Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 12, 2013, Pages 4738-4743

  Takeuchi, Koichi ^a,c   Gertner, Michael J ^a   Zhou, Jing ^b,d   Parada, Luis F ^b   Bennett, Michael V L ^a   Zukin, R Suzanne ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

^c UNIVERSITY OF TOKYO   (Japan)

^d DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METABOTROPIC RECEPTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTISM; COGNITION; CONTROLLED STUDY; DENTATE GYRUS; ENZYME INACTIVATION; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA3 REGION; KNOCKOUT MOUSE; LONG TERM DEPRESSION; LONG TERM POTENTIATION; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; SOCIAL BEHAVIOR; SYNAPTIC TRANSMISSION;

AGING; ANIMALS; AUTISTIC DISORDER; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; HUMANS; LONG-TERM POTENTIATION; MICE; MICE, KNOCKOUT; MUTATION; NERVE TISSUE PROTEINS; PHOSPHATIDYLINOSITOL 3-KINASES; PTEN PHOSPHOHYDROLASE; RECEPTORS, METABOTROPIC GLUTAMATE; SIGNAL TRANSDUCTION; SYNAPSES;

EID: 84875270373     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1222803110     Document Type: Article

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