-
1
-
-
85047692516
-
Signalling pathways of the TNF superfamily: a double-edged sword
-
Aggarwal B.B. Signalling pathways of the TNF superfamily: a double-edged sword. Nat. Rev. Immunol. 2003, 3:745-756.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 745-756
-
-
Aggarwal, B.B.1
-
2
-
-
64849104716
-
Pulsatile stimulation determines timing and specificity of NF-kappaB-dependent transcription
-
Ashall L., Horton C.A., Nelson D.E., Paszek P., Harper C.V., Sillitoe K., Ryan S., Spiller D.G., Unitt J.F., Broomhead D.S., et al. Pulsatile stimulation determines timing and specificity of NF-kappaB-dependent transcription. Science 2009, 324:242-246.
-
(2009)
Science
, vol.324
, pp. 242-246
-
-
Ashall, L.1
Horton, C.A.2
Nelson, D.E.3
Paszek, P.4
Harper, C.V.5
Sillitoe, K.6
Ryan, S.7
Spiller, D.G.8
Unitt, J.F.9
Broomhead, D.S.10
-
3
-
-
0023724778
-
I kappa B: a specific inhibitor of the NF-kappa B transcription factor
-
Baeuerle P.A., Baltimore D. I kappa B: a specific inhibitor of the NF-kappa B transcription factor. Science 1988, 242:540-546.
-
(1988)
Science
, vol.242
, pp. 540-546
-
-
Baeuerle, P.A.1
Baltimore, D.2
-
4
-
-
0029874138
-
The NF-kappa B and I kappa B proteins: new discoveries and insights
-
Baldwin A.S. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu. Rev. Immunol. 1996, 14:649-683.
-
(1996)
Annu. Rev. Immunol.
, vol.14
, pp. 649-683
-
-
Baldwin, A.S.1
-
5
-
-
33745287724
-
Noise in protein expression scales with natural protein abundance
-
Bar-Even A., Paulsson J., Maheshri N., Carmi M., O'Shea E., Pilpel Y., Barkai N. Noise in protein expression scales with natural protein abundance. Nat. Genet. 2006, 38:636-643.
-
(2006)
Nat. Genet.
, vol.38
, pp. 636-643
-
-
Bar-Even, A.1
Paulsson, J.2
Maheshri, N.3
Carmi, M.4
O'Shea, E.5
Pilpel, Y.6
Barkai, N.7
-
6
-
-
0033596127
-
Control of apoptosis by Rel/NF-kappaB transcription factors
-
Barkett M., Gilmore T.D. Control of apoptosis by Rel/NF-kappaB transcription factors. Oncogene 1999, 18:6910-6924.
-
(1999)
Oncogene
, vol.18
, pp. 6910-6924
-
-
Barkett, M.1
Gilmore, T.D.2
-
7
-
-
33845764296
-
A guided tour into subcellular colocalization analysis in light microscopy
-
Bolte S., Cordelières F.P. A guided tour into subcellular colocalization analysis in light microscopy. J.Microsc. 2006, 224:213-232.
-
(2006)
J.Microsc.
, vol.224
, pp. 213-232
-
-
Bolte, S.1
Cordelières, F.P.2
-
8
-
-
0027462682
-
Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha
-
Brown K., Park S., Kanno T., Franzoso G., Siebenlist U. Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha. Proc. Natl. Acad. Sci. USA 1993, 90:2532-2536.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 2532-2536
-
-
Brown, K.1
Park, S.2
Kanno, T.3
Franzoso, G.4
Siebenlist, U.5
-
9
-
-
33845792555
-
CellProfiler: image analysis software for identifying and quantifying cell phenotypes
-
Carpenter A.E., Jones T.R., Lamprecht M.R., Clarke C., Kang I.H., Friman O., Guertin D.A., Chang J.H., Lindquist R.A., Moffat J., et al. CellProfiler: image analysis software for identifying and quantifying cell phenotypes. Genome Biol. 2006, 7:R100.
-
(2006)
Genome Biol.
, vol.7
-
-
Carpenter, A.E.1
Jones, T.R.2
Lamprecht, M.R.3
Clarke, C.4
Kang, I.H.5
Friman, O.6
Guertin, D.A.7
Chang, J.H.8
Lindquist, R.A.9
Moffat, J.10
-
10
-
-
79952173562
-
The specificity of innate immune responses is enforced by repression of interferon response elements by NF-κB p50
-
Cheng C.S., Feldman K.E., Lee J., Verma S., Huang D.B., Huynh K., Chang M., Ponomarenko J.V., Sun S.C., Benedict C.A., et al. The specificity of innate immune responses is enforced by repression of interferon response elements by NF-κB p50. Sci. Signal. 2011, 4:ra11.
-
(2011)
Sci. Signal.
, vol.4
-
-
Cheng, C.S.1
Feldman, K.E.2
Lee, J.3
Verma, S.4
Huang, D.B.5
Huynh, K.6
Chang, M.7
Ponomarenko, J.V.8
Sun, S.C.9
Benedict, C.A.10
-
11
-
-
80054841161
-
Information transduction capacity of noisy biochemical signaling networks
-
Cheong R., Rhee A., Wang C.J., Nemenman I., Levchenko A. Information transduction capacity of noisy biochemical signaling networks. Science 2011, 334:354-358.
-
(2011)
Science
, vol.334
, pp. 354-358
-
-
Cheong, R.1
Rhee, A.2
Wang, C.J.3
Nemenman, I.4
Levchenko, A.5
-
12
-
-
71149092283
-
Dynamics and variability of ERK2 response to EGF in individual living cells
-
Cohen-Saidon C., Cohen A.A., Sigal A., Liron Y., Alon U. Dynamics and variability of ERK2 response to EGF in individual living cells. Mol. Cell 2009, 36:885-893.
-
(2009)
Mol. Cell
, vol.36
, pp. 885-893
-
-
Cohen-Saidon, C.1
Cohen, A.A.2
Sigal, A.3
Liron, Y.4
Alon, U.5
-
13
-
-
50149090966
-
Variability and robustness in Tcell activation from regulated heterogeneity in protein levels
-
Feinerman O., Veiga J., Dorfman J.R., Germain R.N., Altan-Bonnet G. Variability and robustness in Tcell activation from regulated heterogeneity in protein levels. Science 2008, 321:1081-1084.
-
(2008)
Science
, vol.321
, pp. 1081-1084
-
-
Feinerman, O.1
Veiga, J.2
Dorfman, J.R.3
Germain, R.N.4
Altan-Bonnet, G.5
-
14
-
-
84861133687
-
Exploring the contextual sensitivity of factors that determine cell-to-cell variability in receptor-mediated apoptosis
-
Gaudet S., Spencer S.L., Chen W.W., Sorger P.K. Exploring the contextual sensitivity of factors that determine cell-to-cell variability in receptor-mediated apoptosis. PLoS Comput. Biol. 2012, 8:e1002482.
-
(2012)
PLoS Comput. Biol.
, vol.8
-
-
Gaudet, S.1
Spencer, S.L.2
Chen, W.W.3
Sorger, P.K.4
-
15
-
-
54949147176
-
New regulators of NF-kappaB in inflammation
-
Ghosh S., Hayden M.S. New regulators of NF-kappaB in inflammation. Nat. Rev. Immunol. 2008, 8:837-848.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 837-848
-
-
Ghosh, S.1
Hayden, M.S.2
-
16
-
-
71149092489
-
Evidence that fold-change, and not absolute level, of beta-catenin dictates Wnt signaling
-
Goentoro L., Kirschner M.W. Evidence that fold-change, and not absolute level, of beta-catenin dictates Wnt signaling. Mol. Cell 2009, 36:872-884.
-
(2009)
Mol. Cell
, vol.36
, pp. 872-884
-
-
Goentoro, L.1
Kirschner, M.W.2
-
17
-
-
71149099313
-
The incoherent feedforward loop can provide fold-change detection in gene regulation
-
Goentoro L., Shoval O., Kirschner M.W., Alon U. The incoherent feedforward loop can provide fold-change detection in gene regulation. Mol. Cell 2009, 36:894-899.
-
(2009)
Mol. Cell
, vol.36
, pp. 894-899
-
-
Goentoro, L.1
Shoval, O.2
Kirschner, M.W.3
Alon, U.4
-
18
-
-
0025812292
-
Characterization of an immediate-early gene induced in adherent monocytes that encodes I kappa B-like activity
-
Haskill S., Beg A.A., Tompkins S.M., Morris J.S., Yurochko A.D., Sampson-Johannes A., Mondal K., Ralph P., Baldwin A.S. Characterization of an immediate-early gene induced in adherent monocytes that encodes I kappa B-like activity. Cell 1991, 65:1281-1289.
-
(1991)
Cell
, vol.65
, pp. 1281-1289
-
-
Haskill, S.1
Beg, A.A.2
Tompkins, S.M.3
Morris, J.S.4
Yurochko, A.D.5
Sampson-Johannes, A.6
Mondal, K.7
Ralph, P.8
Baldwin, A.S.9
-
19
-
-
4444376712
-
Signaling to NF-kappaB
-
Hayden M.S., Ghosh S. Signaling to NF-kappaB. Genes Dev. 2004, 18:2195-2224.
-
(2004)
Genes Dev.
, vol.18
, pp. 2195-2224
-
-
Hayden, M.S.1
Ghosh, S.2
-
20
-
-
38849199203
-
Shared principles in NF-kappaB signaling
-
Hayden M.S., Ghosh S. Shared principles in NF-kappaB signaling. Cell 2008, 132:344-362.
-
(2008)
Cell
, vol.132
, pp. 344-362
-
-
Hayden, M.S.1
Ghosh, S.2
-
21
-
-
0037044575
-
The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation
-
Hoffmann A., Levchenko A., Scott M.L., Baltimore D. The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation. Science 2002, 298:1241-1245.
-
(2002)
Science
, vol.298
, pp. 1241-1245
-
-
Hoffmann, A.1
Levchenko, A.2
Scott, M.L.3
Baltimore, D.4
-
22
-
-
0036009115
-
NF-kappaB at the crossroads of life and death
-
Karin M., Lin A. NF-kappaB at the crossroads of life and death. Nat. Immunol. 2002, 3:221-227.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 221-227
-
-
Karin, M.1
Lin, A.2
-
23
-
-
0026699666
-
Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elements
-
Krikos A., Laherty C.D., Dixit V.M. Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elements. J.Biol. Chem. 1992, 267:17971-17976.
-
(1992)
J.Biol. Chem.
, vol.267
, pp. 17971-17976
-
-
Krikos, A.1
Laherty, C.D.2
Dixit, V.M.3
-
24
-
-
0027384590
-
NF-kappa B subunit-specific regulation of the interleukin-8 promoter
-
Kunsch C., Rosen C.A. NF-kappa B subunit-specific regulation of the interleukin-8 promoter. Mol. Cell. Biol. 1993, 13:6137-6146.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 6137-6146
-
-
Kunsch, C.1
Rosen, C.A.2
-
25
-
-
0031052091
-
Constitutive expression of p50 homodimer in freshly isolated human monocytes decreases with invitro and invivo differentiation: a possible mechanism influencing human immunodeficiency virus replication in monocytes and mature macrophages
-
Lewin S.R., Lambert P., Deacon N.J., Mills J., Crowe S.M. Constitutive expression of p50 homodimer in freshly isolated human monocytes decreases with invitro and invivo differentiation: a possible mechanism influencing human immunodeficiency virus replication in monocytes and mature macrophages. J.Virol. 1997, 71:2114-2119.
-
(1997)
J.Virol.
, vol.71
, pp. 2114-2119
-
-
Lewin, S.R.1
Lambert, P.2
Deacon, N.J.3
Mills, J.4
Crowe, S.M.5
-
26
-
-
31544441610
-
Distinct role of macrophages in different tumor microenvironments
-
Lewis C.E., Pollard J.W. Distinct role of macrophages in different tumor microenvironments. Cancer Res. 2006, 66:605-612.
-
(2006)
Cancer Res.
, vol.66
, pp. 605-612
-
-
Lewis, C.E.1
Pollard, J.W.2
-
27
-
-
0035375064
-
TNF-alpha regulates early differentiation of C2C12 myoblasts in an autocrine fashion
-
Li Y.P., Schwartz R.J. TNF-alpha regulates early differentiation of C2C12 myoblasts in an autocrine fashion. FASEB J. 2001, 15:1413-1415.
-
(2001)
FASEB J.
, vol.15
, pp. 1413-1415
-
-
Li, Y.P.1
Schwartz, R.J.2
-
28
-
-
0038165436
-
RelB forms transcriptionally inactive complexes with RelA/p65
-
Marienfeld R., May M.J., Berberich I., Serfling E., Ghosh S., Neumann M. RelB forms transcriptionally inactive complexes with RelA/p65. J.Biol. Chem. 2003, 278:19852-19860.
-
(2003)
J.Biol. Chem.
, vol.278
, pp. 19852-19860
-
-
Marienfeld, R.1
May, M.J.2
Berberich, I.3
Serfling, E.4
Ghosh, S.5
Neumann, M.6
-
29
-
-
8344248747
-
Cancer research. Inflammation and cancer: the link grows stronger
-
Marx J. Cancer research. Inflammation and cancer: the link grows stronger. Science 2004, 306:966-968.
-
(2004)
Science
, vol.306
, pp. 966-968
-
-
Marx, J.1
-
30
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
Micheau O., Tschopp J. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 2003, 114:181-190.
-
(2003)
Cell
, vol.114
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
31
-
-
0034743199
-
NF-kappaB signals induce the expression of c-FLIP
-
Micheau O., Lens S., Gaide O., Alevizopoulos K., Tschopp J. NF-kappaB signals induce the expression of c-FLIP. Mol. Cell. Biol. 2001, 21:5299-5305.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 5299-5305
-
-
Micheau, O.1
Lens, S.2
Gaide, O.3
Alevizopoulos, K.4
Tschopp, J.5
-
32
-
-
7444254365
-
Oscillations in NF-kappaB signaling control the dynamics of gene expression
-
Nelson D.E., Ihekwaba A.E., Elliott M., Johnson J.R., Gibney C.A., Foreman B.E., Nelson G., See V., Horton C.A., Spiller D.G., et al. Oscillations in NF-kappaB signaling control the dynamics of gene expression. Science 2004, 306:704-708.
-
(2004)
Science
, vol.306
, pp. 704-708
-
-
Nelson, D.E.1
Ihekwaba, A.E.2
Elliott, M.3
Johnson, J.R.4
Gibney, C.A.5
Foreman, B.E.6
Nelson, G.7
See, V.8
Horton, C.A.9
Spiller, D.G.10
-
34
-
-
77953496625
-
The NF-kappaB family of transcription factors and its regulation
-
Oeckinghaus A., Ghosh S. The NF-kappaB family of transcription factors and its regulation. Cold Spring Harb. Perspect. Biol. 2009, 1:a000034.
-
(2009)
Cold Spring Harb. Perspect. Biol.
, vol.1
-
-
Oeckinghaus, A.1
Ghosh, S.2
-
35
-
-
0033596121
-
Activators and target genes of Rel/NF-kappaB transcription factors
-
Pahl H.L. Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene 1999, 18:6853-6866.
-
(1999)
Oncogene
, vol.18
, pp. 6853-6866
-
-
Pahl, H.L.1
-
36
-
-
0034637546
-
Mechanism of kappa B DNA binding by Rel/NF-kappa B dimers
-
Phelps C.B., Sengchanthalangsy L.L., Malek S., Ghosh G. Mechanism of kappa B DNA binding by Rel/NF-kappa B dimers. J.Biol. Chem. 2000, 275:24392-24399.
-
(2000)
J.Biol. Chem.
, vol.275
, pp. 24392-24399
-
-
Phelps, C.B.1
Sengchanthalangsy, L.L.2
Malek, S.3
Ghosh, G.4
-
37
-
-
53349161901
-
Imaging individual mRNA molecules using multiple singly labeled probes
-
Raj A., van den Bogaard P., Rifkin S.A., van Oudenaarden A., Tyagi S. Imaging individual mRNA molecules using multiple singly labeled probes. Nat. Methods 2008, 5:877-879.
-
(2008)
Nat. Methods
, vol.5
, pp. 877-879
-
-
Raj, A.1
van den Bogaard, P.2
Rifkin, S.A.3
van Oudenaarden, A.4
Tyagi, S.5
-
38
-
-
33645508531
-
Chronic inflammation: a common and important factor in the pathogenesis of neoplasia
-
Schottenfeld D., Beebe-Dimmer J. Chronic inflammation: a common and important factor in the pathogenesis of neoplasia. CA Cancer J. Clin. 2006, 56:69-83.
-
(2006)
CA Cancer J. Clin.
, vol.56
, pp. 69-83
-
-
Schottenfeld, D.1
Beebe-Dimmer, J.2
-
39
-
-
0027168948
-
The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms
-
Scott M.L., Fujita T., Liou H.C., Nolan G.P., Baltimore D. The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms. Genes Dev. 1993, 7(7A):1266-1276.
-
(1993)
Genes Dev.
, vol.7 A
, Issue.7
, pp. 1266-1276
-
-
Scott, M.L.1
Fujita, T.2
Liou, H.C.3
Nolan, G.P.4
Baltimore, D.5
-
40
-
-
83855162723
-
Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-κB family DNA binding
-
Siggers T., Chang A.B., Teixeira A., Wong D., Williams K.J., Ahmed B., Ragoussis J., Udalova I.A., Smale S.T., Bulyk M.L. Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-κB family DNA binding. Nat. Immunol. 2012, 13:95-102.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 95-102
-
-
Siggers, T.1
Chang, A.B.2
Teixeira, A.3
Wong, D.4
Williams, K.J.5
Ahmed, B.6
Ragoussis, J.7
Udalova, I.A.8
Smale, S.T.9
Bulyk, M.L.10
-
41
-
-
66249136447
-
Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis
-
Spencer S.L., Gaudet S., Albeck J.G., Burke J.M., Sorger P.K. Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis. Nature 2009, 459:428-432.
-
(2009)
Nature
, vol.459
, pp. 428-432
-
-
Spencer, S.L.1
Gaudet, S.2
Albeck, J.G.3
Burke, J.M.4
Sorger, P.K.5
-
42
-
-
77954541844
-
Single-cell NF-kappaB dynamics reveal digital activation and analogue information processing
-
Tay S., Hughey J.J., Lee T.K., Lipniacki T., Quake S.R., Covert M.W. Single-cell NF-kappaB dynamics reveal digital activation and analogue information processing. Nature 2010, 466:267-271.
-
(2010)
Nature
, vol.466
, pp. 267-271
-
-
Tay, S.1
Hughey, J.J.2
Lee, T.K.3
Lipniacki, T.4
Quake, S.R.5
Covert, M.W.6
-
43
-
-
0026508987
-
The characterization of the promoter of the gene encoding the p50 subunit of NF-kappa B indicates that it participates in its own regulation
-
Ten R.M., Paya C.V., Israël N., Le Bail O., Mattei M.G., Virelizier J.L., Kourilsky P., Israël A. The characterization of the promoter of the gene encoding the p50 subunit of NF-kappa B indicates that it participates in its own regulation. EMBO J. 1992, 11:195-203.
-
(1992)
EMBO J.
, vol.11
, pp. 195-203
-
-
Ten, R.M.1
Paya, C.V.2
Israël, N.3
Le Bail, O.4
Mattei, M.G.5
Virelizier, J.L.6
Kourilsky, P.7
Israël, A.8
-
44
-
-
26444435364
-
A TNF-induced gene expression program under oscillatory NF-kappaB control
-
Tian B., Nowak D.E., Brasier A.R. A TNF-induced gene expression program under oscillatory NF-kappaB control. BMC Genomics 2005, 6:137.
-
(2005)
BMC Genomics
, vol.6
, pp. 137
-
-
Tian, B.1
Nowak, D.E.2
Brasier, A.R.3
-
45
-
-
20444478655
-
Identification of direct genomic targets downstream of the nuclear factor-kappaB transcription factor mediating tumor necrosis factor signaling
-
Tian B., Nowak D.E., Jamaluddin M., Wang S., Brasier A.R. Identification of direct genomic targets downstream of the nuclear factor-kappaB transcription factor mediating tumor necrosis factor signaling. J.Biol. Chem. 2005, 280:17435-17448.
-
(2005)
J.Biol. Chem.
, vol.280
, pp. 17435-17448
-
-
Tian, B.1
Nowak, D.E.2
Jamaluddin, M.3
Wang, S.4
Brasier, A.R.5
-
46
-
-
0034459681
-
Functional consequences of a polymorphism affecting NF-kappaB p50-p50 binding to the TNF promoter region
-
Udalova I.A., Richardson A., Denys A., Smith C., Ackerman H., Foxwell B., Kwiatkowski D. Functional consequences of a polymorphism affecting NF-kappaB p50-p50 binding to the TNF promoter region. Mol. Cell. Biol. 2000, 20:9113-9119.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 9113-9119
-
-
Udalova, I.A.1
Richardson, A.2
Denys, A.3
Smith, C.4
Ackerman, H.5
Foxwell, B.6
Kwiatkowski, D.7
-
48
-
-
84868093966
-
The transcriptional specificity of NF-κB dimers is coded within the κB DNA response elements
-
Wang V.Y., Huang W., Asagiri M., Spann N., Hoffmann A., Glass C., Ghosh G. The transcriptional specificity of NF-κB dimers is coded within the κB DNA response elements. Cell Rep 2012, 2:824-839.
-
(2012)
Cell Rep
, vol.2
, pp. 824-839
-
-
Wang, V.Y.1
Huang, W.2
Asagiri, M.3
Spann, N.4
Hoffmann, A.5
Glass, C.6
Ghosh, G.7
-
49
-
-
9644268197
-
BCL-3 and NF-kappaB p50 attenuate lipopolysaccharide-induced inflammatory responses in macrophages
-
Wessells J., Baer M., Young H.A., Claudio E., Brown K., Siebenlist U., Johnson P.F. BCL-3 and NF-kappaB p50 attenuate lipopolysaccharide-induced inflammatory responses in macrophages. J.Biol. Chem. 2004, 279:49995-50003.
-
(2004)
J.Biol. Chem.
, vol.279
, pp. 49995-50003
-
-
Wessells, J.1
Baer, M.2
Young, H.A.3
Claudio, E.4
Brown, K.5
Siebenlist, U.6
Johnson, P.F.7
-
50
-
-
0036203419
-
The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1
-
Zhong H., May M.J., Jimi E., Ghosh S. The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1. Mol. Cell 2002, 9:625-636.
-
(2002)
Mol. Cell
, vol.9
, pp. 625-636
-
-
Zhong, H.1
May, M.J.2
Jimi, E.3
Ghosh, S.4
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