메뉴 건너뛰기




Volumn 29, Issue 3, 2014, Pages 214-219

Human-induced pluripotent stem cell models of inherited cardiomyopathies

Author keywords

arrhythmogenic right ventricular cardiomyopathy; dilated cardiomyopathy; hypertrophic cardiomyopathy,induced pluripotent stem cells; inherited cardiomyopathy

Indexed keywords

CARDIOMYOPATHY; CONGESTIVE CARDIOMYOPATHY; FAMILIAL DISEASE; FAMILIAL HYPERTROPHIC CARDIOMYOPATHY; HEART MUSCLE CELL; HEART PROARRHYTHMIA; HEART RIGHT VENTRICLE DYSPLASIA; HUMAN; MUTATION; PATHOGENESIS; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; RESTRICTIVE CARDIOMYOPATHY; REVIEW; VENTRICULAR NONCOMPACTION; ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA; BIOLOGICAL MODEL; CARDIOMYOPATHY, DILATED; CARDIOMYOPATHY, HYPERTROPHIC, FAMILIAL; DRUG DEVELOPMENT; DRUG EFFECTS; GENETIC ASSOCIATION; IN VITRO STUDY; PATHOLOGY; PROCEDURES; TRENDS;

EID: 84899480082     PISSN: 02684705     EISSN: 15317080     Source Type: Journal    
DOI: 10.1097/HCO.0000000000000049     Document Type: Review
Times cited : (25)

References (24)
  • 2
    • 77649185345 scopus 로고    scopus 로고
    • Progress with genetic cardiomyopathies: Screening, counseling, and testing in dilated, hypertrophic, and arrhythmogenic right ventricular dysplasia/cardiomyopathy
    • Hershberger RE, Cowan J, Morales A, et al. Progress with genetic cardiomyopathies: screening, counseling, and testing in dilated, hypertrophic, and arrhythmogenic right ventricular dysplasia/cardiomyopathy. Circ Heart Fail 2009; 2:253-261.
    • (2009) Circ Heart Fail , vol.2 , pp. 253-261
    • Hershberger, R.E.1    Cowan, J.2    Morales, A.3
  • 3
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al. Embryonic stem cell lines derived from human blastocysts. Science 1998; 282:1145-1147.
    • (1998) Science , vol.282 , pp. 1145-1147
    • Thomson, J.A.1    Itskovitz-Eldor, J.2    Shapiro, S.S.3
  • 4
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007; 131:861-872.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3
  • 5
    • 84856258171 scopus 로고    scopus 로고
    • Mechanisms of disease: Hypertrophic cardiomyopathy
    • Frey N, Luedde M, Katus HA. Mechanisms of disease: hypertrophic cardiomyopathy. Nat Rev Cardiol 2012; 9:91-100.
    • (2012) Nat Rev Cardiol , vol.9 , pp. 91-100
    • Frey, N.1    Luedde, M.2    Katus, H.A.3
  • 6
    • 84872026086 scopus 로고    scopus 로고
    • Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells
    • Lan F, Lee AS, Liang P, et al. Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells. Cell Stem Cell 2013; 12:101-113.
    • (2013) Cell Stem Cell , vol.12 , pp. 101-113
    • Lan, F.1    Lee, A.S.2    Liang, P.3
  • 7
    • 79956110261 scopus 로고    scopus 로고
    • Human cardiomyopathy mutations induce myocyte hyperplasia and activate hypertrophic pathways during cardiogenesis in Zebrafish
    • Becker JR, Deo RC, Werdich AA, et al. Human cardiomyopathy mutations induce myocyte hyperplasia and activate hypertrophic pathways during cardiogenesis in Zebrafish. Dis Model Mech 2011; 4:400-410.
    • (2011) Dis Model Mech , vol.4 , pp. 400-410
    • Becker, J.R.1    Deo, R.C.2    Werdich, A.A.3
  • 8
    • 0030067394 scopus 로고    scopus 로고
    • A mouse model of familial hypertrophic cardiomyopathy
    • Geisterfer-Lowrance AA, Christe M, Conner DA, et al. A mouse model of familial hypertrophic cardiomyopathy. Science 1996; 272:731-734.
    • (1996) Science , vol.272 , pp. 731-734
    • Geisterfer-Lowrance, A.A.1    Christe, M.2    Conner, D.A.3
  • 9
    • 84883163817 scopus 로고    scopus 로고
    • Dilated cardiomyopathy: The complexity of a diverse genetic architecture
    • Hershberger RE, Hedges DJ, Morales A. Dilated cardiomyopathy: the complexity of a diverse genetic architecture. Nat Rev Cardiol 2013; 10:531-547.
    • (2013) Nat Rev Cardiol , vol.10 , pp. 531-547
    • Hershberger, R.E.1    Hedges, D.J.2    Morales, A.3
  • 10
    • 84860156650 scopus 로고    scopus 로고
    • Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy
    • Sun N, Yazawa M, Liu J, et al. Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy. Sci Transl Med 2012; 4:130ra47.
    • (2012) Sci Transl Med , vol.4 , pp. 130-147
    • Sun, N.1    Yazawa, M.2    Liu, J.3
  • 11
    • 84875276852 scopus 로고    scopus 로고
    • Patient-specific induced-pluripotent stem cells-derived cardiomyocytes recapitulate the pathogenic phenotypes of dilated cardiomyopathy due to a novel des mutation identified by whole exome sequencing
    • Tse HF, Ho JC, Choi SW, et al. Patient-specific induced-pluripotent stem cells-derived cardiomyocytes recapitulate the pathogenic phenotypes of dilated cardiomyopathy due to a novel des mutation identified by whole exome sequencing. Hum Mol Genet 2013; 22:1395-1403.
    • (2013) Hum Mol Genet , vol.22 , pp. 1395-1403
    • Tse, H.F.1    Ho, J.C.2    Choi, S.W.3
  • 12
    • 84872506168 scopus 로고    scopus 로고
    • Modeling of lamin a/C mutation premature cardiac aging using patient-specific induced pluripotent stem cells
    • Siu CW, Lee YK, Ho JC, et al. Modeling of lamin a/C mutation premature cardiac aging using patient-specific induced pluripotent stem cells. Aging (Albany NY) 2012; 4:803-822.
    • (2012) Aging (Albany NY) , vol.4 , pp. 803-822
    • Siu, C.W.1    Lee, Y.K.2    Ho, J.C.3
  • 13
    • 42649092901 scopus 로고    scopus 로고
    • Mechanisms of disease: Molecular genetics of arrhythmogenic right ventricular dysplasia/cardiomyopathy
    • Awad MM, Calkins H, Judge DP. Mechanisms of disease: molecular genetics of arrhythmogenic right ventricular dysplasia/cardiomyopathy. Nat Clin Pract Cardiovasc Med 2008; 5:258-267.
    • (2008) Nat Clin Pract Cardiovasc Med , vol.5 , pp. 258-267
    • Awad, M.M.1    Calkins, H.2    Judge, D.P.3
  • 14
    • 84874741888 scopus 로고    scopus 로고
    • Studying arrhythmogenic right ventricular dysplasia with patient-specific IPSCs
    • Kim C, Wong J, Wen J, et al. Studying arrhythmogenic right ventricular dysplasia with patient-specific IPSCs. Nature 2013; 494:105-110.
    • (2013) Nature , vol.494 , pp. 105-110
    • Kim, C.1    Wong, J.2    Wen, J.3
  • 15
    • 84876522952 scopus 로고    scopus 로고
    • Generation of patient-specific induced pluripotent stem cell-derived cardiomyocytes as a cellular model of arrhythmogenic right ventricular cardiomyopathy
    • Ma D, Wei H, Lu J, et al. Generation of patient-specific induced pluripotent stem cell-derived cardiomyocytes as a cellular model of arrhythmogenic right ventricular cardiomyopathy. Eur Heart J 2013; 34:1122-1133.
    • (2013) Eur Heart J , vol.34 , pp. 1122-1133
    • Ma, D.1    Wei, H.2    Lu, J.3
  • 16
    • 84892415382 scopus 로고    scopus 로고
    • Modeling of arrhythmogenic right ventricular cardiomyopathy with human induced pluripotent stem cells
    • Caspi O, Huber I, Gepstein A, et al. Modeling of arrhythmogenic right ventricular cardiomyopathy with human induced pluripotent stem cells. Circ Cardiovasc Genet 2013; 6:557-568.
    • (2013) Circ Cardiovasc Genet , vol.6 , pp. 557-568
    • Caspi, O.1    Huber, I.2    Gepstein, A.3
  • 17
    • 84887949485 scopus 로고    scopus 로고
    • Patient-specific stem cells and cardiovascular drug discovery
    • Mordwinkin NM, Lee AS, Wu JC. Patient-specific stem cells and cardiovascular drug discovery. JAMA 2013; 310:2039-2040.
    • (2013) JAMA , vol.310 , pp. 2039-2040
    • Mordwinkin, N.M.1    Lee, A.S.2    Wu, J.C.3
  • 18
    • 84859344815 scopus 로고    scopus 로고
    • Clinical and genetic determinants of torsade de pointes risk
    • Sauer AJ, Newton-Cheh C. Clinical and genetic determinants of torsade de pointes risk. Circulation 2012; 125:1684-1694.
    • (2012) Circulation , vol.125 , pp. 1684-1694
    • Sauer, A.J.1    Newton-Cheh, C.2
  • 19
    • 84862907693 scopus 로고    scopus 로고
    • Production of de novo cardiomyocytes: Human pluripotent stem cell differentiation and direct reprogramming
    • Burridge PW, Keller G, Gold JD, et al. Production of de novo cardiomyocytes: human pluripotent stem cell differentiation and direct reprogramming. Cell Stem Cell 2012; 10:16-28.
    • (2012) Cell Stem Cell , vol.10 , pp. 16-28
    • Burridge, P.W.1    Keller, G.2    Gold, J.D.3
  • 20
    • 84876526111 scopus 로고    scopus 로고
    • Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity
    • Liang P, Lan F, Lee AS, et al. Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity. Circulation 2013; 127:1677-1691.
    • (2013) Circulation , vol.127 , pp. 1677-1691
    • Liang, P.1    Lan, F.2    Lee, A.S.3
  • 21
    • 84867602223 scopus 로고    scopus 로고
    • Repolarization reserve determines drug responses in human pluripotent stem cell derived cardiomyocytes
    • Braam SR, Tertoolen L, Casini S, et al. Repolarization reserve determines drug responses in human pluripotent stem cell derived cardiomyocytes. Stem Cell Res 2013; 10:48-56.
    • (2013) Stem Cell Res , vol.10 , pp. 48-56
    • Braam, S.R.1    Tertoolen, L.2    Casini, S.3
  • 22
    • 84883791986 scopus 로고    scopus 로고
    • Screening drug-induced arrhythmia events using human induced pluripotent stem cell-derived cardiomyocytes and lowimpedance microelectrode arrays
    • Navarrete EG, Liang P, Lan F, et al. Screening drug-induced arrhythmia events using human induced pluripotent stem cell-derived cardiomyocytes and lowimpedance microelectrode arrays. Circulation 2013; 128 (11 Suppl 1):S3-S13.
    • (2013) Circulation , vol.128 , Issue.11 SUPPL. 1
    • Navarrete, E.G.1    Liang, P.2    Lan, F.3
  • 23
    • 84892752194 scopus 로고    scopus 로고
    • Small molecule-mediated directed differentiation of human embryonic stem cells toward ventricular cardiomyocytes
    • Karakikes I, Senyei GD, Hansen J, et al. Small molecule-mediated directed differentiation of human embryonic stem cells toward ventricular cardiomyocytes. Stem Cells Transl Med 2013; 3:18-31.
    • (2013) Stem Cells Transl Med , vol.3 , pp. 18-31
    • Karakikes, I.1    Senyei, G.D.2    Hansen, J.3
  • 24
    • 84878852415 scopus 로고    scopus 로고
    • Modeling human disease with pluripotent stem cells: From genome association to function
    • Merkle FT, Eggan K. Modeling human disease with pluripotent stem cells: from genome association to function. Cell Stem Cell 2013; 12:656-668.
    • (2013) Cell Stem Cell , vol.12 , pp. 656-668
    • Merkle, F.T.1    Eggan, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.