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Volumn 10, Issue , 2015, Pages 91-103

Prospects for in vitro myofilament maturation in stem cell-derived cardiac myocytes

Author keywords

Cardiomyopathy; Disease modeling; Engineered heart tissue human pluripotent stem cell derived cardiomyocytes; Maturation; Protein isoforms

Indexed keywords

CALCIUM; CONNECTIN; ISOPROTEIN; MYOSIN HEAVY CHAIN; MYOSIN LIGHT CHAIN; TROPONIN I; TROPONIN T;

EID: 84934960294     PISSN: None     EISSN: 11772719     Source Type: Journal    
DOI: 10.4137/BMIMI.S23912     Document Type: Article
Times cited : (14)

References (140)
  • 1
    • 84908468829 scopus 로고    scopus 로고
    • Human embry­onic stem cells vs human induced pluripotent stem cells for cardiac repair
    • Barad L, Schick R, Zeevi-Levin N, Itskovitz-Eldor J, Binah O. Human embry­onic stem cells vs human induced pluripotent stem cells for cardiac repair. Can J Cardiol. 2014;30(11):1279–87.
    • (2014) Can J Cardiol , vol.30 , Issue.11 , pp. 1279-1287
    • Barad, L.1    Schick, R.2    Zeevi-Levin, N.3    Itskovitz-Eldor, J.4    Binah, O.5
  • 2
    • 84873353816 scopus 로고    scopus 로고
    • Induced pluripotent stem cells in cardiovascu­lar drug discovery
    • Mercola M, Colas A, Willems E. Induced pluripotent stem cells in cardiovascu­lar drug discovery. Circ Res. 2013;112(3):534–48.
    • (2013) Circ Res , vol.112 , Issue.3 , pp. 534-548
    • Mercola, M.1    Colas, A.2    Willems, E.3
  • 3
    • 84897864670 scopus 로고    scopus 로고
    • Modeling inherited cardiac disorders
    • Sallam K, Kodo K, Wu JC. Modeling inherited cardiac disorders. Circ J. 2014;78(4):784–94.
    • (2014) Circ J , vol.78 , Issue.4 , pp. 784-794
    • Sallam, K.1    Kodo, K.2    Wu, J.C.3
  • 4
    • 84899480082 scopus 로고    scopus 로고
    • Human-induced pluripotent stem cell models of inherited cardiomyopathies
    • Karakikes I, Termglinchan V, Wu JC. Human-induced pluripotent stem cell models of inherited cardiomyopathies. Curr Opin Cardiol. 2014;29(3):214–9.
    • (2014) Curr Opin Cardiol , vol.29 , Issue.3 , pp. 214-219
    • Karakikes, I.1    Termglinchan, V.2    Wu, J.C.3
  • 5
    • 84927697611 scopus 로고    scopus 로고
    • Current status of induced pluripo­tent stem cells in cardiac tissue regeneration and engineering
    • Liu Z, Zhou J, Wang H, Zhao M, Wang C. Current status of induced pluripo­tent stem cells in cardiac tissue regeneration and engineering. Regener Medicine Research. 2013;1(1):6.
    • (2013) Regener Medicine Research , vol.1 , Issue.1
    • Liu, Z.1    Zhou, J.2    Wang, H.3    Zhao, M.4    Wang, C.5
  • 6
    • 46749142741 scopus 로고    scopus 로고
    • Thin filament regulation in development
    • In: Solaro RJ, Moss RL, eds., 2002nd ed. Berlin: Springer Science & Business Media
    • Anderson P. Thin filament regulation in development. In: Solaro RJ, Moss RL, eds. Molecular Control Mechanisms in Striated Muscle. 2002nd ed. Berlin: Springer Science & Business Media; 2002:329–77.
    • (2002) Molecular Control Mechanisms in Striated Muscle , pp. 329-377
    • Anderson, P.1
  • 7
    • 0029983126 scopus 로고    scopus 로고
    • Contractile protein phenotypic variation during development
    • Murphy A. Contractile protein phenotypic variation during development. Cardiovasc Res. 1996;31 (suppl 1):E25–33.
    • (1996) Cardiovasc Res , vol.31 , pp. E25-E33
    • Murphy, A.1
  • 8
    • 84900549462 scopus 로고    scopus 로고
    • Automated analysis of contractile force and Ca2+ transients in engineered heart tissue
    • Stoehr A, Neuber C, Baldauf C, et al. Automated analysis of contractile force and Ca2+ transients in engineered heart tissue. Am J Physiol Heart Circ Physiol. 2014;306(9):H1353–63.
    • (2014) Am J Physiol Heart Circ Physiol , vol.306 , Issue.9 , pp. H1353-H1363
    • Stoehr, A.1    Neuber, C.2    Baldauf, C.3
  • 9
    • 84904753518 scopus 로고    scopus 로고
    • Functional improvement and mat­uration of rat and human engineered heart tissue by chronic electrical stimula­tion
    • Hirt MN, Boeddinghaus J, Mitchell A, et al. Functional improvement and mat­uration of rat and human engineered heart tissue by chronic electrical stimula­tion. J Mol Cell Cardiol. 2014;74:151–61.
    • (2014) J Mol Cell Cardiol , vol.74 , pp. 151-161
    • Hirt, M.N.1    Boeddinghaus, J.2    Mitchell, A.3
  • 10
    • 84877794737 scopus 로고    scopus 로고
    • Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes
    • Zhang D, Shadrin IY, Lam J, Xian H-Q, Snodgrass HR, Bursac N. Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes. Biomaterials. 2013;34(23):5813–20.
    • (2013) Biomaterials , vol.34 , Issue.23 , pp. 5813-5820
    • Zhang, D.1    Shadrin, I.Y.2    Lam, J.3    Xian, H.-Q.4    Snodgrass, H.R.5    Bursac, N.6
  • 11
    • 84897066639 scopus 로고    scopus 로고
    • Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium
    • Turnbull IC, Karakikes I, Serrao GW, et al. Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium. FASEB J. 2014;28(2):644–54.
    • (2014) FASEB J , vol.28 , Issue.2 , pp. 644-654
    • Turnbull, I.C.1    Karakikes, I.2    Serrao, G.W.3
  • 12
    • 80255131450 scopus 로고    scopus 로고
    • Terminal differentiation, advanced orga­notypic maturation, and modeling of hypertrophic growth in engineered heart tissue
    • Tiburcy M, Didié M, Boy O, et al. Terminal differentiation, advanced orga­notypic maturation, and modeling of hypertrophic growth in engineered heart tissue. Circ Res. 2011;109(10):1105–14.
    • (2011) Circ Res , vol.109 , Issue.10 , pp. 1105-1114
    • Tiburcy, M.1    Didié, M.2    Boy, O.3
  • 13
    • 84878990884 scopus 로고    scopus 로고
    • Induced pluripotent stem cell-derived cardiac progenitors differentiate to cardio­myocytes and form biosynthetic tissues
    • Christoforou N, Liau B, Chakraborty S, Chellapan M, Bursac N, Leong KW. Induced pluripotent stem cell-derived cardiac progenitors differentiate to cardio­myocytes and form biosynthetic tissues. PLoS One. 2013;8(6):e65963.
    • (2013) Plos One , vol.8 , Issue.6
    • Christoforou, N.1    Liau, B.2    Chakraborty, S.3    Chellapan, M.4    Bursac, N.5    Leong, K.W.6
  • 14
    • 84881480907 scopus 로고    scopus 로고
    • Biowire: A platform for matura­tion of human pluripotent stem cell-derived cardiomyocytes
    • Nunes S, Miklas J, Liu J, Aschar-Sobbi R. Biowire: a platform for matura­tion of human pluripotent stem cell-derived cardiomyocytes. Nat Methods. 2013;10(8):781–7.
    • (2013) Nat Methods , vol.10 , Issue.8 , pp. 781-787
    • Nunes, S.1    Miklas, J.2    Liu, J.3    Aschar-Sobbi, R.4
  • 15
    • 84876322089 scopus 로고    scopus 로고
    • Mechanism-based facilitated matu­ration of human pluripotent stem cell-derived cardiomyocytes
    • Lieu DK, Fu JD, Chiamvimonvat N, et al. Mechanism-based facilitated matu­ration of human pluripotent stem cell-derived cardiomyocytes. Circ Arrhythm Electrophysiol. 2013;6(1):191–201.
    • (2013) Circ Arrhythm Electrophysiol , vol.6 , Issue.1 , pp. 191-201
    • Lieu, D.K.1    Fu, J.D.2    Chiamvimonvat, N.3
  • 16
    • 84876529379 scopus 로고    scopus 로고
    • Murine and human pluripotent stem cell-derived cardiac bodies form contractile myocardial tissue in vitro
    • Kensah G, Roa Lara A, Dahlmann J, et al. Murine and human pluripotent stem cell-derived cardiac bodies form contractile myocardial tissue in vitro. Eur Heart J. 2013;34(15):1134–46.
    • (2013) Eur Heart J , vol.34 , Issue.15 , pp. 1134-1146
    • Kensah, G.1    Roa Lara, A.2    Dahlmann, J.3
  • 17
    • 84872026086 scopus 로고    scopus 로고
    • Abnormal calcium handling proper­ties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells
    • Lan F, Lee A, Liang P, Sanchez-Freire V. Abnormal calcium handling proper­ties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells. Cell Stem Cell. 2013;12(1):101–13.
    • (2013) Cell Stem Cell , vol.12 , Issue.1 , pp. 101-113
    • Lan, F.1    Lee, A.2    Liang, P.3    Sanchez-Freire, V.4
  • 18
    • 84860156650 scopus 로고    scopus 로고
    • Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy
    • Sun N, Yazawa M, Liu J, et al. Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy. Sci Transl Med. 2012;4(130):1–14.
    • (2012) Sci Transl Med , vol.4 , Issue.130 , pp. 1-14
    • Sun, N.1    Yazawa, M.2    Liu, J.3
  • 19
    • 84913546568 scopus 로고    scopus 로고
    • Applications of human-induced pluripotent stem cells in the investigation of inherited cardiomyopathy
    • Zhao Q, Cai H, Zhan Y, Li B, Hu S, Sun N. Applications of human-induced pluripotent stem cells in the investigation of inherited cardiomyopathy. Int J Car­diol. 2014;177(2):604–6.
    • (2014) Int J Car­diol , vol.177 , Issue.2 , pp. 604-606
    • Zhao, Q.1    Cai, H.2    Zhan, Y.3    Li, B.4    Hu, S.5    Sun, N.6
  • 20
    • 84894460947 scopus 로고    scopus 로고
    • A cut above the rest: Targeted genome editing technologies in human pluripotent stem cells
    • Li M, Suzuki K, Kim NY, Liu G-H, Izpisua Belmonte JC. A cut above the rest: targeted genome editing technologies in human pluripotent stem cells. J Biol Chem. 2014;289(8):4594–9.
    • (2014) J Biol Chem , vol.289 , Issue.8 , pp. 4594-4599
    • Li, M.1    Suzuki, K.2    Kim, N.Y.3    Liu, G.-H.4    Izpisua Belmonte, J.C.5
  • 21
    • 84892415382 scopus 로고    scopus 로고
    • Modeling of arrhythmogenic right ventricular cardiomyopathy with human induced pluripotent stem cells
    • Caspi O, Huber I, Gepstein A, et al. Modeling of arrhythmogenic right ventricular cardiomyopathy with human induced pluripotent stem cells. Circ Cardiovasc Genet. 2013;6(6):557–68.
    • (2013) Circ Cardiovasc Genet , vol.6 , Issue.6 , pp. 557-568
    • Caspi, O.1    Huber, I.2    Gepstein, A.3
  • 22
    • 84876522952 scopus 로고    scopus 로고
    • Generation of patient-specific induced pluripotent stem cell-derived cardiomyocytes as a cellular model of arrhythmogenic right ventricular cardiomyopathy
    • Ma D, Wei H, Lu J, et al. Generation of patient-specific induced pluripotent stem cell-derived cardiomyocytes as a cellular model of arrhythmogenic right ventricular cardiomyopathy. Eur Heart J. 2013;34(15):1122–33.
    • (2013) Eur Heart J , vol.34 , Issue.15 , pp. 1122-1133
    • Ma, D.1    Wei, H.2    Lu, J.3
  • 23
    • 84874741888 scopus 로고    scopus 로고
    • Studying arrhythmogenic right ventricular dyspla­sia with patient-specific iPSCs
    • Kim C, Wong J, Wen J, et al. Studying arrhythmogenic right ventricular dyspla­sia with patient-specific iPSCs. Nature. 2013;494(7435):105–10.
    • (2013) Nature , vol.494 , Issue.7435 , pp. 105-110
    • Kim, C.1    Wong, J.2    Wen, J.3
  • 24
    • 83755195408 scopus 로고    scopus 로고
    • Cellular physiology biochemistry and biochemis­try in vitro modeling of ryanodine receptor 2 dysfunction using human induced pluripotent stem cells
    • Fatima A, Xu G, Shao K, et al. Cellular physiology biochemistry and biochemis­try in vitro modeling of ryanodine receptor 2 dysfunction using human induced pluripotent stem cells. Cell Physiol Biochem. 2011;28:579–92.
    • (2011) Cell Physiol Biochem , vol.28 , pp. 579-592
    • Fatima, A.1    Xu, G.2    Shao, K.3
  • 25
    • 84858129398 scopus 로고    scopus 로고
    • Dantrolene rescues arrhyth­mogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia
    • Jung CB, Moretti A, Mederos y Schnitzler M, et al. Dantrolene rescues arrhyth­mogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia. EMBO Mol Med. 2012;4(3):180–91.
    • (2012) EMBO Mol Med , vol.4 , Issue.3 , pp. 180-191
    • Jung, C.B.1    Moretti, A.2    Mederos Y Schnitzler, M.3
  • 26
    • 84857547828 scopus 로고    scopus 로고
    • Cardiomyocytes generated from CPVTD307H patients are arrhythmogenic in response to β-adrenergic stimula­tion
    • Novak A, Barad L, Zeevi-Levin N, et al. Cardiomyocytes generated from CPVTD307H patients are arrhythmogenic in response to β-adrenergic stimula­tion. J Cell Mol Med. 2012;16(3):468–82.
    • (2012) J Cell Mol Med , vol.16 , Issue.3 , pp. 468-482
    • Novak, A.1    Barad, L.2    Zeevi-Levin, N.3
  • 27
    • 84907587769 scopus 로고    scopus 로고
    • RNA expression profiling of human iPSC-derived cardiomyocytes in a cardiac hypertrophy model
    • Aggarwal P, Turner A, Matter A, et al. RNA expression profiling of human iPSC-derived cardiomyocytes in a cardiac hypertrophy model. PLoS One. 2014;9(9):e108051.
    • (2014) Plos One , vol.9 , Issue.9
    • Aggarwal, P.1    Turner, A.2    Matter, A.3
  • 28
    • 84885133772 scopus 로고    scopus 로고
    • Exon skipping and gene transfer restore dystro­phin expression in hiPSC-cardiomyocytes harbouring DMD mutations
    • Dick E, Kalra S, Anderson D. Exon skipping and gene transfer restore dystro­phin expression in hiPSC-cardiomyocytes harbouring DMD mutations. Stem Cells Dev. 2013;22(20):2714–24.
    • (2013) Stem Cells Dev , vol.22 , Issue.20 , pp. 2714-2724
    • Dick, E.1    Kalra, S.2    Erson, D.3
  • 29
    • 84875276852 scopus 로고    scopus 로고
    • Patient-specific induced-pluripotent stem cells-derived cardiomyocytes recapitulate the pathogenic phenotypes of dilated cardi­omyopathy due to a novel DES mutation identified by whole exome sequencing
    • Tse HF, Ho JC, Choi SW, et al. Patient-specific induced-pluripotent stem cells-derived cardiomyocytes recapitulate the pathogenic phenotypes of dilated cardi­omyopathy due to a novel DES mutation identified by whole exome sequencing. Hum Mol Genet. 2013;22(7):1395–403.
    • (2013) Hum Mol Genet , vol.22 , Issue.7 , pp. 1395-1403
    • Tse, H.F.1    Ho, J.C.2    Choi, S.W.3
  • 30
    • 84905719998 scopus 로고    scopus 로고
    • Modeling of Friedreich ataxia-related iron overloading cardiomyopathy using patient-specific-induced pluripotent stem cells
    • Lee YK, Ho PW, Schick R, et al. Modeling of Friedreich ataxia-related iron overloading cardiomyopathy using patient-specific-induced pluripotent stem cells. Pflugers Arch. 2014;466(9):1831–44.
    • (2014) Pflugers Arch , vol.466 , Issue.9 , pp. 1831-1844
    • Lee, Y.K.1    Ho, P.W.2    Schick, R.3
  • 31
    • 84904608539 scopus 로고    scopus 로고
    • Directed differentiation of patient-specific induced pluripotent stem cells identifies the transcriptional repression and epigenetic modification of NKX2–5, HAND1, and NOTCH1 in hypoplas­tic left heart syndrome
    • Kobayashi J, Yoshida M, Tarui S, et al. Directed differentiation of patient-specific induced pluripotent stem cells identifies the transcriptional repression and epigenetic modification of NKX2–5, HAND1, and NOTCH1 in hypoplas­tic left heart syndrome. PLoS One. 2014;9(7):e102796.
    • (2014) Plos One , vol.9 , Issue.7
    • Kobayashi, J.1    Yoshida, M.2    Tarui, S.3
  • 32
    • 84918553552 scopus 로고    scopus 로고
    • Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: Disease mechanisms and pharmacological rescue
    • Zhang M, D’Aniello C, Verkerk AO, et al. Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue. Proc Natl Acad Sci U S A. 2014;111(50):E5383–92.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , Issue.50 , pp. E5383-E5392
    • Zhang, M.1    D’Aniello, C.2    Verkerk, A.O.3
  • 33
    • 77953443251 scopus 로고    scopus 로고
    • Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
    • Carvajal-Vergara X, Sevilla A, D’Souza SL, et al. Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature. 2010;465(7299):808–12.
    • (2010) Nature , vol.465 , Issue.7299 , pp. 808-812
    • Carvajal-Vergara, X.1    Sevilla, A.2    D’Souza, S.L.3
  • 34
    • 79952446402 scopus 로고    scopus 로고
    • Modelling the long QT syndrome with induced pluripotent stem cells
    • Itzhaki I, Maizels L, Huber I, et al. Modelling the long QT syndrome with induced pluripotent stem cells. Nature. 2011;471(7337):225–9.
    • (2011) Nature , vol.471 , Issue.7337 , pp. 225-229
    • Itzhaki, I.1    Maizels, L.2    Huber, I.3
  • 35
    • 77957729169 scopus 로고    scopus 로고
    • Patient-specific induced pluripotent stem-cell models for long-QT syndrome
    • Moretti A, Bellin M, Welling A. Patient-specific induced pluripotent stem-cell models for long-QT syndrome. N Engl J Med. 2010;363(15):1397–409.
    • (2010) N Engl J Med , vol.363 , Issue.15 , pp. 1397-1409
    • Moretti, A.1    Bellin, M.2    Welling, A.3
  • 36
    • 79954523845 scopus 로고    scopus 로고
    • Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syn­drome type 2 mutation
    • Matsa E, Rajamohan D, Dick E, et al. Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syn­drome type 2 mutation. Eur Heart J. 2011;32(8):952–62.
    • (2011) Eur Heart J , vol.32 , Issue.8 , pp. 952-962
    • Matsa, E.1    Rajamohan, D.2    Dick, E.3
  • 37
    • 79952438377 scopus 로고    scopus 로고
    • Using induced pluripotent stem cells to investi­gate cardiac phenotypes in Timothy syndrome
    • Yazawa M, Hsueh B, Jia X, et al. Using induced pluripotent stem cells to investi­gate cardiac phenotypes in Timothy syndrome. Nature. 2011;471(7337):230–4.
    • (2011) Nature , vol.471 , Issue.7337 , pp. 230-234
    • Yazawa, M.1    Hsueh, B.2    Jia, X.3
  • 38
    • 84926624275 scopus 로고    scopus 로고
    • Modeling sarcomeric cardiomyo­pathies in the dish – from human heart samples to iPSC cardiomyocytes
    • Eschenhagen T, Mummery C, Knollmann B. Modeling sarcomeric cardiomyo­pathies in the dish – from human heart samples to iPSC cardiomyocytes. Cardio­vasc Res. 2015;105(4):424–38.
    • (2015) Cardio­vasc Res , vol.105 , Issue.4 , pp. 424-438
    • Eschenhagen, T.1    Mummery, C.2    Knollmann, B.3
  • 39
    • 0028026747 scopus 로고
    • Transition in cardiac contractile sensitivity to calcium during the in vitro differentiation of mouse embryonic stem cells
    • Metzger J, Lin W, Samuelson L. Transition in cardiac contractile sensitivity to calcium during the in vitro differentiation of mouse embryonic stem cells. J Cell Biol. 1994;126(3):701–11.
    • (1994) J Cell Biol , vol.126 , Issue.3 , pp. 701-711
    • Metzger, J.1    Lin, W.2    Samuelson, L.3
  • 40
    • 84876570848 scopus 로고    scopus 로고
    • Concise review: Maturation phases of human pluripotent stem cell-derived cardiomyocytes
    • Robertson C, Tran DD, George SC. Concise review: maturation phases of human pluripotent stem cell-derived cardiomyocytes. Stem Cells. 2013;31(5):829–37.
    • (2013) Stem Cells , vol.31 , Issue.5 , pp. 829-837
    • Robertson, C.1    Tran, D.D.2    George, S.C.3
  • 41
    • 84894160639 scopus 로고    scopus 로고
    • Engineering adolescence: Maturation of human pluripotent stem cell-derived cardiomyocytes
    • Yang X, Pabon L, Murry CE. Engineering adolescence: maturation of human pluripotent stem cell-derived cardiomyocytes. Circ Res. 2014;114(3):511–23.
    • (2014) Circ Res , vol.114 , Issue.3 , pp. 511-523
    • Yang, X.1    Pabon, L.2    Murry, C.E.3
  • 42
    • 55649098531 scopus 로고    scopus 로고
    • Transcriptional and functional pro­filing of human embryonic stem cell-derived cardiomyocytes
    • Cao F, Wagner RA, Wilson KD, et al. Transcriptional and functional pro­filing of human embryonic stem cell-derived cardiomyocytes. PLoS One. 2008;3(10):e3474.
    • (2008) Plos One , vol.3 , Issue.10
    • Cao, F.1    Wagner, R.A.2    Wilson, K.D.3
  • 43
    • 70349868345 scopus 로고    scopus 로고
    • Global expression profile of highly enriched cardiomyocytes derived from human embryonic stem cells
    • Xu XQ, Soo SY, Sun W, Zweigerdt R. Global expression profile of highly enriched cardiomyocytes derived from human embryonic stem cells. Stem Cells. 2009;27:2163–74.
    • (2009) Stem Cells , vol.27 , pp. 2163-2174
    • Xu, X.Q.1    Soo, S.Y.2    Sun, W.3    Zweigerdt, R.4
  • 44
    • 35748931742 scopus 로고    scopus 로고
    • Functional and developmental proper­ties of human embryonic stem cells-derived cardiomyocytes
    • Binah O, Dolnikov K, Sadan O, et al. Functional and developmental proper­ties of human embryonic stem cells-derived cardiomyocytes. J Electrocardiol. 2007;40(6 suppl):S192–6.
    • (2007) J Electrocardiol , vol.40 , Issue.6 , pp. S192-S196
    • Binah, O.1    Dolnikov, K.2    Sadan, O.3
  • 45
    • 33746890218 scopus 로고    scopus 로고
    • Functional properties of human embryonic stem cell-derived cardiomyocytes: Intracellular Ca2+ handling and the role of sarcoplasmic reticulum in the contraction
    • Dolnikov K, Shilkrut M, Zeevi-Levin N, et al. Functional properties of human embryonic stem cell-derived cardiomyocytes: intracellular Ca2+ handling and the role of sarcoplasmic reticulum in the contraction. Stem Cells. 2006;24:236–45.
    • (2006) Stem Cells , vol.24 , pp. 236-245
    • Dolnikov, K.1    Shilkrut, M.2    Zeevi-Levin, N.3
  • 46
    • 84981713746 scopus 로고    scopus 로고
    • Crucial role of the sarcoplasmic reticulum in the developmental regulation of Ca2+ transients and contraction in cardiomyocytes derived from embryonic stem cells
    • Fu JD, Li J, Tweedie D, et al. Crucial role of the sarcoplasmic reticulum in the developmental regulation of Ca2+ transients and contraction in cardiomyocytes derived from embryonic stem cells. FASEB J. 2006;21:1–21.
    • (2006) FASEB J , vol.21 , pp. 1-21
    • Fu, J.D.1    Li, J.2    Tweedie, D.3
  • 47
    • 67650022307 scopus 로고    scopus 로고
    • Absence of transverse tubules contributes to non-uniform Ca(2+) wavefronts in mouse and human embryonic stem cell-derived cardiomyocytes
    • Lieu DK, Liu J, Siu CW, et al. Absence of transverse tubules contributes to non-uniform Ca(2+) wavefronts in mouse and human embryonic stem cell-derived cardiomyocytes. Stem Cells Dev. 2009;18(10):1493–500.
    • (2009) Stem Cells Dev , vol.18 , Issue.10 , pp. 1493-1500
    • Lieu, D.K.1    Liu, J.2    Siu, C.W.3
  • 48
    • 0037049977 scopus 로고    scopus 로고
    • Cardiac excitation-contraction coupling
    • Bers D. Cardiac excitation-contraction coupling. Nature. 2002;415(6868):198–205.
    • (2002) Nature , vol.415 , Issue.6868 , pp. 198-205
    • Bers, D.1
  • 49
    • 84860015582 scopus 로고    scopus 로고
    • Ca2+ channel activators reveal differential L-type Ca2+ channel pharmacology between native and stem cell-derived cardio­myocytes
    • Kang J, Chen X, Ji J, Lei Q, Rampe D. Ca2+ channel activators reveal differential L-type Ca2+ channel pharmacology between native and stem cell-derived cardio­myocytes. J Pharmacol Exp Ther. 2012;341(2):510–7.
    • (2012) J Pharmacol Exp Ther , vol.341 , Issue.2 , pp. 510-517
    • Kang, J.1    Chen, X.2    Ji, J.3    Lei, Q.4    Rampe, D.5
  • 50
    • 82355168775 scopus 로고    scopus 로고
    • Calcium homeostasis in human induced pluri­potent stem cell-derived cardiomyocytes
    • Lee YK, Ng KM, Lai WH, et al. Calcium homeostasis in human induced pluri­potent stem cell-derived cardiomyocytes. Stem Cell Rev. 2011;7(4):976–86.
    • (2011) Stem Cell Rev , vol.7 , Issue.4 , pp. 976-986
    • Lee, Y.K.1    Ng, K.M.2    Lai, W.H.3
  • 51
    • 54249093380 scopus 로고    scopus 로고
    • Human embryonic stem cells for cardiomyogen­esis
    • Habib M, Caspi O, Gepstein L. Human embryonic stem cells for cardiomyogen­esis. J Mol Cell Cardiol. 2008;45(4):462–74.
    • (2008) J Mol Cell Cardiol , vol.45 , Issue.4 , pp. 462-474
    • Habib, M.1    Caspi, O.2    Gepstein, L.3
  • 52
    • 74049156859 scopus 로고    scopus 로고
    • Nongenetic method for purifying stem cell-derived cardiomyocytes
    • Hattori F, Chen H, Yamashita H, et al. Nongenetic method for purifying stem cell-derived cardiomyocytes. Nat Methods. 2010;7(1):61–6.
    • (2010) Nat Methods , vol.7 , Issue.1 , pp. 61-66
    • Hattori, F.1    Chen, H.2    Yamashita, H.3
  • 53
    • 84859641526 scopus 로고    scopus 로고
    • Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG
    • Jonsson MK, Vos MA, Mirams GR, et al. Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG. J Mol Cell Cardiol. 2012;52(5):998–1008.
    • (2012) J Mol Cell Cardiol , vol.52 , Issue.5 , pp. 998-1008
    • Jonsson, M.K.1    Vos, M.A.2    Mirams, G.R.3
  • 54
    • 84988599499 scopus 로고    scopus 로고
    • Physical developmental cues for the maturation of human pluripotent stem cell-derived cardiomyocytes
    • Zhu R, Blazeski A, Poon E, Costa K. Physical developmental cues for the maturation of human pluripotent stem cell-derived cardiomyocytes. Stem Cell Res Ther. 2014;5(117):1–18.
    • (2014) Stem Cell Res Ther , vol.5 , Issue.117 , pp. 1-18
    • Zhu, R.1    Blazeski, A.2    Poon, E.3    Costa, K.4
  • 55
    • 84900335420 scopus 로고    scopus 로고
    • Tri-iodo-l-thyronine promotes the matu­ration of human cardiomyocytes-derived from induced pluripotent stem cells
    • Yang X, Rodriguez M, Pabon L, et al. Tri-iodo-l-thyronine promotes the matu­ration of human cardiomyocytes-derived from induced pluripotent stem cells. J Mol Cell Cardiol. 2014;72:296–304.
    • (2014) J Mol Cell Cardiol , vol.72 , pp. 296-304
    • Yang, X.1    Rodriguez, M.2    Pabon, L.3
  • 56
    • 84880227000 scopus 로고    scopus 로고
    • Structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells
    • Lundy SD, Zhu W-Z, Regnier M, Laflamme MA. Structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells. Stem Cells Dev. 2013;22(14):1991–2002.
    • (2013) Stem Cells Dev , vol.22 , Issue.14 , pp. 1991-2002
    • Lundy, S.D.1    Zhu, W.-Z.2    Regnier, M.3    Laflamme, M.A.4
  • 57
    • 84904253318 scopus 로고    scopus 로고
    • Use of flow, electrical, and mechani­cal stimulation to promote engineering of striated muscles
    • Rangarajan S, Madden L, Bursac N. Use of flow, electrical, and mechani­cal stimulation to promote engineering of striated muscles. Ann Biomed Eng. 2014;42(7):1391–405.
    • (2014) Ann Biomed Eng , vol.42 , Issue.7 , pp. 1391-1405
    • Rangarajan, S.1    Madden, L.2    Bursac, N.3
  • 58
    • 34547592530 scopus 로고    scopus 로고
    • Extracellular matrix, mechanotransduction and struc­tural hierarchies in heart tissue engineering
    • Parker KK, Ingber DE. Extracellular matrix, mechanotransduction and struc­tural hierarchies in heart tissue engineering. Philos Trans R Soc Lond B Biol Sci. 2007;362(1484):1267–79.
    • (2007) Philos Trans R Soc Lond B Biol Sci , vol.362 , Issue.1484 , pp. 1267-1279
    • Parker, K.K.1    Ingber, D.E.2
  • 59
    • 80054783465 scopus 로고    scopus 로고
    • Human engineered heart tissue as a versatile tool in basic research and preclinical toxicology
    • Schaaf S, Shibamiya A, Mewe M, et al. Human engineered heart tissue as a versatile tool in basic research and preclinical toxicology. PLoS One. 2011;6(10):e26397.
    • (2011) Plos One , vol.6 , Issue.10
    • Schaaf, S.1    Shibamiya, A.2    Mewe, M.3
  • 60
    • 84895473350 scopus 로고    scopus 로고
    • Cardiac tissue engineering: State of the art
    • Hirt MN, Hansen A, Eschenhagen T. Cardiac tissue engineering: state of the art. Circ Res. 2014;114(2):354–67.
    • (2014) Circ Res , vol.114 , Issue.2 , pp. 354-367
    • Hirt, M.N.1    Hansen, A.2    Eschenhagen, T.3
  • 61
    • 84868236781 scopus 로고    scopus 로고
    • Cardiac differentiation of human embryonic stem cells and their assembly into engineered heart muscle
    • Chapter 23:23.8.1–21
    • Soong PL, Tiburcy M, Zimmermann W-H. Cardiac differentiation of human embryonic stem cells and their assembly into engineered heart muscle. Curr Protoc Cell Biol. 2012;Chapter 23:23.8.1–21.
    • (2012) Curr Protoc Cell Biol
    • Soong, P.L.1    Tiburcy, M.2    Zimmermann, W.-H.3
  • 62
    • 79960023610 scopus 로고    scopus 로고
    • Growth of engineered human myocardium with mechanical loading and vascular coculture
    • Tulloch NL, Muskheli V, Razumova MV, et al. Growth of engineered human myocardium with mechanical loading and vascular coculture. Circ Res. 2011;109(1):47–59.
    • (2011) Circ Res , vol.109 , Issue.1 , pp. 47-59
    • Tulloch, N.L.1    Muskheli, V.2    Razumova, M.V.3
  • 63
    • 84901218348 scopus 로고    scopus 로고
    • Mimicking isovolumic contraction with combined elec­tromechanical stimulation improves the development of engineered cardiac con­structs
    • Morgan KY, Black LD. Mimicking isovolumic contraction with combined elec­tromechanical stimulation improves the development of engineered cardiac con­structs. Tissue Eng Part A. 2014;20(11):1654–67.
    • (2014) Tissue Eng Part A , vol.20 , Issue.11 , pp. 1654-1667
    • Morgan, K.Y.1    Black, L.D.2
  • 64
    • 0026560211 scopus 로고
    • Altered myocardial force-frequency relation in human heart failure
    • Mulieri L, Hasenfuss G, Leavitt B. Altered myocardial force-frequency relation in human heart failure. Circulation. 1992;85:1743–51.
    • (1992) Circulation , vol.85 , pp. 1743-1751
    • Mulieri, L.1    Hasenfuss, G.2    Leavitt, B.3
  • 65
    • 84892369440 scopus 로고    scopus 로고
    • Small and large animal models in cardiac contrac­tion research: Advantages and disadvantages
    • Milani-Nejad N, Janssen PML. Small and large animal models in cardiac contrac­tion research: advantages and disadvantages. Pharmacol Ther. 2014;141(3):235–49.
    • (2014) Pharmacol Ther , vol.141 , Issue.3 , pp. 235-249
    • Milani-Nejad, N.1    Janssen, P.2
  • 66
    • 65349152532 scopus 로고    scopus 로고
    • Force frequency relationship of the human ventricle increases during early postnatal development
    • Wiegerinck R, Cojoc A, Zeidenweber C. Force frequency relationship of the human ventricle increases during early postnatal development. Pediatr Res. 2009;65(4):414–9.
    • (2009) Pediatr Res , vol.65 , Issue.4 , pp. 414-419
    • Wiegerinck, R.1    Cojoc, A.2    Zeidenweber, C.3
  • 67
    • 0021916285 scopus 로고
    • The economy of isometric force development, myosin isoenzyme pattern and myo­fibrillar ATPase activity in normal and hypothyroid rat myocardium
    • Holubarsch C, Goulette R, Litten R, Martin B, Mulieri L, Alpert N. The economy of isometric force development, myosin isoenzyme pattern and myo­fibrillar ATPase activity in normal and hypothyroid rat myocardium. Circ Res. 1985;56:78–86.
    • (1985) Circ Res , vol.56 , pp. 78-86
    • Holubarsch, C.1    Goulette, R.2    Litten, R.3    Martin, B.4    Mulieri, L.5    Alpert, N.6
  • 68
    • 0024785576 scopus 로고
    • Full-length rat alpha and beta cardiac myosin heavy chain sequences: Comparisons suggest a molecular basis for functional differences
    • McNally E, Kraft R. Full-length rat alpha and beta cardiac myosin heavy chain sequences: comparisons suggest a molecular basis for functional differences. J Mol Biol. 1989;210:665–71.
    • (1989) J Mol Biol , vol.210 , pp. 665-671
    • McNally, E.1    Kraft, R.2
  • 69
    • 0024672199 scopus 로고
    • Characterization of human cardiac myosin heavy chain genes
    • Yamauchi-Takihara K. Characterization of human cardiac myosin heavy chain genes. Proc Natl Acad Sci U S A. 1989;86(5):3504–8.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , Issue.5 , pp. 3504-3508
    • Yamauchi-Takihara, K.1
  • 70
    • 0035862845 scopus 로고    scopus 로고
    • Postnatal myosin heavy chain isoform expression in normal mice and mice null for IIb or IId myosin heavy chains
    • Allen DL, Leinwand LA. Postnatal myosin heavy chain isoform expression in normal mice and mice null for IIb or IId myosin heavy chains. Dev Biol. 2001;229(2):383–95.
    • (2001) Dev Biol , vol.229 , Issue.2 , pp. 383-395
    • Allen, D.L.1    Leinwand, L.A.2
  • 71
    • 0030685743 scopus 로고    scopus 로고
    • Changes in gene expression in the intact human heart. Downregulation of alpha-myosin heavy chain in hypertro­phied, failing ventricular myocardium
    • Lowes BD, Minobe W, Abraham WT, et al. Changes in gene expression in the intact human heart. Downregulation of alpha-myosin heavy chain in hypertro­phied, failing ventricular myocardium. J Clin Invest. 1997;100(9):2315–24.
    • (1997) J Clin Invest , vol.100 , Issue.9 , pp. 2315-2324
    • Lowes, B.D.1    Minobe, W.2    Abraham, W.T.3
  • 72
    • 0021153417 scopus 로고
    • Expression of the cardiac ventricular alpha-and beta-myosin heavy chain genes is developmentally and hormonally regulated
    • Lompre A, Nadal-Ginard B, Mahdavi V. Expression of the cardiac ventricular alpha-and beta-myosin heavy chain genes is developmentally and hormonally regulated. J Biol Chem. 1984;259(10):6437–46.
    • (1984) J Biol Chem , vol.259 , Issue.10 , pp. 6437-6446
    • Lompre, A.1    Nadal-Ginard, B.2    Mahdavi, V.3
  • 73
    • 0025608774 scopus 로고
    • Developmental regulation of myosin gene expression in mouse cardiac muscle
    • Lyons G, Schiaffino S. Developmental regulation of myosin gene expression in mouse cardiac muscle. J Cell Biol. 1990;111(6):2427–36.
    • (1990) J Cell Biol , vol.111 , Issue.6 , pp. 2427-2436
    • Lyons, G.1    Schiaffino, S.2
  • 74
    • 0018728257 scopus 로고
    • Myosin isoenzyme redistribution in chronic heart overload
    • Lompre A, Schwartz K, D’Albis A. Myosin isoenzyme redistribution in chronic heart overload. Nature. 1979;282:105–7.
    • (1979) Nature , vol.282 , pp. 105-107
    • Lompre, A.1    Schwartz, K.2    D’Albis, A.3
  • 75
    • 0023120631 scopus 로고
    • Myosin heavy chain messenger RNA and protein isoform transitions during cardiac hypertrophy
    • Izumo S, Lompré AM, Matsuoka R, et al. Myosin heavy chain messenger RNA and protein isoform transitions during cardiac hypertrophy. J Clin Invest. 1987;79(3):970–7.
    • (1987) J Clin Invest , vol.79 , Issue.3 , pp. 970-977
    • Izumo, S.1    Lompré, A.M.2    Matsuoka, R.3
  • 76
    • 0023665075 scopus 로고
    • Hormonal regulation of myosin heavy chain and alpha-actin gene expression in cultured fetal rat heart myocytes
    • Gustafson T, Bahl J. Hormonal regulation of myosin heavy chain and alpha-actin gene expression in cultured fetal rat heart myocytes. J Biol Chem. 1987;262(27):13316–22.
    • (1987) J Biol Chem , vol.262 , Issue.27 , pp. 13316-13322
    • Gustafson, T.1    Bahl, J.2
  • 77
    • 84867679523 scopus 로고    scopus 로고
    • Increased afterload induces pathological cardiac hypertrophy: A new in vitro model
    • Hirt MN, Sörensen NA, Bartholdt LM, et al. Increased afterload induces pathological cardiac hypertrophy: a new in vitro model. Basic Res Cardiol. 2012;107(6):307.
    • (2012) Basic Res Cardiol , vol.107 , Issue.6
    • Hirt, M.N.1    Sörensen, N.A.2    Bartholdt, L.M.3
  • 78
    • 0035017153 scopus 로고    scopus 로고
    • Human cardiac myosin heavy chain isoforms in fetal and failing adult atria and ventricles
    • Reiser P, Portman M. Human cardiac myosin heavy chain isoforms in fetal and failing adult atria and ventricles. Am J Physiol Heart and Circ Physiol. 2001;2357:1814–20.
    • (2001) Am J Physiol Heart and Circ Physiol , vol.2357 , pp. 1814-1820
    • Reiser, P.1    Portman, M.2
  • 79
    • 0021669577 scopus 로고
    • Myosin changes in hyper­trophied human atrial and ventricular myocardium. A correlated immuno-fluorescence and quantitative immunochemical study on serial
    • Schiaffino S, Gorza L, Saggin L, Valfre C, Sartore S. Myosin changes in hyper­trophied human atrial and ventricular myocardium. A correlated immuno-fluorescence and quantitative immunochemical study on serial. Eur Heart J. 1984;75:95–102.
    • (1984) Eur Heart J , vol.75 , pp. 95-102
    • Schiaffino, S.1    Gorza, L.2    Saggin, L.3    Valfre, C.4    Sartore, S.5
  • 81
    • 0020551639 scopus 로고
    • Myosin isoenzymes in normal and hypertrophied human ventricular myocardium
    • Mercadier JJ, Bouveret P, Gorza L, et al. Myosin isoenzymes in normal and hypertrophied human ventricular myocardium. Circ Res. 1983;53:52–63.
    • (1983) Circ Res , vol.53 , pp. 52-63
    • Mercadier, J.J.1    Bouveret, P.2    Gorza, L.3
  • 82
    • 0024535042 scopus 로고
    • Distribution pattern of α and β myosin in normal and diseased human ventricular myocardium
    • Bouvagnet P, Mairhofer H, Leger JOC, Puech P, Leger JJ. Distribution pattern of α and β myosin in normal and diseased human ventricular myocardium. Basic Res Cardiol. 1989;84:91–102.
    • (1989) Basic Res Cardiol , vol.84 , pp. 91-102
    • Bouvagnet, P.1    Mairhofer, H.2    Leger, J.3    Puech, P.4    Leger, J.J.5
  • 83
    • 0034599128 scopus 로고    scopus 로고
    • Myosin heavy chain isoform expression in the failing and nonfailing human heart
    • Miyata S, Minobe W. Myosin heavy chain isoform expression in the failing and nonfailing human heart. Circ Res. 2000;86:386–91.
    • (2000) Circ Res , vol.86 , pp. 386-391
    • Miyata, S.1    Minobe, W.2
  • 84
    • 0030671503 scopus 로고    scopus 로고
    • Myosin heavy chain gene expression in human heart failure
    • Nakao K, Minobe W, Roden R. Myosin heavy chain gene expression in human heart failure. J Clin Invest. 1997;100(9):2362–70.
    • (1997) J Clin Invest , vol.100 , Issue.9 , pp. 2362-2370
    • Nakao, K.1    Minobe, W.2    Roden, R.3
  • 85
    • 0034828977 scopus 로고    scopus 로고
    • Loaded shortening and power output in cardiac myocytes are dependent on myosin heavy chain isoform expression
    • Herron T, Korte FS, McDonald KS. Loaded shortening and power output in cardiac myocytes are dependent on myosin heavy chain isoform expression. Am J Physiol Heart Circ Physiol. 2001;281:1217–22.
    • (2001) Am J Physiol Heart Circ Physiol , vol.281 , pp. 1217-1222
    • Herron, T.1    Korte, F.S.2    McDonald, K.S.3
  • 86
    • 0037076795 scopus 로고    scopus 로고
    • Small amounts of alpha- myosin heavy chain isoform expression significantly increase power output of rat cardiac myocyte fragments
    • Herron TJ, McDonald KS. Small amounts of alpha- myosin heavy chain isoform expression significantly increase power output of rat cardiac myocyte fragments. Circ Res. 2002;90:1150–3.
    • (2002) Circ Res , vol.90 , pp. 1150-1153
    • Herron, T.J.1    McDonald, K.S.2
  • 87
    • 34249715111 scopus 로고    scopus 로고
    • Sarcomere length dependence of rat skinned cardiac myocyte mechanical properties: Dependence on myosin heavy chain
    • Korte FS, McDonald KS. Sarcomere length dependence of rat skinned cardiac myocyte mechanical properties: dependence on myosin heavy chain. J Physiol. 2007;581(pt 2):725–39.
    • (2007) J Physiol , vol.581 , pp. 725-739
    • Korte, F.S.1    McDonald, K.S.2
  • 88
    • 23744469807 scopus 로고    scopus 로고
    • Power output is linearly related to MyHC content in rat skinned myocytes and isolated working hearts
    • Korte F, Herron T, Rovetto MJ, McDonald KS. Power output is linearly related to MyHC content in rat skinned myocytes and isolated working hearts. Am J Physiol Heart Circ Physiol. 2005;289:801–12.
    • (2005) Am J Physiol Heart Circ Physiol , vol.289 , pp. 801-812
    • Korte, F.1    Herron, T.2    Rovetto, M.J.3    McDonald, K.S.4
  • 89
    • 0033612182 scopus 로고    scopus 로고
    • Cardiac myosin binding protein C
    • Winegrad S. Cardiac myosin binding protein C. Circ Res. 1999;84:1117–26.
    • (1999) Circ Res , vol.84 , pp. 1117-1126
    • Winegrad, S.1
  • 90
    • 84885459245 scopus 로고    scopus 로고
    • Divergent effects of α- and β-myosin heavy chain iso­forms on the N terminus of rat cardiac troponin T
    • Mamidi R, Chandra M. Divergent effects of α- and β-myosin heavy chain iso­forms on the N terminus of rat cardiac troponin T. J Gen Physiol. 2013;142(4):413–23.
    • (2013) J Gen Physiol , vol.142 , Issue.4 , pp. 413-423
    • Mamidi, R.1    Chandra, M.2
  • 91
    • 0028178083 scopus 로고
    • Alpha – tropomyosin and cardiac troponin T mutations cause familial hypettrophic cardiomyopathy: A disease of the sarcomere
    • Thierfelder L, Watkins H, MacRae C, et al. Alpha – tropomyosin and cardiac troponin T mutations cause familial hypettrophic cardiomyopathy: a disease of the sarcomere. Cell. 1994;77:701–12.
    • (1994) Cell , vol.77 , pp. 701-712
    • Thierfelder, L.1    Watkins, H.2    Macrae, C.3
  • 92
    • 50649083738 scopus 로고    scopus 로고
    • Functional effects of the hypertrophic cardiomyopathy R403Q mutation are different in an alpha- or beta-myosin heavy chain backbone
    • Lowey S, Lesko LM, Rovner AS, et al. Functional effects of the hypertrophic cardiomyopathy R403Q mutation are different in an alpha- or beta-myosin heavy chain backbone. J Biol Chem. 2008;283(29):20579–89.
    • (2008) J Biol Chem , vol.283 , Issue.29 , pp. 20579-20589
    • Lowey, S.1    Lesko, L.M.2    Rovner, A.S.3
  • 93
    • 84865534880 scopus 로고    scopus 로고
    • Effects of R92 mutations in mouse cardiac troponin T are influenced by changes in myosin heavy chain isoform
    • Ford SJ, Mamidi R, Jimenez J, Tardiff JC, Chandra M. Effects of R92 mutations in mouse cardiac troponin T are influenced by changes in myosin heavy chain isoform. J Mol Cell Cardiol. 2012;53(4):542–51.
    • (2012) J Mol Cell Cardiol , vol.53 , Issue.4 , pp. 542-551
    • Ford, S.J.1    Mamidi, R.2    Jimenez, J.3    Tardiff, J.C.4    Chandra, M.5
  • 94
    • 77954760209 scopus 로고    scopus 로고
    • Development of a drug screening plat­form based on engineered heart tissue
    • Hansen A, Eder A, Bönstrup M, et al. Development of a drug screening plat­form based on engineered heart tissue. Circ Res. 2010;107(1):35–44.
    • (2010) Circ Res , vol.107 , Issue.1 , pp. 35-44
    • Hansen, A.1    Eder, A.2    Bönstrup, M.3
  • 95
    • 84894626455 scopus 로고    scopus 로고
    • Engineering cardiac tissues from pluripo­tent stem cells for drug screening and studies of cell maturation
    • Miklas JW, Nunes SS, Radisic M. Engineering cardiac tissues from pluripo­tent stem cells for drug screening and studies of cell maturation. Isr J Chem. 2013;53:680–94.
    • (2013) Isr J Chem , vol.53 , pp. 680-694
    • Miklas, J.W.1    Nunes, S.S.2    Radisic, M.3
  • 96
    • 0032943836 scopus 로고    scopus 로고
    • Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the α cardiac myosin heavy chain gene
    • Fatkin D, Christe ME, Aristizabal O, et al. Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the α cardiac myosin heavy chain gene. J Clin Invest. 1999;103(1):147–53.
    • (1999) J Clin Invest , vol.103 , Issue.1 , pp. 147-153
    • Fatkin, D.1    Christe, M.E.2    Aristizabal, O.3
  • 97
    • 0027226230 scopus 로고
    • Structure of the actin-myosin complex and its implications for muscle contraction
    • Rayment I, Holden HM, Whittaker M, et al. Structure of the actin-myosin complex and its implications for muscle contraction. Science. 1993;261:58–65.
    • (1993) Science , vol.261 , pp. 58-65
    • Rayment, I.1    Holden, H.M.2    Whittaker, M.3
  • 98
    • 9344244157 scopus 로고    scopus 로고
    • Basal myosin light chain phosphorylation is a determinant of Ca 2+ sensitivity of force and activation dependence of the kinetics of myocardial force development
    • Olsson M, Patel J, Fitzsimons D. Basal myosin light chain phosphorylation is a determinant of Ca 2+ sensitivity of force and activation dependence of the kinetics of myocardial force development. Am J Physiol Heart Circ Physiol. 2004;287:2712–8.
    • (2004) Am J Physiol Heart Circ Physiol , vol.287 , pp. 2712-2718
    • Olsson, M.1    Patel, J.2    Fitzsimons, D.3
  • 99
    • 0026437783 scopus 로고
    • Differential regulation of the atrial isoforms of the myosin light chains during striated muscle development
    • Hailstones D, Barton P, Chan-thomas P, Sasse S, Sutherlandll C, Hardemanll E. Differential regulation of the atrial isoforms of the myosin light chains during striated muscle development. J Biol Chem. 1992;267(32):23295–300.
    • (1992) J Biol Chem , vol.267 , Issue.32 , pp. 23295-23300
    • Hailstones, D.1    Barton, P.2    Chan-Thomas, P.3    Sasse, S.4    Sutherlandll, C.5    Hardemanll, E.6
  • 100
    • 0032554677 scopus 로고    scopus 로고
    • Effects of total replace­ment of atrial myosin light chain-2 with the ventricular isoform in atrial myo­cytes of transgenic mice
    • Pawloski-Dahm CM, Song G, Kirkpatrick DL, et al. Effects of total replace­ment of atrial myosin light chain-2 with the ventricular isoform in atrial myo­cytes of transgenic mice. Circulation. 1998;97:1508–13.
    • (1998) Circulation , vol.97 , pp. 1508-1513
    • Pawloski-Dahm, C.M.1    Song, G.2    Kirkpatrick, D.L.3
  • 101
    • 0032958598 scopus 로고    scopus 로고
    • Myosin light chain 2a and 2v identifies the embryonic outflow tract myocardium in the developing rodent heart
    • Franco D, Markman M, Wagenaar G, Moorman A. Myosin light chain 2a and 2v identifies the embryonic outflow tract myocardium in the developing rodent heart. Anat Rec. 1999;254:135–46.
    • (1999) Anat Rec , vol.254 , pp. 135-146
    • Franco, D.1    Markman, M.2    Wagenaar, G.3    Moorman, A.4
  • 102
    • 84884954445 scopus 로고    scopus 로고
    • Myosin light chain 2-based selec­tion of human iPSC-derived early vnetricular cardiac myocytes
    • Bizy A, Guerrero-Serna G, Hu B, et al. Myosin light chain 2-based selec­tion of human iPSC-derived early vnetricular cardiac myocytes. Stem Cell Res. 2013;11(3):1335–47.
    • (2013) Stem Cell Res , vol.11 , Issue.3 , pp. 1335-1347
    • Bizy, A.1    Guerrero-Serna, G.2    Hu, B.3
  • 103
    • 84901335911 scopus 로고    scopus 로고
    • Ventricular myosin modifies in vitro step-size when phosphorylated
    • Wang Y, Ajtai K, Burghardt TP. Ventricular myosin modifies in vitro step-size when phosphorylated. J Mol Cell Cardiol. 2014;72:231–7.
    • (2014) J Mol Cell Cardiol , vol.72 , pp. 231-237
    • Wang, Y.1    Ajtai, K.2    Burghardt, T.P.3
  • 104
    • 84859715525 scopus 로고    scopus 로고
    • Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease
    • Sheikh F, Ouyang K, Campbell SG, et al. Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease. J Clin Invest. 2012;122(4):1209–21.
    • (2012) J Clin Invest , vol.122 , Issue.4 , pp. 1209-1221
    • Sheikh, F.1    Ouyang, K.2    Campbell, S.G.3
  • 105
    • 34250809531 scopus 로고    scopus 로고
    • Frequency-dependent acceleration of relaxation involves decreased myofilament calcium sensitivity
    • Varian KD, Janssen PML. Frequency-dependent acceleration of relaxation involves decreased myofilament calcium sensitivity. Am J Physiol Heart Circ Physiol. 2007;92:2212–9.
    • (2007) Am J Physiol Heart Circ Physiol , vol.92 , pp. 2212-2219
    • Varian, K.D.1    Janssen, P.2
  • 106
    • 40949106071 scopus 로고    scopus 로고
    • Identification of cardiac-specific myosin light chain kinase
    • Chan JY, Takeda M, Briggs LE, et al. Identification of cardiac-specific myosin light chain kinase. Circ Res. 2008;102(5):571–80.
    • (2008) Circ Res , vol.102 , Issue.5 , pp. 571-580
    • Chan, J.Y.1    Takeda, M.2    Briggs, L.E.3
  • 107
    • 78650334298 scopus 로고    scopus 로고
    • Cardiac myosin light chain kinase is necessary for myosin regulatory light chain phosphorylation and cardiac performance in vivo
    • Ding P, Huang J, Battiprolu PK, Hill JA, Kamm KE, Stull JT. Cardiac myosin light chain kinase is necessary for myosin regulatory light chain phosphorylation and cardiac performance in vivo. J Biol Chem. 2010;285(52):40819–29.
    • (2010) J Biol Chem , vol.285 , Issue.52 , pp. 40819-40829
    • Ding, P.1    Huang, J.2    Battiprolu, P.K.3    Hill, J.A.4    Kamm, K.E.5    Stull, J.T.6
  • 108
    • 0037588762 scopus 로고    scopus 로고
    • Structure of the core domain of human cardiac troponin in the Ca2+ -saturated form
    • Takeda S, Yamashita A, Maeda K, Mae Y. Structure of the core domain of human cardiac troponin in the Ca2+ -saturated form. Nature. 2003;424(7):35–41.
    • (2003) Nature , vol.424 , Issue.7 , pp. 35-41
    • Takeda, S.1    Yamashita, A.2    Maeda, K.3    Mae, Y.4
  • 109
    • 0028135302 scopus 로고
    • Tension production and thin-filament protein isoforms in developing rat myocardium
    • Reiser P, Westfall M, Schiaffino S, Solaro J. Tension production and thin-filament protein isoforms in developing rat myocardium. Am J Physiol Heart Circ Physiol. 1994;36:H1589–96.
    • (1994) Am J Physiol Heart Circ Physiol , vol.36 , pp. H1589-H1596
    • Reiser, P.1    Westfall, M.2    Schiaffino, S.3    Solaro, J.4
  • 110
    • 0038069065 scopus 로고    scopus 로고
    • Developmental changes in contractility and sarcomeric proteins from the early embryonic to the adult stage in the mouse heart
    • Siedner S, Krüger M, Schroeter M, et al. Developmental changes in contractility and sarcomeric proteins from the early embryonic to the adult stage in the mouse heart. J Physiol. 2003;548(pt 2):493–505.
    • (2003) J Physiol , vol.548 , pp. 493-505
    • Siedner, S.1    Krüger, M.2    Schroeter, M.3
  • 111
    • 0346120211 scopus 로고    scopus 로고
    • Modulation of thin filament activation by break­down or isoform switching of thin filament proteins: Physiological and patho­logical implications
    • Marston SB, Redwood CS. Modulation of thin filament activation by break­down or isoform switching of thin filament proteins: physiological and patho­logical implications. Circ Res. 2003;93(12):1170–8.
    • (2003) Circ Res , vol.93 , Issue.12 , pp. 1170-1178
    • Marston, S.B.1    Redwood, C.S.2
  • 112
    • 0025884010 scopus 로고
    • Force-pCa rela­tion and troponin T isoforms of rabbit myocardium
    • Nassar R, Malouf NN, Kelly MB, Oakeley AE, Anderson PAW. Force-pCa rela­tion and troponin T isoforms of rabbit myocardium. Circ Res. 1991;69:1470–6.
    • (1991) Circ Res , vol.69 , pp. 1470-1476
    • Nassar, R.1    Malouf, N.N.2    Kelly, M.B.3    Oakeley, A.E.4    Erson, P.5
  • 113
    • 0015218120 scopus 로고
    • Reconstitution of troponin activity from three protein components
    • Greaser M, Gergely J. Reconstitution of troponin activity from three protein components. J Biol Chem. 1971;246(18):4226–33.
    • (1971) J Biol Chem , vol.246 , Issue.18 , pp. 4226-4233
    • Greaser, M.1    Gergely, J.2
  • 114
    • 0035321086 scopus 로고    scopus 로고
    • Skeletal and cardiac muscle contractile activation: Tropomyosin “rocks and rolls ”
    • Gordon AM, Regnier M, Homsher E. Skeletal and cardiac muscle contractile activation: tropomyosin “rocks and rolls ”. News Physiol Sci. 2001;16(4):49–55.
    • (2001) News Physiol Sci , vol.16 , Issue.4 , pp. 49-55
    • Gordon, A.M.1    Regnier, M.2    Homsher, E.3
  • 115
    • 15544390385 scopus 로고    scopus 로고
    • Calcium, thin filaments, and the integrative biology of cardiac contractility
    • Kobayashi T, Solaro RJ. Calcium, thin filaments, and the integrative biology of cardiac contractility. Annu Rev Physiol. 2005;67:39–67.
    • (2005) Annu Rev Physiol , vol.67 , pp. 39-67
    • Kobayashi, T.1    Solaro, R.J.2
  • 116
    • 0027499184 scopus 로고
    • Troponin I gene expression during human cardiac development and in end-stage heart failure
    • Sasse S, Brand NJ, Kyprianou P, et al. Troponin I gene expression during human cardiac development and in end-stage heart failure. Circ Res. 1993;72:932–9.
    • (1993) Circ Res , vol.72 , pp. 932-939
    • Sasse, S.1    Brand, N.J.2    Kyprianou, P.3
  • 117
    • 0030904641 scopus 로고    scopus 로고
    • Phosphorylation-induced distance change in a cardiac muscle troponin I mutant
    • Dong W, Chandra M, Xing J, She M, Solaro RJ, Cheung HC. Phosphorylation-induced distance change in a cardiac muscle troponin I mutant. Biochemistry. 1997;36:6754–61.
    • (1997) Biochemistry , vol.36 , pp. 6754-6761
    • Dong, W.1    Chandra, M.2    Xing, J.3    She, M.4    Solaro, R.J.5    Cheung, H.C.6
  • 118
    • 0033563035 scopus 로고    scopus 로고
    • Impaired cardiomyocyte relaxation and diastolic function in transgenic mice expressing slow skeletal troponin I in the heart
    • Fentzke RC, Buck SH, Patel JR, et al. Impaired cardiomyocyte relaxation and diastolic function in transgenic mice expressing slow skeletal troponin I in the heart. J Physiol. 1999;517(1):143–57.
    • (1999) J Physiol , vol.517 , Issue.1 , pp. 143-157
    • Fentzke, R.C.1    Buck, S.H.2    Patel, J.R.3
  • 119
    • 36349031141 scopus 로고    scopus 로고
    • Cardiac troponin I threonine 144: Role in myofilament length dependent activation
    • Tachampa K, Wang H, Farman GP, De Tombe PP. Cardiac troponin I threonine 144: role in myofilament length dependent activation. Circ Res. 2007;101(11):1081–3.
    • (2007) Circ Res , vol.101 , Issue.11 , pp. 1081-1083
    • Tachampa, K.1    Wang, H.2    Farman, G.P.3    De Tombe, P.P.4
  • 120
    • 84934436389 scopus 로고    scopus 로고
    • Heart failure, ischemia/reperfusion injury and cardiac troponin
    • In: Ebashi S, Ohtsuki I, eds., Berlin: Springer
    • Solaro RJ, Arteaga GM. Heart failure, ischemia/reperfusion injury and cardiac troponin. In: Ebashi S, Ohtsuki I, eds. Regulatory Mechanisms of Striated Muscle Contraction. Berlin: Springer; 2007:191–200.
    • (2007) Regulatory Mechanisms of Striated Muscle Contraction , pp. 191-200
    • Solaro, R.J.1    Arteaga, G.M.2
  • 121
    • 84908052815 scopus 로고    scopus 로고
    • Acquisition of a quantitative, stoichio­metrically conserved ratiometric marker of maturation status in stem cell-derived cardiac myocytes
    • Bedada FB, Chan SS, Metzger SK, et al. Acquisition of a quantitative, stoichio­metrically conserved ratiometric marker of maturation status in stem cell-derived cardiac myocytes. Stem cell Rep. 2014;3(4):594–605.
    • (2014) Stem Cell Rep , vol.3 , Issue.4 , pp. 594-605
    • Bedada, F.B.1    Chan, S.S.2    Metzger, S.K.3
  • 122
    • 77952481131 scopus 로고    scopus 로고
    • Cardiac titin: A multifunctional giant
    • LeWinter MM, Granzier H. Cardiac titin: a multifunctional giant. Circulation. 2010;121(19):2137–45.
    • (2010) Circulation , vol.121 , Issue.19 , pp. 2137-2145
    • Lewinter, M.M.1    Granzier, H.2
  • 123
    • 1842830381 scopus 로고    scopus 로고
    • Developmentally regulated switching of titin size alters myofibrillar stiffness in the perinatal heart
    • Opitz CA, Leake MC, Makarenko I, Benes V, Linke WA. Developmentally regulated switching of titin size alters myofibrillar stiffness in the perinatal heart. Circ Res. 2004;94(7):967–75.
    • (2004) Circ Res , vol.94 , Issue.7 , pp. 967-975
    • Opitz, C.A.1    Leake, M.C.2    Makarenko, I.3    Benes, V.4    Linke, W.A.5
  • 124
    • 1242281665 scopus 로고    scopus 로고
    • Developmental control of titin isoform expression and passive stiffness in fetal and neonatal myocardium
    • Lahmers S, Wu Y, Call DR, Labeit S, Granzier H. Developmental control of titin isoform expression and passive stiffness in fetal and neonatal myocardium. Circ Res. 2004;94(4):505–13.
    • (2004) Circ Res , vol.94 , Issue.4 , pp. 505-513
    • Lahmers, S.1    Wu, Y.2    Call, D.R.3    Labeit, S.4    Granzier, H.5
  • 125
    • 61449104424 scopus 로고    scopus 로고
    • Titin-based mechanical signalling in normal and failing myocardium
    • Krüger M, Linke WA. Titin-based mechanical signalling in normal and failing myocardium. J Mol Cell Cardiol. 2009;46(4):490–8.
    • (2009) J Mol Cell Cardiol , vol.46 , Issue.4 , pp. 490-498
    • Krüger, M.1    Linke, W.A.2
  • 126
    • 1242342244 scopus 로고    scopus 로고
    • The giant protein titin: A major player in myocardial mechanics, signaling, and disease
    • Granzier HL, Labeit S. The giant protein titin: a major player in myocardial mechanics, signaling, and disease. Circ Res. 2004;94(3):284–95.
    • (2004) Circ Res , vol.94 , Issue.3 , pp. 284-295
    • Granzier, H.L.1    Labeit, S.2
  • 127
    • 3142672018 scopus 로고    scopus 로고
    • Altered titin expression, myocardial stiffness, and left ventricular function in patients with dilated cardiomyopathy
    • Nagueh SF, Shah G, Wu Y, et al. Altered titin expression, myocardial stiffness, and left ventricular function in patients with dilated cardiomyopathy. Circula­tion. 2004;110(2):155–62.
    • (2004) Circula­tion , vol.110 , Issue.2 , pp. 155-162
    • Nagueh, S.F.1    Shah, G.2    Wu, Y.3
  • 128
    • 41949113903 scopus 로고    scopus 로고
    • Thyroid hormone regulates developmental titin isoform transitions via the phosphatidylinositol-3-kinase/AKT pathway
    • Krüger M, Sachse C, Zimmermann WH, Eschenhagen T, Klede S, Linke WA. Thyroid hormone regulates developmental titin isoform transitions via the phosphatidylinositol-3-kinase/AKT pathway. Circ Res. 2008;102(4):439–47.
    • (2008) Circ Res , vol.102 , Issue.4 , pp. 439-447
    • Krüger, M.1    Sachse, C.2    Zimmermann, W.H.3    Eschenhagen, T.4    Klede, S.5    Linke, W.A.6
  • 129
    • 77955526103 scopus 로고    scopus 로고
    • The giant protein titin as an integrator of myocyte signal­ing pathways
    • Linke WA, Krüger M. The giant protein titin as an integrator of myocyte signal­ing pathways. Physiology (Bethesda). 2010;25(3):186–98.
    • (2010) Physiology (Bethesda) , vol.25 , Issue.3 , pp. 186-198
    • Linke, W.A.1    Krüger, M.2
  • 130
    • 0344896768 scopus 로고    scopus 로고
    • Titin isoform variance and length dependence of activation in skinned bovine cardiac muscle
    • Fukuda N, Wu Y, Farman G, Irving TC, Granzier H. Titin isoform variance and length dependence of activation in skinned bovine cardiac muscle. J Physiol. 2003;553(pt 1):147–54.
    • (2003) J Physiol , vol.553 , pp. 147-154
    • Fukuda, N.1    Wu, Y.2    Farman, G.3    Irving, T.C.4    Granzier, H.5
  • 131
    • 40849096222 scopus 로고    scopus 로고
    • The unique functions of cardiac troponin I in the control of cardiac muscle contraction and relaxation
    • Solaro RJ, Rosevear P, Kobayashi T. The unique functions of cardiac troponin I in the control of cardiac muscle contraction and relaxation. Biochem Biophys Res Commun. 2008;369(1):82–7.
    • (2008) Biochem Biophys Res Commun , vol.369 , Issue.1 , pp. 82-87
    • Solaro, R.J.1    Rosevear, P.2    Kobayashi, T.3
  • 132
    • 84883409690 scopus 로고    scopus 로고
    • Altered ven­tricular torsion and transmural patterns of myocyte relaxation precede heart failure in aging F344 rats
    • Campbell SG, Haynes P, Kelsey Snapp W, Nava KE, Campbell KS. Altered ven­tricular torsion and transmural patterns of myocyte relaxation precede heart failure in aging F344 rats. Am J Physiol Heart Circ Physiol. 2013;305(5):H676–86.
    • (2013) Am J Physiol Heart Circ Physiol , vol.305 , Issue.5 , pp. H676-H686
    • Campbell, S.G.1    Haynes, P.2    Kelsey Snapp, W.3    Nava, K.E.4    Campbell, K.S.5
  • 133
    • 84915820071 scopus 로고    scopus 로고
    • Decreased polycystin 2 expression alters calcium-contraction coupling and changes β-adrenergic signaling pathways
    • Kuo IY, Kwaczala AT, Nguyen L, Russell KS, Campbell SG, Ehrlich BE. Decreased polycystin 2 expression alters calcium-contraction coupling and changes β-adrenergic signaling pathways. Proc Natl Acad Sci U S A. 2014;111(46):16604–9.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , Issue.46 , pp. 16604-16609
    • Kuo, I.Y.1    Kwaczala, A.T.2    Nguyen, L.3    Russell, K.S.4    Campbell, S.G.5    Ehrlich, B.E.6
  • 134
    • 0017176627 scopus 로고
    • Phosphorylation of the inhibitory subunit of troponin and its effect on the calcium dependence of cardiac myofibril adenosine triphosphatase
    • Ray K, England P. Phosphorylation of the inhibitory subunit of troponin and its effect on the calcium dependence of cardiac myofibril adenosine triphosphatase. FEBS Lett. 1976;70:1.
    • (1976) FEBS Lett , vol.70
    • Ray, K.1    England, P.2
  • 135
    • 0029559638 scopus 로고
    • Phosphorylation of both serine residues in cardiac troponin I is required to decrease the Ca affinity of cardiac troponin C
    • Zhang R, Zhao J, Potter JD. Phosphorylation of both serine residues in cardiac troponin I is required to decrease the Ca affinity of cardiac troponin C. J Biol Chem. 1995;270(51):30773–80.
    • (1995) J Biol Chem , vol.270 , Issue.51 , pp. 30773-30780
    • Zhang, R.1    Zhao, J.2    Potter, J.D.3
  • 136
    • 0345743543 scopus 로고    scopus 로고
    • Abnormal frequency-dependent responses represent the pathophysiologic signature of contractile failure in human myocardium
    • Rossman EI, Petre RE, Chaudhary KW, et al. Abnormal frequency-dependent responses represent the pathophysiologic signature of contractile failure in human myocardium. J Mol Cell Cardiol. 2004;36(1):33–42.
    • (2004) J Mol Cell Cardiol , vol.36 , Issue.1 , pp. 33-42
    • Rossman, E.I.1    Petre, R.E.2    Chaudhary, K.W.3
  • 137
    • 84928782226 scopus 로고    scopus 로고
    • Dissociation of calcium tran­sients and force development following a change in stimulation frequency in iso­lated rabbit myocardium
    • Haizlip KM, Milani-nejad N, Brunello L, et al. Dissociation of calcium tran­sients and force development following a change in stimulation frequency in iso­lated rabbit myocardium. Biomed Res Int. 2015;2015:12.
    • (2015) Biomed Res Int , vol.2015
    • Haizlip, K.M.1    Milani-Nejad, N.2    Brunello, L.3
  • 138
    • 9544240359 scopus 로고    scopus 로고
    • Existence of the Frank-Starling mechanism in the failing human heart Investigations on the organ, tissue, and sarcomere levels
    • Holubarsch C, Ruf T, Goldstein DJ, et al. Existence of the Frank-Starling mechanism in the failing human heart Investigations on the organ, tissue, and sarcomere levels. Circulation. 1996;94(4):683–9.
    • (1996) Circulation , vol.94 , Issue.4 , pp. 683-689
    • Holubarsch, C.1    Ruf, T.2    Goldstein, D.J.3
  • 139
    • 79958815977 scopus 로고    scopus 로고
    • Assessment of contractility in intact ven­tricular cardiomyocytes using the dimensionless “Frank–Starling Gain”index
    • Bollensdorff C, Lookin O, Kohl P. Assessment of contractility in intact ven­tricular cardiomyocytes using the dimensionless “Frank–Starling Gain”index. Pflugers Arch. 2011;462:39–48.
    • (2011) Pflugers Arch , vol.462 , pp. 39-48
    • Bollensdorff, C.1    Lookin, O.2    Kohl, P.3


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