-
1
-
-
77951640946
-
A method and server for predicting damaging missense mutations
-
Adzhubei I.A., et al. A method and server for predicting damaging missense mutations. Nat. Methods 2010, 7:248-249.
-
(2010)
Nat. Methods
, vol.7
, pp. 248-249
-
-
Adzhubei, I.A.1
-
2
-
-
84869453241
-
Adaptive evolution: evaluating empirical support for theoretical predictions
-
Olson-Manning C.F., et al. Adaptive evolution: evaluating empirical support for theoretical predictions. Nat. Rev. Genet. 2012, 13:867-877.
-
(2012)
Nat. Rev. Genet.
, vol.13
, pp. 867-877
-
-
Olson-Manning, C.F.1
-
3
-
-
67651050074
-
Pervasive natural selection in the Drosophila genome?
-
Sella G., et al. Pervasive natural selection in the Drosophila genome?. PLoS Genet. 2009, 5:e1000495.
-
(2009)
PLoS Genet.
, vol.5
, pp. e1000495
-
-
Sella, G.1
-
4
-
-
0000907353
-
The roles of mutation. Inbreeding, crossbreeding, and selection in evolution
-
Genetics Society of America
-
Wright S. The roles of mutation. Inbreeding, crossbreeding, and selection in evolution. Proceedings of the Sixth International Congress of Genetics 1932, 1:356-366. Genetics Society of America.
-
(1932)
Proceedings of the Sixth International Congress of Genetics
, vol.1
, pp. 356-366
-
-
Wright, S.1
-
5
-
-
61349112079
-
From fitness landscapes to seascapes: non-equilibrium dynamics of selection and adaptation
-
Mustonen V., Lässig M. From fitness landscapes to seascapes: non-equilibrium dynamics of selection and adaptation. Trends Genet. 2009, 25:111-119.
-
(2009)
Trends Genet.
, vol.25
, pp. 111-119
-
-
Mustonen, V.1
Lässig, M.2
-
6
-
-
84875703570
-
Analyses of the effects of all ubiquitin point mutants on yeast growth rate
-
Roscoe B.P., et al. Analyses of the effects of all ubiquitin point mutants on yeast growth rate. J. Mol. Biol. 2013, 425:1363-1377.
-
(2013)
J. Mol. Biol.
, vol.425
, pp. 1363-1377
-
-
Roscoe, B.P.1
-
7
-
-
84895727363
-
A Bayesian MCMC approach to assess the complete distribution of fitness effects of new mutations: uncovering the potential for adaptive walks in challenging environments
-
Bank C., et al. A Bayesian MCMC approach to assess the complete distribution of fitness effects of new mutations: uncovering the potential for adaptive walks in challenging environments. Genetics 2014, 196:841-852.
-
(2014)
Genetics
, vol.196
, pp. 841-852
-
-
Bank, C.1
-
8
-
-
84901408859
-
A comprehensive, high-resolution map of a gene's fitness landscape
-
Firnberg E., et al. A comprehensive, high-resolution map of a gene's fitness landscape. Mol. Biol. Evol. 2014, 31:1581-1592.
-
(2014)
Mol. Biol. Evol.
, vol.31
, pp. 1581-1592
-
-
Firnberg, E.1
-
9
-
-
77957963240
-
Rapid construction of empirical RNA fitness landscapes
-
Pitt J.N., Ferré-D'Amaré A.R. Rapid construction of empirical RNA fitness landscapes. Science 2010, 330:376-379.
-
(2010)
Science
, vol.330
, pp. 376-379
-
-
Pitt, J.N.1
Ferré-D'Amaré, A.R.2
-
10
-
-
84880673487
-
Synthetic shuffling and in vitro selection reveal the rugged adaptive fitness landscape of a kinase ribozyme
-
Curtis E.A., Bartel D.P. Synthetic shuffling and in vitro selection reveal the rugged adaptive fitness landscape of a kinase ribozyme. RNA 2013, 19:1116-1128.
-
(2013)
RNA
, vol.19
, pp. 1116-1128
-
-
Curtis, E.A.1
Bartel, D.P.2
-
11
-
-
84883790268
-
Comprehensive experimental fitness landscape and evolutionary network for small RNA
-
Jiménez J.I., et al. Comprehensive experimental fitness landscape and evolutionary network for small RNA. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:14984-14989.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 14984-14989
-
-
Jiménez, J.I.1
-
12
-
-
11244261591
-
In search of the limits of evolution
-
Kondrashov F.A. In search of the limits of evolution. Nat. Genet. 2005, 37:9-10.
-
(2005)
Nat. Genet.
, vol.37
, pp. 9-10
-
-
Kondrashov, F.A.1
-
13
-
-
84860663163
-
Evolutionary insight from whole-genome sequencing of experimentally evolved microbes
-
Dettman J.R., et al. Evolutionary insight from whole-genome sequencing of experimentally evolved microbes. Mol. Ecol. 2012, 21:2058-2077.
-
(2012)
Mol. Ecol.
, vol.21
, pp. 2058-2077
-
-
Dettman, J.R.1
-
14
-
-
84877729488
-
Evolution in microbes
-
Kussell E. Evolution in microbes. Annu. Rev. Biophys. 2013, 42:493-514.
-
(2013)
Annu. Rev. Biophys.
, vol.42
, pp. 493-514
-
-
Kussell, E.1
-
15
-
-
84903291815
-
Microbial evolution. Global epistasis makes adaptation predictable despite sequence-level stochasticity
-
Kryazhimskiy S., et al. Microbial evolution. Global epistasis makes adaptation predictable despite sequence-level stochasticity. Science 2014, 344:1519-1522.
-
(2014)
Science
, vol.344
, pp. 1519-1522
-
-
Kryazhimskiy, S.1
-
16
-
-
54149088214
-
Epistasis - the essential role of gene interactions in the structure and evolution of genetic systems
-
Phillips P.C. Epistasis - the essential role of gene interactions in the structure and evolution of genetic systems. Nat. Rev. Genet. 2008, 9:855-867.
-
(2008)
Nat. Rev. Genet.
, vol.9
, pp. 855-867
-
-
Phillips, P.C.1
-
17
-
-
84874189972
-
Genotype to phenotype: lessons from model organisms for human genetics
-
Lehner B. Genotype to phenotype: lessons from model organisms for human genetics. Nat. Rev. Genet. 2013, 14:168-178.
-
(2013)
Nat. Rev. Genet.
, vol.14
, pp. 168-178
-
-
Lehner, B.1
-
18
-
-
84903374093
-
A structural perspective of compensatory evolution
-
Ivankov D.N., et al. A structural perspective of compensatory evolution. Curr. Opin. Struct. Biol. 2014, 26C:104-112.
-
(2014)
Curr. Opin. Struct. Biol.
, vol.26 C
, pp. 104-112
-
-
Ivankov, D.N.1
-
19
-
-
14844325784
-
Robustness, evolvability, and neutrality
-
Wagner A. Robustness, evolvability, and neutrality. FEBS Lett. 2005, 579:1772-1778.
-
(2005)
FEBS Lett.
, vol.579
, pp. 1772-1778
-
-
Wagner, A.1
-
20
-
-
84858778369
-
Epistasis can lead to fragmented neutral spaces and contingency in evolution
-
Schaper S., et al. Epistasis can lead to fragmented neutral spaces and contingency in evolution. Proc. Biol. Sci. 2012, 279:1777-1783.
-
(2012)
Proc. Biol. Sci.
, vol.279
, pp. 1777-1783
-
-
Schaper, S.1
-
21
-
-
79960642108
-
Molecular mechanisms of epistasis within and between genes
-
Lehner B. Molecular mechanisms of epistasis within and between genes. Trends Genet. 2011, 27:323-331.
-
(2011)
Trends Genet.
, vol.27
, pp. 323-331
-
-
Lehner, B.1
-
22
-
-
80052031934
-
Systems-biology approaches for predicting genomic evolution
-
Papp B., et al. Systems-biology approaches for predicting genomic evolution. Nat. Rev. Genet. 2011, 12:591-602.
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 591-602
-
-
Papp, B.1
-
23
-
-
84866776512
-
Metabolic networks and their evolution
-
Wagner A. Metabolic networks and their evolution. Adv. Exp. Med. Biol. 2012, 751:29-52.
-
(2012)
Adv. Exp. Med. Biol.
, vol.751
, pp. 29-52
-
-
Wagner, A.1
-
24
-
-
84890546613
-
Systems genetics approaches to understand complex traits
-
Civelek M., Lusis A.J. Systems genetics approaches to understand complex traits. Nat. Rev. Genet. 2014, 15:34-48.
-
(2014)
Nat. Rev. Genet.
, vol.15
, pp. 34-48
-
-
Civelek, M.1
Lusis, A.J.2
-
25
-
-
84899452541
-
Cryptic genetic variation: evolution's hidden substrate
-
Paaby A.B., Rockman M.V. Cryptic genetic variation: evolution's hidden substrate. Nat. Rev. Genet. 2014, 15:247-258.
-
(2014)
Nat. Rev. Genet.
, vol.15
, pp. 247-258
-
-
Paaby, A.B.1
Rockman, M.V.2
-
26
-
-
84890562372
-
Epistasis and quantitative traits: using model organisms to study gene-gene interactions
-
Mackay T.F. Epistasis and quantitative traits: using model organisms to study gene-gene interactions. Nat. Rev. Genet. 2014, 15:22-33.
-
(2014)
Nat. Rev. Genet.
, vol.15
, pp. 22-33
-
-
Mackay, T.F.1
-
27
-
-
33846277942
-
The evolution of sex: empirical insights into the roles of epistasis and drift
-
de Visser J.A., Elena S.F. The evolution of sex: empirical insights into the roles of epistasis and drift. Nat. Rev. Genet. 2007, 8:139-149.
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 139-149
-
-
de Visser, J.A.1
Elena, S.F.2
-
29
-
-
0019296687
-
A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences
-
Kimura M. A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences. J. Mol. Evol. 1980, 16:111-120.
-
(1980)
J. Mol. Evol.
, vol.16
, pp. 111-120
-
-
Kimura, M.1
-
31
-
-
0028996002
-
Multiple fitness peaks and epistasis
-
Whitlock M.C., et al. Multiple fitness peaks and epistasis. Annu. Rev. Ecol. Syst. 1995, 26:601-629.
-
(1995)
Annu. Rev. Ecol. Syst.
, vol.26
, pp. 601-629
-
-
Whitlock, M.C.1
-
32
-
-
80855127462
-
The causes of epistasis
-
de Visser J.A., et al. The causes of epistasis. Proc. Biol. Sci. 2011, 278:3617-3624.
-
(2011)
Proc. Biol. Sci.
, vol.278
, pp. 3617-3624
-
-
de Visser, J.A.1
-
33
-
-
84891364264
-
Mutational effects on stability are largely conserved during protein evolution
-
Ashenberg O., et al. Mutational effects on stability are largely conserved during protein evolution. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:21071-21076.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 21071-21076
-
-
Ashenberg, O.1
-
34
-
-
0014935646
-
Natural selection and the concept of a protein space
-
Maynard Smith J. Natural selection and the concept of a protein space. Nature 1970, 225:563-564.
-
(1970)
Nature
, vol.225
, pp. 563-564
-
-
Maynard Smith, J.1
-
35
-
-
0031284943
-
Evolution and speciation on holey adaptive landscapes
-
Gavrilets S. Evolution and speciation on holey adaptive landscapes. Trends Ecol. Evol. 1997, 12:307-312.
-
(1997)
Trends Ecol. Evol.
, vol.12
, pp. 307-312
-
-
Gavrilets, S.1
-
36
-
-
52449148668
-
The role of compensatory neutral mutations in molecular evolution
-
Kimura M. The role of compensatory neutral mutations in molecular evolution. J. Genet. 1985, 64:7-19.
-
(1985)
J. Genet.
, vol.64
, pp. 7-19
-
-
Kimura, M.1
-
37
-
-
84882790991
-
Experiments on the role of deleterious mutations as stepping stones in adaptive evolution
-
Covert A.W., et al. Experiments on the role of deleterious mutations as stepping stones in adaptive evolution. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:E3171-E3178.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. E3171-E3178
-
-
Covert, A.W.1
-
38
-
-
77949423534
-
Compensatory evolution in mitochondrial tRNAs navigates valleys of low fitness
-
Meer M.V., et al. Compensatory evolution in mitochondrial tRNAs navigates valleys of low fitness. Nature 2010, 464:279-282.
-
(2010)
Nature
, vol.464
, pp. 279-282
-
-
Meer, M.V.1
-
39
-
-
0030030533
-
Smoothness within ruggedness: the role of neutrality in adaptation
-
Huynen M.A., et al. Smoothness within ruggedness: the role of neutrality in adaptation. Proc. Natl. Acad. Sci. U.S.A. 1996, 93:397-401.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 397-401
-
-
Huynen, M.A.1
-
40
-
-
0031556932
-
Percolation on the fitness hypercube and the evolution of reproductive isolation
-
Gavrilets S., Gravner J. Percolation on the fitness hypercube and the evolution of reproductive isolation. J. Theor. Biol. 1997, 184:51-64.
-
(1997)
J. Theor. Biol.
, vol.184
, pp. 51-64
-
-
Gavrilets, S.1
Gravner, J.2
-
41
-
-
79958067508
-
Visualizing fitness landscapes
-
McCandlish D.M. Visualizing fitness landscapes. Evolution 2011, 65:1544-1558.
-
(2011)
Evolution
, vol.65
, pp. 1544-1558
-
-
McCandlish, D.M.1
-
42
-
-
84867425613
-
The peaks and geometry of fitness landscapes
-
Crona K., et al. The peaks and geometry of fitness landscapes. J. Theor. Biol. 2013, 317:1-10.
-
(2013)
J. Theor. Biol.
, vol.317
, pp. 1-10
-
-
Crona, K.1
-
43
-
-
0017859453
-
Selection differentials and selection coefficients
-
Milkman R. Selection differentials and selection coefficients. Genetics 1978, 88:391-403.
-
(1978)
Genetics
, vol.88
, pp. 391-403
-
-
Milkman, R.1
-
44
-
-
3142698362
-
Effect of overall phenotypic selection on genetic change at individual loci
-
Kimura M., Crow J.F. Effect of overall phenotypic selection on genetic change at individual loci. Proc. Natl. Acad. Sci. U.S.A. 1978, 75:6168-6171.
-
(1978)
Proc. Natl. Acad. Sci. U.S.A.
, vol.75
, pp. 6168-6171
-
-
Kimura, M.1
Crow, J.F.2
-
45
-
-
21044435697
-
Perspective: sign epistasis and genetic constraint on evolutionary trajectories
-
Weinreich D.M., et al. Perspective: sign epistasis and genetic constraint on evolutionary trajectories. Evolution 2005, 59:1165-1174.
-
(2005)
Evolution
, vol.59
, pp. 1165-1174
-
-
Weinreich, D.M.1
-
46
-
-
0001232092
-
Studies on hybrid sterility. II. Localization of sterility factors in Drosophila pseudoobscura hybrids
-
Dobzhansky T. Studies on hybrid sterility. II. Localization of sterility factors in Drosophila pseudoobscura hybrids. Genetics 1936, 21:113-135.
-
(1936)
Genetics
, vol.21
, pp. 113-135
-
-
Dobzhansky, T.1
-
47
-
-
84979134212
-
Reversibility in evolution considered from the standpoint of genetics
-
Muller H.J. Reversibility in evolution considered from the standpoint of genetics. Biol. Rev. Camb. Philos. Soc. 1939, 14:261-280.
-
(1939)
Biol. Rev. Camb. Philos. Soc.
, vol.14
, pp. 261-280
-
-
Muller, H.J.1
-
48
-
-
0028942011
-
The population genetics of speciation: the evolution of hybrid incompatibilities
-
Orr H.A. The population genetics of speciation: the evolution of hybrid incompatibilities. Genetics 1995, 139:1805-1813.
-
(1995)
Genetics
, vol.139
, pp. 1805-1813
-
-
Orr, H.A.1
-
49
-
-
0037069428
-
Dobzhansky-Muller incompatibilities in protein evolution
-
Kondrashov A.S., et al. Dobzhansky-Muller incompatibilities in protein evolution. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:14878-14883.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 14878-14883
-
-
Kondrashov, A.S.1
-
50
-
-
84889582432
-
Should evolutionary geneticists worry about higher-order epistasis?
-
Weinreich D.M., et al. Should evolutionary geneticists worry about higher-order epistasis?. Curr. Opin. Genet. Dev. 2013, 23:700-707.
-
(2013)
Curr. Opin. Genet. Dev.
, vol.23
, pp. 700-707
-
-
Weinreich, D.M.1
-
52
-
-
84902775598
-
Empirical fitness landscapes and the predictability of evolution
-
de Visser J.A., Krug J. Empirical fitness landscapes and the predictability of evolution. Nat. Rev. Genet. 2014, 15:480-490.
-
(2014)
Nat. Rev. Genet.
, vol.15
, pp. 480-490
-
-
de Visser, J.A.1
Krug, J.2
-
53
-
-
84874460493
-
Quantitative analyses of empirical fitness landscapes
-
Szendro I.G., et al. Quantitative analyses of empirical fitness landscapes. J. Stat. Mech. Theor. Exp. 2013, 1:P01005.
-
(2013)
J. Stat. Mech. Theor. Exp.
, vol.1
, pp. P01005
-
-
Szendro, I.G.1
-
56
-
-
33750174645
-
Epistatic interactions: how strong in disease and evolution?
-
Azevedo L., et al. Epistatic interactions: how strong in disease and evolution?. Trends Genet. 2006, 22:581-585.
-
(2006)
Trends Genet.
, vol.22
, pp. 581-585
-
-
Azevedo, L.1
-
57
-
-
79955423458
-
A systems analysis of mutational effects in HIV-1 protease and reverse transcriptase
-
Hinkley T., et al. A systems analysis of mutational effects in HIV-1 protease and reverse transcriptase. Nat. Genet. 2011, 43:487-489.
-
(2011)
Nat. Genet.
, vol.43
, pp. 487-489
-
-
Hinkley, T.1
-
58
-
-
84868365613
-
The spatial architecture of protein function and adaptation
-
McLaughlin R.N., et al. The spatial architecture of protein function and adaptation. Nature 2012, 491:138-142.
-
(2012)
Nature
, vol.491
, pp. 138-142
-
-
McLaughlin, R.N.1
-
59
-
-
84867781208
-
Epistasis as the primary factor in molecular evolution
-
Breen M.S., et al. Epistasis as the primary factor in molecular evolution. Nature 2012, 490:535-538.
-
(2012)
Nature
, vol.490
, pp. 535-538
-
-
Breen, M.S.1
-
60
-
-
84878410814
-
The role of epistasis in protein evolution
-
McCandlish D.M., et al. The role of epistasis in protein evolution. Nature 2013, 497:E1-E2.
-
(2013)
Nature
, vol.497
, pp. E1-E2
-
-
McCandlish, D.M.1
-
61
-
-
84878383073
-
Reply: the role of epistasis in protein evolution
-
Breen M.S., et al. Reply: the role of epistasis in protein evolution. Nature 2013, 497:E2-E3.
-
(2013)
Nature
, vol.497
, pp. E2-E3
-
-
Breen, M.S.1
-
62
-
-
84880787307
-
Mechanisms of protein sequence divergence and incompatibility
-
Wellner A., et al. Mechanisms of protein sequence divergence and incompatibility. PLoS Genet. 2013, 9:e1003665.
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003665
-
-
Wellner, A.1
-
63
-
-
21044438202
-
The rate of compensatory mutation in the DNA bacteriophage phiX174
-
Poon A., Chao L. The rate of compensatory mutation in the DNA bacteriophage phiX174. Genetics 2005, 170:989-999.
-
(2005)
Genetics
, vol.170
, pp. 989-999
-
-
Poon, A.1
Chao, L.2
-
64
-
-
78751652118
-
Ninety years of Drosophila melanogaster hybrids
-
Barbash D.A. Ninety years of Drosophila melanogaster hybrids. Genetics 2010, 186:1-8.
-
(2010)
Genetics
, vol.186
, pp. 1-8
-
-
Barbash, D.A.1
-
65
-
-
77249093924
-
The molecular evolutionary basis of species formation
-
Presgraves D.C. The molecular evolutionary basis of species formation. Nat. Rev. Genet. 2010, 11:175-180.
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 175-180
-
-
Presgraves, D.C.1
-
66
-
-
80755169477
-
The genetics of hybrid incompatibilities
-
Maheshwari S., Barbash D.A. The genetics of hybrid incompatibilities. Annu. Rev. Genet. 2011, 45:331-355.
-
(2011)
Annu. Rev. Genet.
, vol.45
, pp. 331-355
-
-
Maheshwari, S.1
Barbash, D.A.2
-
67
-
-
77956698823
-
A test of the snowball theory for the rate of evolution of hybrid incompatibilities
-
Matute D.R., et al. A test of the snowball theory for the rate of evolution of hybrid incompatibilities. Science 2010, 329:1518-1521.
-
(2010)
Science
, vol.329
, pp. 1518-1521
-
-
Matute, D.R.1
-
68
-
-
0028146883
-
Epistasis can facilitate the evolution of reproductive isolation by peak shifts: a two-locus two-allele model
-
Wagner A., et al. Epistasis can facilitate the evolution of reproductive isolation by peak shifts: a two-locus two-allele model. Genetics 1994, 138:533-545.
-
(1994)
Genetics
, vol.138
, pp. 533-545
-
-
Wagner, A.1
-
69
-
-
0032558269
-
Rapid parapatric speciation on holey adaptive landscapes
-
Gavrilets S., et al. Rapid parapatric speciation on holey adaptive landscapes. Proc. Biol. Sci. 1998, 265:1483-1489.
-
(1998)
Proc. Biol. Sci.
, vol.265
, pp. 1483-1489
-
-
Gavrilets, S.1
-
70
-
-
84878935899
-
Epistasis among adaptive mutations in deer mouse hemoglobin
-
Natarajan C., et al. Epistasis among adaptive mutations in deer mouse hemoglobin. Science 2013, 340:1324-1327.
-
(2013)
Science
, vol.340
, pp. 1324-1327
-
-
Natarajan, C.1
-
71
-
-
84885671999
-
Accessible mutational trajectories for the evolution of pyrimethamine resistance in the malaria parasite Plasmodium vivax
-
Jiang P.P., et al. Accessible mutational trajectories for the evolution of pyrimethamine resistance in the malaria parasite Plasmodium vivax. J. Mol. Evol. 2013, 77:81-91.
-
(2013)
J. Mol. Evol.
, vol.77
, pp. 81-91
-
-
Jiang, P.P.1
-
72
-
-
84872047294
-
Genetic background affects epistatic interactions between two beneficial mutations
-
Wang Y., et al. Genetic background affects epistatic interactions between two beneficial mutations. Biol. Lett. 2013, 9:20120328.
-
(2013)
Biol. Lett.
, vol.9
, pp. 20120328
-
-
Wang, Y.1
-
73
-
-
84901627198
-
Epistatically interacting substitutions are enriched during adaptive protein evolution
-
Gong L.I., Bloom J.D. Epistatically interacting substitutions are enriched during adaptive protein evolution. PLoS Genet. 2014, 10:e1004328.
-
(2014)
PLoS Genet.
, vol.10
, pp. e1004328
-
-
Gong, L.I.1
Bloom, J.D.2
-
74
-
-
84889598510
-
Genetic incompatibilities are widespread within species
-
Corbett-Detig R.B., et al. Genetic incompatibilities are widespread within species. Nature 2013, 504:135-137.
-
(2013)
Nature
, vol.504
, pp. 135-137
-
-
Corbett-Detig, R.B.1
-
75
-
-
84900302836
-
Detection and replication of epistasis influencing transcription in humans
-
Hemani G., et al. Detection and replication of epistasis influencing transcription in humans. Nature 2014, 508:249-253.
-
(2014)
Nature
, vol.508
, pp. 249-253
-
-
Hemani, G.1
-
76
-
-
33645666942
-
Darwinian evolution can follow only very few mutational paths to fitter proteins
-
Weinreich D.M., et al. Darwinian evolution can follow only very few mutational paths to fitter proteins. Science 2006, 312:111-114.
-
(2006)
Science
, vol.312
, pp. 111-114
-
-
Weinreich, D.M.1
-
77
-
-
70349464621
-
An epistatic ratchet constrains the direction of glucocorticoid receptor evolution
-
Bridgham J.T., et al. An epistatic ratchet constrains the direction of glucocorticoid receptor evolution. Nature 2009, 461:515-519.
-
(2009)
Nature
, vol.461
, pp. 515-519
-
-
Bridgham, J.T.1
-
78
-
-
67749098058
-
Stepwise acquisition of pyrimethamine resistance in the malaria parasite
-
Lozovsky E.R., et al. Stepwise acquisition of pyrimethamine resistance in the malaria parasite. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:12025-12030.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 12025-12030
-
-
Lozovsky, E.R.1
-
79
-
-
78649365006
-
Compensatory mutations restore fitness during the evolution of dihydrofolate reductase
-
Brown K.M., et al. Compensatory mutations restore fitness during the evolution of dihydrofolate reductase. Mol. Biol. Evol. 2010, 27:2682-2690.
-
(2010)
Mol. Biol. Evol.
, vol.27
, pp. 2682-2690
-
-
Brown, K.M.1
-
80
-
-
79953738501
-
Initial mutations direct alternative pathways of protein evolution
-
Salverda M.L., et al. Initial mutations direct alternative pathways of protein evolution. PLoS Genet. 2011, 7:e1001321.
-
(2011)
PLoS Genet.
, vol.7
, pp. e1001321
-
-
Salverda, M.L.1
-
81
-
-
84878427504
-
Experimental interrogation of the path dependence and stochasticity of protein evolution using phage-assisted continuous evolution
-
Dickinson B.C., et al. Experimental interrogation of the path dependence and stochasticity of protein evolution using phage-assisted continuous evolution. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:9007-9012.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 9007-9012
-
-
Dickinson, B.C.1
-
82
-
-
84879064073
-
Stability-mediated epistasis constrains the evolution of an influenza protein
-
Gong L.I., et al. Stability-mediated epistasis constrains the evolution of an influenza protein. Elife 2013, 2:e00631.
-
(2013)
Elife
, vol.2
, pp. e00631
-
-
Gong, L.I.1
-
83
-
-
42249084107
-
Homoplasy in genome-wide analysis of rare amino acid replacements: the molecular-evolutionary basis for Vavilov's law of homologous series
-
Rogozin I.B., et al. Homoplasy in genome-wide analysis of rare amino acid replacements: the molecular-evolutionary basis for Vavilov's law of homologous series. Biol. Direct 2008, 3:7.
-
(2008)
Biol. Direct
, vol.3
, pp. 7
-
-
Rogozin, I.B.1
-
84
-
-
77953718211
-
Sequence space and the ongoing expansion of the protein universe
-
Povolotskaya I.S., Kondrashov F.A. Sequence space and the ongoing expansion of the protein universe. Nature 2010, 465:922-926.
-
(2010)
Nature
, vol.465
, pp. 922-926
-
-
Povolotskaya, I.S.1
Kondrashov, F.A.2
-
85
-
-
84866697042
-
Fitness conferred by replaced amino acids declines with time
-
Naumenko S.A., et al. Fitness conferred by replaced amino acids declines with time. Biol. Lett. 2012, 8:825-828.
-
(2012)
Biol. Lett.
, vol.8
, pp. 825-828
-
-
Naumenko, S.A.1
-
86
-
-
84861422981
-
Amino acid coevolution induces an evolutionary Stokes shift
-
Pollock D.D., et al. Amino acid coevolution induces an evolutionary Stokes shift. Proc. Natl. Acad. Sci. U.S.A. 2012, 109:E1352-E1359.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. E1352-E1359
-
-
Pollock, D.D.1
-
87
-
-
84874768052
-
Estimating the rate of irreversibility in protein evolution
-
Soylemez O., Kondrashov F.A. Estimating the rate of irreversibility in protein evolution. Genome Biol. Evol. 2012, 4:1213-1222.
-
(2012)
Genome Biol. Evol.
, vol.4
, pp. 1213-1222
-
-
Soylemez, O.1
Kondrashov, F.A.2
-
88
-
-
34547769282
-
Mutational reversions during adaptive protein evolution
-
DePristo M.A., et al. Mutational reversions during adaptive protein evolution. Mol. Biol. Evol. 2007, 24:1608-1610.
-
(2007)
Mol. Biol. Evol.
, vol.24
, pp. 1608-1610
-
-
DePristo, M.A.1
-
89
-
-
33646182934
-
An integrated view of protein evolution
-
Pál C., et al. An integrated view of protein evolution. Nat. Rev. Genet. 2006, 7:337-348.
-
(2006)
Nat. Rev. Genet.
, vol.7
, pp. 337-348
-
-
Pál, C.1
-
90
-
-
77649279189
-
Rate of sequence divergence under constant selection
-
Kondrashov A.S., et al. Rate of sequence divergence under constant selection. Biol. Direct 2010, 5:5.
-
(2010)
Biol. Direct
, vol.5
, pp. 5
-
-
Kondrashov, A.S.1
-
91
-
-
0023647382
-
Towards a general theory of adaptive walks on rugged landscapes
-
Kauffman S., Levin S. Towards a general theory of adaptive walks on rugged landscapes. J. Theor. Biol. 1987, 128:11-45.
-
(1987)
J. Theor. Biol.
, vol.128
, pp. 11-45
-
-
Kauffman, S.1
Levin, S.2
-
92
-
-
84883555753
-
On the findability of genotypes
-
McCandlish D.M. On the findability of genotypes. Evolution 2013, 67:2592-2603.
-
(2013)
Evolution
, vol.67
, pp. 2592-2603
-
-
McCandlish, D.M.1
-
93
-
-
83455238341
-
Biophysical and structural considerations for protein sequence evolution
-
Grahnen J.A., et al. Biophysical and structural considerations for protein sequence evolution. BMC Evol. Biol. 2011, 11:361.
-
(2011)
BMC Evol. Biol.
, vol.11
, pp. 361
-
-
Grahnen, J.A.1
-
94
-
-
84861209926
-
Do natural proteins differ from random sequences polypeptides? Natural vs random proteins classification using an evolutionary neural network
-
De Lucrezia D., et al. Do natural proteins differ from random sequences polypeptides? Natural vs random proteins classification using an evolutionary neural network. PLoS ONE 2012, 7:e36634.
-
(2012)
PLoS ONE
, vol.7
, pp. e36634
-
-
De Lucrezia, D.1
-
95
-
-
75849116590
-
A minimal sequence code for switching protein structure and function
-
Alexander P.A., et al. A minimal sequence code for switching protein structure and function. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:21149-21154.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 21149-21154
-
-
Alexander, P.A.1
-
96
-
-
84856043672
-
A mathematical theory of communication
-
623-656
-
Shannon C.E. A mathematical theory of communication. Bell Syst. Tech. J. 1948, 27:379-423. 623-656.
-
(1948)
Bell Syst. Tech. J.
, vol.27
, pp. 379-423
-
-
Shannon, C.E.1
-
97
-
-
37349001288
-
An entropy-based approach for testing genetic epistasis underlying complex diseases
-
Kang G.L., et al. An entropy-based approach for testing genetic epistasis underlying complex diseases. J. Theor. Biol. 2008, 250:362-374.
-
(2008)
J. Theor. Biol.
, vol.250
, pp. 362-374
-
-
Kang, G.L.1
-
98
-
-
58349085338
-
Local connectivity of neutral networks
-
Reidys C.M. Local connectivity of neutral networks. Bull. Math. Biol. 2009, 71:265-290.
-
(2009)
Bull. Math. Biol.
, vol.71
, pp. 265-290
-
-
Reidys, C.M.1
-
99
-
-
0036557854
-
Generalized topological spaces in evolutionary theory and combinatorial chemistry
-
Stadler B.M., Stadler P.F. Generalized topological spaces in evolutionary theory and combinatorial chemistry. J. Chem. Inf. Comput. Sci. 2002, 42:577-585.
-
(2002)
J. Chem. Inf. Comput. Sci.
, vol.42
, pp. 577-585
-
-
Stadler, B.M.1
Stadler, P.F.2
|