Evolution of DNA specificity in a transcription factor family produced a new gene regulatory module

Cell

Volumn 159, Issue 1, 2014, Pages 58-68

  McKeown, Alesia N ^a   Bridgham, Jamie T ^a   Anderson, Dave W ^a   Murphy, Michael N ^c   Ortlund, Eric A ^c   Thornton, Joseph W ^a,b  

^a UNIVERSITY OF OREGON   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PALINDROMIC DNA; STEROID RECEPTOR; TRANSCRIPTION FACTOR;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; DNA BINDING; DNA SEQUENCE; ESTROGEN RESPONSIVE ELEMENT; FLUORESCENCE POLARIZATION; GENE DUPLICATION; GENE MUTATION; GENE REGULATORY NETWORK; GENE TARGETING; HUMAN; INTERACTIONS WITH DNA; LIGAND BINDING; MOLECULAR EVOLUTION; MOLECULAR RECOGNITION; PHYLOGENETIC TREE; PHYLOGENY; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; THERMODYNAMICS; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DNA RESPONSIVE ELEMENT; GENETICS; METABOLISM; MOLECULAR GENETICS; X RAY CRYSTALLOGRAPHY;

ANIMALS; CRYSTALLOGRAPHY, X-RAY; EVOLUTION, MOLECULAR; GENE REGULATORY NETWORKS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHYLOGENY; RECEPTORS, STEROID; RESPONSE ELEMENTS;

EID: 84907485371     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2014.09.003     Document Type: Article

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