Should patients with Cowden syndrome undergo prophylactic thyroidectomy?

Surgery (United States)

Volumn 152, Issue 6, 2012, Pages 1201-1210

  Milas, Mira ^a   Mester, Jessica ^b,c   Metzger, Rosemarie ^b   Shin, Joyce ^b   Mitchell, Jamie ^b   Berber, Eren ^b   Siperstein, Allan E ^b   Eng, Charis ^b,c,d  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c TAUSSIG CANCER INSTITUTE   (United States)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANAPLASTIC THYROID CANCER; ARTICLE; AUTISM; COWDEN SYNDROME; DISEASE SEVERITY; ECHOGRAPHY; FEMALE; GENE; GENE MUTATION; GOITER; HUMAN; INTRAOPERATIVE PERIOD; MAJOR CLINICAL STUDY; MALE; NEEDLE BIOPSY; PATIENT MONITORING; PRIORITY JOURNAL; PROSPECTIVE STUDY; PTEN GENE; SEDATION; THYROID FOLLICULAR CARCINOMA; THYROID NODULE; THYROID PAPILLARY CARCINOMA; THYROIDECTOMY; THYROIDITIS;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; FEMALE; GERM-LINE MUTATION; HAMARTOMA SYNDROME, MULTIPLE; HUMANS; MALE; MIDDLE AGED; PTEN PHOSPHOHYDROLASE; THYROID NEOPLASMS; THYROIDECTOMY; YOUNG ADULT;

EID: 84869457014     PISSN: 00396060     EISSN: 15327361     Source Type: Journal    
DOI: 10.1016/j.surg.2012.08.055     Document Type: Article

References (21)

1. C. Eng Will the real Cowden syndrome please stand up: revised diagnostic criteria J Med Genet 37 2000 828 830
2. M.H. Tan, J.L. Mester, J. Ngeow, L.A. Rybicki, M.S. Orloff, and C. Eng Lifetime cancer risks in individuals with germline PTEN mutations Clin Cancer Res 18 2012 400 407
3. J. Ngeow, J. Mester, L.A. Rybicki, Y. Ni, M. Milas, and C. Eng Incidence and clinical characteristics of thyroid cancer in prospective series of individuals with Cowden and Cowden-like syndrome characterized by germline PTEN, SDH, or KLLN alterations J Clin Endocrinol Metab 96 2011 E2063 E2071
4. M.R. Nelen, G.W. Padberg, E.A. Peeters, A.Y. Lin, B. van den Helm, and R.R. Frants Localization of the gene for Cowden disease to chromosome 10q22-23 Nat Genet 13 1996 114 116
5. D. Liaw, D.J. Marsh, J. Li, P.L. Dahia, S.I. Wang, and Z. Zheng Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome Nat Genet 16 1997 64 67
6. D.J. Marsh, V. Coulon, K.L. Lunetta, P. Rocca-Serra, P.L. Dahia, and Z. Zheng Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation Hum Mol Genet 7 1998 507 515
7. M.H. Tan, J. Mester, C. Peterson, Y. Yang, J.L. Chen, and L.A. Rybicki A clinical scoring system for selection of patients for PTEN mutation testing is proposed on the basis of a prospective study of 3042 probands Am J Hum Genet 88 2011 42 56
8. J.A. Hobart, and C. Eng PTEN hamartoma tumor syndrome: an overview Genet Med 11 2009 687 694
9. S. Gustafson, K.M. Zbuk, C. Scacheri, and C. Eng Cowden syndrome Semin Oncol 34 2007 428 434
10. R. Pilarski, and C. Eng Will the real Cowden syndrome please stand up (again)? Expanding mutational and clinical spectra of the PTEN hamartoma tumour syndrome J Med Genet 41 2004 323 326
11. Surveillance Epidemiology and End Results (SEER) cancer statistics. Available from http://seer.cancer.gov/.
12. T. Novosel, H.E. Ritter, M. Gupta, A. Harvey, J. Mitchell, and E. Berber Detection of circulating thyroid cancer cells in patients with thyroid microcarcinomas Surgery 146 2009 1081 1089
13. PTEN risk calculator website. Available from http://www.lerner.ccf.org/ gmi/ccscore/.
14. D.S. Cooper, G.M. Doherty, and B.R. Haugen Revised American Thyroid Association Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer Thyroid 19 2009 1167 1214
15. R.M. Tuttle, D.W. Ball, D. Byrd, R.A. Dilawari, G.M. Doherty, Q.Y. Duh National Comprehensive Cancer Network Thyroid carcinoma J Natl Compr Canc Netw 8 2010 1228 1274
16. Y. Ni, K.M. Zbuk, and T. Sadler Germline mutations and variants in the succinate dehydrogenase genes n Cowden and Cowden-like syndromes Am J Hum Genet 83 2008 261 268
17. Y. Ni, X. He, and J. Chen Germline SDHx variants modify breast and thyroid cancer risks in Cowden and Cowden-like syndrome via FAD/NAD-dependent destabilization of p53 Hum Mol Genet 21 2012 300 310
18. K.L. Bennett, J. Mester, and C. Eng Germline epigenetic regulation of KILLIN in Cowden and Cowden-like syndrome JAMA 304 2010 2724 2731
19. R. Nagy, S. Ganapathi, and I. Comeras Frequency of germline PTEN mutations in differentiated thyroid cancer Thyroid 21 2011 505 510
20. D.E. Goldgar, D.F. Easton, L.A. Cannon-Albright, and M.H. Skolnick Systematic population-based assessment of cancer risk in first-degree relatives of cancer probands J Natl Cancer Inst 86 1994 1600 1608
21. M.R. Nelen, H. Kremer, and I.B. Konings Novel PTEN mutations in patients with Cowden disease: Absence of clear genotype-phenotype correlations Eur J Hum Genet 7 1999 267 273