Intermolecular epistasis shaped the function and evolution of an ancient transcription factor and its DNA binding sites

eLife

Volumn 4, Issue JUNE2015, 2015, Pages

  Anderson, Dave W ^a   McKeown, Alesia N ^a   Thornton, Joseph W ^b  

^a UNIVERSITY OF OREGON   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; STEROID RECEPTOR; TRANSCRIPTION FACTOR;

AMINO ACID SUBSTITUTION; ANISOTROPY; ARTICLE; BINDING AFFINITY; BINDING SITE; DNA BINDING; DNA RESPONSIVE ELEMENT; DNA SEQUENCE; ENZYME SPECIFICITY; EPISTASIS; FLUORESCENCE ANALYSIS; GENE CONTROL; GENE EXPRESSION; GENE INTERACTION; GENE SEQUENCE; GENETIC VARIABILITY; GENOTYPE; HUMAN; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; MOLECULAR GENETICS; MUTATION; NONHUMAN; PROTEIN PURIFICATION; BIOLOGY; GENETICS; METABOLISM;

BINDING SITES; COMPUTATIONAL BIOLOGY; DNA; EPISTASIS, GENETIC; EVOLUTION, MOLECULAR; RESPONSE ELEMENTS; TRANSCRIPTION FACTORS;

EID: 84937054047     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.07864     Document Type: Article

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