Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome

Nature

Volumn 471, Issue 7337, 2011, Pages 230-236

  Yazawa, Masayuki ^a   Hsueh, Brian ^a,b   Jia, Xiaolin ^a,c   Pasca, Anca M ^a,d   Bernstein, Jonathan A ^a   Hallmayer, Joachim ^a   Dolmetsch, Ricardo E ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PRINCETON UNIVERSITY   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; ROSCOVITINE;

ASSAY; CALCIUM; CARDIOLOGY; CARDIOVASCULAR DISEASE; CELL ORGANELLE; DEVELOPMENTAL BIOLOGY; ELECTRICAL METHOD; ENVIRONMENTAL FACTOR; MOLECULAR ANALYSIS; MUTATION; PHENOTYPE;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL DIFFERENTIATION; CONTROLLED STUDY; ELECTRIC ACTIVITY; ELECTROPHYSIOLOGY; EMBRYO; GENE EXPRESSION PROFILING; GENE MUTATION; GENETIC DISORDER; HEART ARRHYTHMIA; HEART CONTRACTION; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; HEART VENTRICLE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; NUCLEOTIDE SEQUENCE; PHENOTYPE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SKIN CELL; TIMOTHY SYNDROME;

ACTION POTENTIALS; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; CELL TRANSDIFFERENTIATION; DRUG EVALUATION, PRECLINICAL; FIBROBLASTS; HEK293 CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; LONG QT SYNDROME; MUTATION, MISSENSE; MYOCYTES, CARDIAC; NUCLEAR REPROGRAMMING; PATCH-CLAMP TECHNIQUES; PHENOTYPE; PURINES; SINGLE-CELL ANALYSIS; SYNDACTYLY;

PHLEUM PRATENSE;

EID: 79952438377     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature09855     Document Type: Article

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