-
1
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NFκB by Toll-like receptor 3
-
Alexopoulou L., Holt AC, Medzhitov R, Flavell RA. 2001. Recognition of double-stranded RNA and activation of NFκB by Toll-like receptor 3. Nature 413: 732-738.
-
(2001)
Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
2
-
-
33750269857
-
Transmembrane TNF protects mutant mice against intracellular bacterial infections, chronic inflammation and autoimmunity
-
Alexopoulou L., Kranidioti K, Xanthoulea S, Denis M, Kotanidou A, Douni E, Blackshear PJ, Kontoyiannis DL, Kollias G. 2006. Transmembrane TNF protects mutant mice against intracellular bacterial infections, chronic inflammation and autoimmunity. Eur J Immunol 36: 2768-2780.
-
(2006)
Eur J Immunol
, vol.36
, pp. 2768-2780
-
-
Alexopoulou, L.1
Kranidioti, K.2
Xanthoulea, S.3
Denis, M.4
Kotanidou, A.5
Douni, E.6
Blackshear, P.J.7
Kontoyiannis, D.L.8
Kollias, G.9
-
3
-
-
84902552747
-
HTSeq—a Python framework to work with high-throughput sequencing data
-
Anders S., Pyl PT, Huber W. 2014. HTSeq—a Python framework to work with high-throughput sequencing data. bioRxiv doi: 10.1101/002824.
-
(2014)
bioRxiv
-
-
Anders, S.1
Pyl, P.T.2
Huber, W.3
-
4
-
-
32344445358
-
Posttranscriptional regulation of TNFα expression via eukaryotic initiation factor 4E (eIF4E) phosphorylation in mouse macrophages
-
Andersson K., Sundler R. 2006. Posttranscriptional regulation of TNFα expression via eukaryotic initiation factor 4E (eIF4E) phosphorylation in mouse macrophages. Cytokine 33: 52-57.
-
(2006)
Cytokine
, vol.33
, pp. 52-57
-
-
Andersson, K.1
Sundler, R.2
-
5
-
-
84858728161
-
Lessons from mathematically modeling the NF-κB pathway
-
Basak S., Behar M, Hoffmann A. 2012. Lessons from mathematically modeling the NF-κB pathway. Immunol Rev 246: 221- 238.
-
(2012)
Immunol Rev
, vol.246
, pp. 221-238
-
-
Basak, S.1
Behar, M.2
Hoffmann, A.3
-
6
-
-
8044257704
-
A metalloproteinase disintegrin that releases tumournecrosis factor-α from cells
-
Black R.A., Rauch CT, Kozlosky CJ, Peschon JJ, Slack JL, Wolfson MF, Castner BJ, Stocking KL, Reddy P, Srinivasan S, et al. 1997. A metalloproteinase disintegrin that releases tumournecrosis factor-α from cells. Nature 385: 729-733.
-
(1997)
Nature
, vol.385
, pp. 729-733
-
-
Black, R.A.1
Rauch, C.T.2
Kozlosky, C.J.3
Peschon, J.J.4
Slack, J.L.5
Wolfson, M.F.6
Castner, B.J.7
Stocking, K.L.8
Reddy, P.9
Srinivasan, S.10
-
7
-
-
0028273016
-
Tumor necrosis factor as an autocrine and paracrine signal controlling the macrophage secretory response to Candida albicans
-
Blasi E., Pitzurra L, Bartoli A, Puliti M, Bistoni F. 1994. Tumor necrosis factor as an autocrine and paracrine signal controlling the macrophage secretory response to Candida albicans. Infect Immun 62: 1199-1206.
-
(1994)
Infect Immun
, vol.62
, pp. 1199-1206
-
-
Blasi, E.1
Pitzurra, L.2
Bartoli, A.3
Puliti, M.4
Bistoni, F.5
-
8
-
-
0032516626
-
Feedback inhibition of macrophage tumor necrosis factor-α production by tristetraprolin
-
Carballo E., Lai WS, Blackshear PJ. 1998. Feedback inhibition of macrophage tumor necrosis factor-α production by tristetraprolin. Science 281: 1001-1005.
-
(1998)
Science
, vol.281
, pp. 1001-1005
-
-
Carballo, E.1
Lai, W.S.2
Blackshear, P.J.3
-
9
-
-
24944586285
-
Achieving stability of lipopolysaccharide-induced NF-κB activation
-
Covert M.W., Leung TH, Gaston JE, Baltimore D. 2005. Achieving stability of lipopolysaccharide-induced NF-κB activation. Science 309: 1854-1857.
-
(2005)
Science
, vol.309
, pp. 1854-1857
-
-
Covert, M.W.1
Leung, T.H.2
Gaston, J.E.3
Baltimore, D.4
-
10
-
-
0036839623
-
NF-κ B and TNF-α: A positive autocrine loop in human lung mast cells?
-
Coward W.R., Okayama Y, Sagara H, Wilson SJ, Holgate ST, Church M.K. 2002. NF-κ B and TNF-α: a positive autocrine loop in human lung mast cells? J Immunol 169: 5287-5293.
-
(2002)
J Immunol
, vol.169
, pp. 5287-5293
-
-
Coward, W.R.1
Okayama, Y.2
Sagara, H.3
Wilson, S.J.4
Holgate, S.T.5
Church, M.K.6
-
11
-
-
4043181927
-
Toll IL-1 receptors differ in their ability to promote the stabilization of adenosine and uridine-rich elements containing mRNA
-
Datta S., Novotny M, Li X, Tebo J, Hamilton TA. 2004. Toll IL-1 receptors differ in their ability to promote the stabilization of adenosine and uridine-rich elements containing mRNA. J Immunol 173: 2755-2761.
-
(2004)
J Immunol
, vol.173
, pp. 2755-2761
-
-
Datta, S.1
Novotny, M.2
Li, X.3
Tebo, J.4
Hamilton, T.A.5
-
12
-
-
34548241289
-
Tristetraprolin regulates TNF TNF-α mRNA stability via a proteasome dependent mechanism involving the combined action of the ERK and p38 pathways
-
Deleault K.M., Skinner SJ, Brooks SA. 2008. Tristetraprolin regulates TNF TNF-α mRNA stability via a proteasome dependent mechanism involving the combined action of the ERK and p38 pathways. Mol Immunol 45: 13-24.
-
(2008)
Mol Immunol
, vol.45
, pp. 13-24
-
-
Deleault, K.M.1
Skinner, S.J.2
Brooks, S.A.3
-
13
-
-
0035985185
-
Extracellular signal-regulated kinase phosphorylates tumor necrosis factor α-converting enzyme at threonine 735: A potential role in regulated shedding
-
Díaz-Rodríguez E., Montero JC, Esparís-Ogando A, Yuste L, Pandiella A. 2002. Extracellular signal-regulated kinase phosphorylates tumor necrosis factor α-converting enzyme at threonine 735: a potential role in regulated shedding. Mol Biol Cell 13: 2031-2044.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 2031-2044
-
-
Díaz-Rodríguez, E.1
Montero, J.C.2
Esparís-Ogando, A.3
Yuste, L.4
Pandiella, A.5
-
14
-
-
84871809302
-
STAR: Ultrafast universal RNA-seq aligner
-
Dobin A., Davis CA, Schlesinger F, Drenkow J, Zaleski C, Jha S, Batut P., Chaisson M, Gingeras TR. 2013. STAR: ultrafast universal RNA-seq aligner. Bioinformatics 29: 15-21.
-
(2013)
Bioinformatics
, vol.29
, pp. 15-21
-
-
Dobin, A.1
Davis, C.A.2
Schlesinger, F.3
Drenkow, J.4
Zaleski, C.5
Jha, S.6
Batut, P.7
Chaisson, M.8
Gingeras, T.R.9
-
15
-
-
0025789094
-
Enhancers and transcription factors controlling the inducibility of the tumor necrosis factor-α promoter in primary macrophages
-
Drouet C., Shakhov AN, Jongeneel CV. 1991. Enhancers and transcription factors controlling the inducibility of the tumor necrosis factor-α promoter in primary macrophages. J Immunol 147: 1694-1700.
-
(1991)
J Immunol
, vol.147
, pp. 1694-1700
-
-
Drouet, C.1
Shakhov, A.N.2
Jongeneel, C.V.3
-
16
-
-
0033573049
-
Ectodomain shedding of TGF-α and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades
-
Fan H., Derynck R. 1999. Ectodomain shedding of TGF-α and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades. EMBO J 18: 6962-6972.
-
(1999)
EMBO J
, vol.18
, pp. 6962-6972
-
-
Fan, H.1
Derynck, R.2
-
17
-
-
84858221706
-
Ensembl 2012
-
Flicek P., Amode MR, Barrell D, Beal K, Brent S, Carvalho-Silva D, Clapham P, Coates G, Fairley S, Fitzgerald S, et al. 2012. Ensembl 2012. Nucleic Acids Res 40: D84-D90.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. D84-D90
-
-
Flicek, P.1
Amode, M.R.2
Barrell, D.3
Beal, K.4
Brent, S.5
Carvalho-Silva, D.6
Clapham, P.7
Coates, G.8
Fairley, S.9
Fitzgerald, S.10
-
18
-
-
77954716659
-
TRIF signaling stimulates translation of TNF-α mRNA via prolonged activation of MK2
-
Gais P., Tiedje C, Altmayr F, Gaestel M, Weighardt H, Holzmann B. 2010. TRIF signaling stimulates translation of TNF-α mRNA via prolonged activation of MK2. J Immunol 184: 5842-5848.
-
(2010)
J Immunol
, vol.184
, pp. 5842-5848
-
-
Gais, P.1
Tiedje, C.2
Altmayr, F.3
Gaestel, M.4
Weighardt, H.5
Holzmann, B.6
-
19
-
-
0034698739
-
Immune cell activation by bacterial CpGDNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6
-
Häcker H., Vabulas RM, Takeuchi O, Hoshino K, Akira S, Wagner H. 2000. Immune cell activation by bacterial CpGDNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6. J Exp Med 192: 595-600.
-
(2000)
J Exp Med
, vol.192
, pp. 595-600
-
-
Häcker, H.1
Vabulas, R.M.2
Takeuchi, O.3
Hoshino, K.4
Akira, S.5
Wagner, H.6
-
20
-
-
0025828480
-
Interactive effects of the tumor necrosis factor promoter and 39-untranslated regions
-
Han J., Huez G, Beutler B. 1991a. Interactive effects of the tumor necrosis factor promoter and 39-untranslated regions. J Immunol 146: 1843-1848.
-
(1991)
J Immunol
, vol.146
, pp. 1843-1848
-
-
Han, J.1
Huez, G.2
Beutler, B.3
-
21
-
-
0025912577
-
Complex regulation of tumor necrosis factor mRNA turnover in lipopolysaccharide-activated macrophages
-
Han J.H., Beutler B, Huez G. 1991b. Complex regulation of tumor necrosis factor mRNA turnover in lipopolysaccharide-activated macrophages. Biochim Biophys Acta 1090: 22-28.
-
(1991)
Biochim Biophys Acta
, vol.1090
, pp. 22-28
-
-
Han, J.H.1
Beutler, B.2
Huez, G.3
-
22
-
-
60749124122
-
The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules
-
Hao S., Baltimore D. 2009. The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules. Nat Immunol 10: 281-288.
-
(2009)
Nat Immunol
, vol.10
, pp. 281-288
-
-
Hao, S.1
Baltimore, D.2
-
24
-
-
33644753147
-
Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element
-
Hitti E., Iakovleva T, Brook M, Deppenmeier S, Gruber AD, Radzioch D., Clark AR, Blackshear PJ, Kotlyarov A, Gaestel M. 2006. Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element. Mol Cell Biol 26: 2399-2407.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2399-2407
-
-
Hitti, E.1
Iakovleva, T.2
Brook, M.3
Deppenmeier, S.4
Gruber, A.D.5
Radzioch, D.6
Clark, A.R.7
Blackshear, P.J.8
Kotlyarov, A.9
Gaestel, M.10
-
25
-
-
0347146027
-
Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways
-
Hoebe K., Janssen EM, Kim SO, Alexopoulou L, Flavell RA, Han J, Beutler B. 2003. Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways. Nat Immunol 4: 1223-1229.
-
(2003)
Nat Immunol
, vol.4
, pp. 1223-1229
-
-
Hoebe, K.1
Janssen, E.M.2
Kim, S.O.3
Alexopoulou, L.4
Flavell, R.A.5
Han, J.6
Beutler, B.7
-
26
-
-
0037044575
-
The IκB-NF-κB signaling module: Temporal control and selective gene activation
-
Hoffmann A., Levchenko A, Scott ML, Baltimore D. 2002. The IκB-NF-κB signaling module: temporal control and selective gene activation. Science 298: 1241-1245.
-
(2002)
Science
, vol.298
, pp. 1241-1245
-
-
Hoffmann, A.1
Levchenko, A.2
Scott, M.L.3
Baltimore, D.4
-
27
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
Kawai T., Adachi O, Ogawa T, Takeda K, Akira S. 1999. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 11: 115-122.
-
(1999)
Immunity
, vol.11
, pp. 115-122
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
28
-
-
33747388013
-
IκBe provides negative feedback to control NF-κB oscillations, signaling dynamics, and inflammatory gene expression
-
Kearns J.D., Basak S, Werner SL, Huang CS, Hoffmann A. 2006. IκBe provides negative feedback to control NF-κB oscillations, signaling dynamics, and inflammatory gene expression. J Cell Biol 173: 659-664.
-
(2006)
J Cell Biol
, vol.173
, pp. 659-664
-
-
Kearns, J.D.1
Basak, S.2
Werner, S.L.3
Huang, C.S.4
Hoffmann, A.5
-
29
-
-
0024566140
-
The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection
-
Kindler V., Sappino AP, Grau GE, Piguet PF, Vassalli P. 1989. The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection. Cell 56: 731- 740.
-
(1989)
Cell
, vol.56
, pp. 731-740
-
-
Kindler, V.1
Sappino, A.P.2
Grau, G.E.3
Piguet, P.F.4
Vassalli, P.5
-
30
-
-
0037079054
-
Computational systems biology
-
Kitano H. 2002. Computational systems biology. Nature 420: 206-210.
-
(2002)
Nature
, vol.420
, pp. 206-210
-
-
Kitano, H.1
-
31
-
-
0033103805
-
Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: Implications for joint and gut-associated immunopathologies
-
Kontoyiannis D., Pasparakis M, Pizarro TT, Cominelli F, Kollias G. 1999. Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: implications for joint and gut-associated immunopathologies. Immunity 10: 387-398.
-
(1999)
Immunity
, vol.10
, pp. 387-398
-
-
Kontoyiannis, D.1
Pasparakis, M.2
Pizarro, T.T.3
Cominelli, F.4
Kollias, G.5
-
32
-
-
0033145354
-
MAPKAP kinase 2 is essential for LPS-induced TNF-α biosynthesis
-
Kotlyarov A., Neininger A, Schubert C, Eckert R, Birchmeier C, Volk H.D., Gaestel M. 1999. MAPKAP kinase 2 is essential for LPS-induced TNF-α biosynthesis. Nat Cell Biol 1: 94-97.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 94-97
-
-
Kotlyarov, A.1
Neininger, A.2
Schubert, C.3
Eckert, R.4
Birchmeier, C.5
Volk, H.D.6
Gaestel, M.7
-
33
-
-
17044396389
-
Autocrine activation of microglia by tumor necrosis factor-α
-
Kuno R., Wang J, Kawanokuchi J, Takeuchi H, Mizuno T, Suzumura A. 2005. Autocrine activation of microglia by tumor necrosis factor-α. J Neuroimmunol 162: 89-96.
-
(2005)
J Neuroimmunol
, vol.162
, pp. 89-96
-
-
Kuno, R.1
Wang, J.2
Kawanokuchi, J.3
Takeuchi, H.4
Mizuno, T.5
Suzumura, A.6
-
34
-
-
0033049125
-
Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor α mRNA
-
Lai W.S., Carballo E, Strum JR, Kennington EA, Phillips RS, Blackshear P.J. 1999. Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor α mRNA. Mol Cell Biol 19: 4311-4323.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 4311-4323
-
-
Lai, W.S.1
Carballo, E.2
Strum, J.R.3
Kennington, E.A.4
Phillips, R.S.5
Blackshear, P.J.6
-
35
-
-
77951187551
-
A noisy paracrine signal determines the cellular NF-κB response to lipopolysaccharide
-
Lee T.K., Denny EM, Sanghvi JC, Gaston JE, Maynard ND, Hughey J.J., Covert MW. 2009. A noisy paracrine signal determines the cellular NF-κB response to lipopolysaccharide. Sci Signal 2: ra65.
-
(2009)
Sci Signal
, vol.2
-
-
Lee, T.K.1
Denny, E.M.2
Sanghvi, J.C.3
Gaston, J.E.4
Maynard, N.D.5
Hughey, J.J.6
Covert, M.W.7
-
36
-
-
33947239704
-
TLR4-mediated survival of macrophages is MyD88 dependent and requires TNF-α autocrine signalling
-
Lombardo E., Alvarez-Barrientos A, Maroto B, Boscá L, Knaus UG. 2007. TLR4-mediated survival of macrophages is MyD88 dependent and requires TNF-α autocrine signalling. J Immunol 178: 3731-3739.
-
(2007)
J Immunol
, vol.178
, pp. 3731-3739
-
-
Lombardo, E.1
Alvarez-Barrientos, A.2
Maroto, B.3
Boscá, L.4
Knaus, U.G.5
-
37
-
-
0025333699
-
Tumour necrosis factor-α and interferon-γ production measured at the single cell level in normal and inflamed human intestine
-
MacDonald TT, Hutchings P, Choy MY, Murch S, Cooke A. 1990. Tumour necrosis factor-α and interferon-γ production measured at the single cell level in normal and inflamed human intestine. Clin Exp Immunol 81: 301-305.
-
(1990)
Clin Exp Immunol
, vol.81
, pp. 301-305
-
-
McDonald, T.T.1
Hutchings, P.2
Choy, M.Y.3
Murch, S.4
Cooke, A.5
-
38
-
-
0036622949
-
Post-transcriptional regulation of TNF-α during in vitro differentiation of human monocytes/macrophages in primary culture
-
MacKenzie S, Fernández-Troy N, Espel E. 2002. Post-transcriptional regulation of TNF-α during in vitro differentiation of human monocytes/macrophages in primary culture. J Leukoc Biol 71: 1026-1032.
-
(2002)
J Leukoc Biol
, vol.71
, pp. 1026-1032
-
-
McKenzie, S.1
Fernández-Troy, N.2
Espel, E.3
-
39
-
-
64549144670
-
Programming with models: Modularity and abstraction provide powerful capabilities for systems biology
-
Mallavarapu A., Thomson M, Ullian B, Gunawardena J. 2009. Programming with models: modularity and abstraction provide powerful capabilities for systems biology. J R Soc Interface R Soc 6: 257-270.
-
(2009)
J R Soc Interface R Soc
, vol.6
, pp. 257-270
-
-
Mallavarapu, A.1
Thomson, M.2
Ullian, B.3
Gunawardena, J.4
-
40
-
-
84862909285
-
iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS
-
McIlwain D.R., Lang PA, Maretzky T, Hamada K, Ohishi K, Maney S.K., Berger T, Murthy A, Duncan G, Xu HC, et al. 2012. iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS. Science 335: 229-232.
-
(2012)
Science
, vol.335
, pp. 229-232
-
-
McIlwain, D.R.1
Lang, P.A.2
Maretzky, T.3
Hamada, K.4
Ohishi, K.5
Maney, S.K.6
Berger, T.7
Murthy, A.8
Duncan, G.9
Xu, H.C.10
-
41
-
-
34249720998
-
Cytokines in the pathogenesis of rheumatoid arthritis
-
McInnes I.B., Schett G. 2007. Cytokines in the pathogenesis of rheumatoid arthritis. Nat Rev Immunol 7: 429-442.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 429-442
-
-
McInnes, I.B.1
Schett, G.2
-
42
-
-
56749174940
-
Exploring the full spectrum of macrophage activation
-
Mosser D.M., Edwards JP. 2008. Exploring the full spectrum of macrophage activation. Nat Rev Immunol 8: 958-969.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 958-969
-
-
Mosser, D.M.1
Edwards, J.P.2
-
43
-
-
0027486125
-
Location of tumour necrosis factor α by immunohistochemistry in chronic inflammatory bowel disease
-
Murch S.H., Braegger CP, Walker-Smith JA, MacDonald TT. 1993. Location of tumour necrosis factor α by immunohistochemistry in chronic inflammatory bowel disease. Gut 34: 1705-1709.
-
(1993)
Gut
, vol.34
, pp. 1705-1709
-
-
Murch, S.H.1
Braegger, C.P.2
Walker-Smith, J.A.3
McDonald, T.T.4
-
44
-
-
0033572827
-
A cis-acting element in the 39-untranslated region of human TNF-α mRNA renders splicing dependent on the activation of protein kinase PKR
-
Osman F., Jarrous N, Ben-Asouli Y, Kaempfer R. 1999. A cis-acting element in the 39-untranslated region of human TNF-α mRNA renders splicing dependent on the activation of protein kinase PKR. Genes Dev 13: 3280-3293.
-
(1999)
Genes Dev
, vol.13
, pp. 3280-3293
-
-
Osman, F.1
Jarrous, N.2
Ben-Asouli, Y.3
Kaempfer, R.4
-
45
-
-
22344431978
-
Dynamic characteristics of transient responses
-
Ozaki Y., Sasagawa S, Kuroda S. 2005. Dynamic characteristics of transient responses. J Biochem 137: 659-663.
-
(2005)
J Biochem
, vol.137
, pp. 659-663
-
-
Ozaki, Y.1
Sasagawa, S.2
Kuroda, S.3
-
47
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak A., He X, Smirnova I, Liu MY, Van Huffel C, Du X, Birdwell D., Alejos E, Silva M, Galanos C, et al. 1998. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282: 2085-2088.
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
Van Huffel, C.5
Du, X.6
Birdwell, D.7
Alejos, E.8
Silva, M.9
Galanos, C.10
-
48
-
-
84874765320
-
Encoding and decoding cellular information through signaling dynamics
-
Purvis J.E., Lahav G. 2013. Encoding and decoding cellular information through signaling dynamics. Cell 152: 945-956.
-
(2013)
Cell
, vol.152
, pp. 945-956
-
-
Purvis, J.E.1
Lahav, G.2
-
49
-
-
79959537254
-
NF-κB signal triggering and termination by tumor necrosis factor receptor 2
-
Rodríguez M., Cabal-Hierro L, Carcedo MT, Iglesias JM, Artime N, Darnay BG, Lazo PS. 2011. NF-κB signal triggering and termination by tumor necrosis factor receptor 2. J Biol Chem 286: 22814-22824.
-
(2011)
J Biol Chem
, vol.286
, pp. 22814-22824
-
-
Rodríguez, M.1
Cabal-Hierro, L.2
Carcedo, M.T.3
Iglesias, J.M.4
Artime, N.5
Darnay, B.G.6
Lazo, P.S.7
-
50
-
-
33845807361
-
The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK
-
Ronkina N., Kotlyarov A, Dittrich-Breiholz O, Kracht M, Hitti E, Milarski K., Askew R, Marusic S, Lin L-L, Gaestel M, et al. 2007. The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK. Mol Cell Biol 27: 170-181.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 170-181
-
-
Ronkina, N.1
Kotlyarov, A.2
Dittrich-Breiholz, O.3
Kracht, M.4
Hitti, E.5
Milarski, K.6
Askew, R.7
Marusic, S.8
Lin, L.-L.9
Gaestel, M.10
-
51
-
-
0141923690
-
Toll/IL-1 receptor domain-containing adaptor inducing IFN-β (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-κ B and IFN-regulatory factor-3, in the Toll-like receptor signaling
-
Sato S., Sugiyama M, Yamamoto M, Watanabe Y, Kawai T, Takeda K., Akira S. 2003. Toll/IL-1 receptor domain-containing adaptor inducing IFN-β (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-κ B and IFN-regulatory factor-3, in the Toll-like receptor signaling. J Immunol 171: 4304-4310.
-
(2003)
J Immunol
, vol.171
, pp. 4304-4310
-
-
Sato, S.1
Sugiyama, M.2
Yamamoto, M.3
Watanabe, Y.4
Kawai, T.5
Takeda, K.6
Akira, S.7
-
52
-
-
21044444181
-
ERKmediated phosphorylation of Thr735 in TNFα-converting enzyme and its potential role in TACE protein trafficking
-
Soond S.M., Everson B, Riches DWH, Murphy G. 2005. ERKmediated phosphorylation of Thr735 in TNFα-converting enzyme and its potential role in TACE protein trafficking. J Cell Sci 118: 2371-2380.
-
(2005)
J Cell Sci
, vol.118
, pp. 2371-2380
-
-
Soond, S.M.1
Everson, B.2
Riches, D.W.H.3
Murphy, G.4
-
53
-
-
1942471656
-
MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay
-
Stoecklin G., Stubbs T, Kedersha N,Wax S, Rigby WFC, Blackwell TK, Anderson P. 2004. MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay. EMBO J 23: 1313-1324.
-
(2004)
EMBO J
, vol.23
, pp. 1313-1324
-
-
Stoecklin, G.1
Stubbs, T.2
Kedersha, N.3
Wax, S.4
Rigby, W.F.C.5
Blackwell, T.K.6
Anderson, P.7
-
54
-
-
77950343791
-
Pattern recognition receptors and inflammation
-
Takeuchi O., Akira S. 2010. Pattern recognition receptors and inflammation. Cell 140: 805-820.
-
(2010)
Cell
, vol.140
, pp. 805-820
-
-
Takeuchi, O.1
Akira, S.2
-
55
-
-
9244228003
-
Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities
-
Topisirovic I., Ruiz-Gutierrez M, Borden KLB. 2004. Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities. Cancer Res 64: 8639-8642.
-
(2004)
Cancer Res
, vol.64
, pp. 8639-8642
-
-
Topisirovic, I.1
Ruiz-Gutierrez, M.2
Borden, K.L.B.3
-
56
-
-
0032540244
-
The phosphorylation of eukaryotic initiation factor eIF4E in response to phorbol esters, cell stresses, and cytokines is mediated by distinct MAP kinase pathways
-
Wang X., Flynn A,Waskiewicz AJ,Webb BL, Vries RG, Baines IA, Cooper J.A., Proud CG. 1998. The phosphorylation of eukaryotic initiation factor eIF4E in response to phorbol esters, cell stresses, and cytokines is mediated by distinct MAP kinase pathways. J Biol Chem 273: 9373-9377.
-
(1998)
J Biol Chem
, vol.273
, pp. 9373-9377
-
-
Wang, X.1
Flynn, A.2
Waskiewicz, A.J.3
Webb, B.L.4
Vries, R.G.5
Baines, I.A.6
Cooper, J.A.7
Proud, C.G.8
-
57
-
-
80052075499
-
Regulation of lipopolysaccharideinduced translation of tumor necrosis factor-α by the toll-like receptor 4 adaptor protein TRAM
-
Wang L., Trebicka E, Fu Y, Waggoner L, Akira S, Fitzgerald KA, Kagan J.C., Cherayil BJ. 2011. Regulation of lipopolysaccharideinduced translation of tumor necrosis factor-α by the toll-like receptor 4 adaptor protein TRAM. J Innate Immun 3: 437- 446.
-
(2011)
J Innate Immun
, vol.3
, pp. 437-446
-
-
Wang, L.1
Trebicka, E.2
Fu, Y.3
Waggoner, L.4
Akira, S.5
Fitzgerald, K.A.6
Kagan, J.C.7
Cherayil, B.J.8
-
59
-
-
24944489952
-
Stimulus specificity of gene expression programs determined by temporal control of IKK activity
-
Werner S.L., Barken D, Hoffmann A. 2005. Stimulus specificity of gene expression programs determined by temporal control of IKK activity. Science 309: 1857-1861.
-
(2005)
Science
, vol.309
, pp. 1857-1861
-
-
Werner, S.L.1
Barken, D.2
Hoffmann, A.3
-
60
-
-
48749085156
-
Encoding NF-κB temporal control in response to TNF: Distinct roles for the negative regulators IκBα and A20
-
Werner S.L., Kearns JD, Zadorozhnaya V, Lynch C, O'Dea E, Boldin M.P., Ma A, Baltimore D, Hoffmann A. 2008. Encoding NF-κB temporal control in response to TNF: distinct roles for the negative regulators IκBα and A20. Genes Dev 22: 2093- 2101.
-
(2008)
Genes Dev
, vol.22
, pp. 2093-2101
-
-
Werner, S.L.1
Kearns, J.D.2
Zadorozhnaya, V.3
Lynch, C.4
O'Dea, E.5
Boldin, M.P.6
Ma, A.7
Baltimore, D.8
Hoffmann, A.9
-
61
-
-
0031423761
-
MyD88: An adapter that recruits IRAK to the IL-1 receptor complex
-
Wesche H., Henzel WJ, ShillinglawW, Li S, Cao Z. 1997. MyD88: an adapter that recruits IRAK to the IL-1 receptor complex. Immunity 7: 837-847.
-
(1997)
Immunity
, vol.7
, pp. 837-847
-
-
Wesche, H.1
Henzel, W.J.2
Shillinglaw, W.3
Li, S.4
Cao, Z.5
-
62
-
-
0027274028
-
Tumor necrosis factor α as an autocrine and paracrine growth factor for ovarian cancer: Monokine induction of tumor cell proliferation and tumor necrosis factor α expression
-
Wu S., Boyer CM, Whitaker RS, Berchuck A,Wiener JR,Weinberg JB, Bast RC Jr. 1993. Tumor necrosis factor α as an autocrine and paracrine growth factor for ovarian cancer: monokine induction of tumor cell proliferation and tumor necrosis factor α expression. Cancer Res 53: 1939-1944.
-
(1993)
Cancer Res
, vol.53
, pp. 1939-1944
-
-
Wu, S.1
Boyer, C.M.2
Whitaker, R.S.3
Berchuck, A.4
Wiener, J.R.5
Weinberg, J.B.6
Bast, R.C.7
-
63
-
-
0034660130
-
LPS induces apoptosis in macrophages mostly through the autocrine production of TNF-α
-
Xaus J., Comalada M, Valledor AF, Lloberas J, López-Soriano F, Argilés J.M., Bogdan C, Celada A. 2000. LPS induces apoptosis in macrophages mostly through the autocrine production of TNF-α. Blood 95: 3823-3831.
-
(2000)
Blood
, vol.95
, pp. 3823-3831
-
-
Xaus, J.1
Comalada, M.2
Valledor, A.F.3
Lloberas, J.4
López-Soriano, F.5
Argilés, J.M.6
Bogdan, C.7
Celada, A.8
-
64
-
-
76849107016
-
Direct activation of TACE-mediated ectodomain shedding by p38 MAP kinase regulates EGF receptor- dependent cell proliferation
-
Xu P., Derynck R. 2010. Direct activation of TACE-mediated ectodomain shedding by p38 MAP kinase regulates EGF receptor- dependent cell proliferation. Mol Cell 37: 551-566.
-
(2010)
Mol Cell
, vol.37
, pp. 551-566
-
-
Xu, P.1
Derynck, R.2
-
65
-
-
0043176281
-
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
-
Yamamoto M., Sato S, Hemmi H, Hoshino K, Kaisho T, Sanjo H, Takeuchi O., Sugiyama M, Okabe M, Takeda K, et al. 2003. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 301: 640-643.
-
(2003)
Science
, vol.301
, pp. 640-643
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Hoshino, K.4
Kaisho, T.5
Sanjo, H.6
Takeuchi, O.7
Sugiyama, M.8
Okabe, M.9
Takeda, K.10
|