Increased afterload induces pathological cardiac hypertrophy: A new in vitro model

Basic Research in Cardiology

Volumn 107, Issue 6, 2012, Pages

  Hirt, Marc N ^a   Sörensen, Nils A ^a   Bartholdt, Lena M ^a   Boeddinghaus, Jasper ^a   Schaaf, Sebastian ^a   Eder, Alexandra ^a   Vollert, Ingra ^a   Stöhr, Andrea ^a   Schulze, Thomas ^a   Witten, Anika ^b   Stoll, Monika ^b   Hansen, Arne ^a   Eschenhagen, Thomas ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Afterload enhancement; Cardiac hypertrophy; Cardiac metabolism; Cardiac tissue engineering; Endothelin receptor antagonist; Fibrosis

Indexed keywords

COLLAGEN TYPE 1; ENDOTHELIN 1; MESSENGER RNA; PHENYLEPHRINE; ENDOTHELIN RECEPTOR;

ANIMAL CELL; ARTICLE; CARDIAC MUSCLE; CONTROLLED STUDY; ENGINEERED HEART TISSUE; GLUCOSE INTAKE; HEART AFTERLOAD; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE REMODELING; IN VITRO STUDY; MUSCLE CONTRACTILITY; MUSCLE RELAXATION; NONHUMAN; RAT; ANIMAL; BIOLOGICAL MODEL; CARDIOMEGALY; CELL CULTURE; DRUG ANTAGONISM; FIBROSIS; GENE EXPRESSION; GLYCOLYSIS; HEART MUSCLE CELL; LEWIS RAT; NEWBORN; PHYSIOLOGY; TISSUE ENGINEERING; WISTAR RAT;

ANIMALS; ANIMALS, NEWBORN; CARDIOMEGALY; CELLS, CULTURED; FIBROSIS; GENE EXPRESSION; GLYCOLYSIS; MODELS, BIOLOGICAL; MYOCYTES, CARDIAC; RATS; RATS, INBRED LEW; RATS, WISTAR; RECEPTORS, ENDOTHELIN; TISSUE ENGINEERING;

EID: 84867679523     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-012-0307-z     Document Type: Article

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