Frequency-dependent acceleration of relaxation involves decreased myofilament calcium sensitivity

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 292, Issue 5, 2007, Pages

  Varian, Kenneth D ^a   Janssen, Paul M L ^a,b  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

Calcium transient; Contractility; Diastolic dysfunction; Force frequency relationship; Rabbit

Indexed keywords

CALCIUM; FURA 2; MYOSIN LIGHT CHAIN; POTASSIUM; TROPONIN I;

ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CONTRACTURE; CONTROLLED STUDY; CORRELATION ANALYSIS; DESENSITIZATION; FORCE; FREQUENCY MODULATION; HEART CONTRACTION; HEART RATE; MALE; MUSCLE TWITCH; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; STATISTICAL ANALYSIS; STEADY STATE; ANIMAL; CELL CULTURE; DOSE RESPONSE; DRUG EFFECT; HEART MUSCLE CELL; MECHANICAL STRESS; METABOLISM; MICROFILAMENT; PHYSIOLOGY; RABBIT;

ANIMALS; CALCIUM; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; HEART RATE; MALE; MICROFILAMENTS; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; RABBITS; STRESS, MECHANICAL;

EID: 34250809531     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00778.2006     Document Type: Article

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