Germline disruption of Pten localization causes enhanced sex-dependent social motivation and increased glial production

Human Molecular Genetics

Volumn 23, Issue 12, 2014, Pages 3212-3227

  Tilot, Amanda K ^a,b   Gaugler, Mary K ^b   Yu, Qi ^b   Romigh, Todd ^b   Yu, Wanfeng ^b   Miller, Robert H ^d   Frazier II, Thomas W ^a,b   Eng, Charis ^a,b,c,d  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c TAUSSIG CANCER INSTITUTE   (United States)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOPLASM PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PTEN PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; ASTROCYTOSIS; AUTISM; AUTOSOMAL DOMINANT DISORDER; BRAIN DEVELOPMENT; BRAIN GROWTH; BRAIN REGION; CANCER CELL LINE; CELL PROLIFERATION; CELL SIZE; CELLULAR DISTRIBUTION; FEMALE; GERMLINE MUTATION; GOLGI STAIN; HIPPOCAMPUS; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MACROCEPHALY; MALE; MICROGLIA; MISSENSE MUTATION; MOTIVATION; MOUSE; NERVOUS SYSTEM INFLAMMATION; NISSL STAINING; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; OLIGODENDROGLIA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PTEN HAMARTOMA TUMOR SYNDROME; PYRAMIDAL NERVE CELL; RECOGNITION; SOCIAL BEHAVIOR; WESTERN BLOTTING; ANIMAL; BRAIN; CELL NUCLEUS; CYTOPLASM; DISEASE MODEL; GENE TARGETING; GENETICS; GLIA; METABOLISM; PATHOPHYSIOLOGY; SEXUAL DEVELOPMENT; SIGNAL TRANSDUCTION;

ANIMALS; BRAIN; CELL NUCLEUS; CELL PROLIFERATION; CHILD DEVELOPMENT DISORDERS, PERVASIVE; CYTOPLASM; DISEASE MODELS, ANIMAL; FEMALE; GENE KNOCK-IN TECHNIQUES; HUMANS; MALE; MICE; MUTATION, MISSENSE; NEUROGLIA; PTEN PHOSPHOHYDROLASE; SEX CHARACTERISTICS; SIGNAL TRANSDUCTION; SOCIAL BEHAVIOR;

EID: 84901362837     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu031     Document Type: Article

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