara Y, Kaufmann J, Janssen WG, Lou W, Rapp PR, Morrison JH. 2010. Selective changes in thin spine density and morphology in monkey prefrontal cortex correlate with aging-related cognitive impairment. J Neurosci 30:7507-7515.
    • (2010) J Neurosci , vol.30 , pp. 7507-7515
    • Dumitriu, D.1    Hao, J.2    Hara, Y.3    Kaufmann, J.4    Janssen, W.G.5    Lou, W.6    Rapp, P.R.7    Morrison, J.H.8
  • 18
    • 80052410549 scopus 로고    scopus 로고
    • High-throughput, detailed, cell-specific neuroanatomy of dendritic spines using microinjection and confocal microscopy
    • Dumitriu D, Rodriguez A, Morrison JH. 2011. High-throughput, detailed, cell-specific neuroanatomy of dendritic spines using microinjection and confocal microscopy. Nat Protoc 6:1391-1411.
    • (2011) Nat Protoc , vol.6 , pp. 1391-1411
    • Dumitriu, D.1    Rodriguez, A.2    Morrison, J.H.3
  • 20
    • 84861113384 scopus 로고    scopus 로고
    • Subregional, dendritic compartment, and spine subtype specificity in cocaine regulation of dendritic spines in the nucleus accumbens
    • Dumitriu D, Laplant Q, Grossman YS, Dias C, Janssen WG, Russo SJ, Morrison JH, Nestler EJ. 2012b. Subregional, dendritic compartment, and spine subtype specificity in cocaine regulation of dendritic spines in the nucleus accumbens. J Neurosci 32:6957-6966.
    • (2012) J Neurosci , vol.32 , pp. 6957-6966
    • Dumitriu, D.1    Laplant, Q.2    Grossman, Y.S.3    Dias, C.4    Janssen, W.G.5    Russo, S.J.6    Morrison, J.H.7    Nestler, E.J.8
  • 22
    • 0033374970 scopus 로고    scopus 로고
    • The role of PTEN, a phosphatase gene, in inherited and sporadic nonmedullary thyroid tumors
    • discussion 453
    • Eng C. 1999. The role of PTEN, a phosphatase gene, in inherited and sporadic nonmedullary thyroid tumors. Recent Prog Horm Res 54:441-452; discussion 453.
    • (1999) Recent Prog Horm Res , vol.54 , pp. 441-452
    • Eng, C.1
  • 23
    • 0042316755 scopus 로고    scopus 로고
    • PTEN: one gene, many syndromes
    • Eng C. 2003. PTEN: one gene, many syndromes. Hum Mutat 22:183-198.
    • (2003) Hum Mutat , vol.22 , pp. 183-198
    • Eng, C.1
  • 24
    • 0036206066 scopus 로고    scopus 로고
    • Dendritic spines do not split during hippocampal LTP or maturation
    • Fiala JC, Allwardt B, Harris KM. 2002. Dendritic spines do not split during hippocampal LTP or maturation. Nat Neurosci 5:297-298.
    • (2002) Nat Neurosci , vol.5 , pp. 297-298
    • Fiala, J.C.1    Allwardt, B.2    Harris, K.M.3
  • 26
    • 37849027524 scopus 로고    scopus 로고
    • Phosphatase and tensin homolog, deleted on chromosome 10 deficiency in brain causes defects in synaptic structure, transmission and plasticity, and myelination abnormalities
    • Fraser MM, Bayazitov IT, Zakharenko SS, Baker SJ. 2008. Phosphatase and tensin homolog, deleted on chromosome 10 deficiency in brain causes defects in synaptic structure, transmission and plasticity, and myelination abnormalities. Neuroscience 151:476-488.
    • (2008) Neuroscience , vol.151 , pp. 476-488
    • Fraser, M.M.1    Bayazitov, I.T.2    Zakharenko, S.S.3    Baker, S.J.4
  • 30
    • 0024473444 scopus 로고
    • Dendritic spines of CA 1 pyramidal cells in the rat hippocampus: serial electron microscopy with reference to their biophysical characteristics
    • Harris KM, Stevens JK. 1989. Dendritic spines of CA 1 pyramidal cells in the rat hippocampus: serial electron microscopy with reference to their biophysical characteristics. J Neurosci 9:2982-2997.
    • (1989) J Neurosci , vol.9 , pp. 2982-2997
    • Harris, K.M.1    Stevens, J.K.2
  • 31
    • 33847342035 scopus 로고    scopus 로고
    • Increasing knowledge of PTEN germline mutations: two additional patients with autism and macrocephaly
    • Herman GE, Butter E, Enrile B, Pastore M, Prior TW, Sommer A. 2007. Increasing knowledge of PTEN germline mutations: two additional patients with autism and macrocephaly. Am J Med Genet 143:589-593.
    • (2007) Am J Med Genet , vol.143 , pp. 589-593
    • Herman, G.E.1    Butter, E.2    Enrile, B.3    Pastore, M.4    Prior, T.W.5    Sommer, A.6
  • 32
    • 70350238781 scopus 로고    scopus 로고
    • PTEN hamartoma tumor syndrome: an overview
    • Hobert JA, Eng C. 2009. PTEN hamartoma tumor syndrome: an overview. Genet Med 11:687-694.
    • (2009) Genet Med , vol.11 , pp. 687-694
    • Hobert, J.A.1    Eng, C.2
  • 33
    • 75749114797 scopus 로고    scopus 로고
    • mTOR signaling: at the crossroads of plasticity, memory and disease
    • Hoeffer CA, Klann E. 2010. mTOR signaling: at the crossroads of plasticity, memory and disease. Trends Neurosci 33:67-75.
    • (2010) Trends Neurosci , vol.33 , pp. 67-75
    • Hoeffer, C.A.1    Klann, E.2
  • 36
    • 0242268407 scopus 로고    scopus 로고
    • mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo
    • Kwon CH, Zhu X, Zhang J, Baker SJ. 2003. mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo. Proc Natl Acad Sci U S A 100:12923-12928.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 12923-12928
    • Kwon, C.H.1    Zhu, X.2    Zhang, J.3    Baker, S.J.4
  • 38
    • 84855862362 scopus 로고    scopus 로고
    • Stress leads to contrasting effects on the levels of brain derived neurotrophic factor in the hippocampus and amygdala
    • Lakshminarasimhan H, Chattarji S. 2012. Stress leads to contrasting effects on the levels of brain derived neurotrophic factor in the hippocampus and amygdala. PloS One 7:e30481.
    • (2012) PloS One , vol.7
    • Lakshminarasimhan, H.1    Chattarji, S.2
  • 39
    • 35348858152 scopus 로고    scopus 로고
    • The amygdala
    • LeDoux J. 2007. The amygdala. Curr Biol 17:R868-874.
    • (2007) Curr Biol , vol.17
    • LeDoux, J.1
  • 40
    • 0036181869 scopus 로고    scopus 로고
    • PTEN: The down side of PI 3-kinase signalling
    • Leslie NR, Downes CP. 2002. PTEN: The down side of PI 3-kinase signalling. Cell Signal 14:285-295.
    • (2002) Cell Signal , vol.14 , pp. 285-295
    • Leslie, N.R.1    Downes, C.P.2
  • 43
    • 0032577699 scopus 로고    scopus 로고
    • The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
    • Maehama T, Dixon JE. 1998. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3, 4, 5-trisphosphate. J Biol Chem 273:13375-13378.
    • (1998) J Biol Chem , vol.273 , pp. 13375-13378
    • Maehama, T.1    Dixon, J.E.2
  • 44
    • 0032904432 scopus 로고    scopus 로고
    • PTEN: a tumour suppressor that functions as a phospholipid phosphatase
    • Maehama T, Dixon JE. 1999. PTEN: a tumour suppressor that functions as a phospholipid phosphatase. Trends Cell Biol 9:125-128.
    • (1999) Trends Cell Biol , vol.9 , pp. 125-128
    • Maehama, T.1    Dixon, J.E.2
  • 45
    • 39749159041 scopus 로고    scopus 로고
    • Spine-type-specific recruitment of newly synthesized AMPA receptors with learning
    • Matsuo N, Reijmers L, Mayford M. 2008. Spine-type-specific recruitment of newly synthesized AMPA receptors with learning. Science 319:1104-1107.
    • (2008) Science , vol.319 , pp. 1104-1107
    • Matsuo, N.1    Reijmers, L.2    Mayford, M.3
  • 46
    • 77955626857 scopus 로고    scopus 로고
    • Confirmation study of PTEN mutations among individuals with autism or developmental delays/mental retardation and macrocephaly
    • McBride KL, Varga EA, Pastore MT, Prior TW, Manickam K, Atkin JF, Herman GE. 2010. Confirmation study of PTEN mutations among individuals with autism or developmental delays/mental retardation and macrocephaly. Autism Res 3:137-141.
    • (2010) Autism Res , vol.3 , pp. 137-141
    • McBride, K.L.1    Varga, E.A.2    Pastore, M.T.3    Prior, T.W.4    Manickam, K.5    Atkin, J.F.6    Herman, G.E.7
  • 47
    • 0020416188 scopus 로고
    • Neurons of the lateral and basolateral amygdaloid nuclei: a Golgi study in the rat
    • McDonald AJ. 1982. Neurons of the lateral and basolateral amygdaloid nuclei: a Golgi study in the rat. J Comp Neurol 212:293-312.
    • (1982) J Comp Neurol , vol.212 , pp. 293-312
    • McDonald, A.J.1
  • 51
    • 0026697724 scopus 로고
    • NeuN, a neuronal specific nuclear protein in vertebrates
    • Mullen RJ, Buck CR, Smith AM. 1992. NeuN, a neuronal specific nuclear protein in vertebrates. Development 116:201-211.
    • (1992) Development , vol.116 , pp. 201-211
    • Mullen, R.J.1    Buck, C.R.2    Smith, A.M.3
  • 53
    • 0032167980 scopus 로고    scopus 로고
    • Cell type and pathway dependence of synaptic AMPA receptor number and variability in the hippocampus
    • Nusser Z, Lujan R, Laube G, Roberts JD, Molnar E, Somogyi P. 1998. Cell type and pathway dependence of synaptic AMPA receptor number and variability in the hippocampus. Neuron 21:545-559.
    • (1998) Neuron , vol.21 , pp. 545-559
    • Nusser, Z.1    Lujan, R.2    Laube, G.3    Roberts, J.D.4    Molnar, E.5    Somogyi, P.6
  • 54
    • 51849143274 scopus 로고    scopus 로고
    • Genetic and phenotypic heterogeneity in the PTEN hamartoma tumour syndrome
    • Orloff MS, Eng C. 2008. Genetic and phenotypic heterogeneity in the PTEN hamartoma tumour syndrome. Oncogene 27:5387-5397.
    • (2008) Oncogene , vol.27 , pp. 5387-5397
    • Orloff, M.S.1    Eng, C.2
  • 59
    • 34248652917 scopus 로고    scopus 로고
    • Rayburst sampling, an algorithm for automated three-dimensional shape analysis from laser scanning microscopy images
    • Rodriguez A, Ehlenberger DB, Hof PR, Wearne SL. 2006. Rayburst sampling, an algorithm for automated three-dimensional shape analysis from laser scanning microscopy images. Nat Protoc 1:2152-2161.
    • (2006) Nat Protoc , vol.1 , pp. 2152-2161
    • Rodriguez, A.1    Ehlenberger, D.B.2    Hof, P.R.3    Wearne, S.L.4
  • 60
    • 44349154735 scopus 로고    scopus 로고
    • Automated three-dimensional detection and shape classification of dendritic spines from fluorescence microscopy images
    • Rodriguez A, Ehlenberger DB, Dickstein DL, Hof PR, Wearne SL. 2008. Automated three-dimensional detection and shape classification of dendritic spines from fluorescence microscopy images. PloS One 3:e1997.
    • (2008) PloS One , vol.3
    • Rodriguez, A.1    Ehlenberger, D.B.2    Dickstein, D.L.3    Hof, P.R.4    Wearne, S.L.5
  • 66
    • 62149104335 scopus 로고    scopus 로고
    • The prevalence of PTEN mutations in a clinical pediatric cohort with autism spectrum disorders, developmental delay, and macrocephaly
    • Varga EA, Pastore M, Prior T, Herman GE, McBride KL. 2009. The prevalence of PTEN mutations in a clinical pediatric cohort with autism spectrum disorders, developmental delay, and macrocephaly. Genet Med 11:111-117.
    • (2009) Genet Med , vol.11 , pp. 111-117
    • Varga, E.A.1    Pastore, M.2    Prior, T.3    Herman, G.E.4    McBride, K.L.5
  • 67
    • 0033957661 scopus 로고    scopus 로고
    • The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling
    • Vazquez F, Sellers WR. 2000. The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling. Biochim Biophys Acta 1470:M21-35.
    • (2000) Biochim Biophys Acta , vol.1470
    • Vazquez, F.1    Sellers, W.R.2
  • 68
    • 0036206130 scopus 로고    scopus 로고
    • Protean PTEN: form and function
    • Waite KA, Eng C. 2002. Protean PTEN: form and function. Am J Hum Genet 70:829-844.
    • (2002) Am J Hum Genet , vol.70 , pp. 829-844
    • Waite, K.A.1    Eng, C.2
  • 69
    • 28844498390 scopus 로고    scopus 로고
    • New techniques for imaging, digitization and analysis of three-dimensional neural morphology on multiple scales
    • Wearne SL, Rodriguez A, Ehlenberger DB, Rocher AB, Henderson SC, Hof PR. 2005. New techniques for imaging, digitization and analysis of three-dimensional neural morphology on multiple scales. Neuroscience 136:661-680.
    • (2005) Neuroscience , vol.136 , pp. 661-680
    • Wearne, S.L.1    Rodriguez, A.2    Ehlenberger, D.B.3    Rocher, A.B.4    Henderson, S.C.5    Hof, P.R.6
  • 70
    • 84856668811 scopus 로고    scopus 로고
    • PTEN Regulation of local and long-range connections in mouse auditory cortex
    • Xiong Q, Oviedo HV, Trotman LC, Zador AM. 2012. PTEN Regulation of local and long-range connections in mouse auditory cortex. J Neurosci 32:1643-1652.
    • (2012) J Neurosci , vol.32 , pp. 1643-1652
    • Xiong, Q.1    Oviedo, H.V.2    Trotman, L.C.3    Zador, A.M.4
  • 72
    • 60849109211 scopus 로고    scopus 로고
    • Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice
    • Zhou J, Blundell J, Ogawa S, Kwon CH, Zhang W, Sinton C, Powell CM, Parada LF. 2009. Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice. J Neurosci 29:1773-1783.
    • (2009) J Neurosci , vol.29 , pp. 1773-1783
    • Zhou, J.1    Blundell, J.2    Ogawa, S.3    Kwon, C.H.4    Zhang, W.5    Sinton, C.6    Powell, C.M.7    Parada, L.F.8
  • 73
    • 0031741226 scopus 로고    scopus 로고
    • Germline PTEN mutation in a family with Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome
    • Zori RT, Marsh DJ, Graham GE, Marliss EB, Eng C. 1998. Germline PTEN mutation in a family with Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome. Am J Med Genet 80:399-402.
    • (1998) Am J Med Genet , vol.80 , pp. 399-402
    • Zori, R.T.1    Marsh, D.J.2    Graham, G.E.3    Marliss, E.B.4    Eng, C.5


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