Distinct single-cell signaling characteristics are conferred by the MyD88 and TRIF pathways during TLR4 activation

Science Signaling

Volumn 8, Issue 385, 2015, Pages

  Cheng, Zhang ^a,b   Taylor, Brooks ^a,b   Ourthiague, Diana R ^b   Hoffmann, Alexander ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b University of California San Diego   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TRANSCRIPTION FACTOR RELA; LIGAND; MYD88 PROTEIN, MOUSE; NFKB1 PROTEIN, MOUSE; TICAM-1 PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL MATURATION; CELL MEMBRANE; CELL POPULATION; CELL SELECTION; CELL SURFACE; CELL TRACKING; CONTROLLED STUDY; CYTOMETRY; ENDOCYTOSIS; ENDOSOME; GENE EXPRESSION; IN VITRO STUDY; INTERNALIZATION; LIGAND BINDING; MACROPHAGE; MATHEMATICAL MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; QUANTITATIVE STUDY; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ALGORITHM; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL LINE; FEMUR; INNATE IMMUNITY; METABOLISM; PATHOLOGY; PHYSIOLOGY; THEORETICAL MODEL;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ALGORITHMS; ANIMALS; CELL LINE; CELL MEMBRANE; CELLS, CULTURED; FEMUR; IMMUNITY, INNATE; LIGANDS; MACROPHAGES; MICE; MICE, INBRED C57BL; MODELS, THEORETICAL; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B P50 SUBUNIT; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84937576990     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.aaa5208     Document Type: Article

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