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Volumn 7, Issue 6, 2015, Pages 5020-5050

Mechanistic effects of calcitriol in cancer biology

Author keywords

Calcitriol; Cancer; Inflammation; Oncogenesis; Vitamin D deficiency

Indexed keywords

ANGIOPOIETIN 1; CALCITRIOL; CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 6; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR; PROGESTERONE RECEPTOR; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN P21; PROTEIN P27; REACTIVE OXYGEN METABOLITE; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UVOMORULIN; VASCULOTROPIN; ANTINEOPLASTIC AGENT;

EID: 84934938078     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu7065020     Document Type: Review
Times cited : (103)

References (209)
  • 1
    • 0028097038 scopus 로고
    • McCollum Award Lecture, 1994: Vitamin D—New horizons for the 21st century
    • Holick, M.F. McCollum Award Lecture, 1994: Vitamin D—New horizons for the 21st century. Am. J. Clin. Nutr. 1994, 60, 619-630.
    • (1994) Am. J. Clin. Nutr , Issue.60 , pp. 619-630
    • Holick, M.F.1
  • 2
  • 3
    • 0027236384 scopus 로고
    • Kinetic and thermodynamic studies of the conversion of previtamin D3 to vitamin D3 in human skin.
    • Tian, X.Q.; Chen, T.C.; Matsuoka, L.Y.; Wortsman, J.; Holick, M.F. Kinetic and thermodynamic studies of the conversion of previtamin D3 to vitamin D3 in human skin. J. Biol. Chem. 1993, 268, 14888-14892.
    • (1993) J. Biol. Chem , vol.268 , pp. 14888-14892
    • Tian, X.Q.1    Chen, T.C.2    Matsuoka, L.Y.3    Wortsman, J.4    Holick, M.F.5
  • 5
    • 34547208630 scopus 로고    scopus 로고
    • Expanding role for vitamin D in chronic kidney disease: Importance of blood 25-OH-D levels and extra-renal 1α-hydroxylase in the classical and nonclassical actions of 1α,25-dihydroxyvitamin D3
    • Jones, G. Expanding role for vitamin D in chronic kidney disease: Importance of blood 25-OH-D levels and extra-renal 1α-hydroxylase in the classical and nonclassical actions of 1α,25-dihydroxyvitamin D3. Semin. Dial. 2007, 20, 316-324.
    • (2007) Semin. Dial , vol.20 , pp. 316-324
    • Jones, G.1
  • 6
    • 0032943154 scopus 로고    scopus 로고
    • Regulation of vitamin D action
    • Brown, A.J. Regulation of vitamin D action. Nephrol. Dial. Transplant. 1999, 14, 11-16.
    • (1999) Nephrol. Dial. Transplant , vol.14 , pp. 11-16
    • Brown, A.J.1
  • 7
    • 78650876692 scopus 로고    scopus 로고
    • Vitamin D: Evolutionary, physiological and health perspectives
    • Holick, M.F. Vitamin D: Evolutionary, physiological and health perspectives. Curr. Drug Targets 2011, 12, 4-18.
    • (2011) Curr. Drug Targets , vol.12 , pp. 4-18
    • Holick, M.F.1
  • 8
    • 77956987565 scopus 로고    scopus 로고
    • The vitamin D and cancer conundrum: Aiming at a moving target
    • Toner, CD.; Davis, CD.; Milner, J.A. The vitamin D and cancer conundrum: Aiming at a moving target. J. Am. Diet. Assoc. 2010, 110, 1492-1500.
    • (2010) J. Am. Diet. Assoc , vol.110 , pp. 1492-1500
    • Toner, C.D.1    Davis, C.D.2    Milner, J.A.3
  • 10
    • 0032545486 scopus 로고    scopus 로고
    • The interaction of the vitamin D receptor with nuclear receptor corepressors and coactivators
    • Tagami, T.; Lutz, W.H.; Kumar, R.; Jameson, J.L. The interaction of the vitamin D receptor with nuclear receptor corepressors and coactivators. Biochem. Biophys. Res. Commun. 1998, 253, 358-363.
    • (1998) Biochem. Biophys. Res. Commun , vol.253 , pp. 358-363
    • Tagami, T.1    Lutz, W.H.2    Kumar, R.3    Jameson, J.L.4
  • 11
    • 84930335409 scopus 로고    scopus 로고
    • Health outcomes of vitamin D. Part II. Role in prevention of diseases
    • Wranicz, J.; Szostak-Wegierek, D. Health outcomes of vitamin D. Part II. Role in prevention of diseases. Rocz. Panstw. Zakl. Hig. 2014, 65, 273-279.
    • (2014) Rocz. Panstw. Zakl. Hig , vol.65 , pp. 273-279
    • Wranicz, J.1    Szostak-Wegierek, D.2
  • 12
    • 0029992392 scopus 로고    scopus 로고
    • Nongenomic regulation of protein kinase C isoforms by the vitamin D metabolites 1α,25-(OH)2 D3 and 24R,25-(OH)2 D3
    • Sylvia, V.L.; Schwartz, Z.; Ellis, E.B.; Helm, S.H.; Gomez, R.; Dean, D.D.; Boyan, B.D. Nongenomic regulation of protein kinase C isoforms by the vitamin D metabolites 1α,25-(OH)2 D3 and 24R,25-(OH)2 D3. J. Cell. Physiol. 1996, 167, 380-393.
    • (1996) J. Cell. Physiol. , vol.167 , pp. 380-393
    • Sylvia, V.L.1    Schwartz, Z.2    Ellis, E.B.3    Helm, S.H.4    Gomez, R.5    Dean, D.D.6    Boyan, B.D.7
  • 13
    • 0032005829 scopus 로고    scopus 로고
    • Studies suggesting the participation of protein kinase A in 1,25(OH)2-vitamin D3-dependent protein phosphorylation in cardiac muscle
    • Santillan, G.E.; Boland, R.L. Studies suggesting the participation of protein kinase A in 1,25(OH)2-vitamin D3-dependent protein phosphorylation in cardiac muscle. J. Mol. Cell. Cardiol. 1998, 30, 225-233.
    • (1998) J. Mol. Cell. Cardiol , vol.30 , pp. 225-233
    • Santillan, G.E.1    Boland, R.L.2
  • 14
    • 0028852112 scopus 로고
    • Modulation by 1,25(OH)2-vitamin D3 of the adenylyl cyclase/cyclic AMP pathway in rat and chick myoblasts
    • Vazquez, G.; Boland, R.; de Boland, A.R. Modulation by 1,25(OH)2-vitamin D3 of the adenylyl cyclase/cyclic AMP pathway in rat and chick myoblasts. Biochim. Biophys. Acta 1995, 1269, 91-97.
    • (1995) Biochim. Biophys. Acta , vol.1269 , pp. 91-97
    • Vazquez, G.1    Boland, R.2    Boland, D.A.3
  • 16
    • 0025323383 scopus 로고
    • 1,25(OH)2 vitamin D3 stimulates membrane phosphoinositide turnover, activates protein kinase C, and increases cytosolic calcium in rat colonic epithelium
    • Wali, R.K.; Baum, C.L.; Sitrin, M.D.; Brasitus, T.A. 1,25(OH)2 vitamin D3 stimulates membrane phosphoinositide turnover, activates protein kinase C, and increases cytosolic calcium in rat colonic epithelium. J. Clin. Investig. 1990, 85, 1296-1303.
    • (1990) J. Clin. Investig , vol.85 , pp. 1296-1303
    • Wali, R.K.1    Baum, C.L.2    Sitrin, M.D.3    Brasitus, T.A.4
  • 17
    • 0027459349 scopus 로고
    • Generation of inositol phosphates, diacylglycerol and calcium fluxes in myoblasts treated with 1,25-dihydroxyvitamin D3
    • Morelli, S.; de Boland, A.R.; Boland, R.L. Generation of inositol phosphates, diacylglycerol and calcium fluxes in myoblasts treated with 1,25-dihydroxyvitamin D3. Biochem. J. 1993, 289, 675-679.
    • (1993) Biochem. J. , vol.289 , pp. 675-679
    • Morelli, S.1    De Boland, A.R.2    Boland, R.L.3
  • 18
    • 0027464008 scopus 로고
    • Evidence for the participation of protein kinase C and 3′,5′-cyclic AMP-dependent protein kinase in the stimulation of muscle cell proliferation by 1,25-dihydroxy-vitamin D3
    • Bellido, T.; Morelli, S.; Fernandez, L.M.; Boland, R. Evidence for the participation of protein kinase C and 3′,5′-cyclic AMP-dependent protein kinase in the stimulation of muscle cell proliferation by 1,25-dihydroxy-vitamin D3. Mol. Cell. Endocrinol. 1993, 90, 231-238.
    • (1993) Mol. Cell. Endocrinol. , vol.90 , pp. 231-238
    • Bellido, T.1    Morelli, S.2    Fernandez, L.M.3    Boland, R.4
  • 19
    • 10044240701 scopus 로고    scopus 로고
    • Rapid, membrane-initiated actions of 1,25 dihydroxyvitamin D: What are they and what do they mean
    • Fleet, J.C. Rapid, membrane-initiated actions of 1,25 dihydroxyvitamin D: What are they and what do they mean? J. Nutr. 2004, 134, 3215-3218.
    • (2004) J. Nutr , vol.134 , pp. 3215-3218
    • Fleet, J.C.1
  • 20
    • 0035931993 scopus 로고    scopus 로고
    • The stimulation of MAP kinase by 1,25(OH)2-vitamin D3 in skeletal muscle cells is mediated by protein kinase C and calcium
    • Morelli, S.; Buitrago, C; Boland, R.; de Boland, A.R. The stimulation of MAP kinase by 1,25(OH)2-vitamin D3 in skeletal muscle cells is mediated by protein kinase C and calcium. Mol. Cell. Endocrinol. 2001, 173, 41-52.
    • (2001) Mol. Cell. Endocrinol , vol.173 , pp. 41-52
    • Morelli, S.1    Buitrago, C.2    Boland, R.3    De Boland, A.R.4
  • 21
    • 0027358897 scopus 로고
    • Stimulation of dihydropyridine-sensitive Ca2+ influx in cultured myoblasts by 1,25(OH)2-vitamin D3
    • Vazquez, G.; de Boland, A.R. Stimulation of dihydropyridine-sensitive Ca2+ influx in cultured myoblasts by 1,25(OH)2-vitamin D3. Biochem. Mol. Biol. Int. 1993, 31, 677-684.
    • (1993) Biochem. Mol. Biol. Int , vol.31 , pp. 677-684
    • Vazquez, G.1    De Boland, A.R.2
  • 23
    • 84908378402 scopus 로고    scopus 로고
    • Actions of 1,25(OH)2-vitamin D3 on the cellular cycle depend on VDR and p38 MAPK in skeletal muscle cells
    • Irazoqui, A.P.; Boland, R.L.; Buitrago, C.G. Actions of 1,25(OH)2-vitamin D3 on the cellular cycle depend on VDR and p38 MAPK in skeletal muscle cells. J. Mol. Endocrinol. 2014, 53, 331-343.
    • (2014) J. Mol. Endocrinol. , vol.53 , pp. 331-343
    • Irazoqui, A.P.1    Boland, R.L.2    Buitrago, C.G.3
  • 24
    • 84881130275 scopus 로고    scopus 로고
    • Role of VDR in 1α,25-dihydroxy vitamin D3-dependent non-genomic activation of MAPKs, Src and Akt in skeletal muscle cells
    • Buitrago, C; Pardo, V.G.; Boland, R. Role of VDR in 1α,25-dihydroxy vitamin D3-dependent non-genomic activation of MAPKs, Src and Akt in skeletal muscle cells. J. Steroid Biochem. Mol. Biol. 2013, 136, 125-130.
    • (2013) J. Steroid Biochem. Mol. Biol. , vol.136 , pp. 125-130
    • Buitrago, C.1    Pardo, V.G.2    Boland, R.3
  • 25
    • 0029849216 scopus 로고    scopus 로고
    • Functional assessment of two vitamin D-responsive elements in the rat 25-hydroxyvitamin D3 24-hydroxylase gene
    • Ohyama, Y.; Ozono, K.; Uchida, M.; Yoshimura, M.; Shinki, T.; Suda, T.; Yamamoto, O. Functional assessment of two vitamin D-responsive elements in the rat 25-hydroxyvitamin D3 24-hydroxylase gene. J. Biol. Chem. 1996, 271, 30381-30385.
    • (1996) J. Biol. Chem , vol.271 , pp. 30381-30385
    • Ohyama, Y.1    Ozono, K.2    Uchida, M.3    Yoshimura, M.4    Shinki, T.5    Suda, T.6    Yamamoto, O.7
  • 26
    • 0028945042 scopus 로고
    • Response elements function in the rat 1,25-dihydroxyvitamin D 24-hydroxylase promoter
    • Zierold, C; Darwish, H.M.; DeLuca, H.F. Two vitamin D response elements function in the rat 1,25-dihydroxyvitamin D 24-hydroxylase promoter. J. Biol. Chem. 1995, 270, 1675-1678.
    • (1995) J. Biol. Chem , vol.270 , pp. 1675-1678
    • Zierold, C.1    Darwish, H.M.2    Deluca, H.F.3    Two Vitamin, D.4
  • 27
    • 0034614617 scopus 로고    scopus 로고
    • Regulation of rat cytochrome P450C24 (CYP24) gene expression. Evidence for functional cooperation of Ras-activated Ets transcription factors with the vitamin D receptor in 1,25-dihydroxyvitamin D3-mediated induction
    • Dwivedi, P.P.; Omdahl, J.L.; Kola, I.; Hume, D.A.; May, B.K. Regulation of rat cytochrome P450C24 (CYP24) gene expression. Evidence for functional cooperation of Ras-activated Ets transcription factors with the vitamin D receptor in 1,25-dihydroxyvitamin D3-mediated induction. J. Biol. Chem. 2000, 275, 47-55.
    • (2000) J. Biol. Chem , vol.275 , pp. 47-55
    • Dwivedi, P.P.1    Omdahl, J.L.2    Kola, I.3    Hume, D.A.4    May, B.K.5
  • 28
    • 0037119412 scopus 로고    scopus 로고
    • Role of MAP kinases in the 1,25-dihydroxyvitamin D3-induced transactivation of the rat cytochrome P450C24 (CYP24) promoter. Specific functions for ERK1/ERK2 and ERK5
    • Dwivedi, P.P.; Hii, C.S.; Ferrante, A.; Tan, J.; Der, C.J.; Omdahl, J.L.; Morris, H.A.; May, B.K. Role of MAP kinases in the 1,25-dihydroxyvitamin D3-induced transactivation of the rat cytochrome P450C24 (CYP24) promoter. Specific functions for ERK1/ERK2 and ERK5. J. Biol. Chem. 2002, 277, 29643-29653.
    • (2002) J. Biol. Chem. , vol.277 , pp. 29643-29653
    • Dwivedi, P.P.1    Hii, C.S.2    Ferrante, A.3    Tan, J.4    Der, C.J.5    Omdahl, J.L.6    Morris, H.A.7    May, B.K.8
  • 29
    • 0027467511 scopus 로고
    • Effects of 1,25-dihydroxy vitamin D3 and phorbol ester on 25-hydroxyvitamin D3 24-hydroxylase cytochrome P450 messenger ribonucleic acid levels in primary cultures of rat renal cells
    • Chen, M.L.; Boltz, M.A.; Armbrecht, H.J. Effects of 1,25-dihydroxy vitamin D3 and phorbol ester on 25-hydroxyvitamin D3 24-hydroxylase cytochrome P450 messenger ribonucleic acid levels in primary cultures of rat renal cells. Endocrinology 1993, 132, 1782-1788.
    • (1993) Endocrinology , vol.132 , pp. 1782-1788
    • Chen, M.L.1    Boltz, M.A.2    Armbrecht, H.J.3
  • 30
    • 0027181823 scopus 로고
    • Phorbol ester markedly increases the sensitivity of intestinal epithelial cells to 1,25-dihydroxyvitamin D3
    • Armbrecht, H.J.; Hodam, T.L.; Boltz, M.A.; Chen, M.L. Phorbol ester markedly increases the sensitivity of intestinal epithelial cells to 1,25-dihydroxyvitamin D3. FEBS Lett. 1993, 327, 13–16.
    • (1993) FEBS Lett , vol.327 , pp. 13-16
    • Armbrecht, H.J.1    Hodam, T.L.2    Boltz, M.A.3    Chen, M.L.4
  • 31
    • 0028285896 scopus 로고
    • Is involved in 24-hydroxylase gene expression induced by 1,25(OH)2D3 in rat intestinal epithelial cells
    • Koyama, H.; Inaba, M.; Nishizawa, Y.; Ohno, S.; Morii, H. Protein kinase C is involved in 24-hydroxylase gene expression induced by 1,25(OH)2D3 in rat intestinal epithelial cells. J. Cell. Biochem. 1994, 55, 230–240.
    • (1994) J. Cell. Biochem , vol.55 , pp. 230-240
    • Koyama, H.1    Inaba, M.2    Nishizawa, Y.3    Ohno, S.4    Morii, H.5    Protein Kinase, C.6
  • 32
    • 23644453953 scopus 로고    scopus 로고
    • Molecular action of 1,25-dihydroxy vitamin D3 and phorbol ester on the activation of the rat cytochrome P450C24 (CYP24) promoter: Role of MAP kinase activities and identification of an important transcription factor binding site
    • Nutchey, B.K.; Kaplan, J.S.; Dwivedi, P.P.; Omdahl, J.L.; Ferrante, A.; May, B.K.; Hii, C.S. Molecular action of 1,25-dihydroxy vitamin D3 and phorbol ester on the activation of the rat cytochrome P450C24 (CYP24) promoter: Role of MAP kinase activities and identification of an important transcription factor binding site. Biochem. J. 2005, 389, 753–762.
    • (2005) Biochem. J. , vol.389 , pp. 753-762
    • Nutchey, B.K.1    Kaplan, J.S.2    Dwivedi, P.P.3    Omdahl, J.L.4    Ferrante, A.5    May, B.K.6    Hii, C.S.7
  • 33
    • 2342623470 scopus 로고    scopus 로고
    • Transrepression by a liganded nuclear receptor via a bHLH activator through co-regulator switching
    • Murayama, A.; Kim, M.S.; Yanagisawa, J.; Takeyama, K.; Kato, S. Transrepression by a liganded nuclear receptor via a bHLH activator through co-regulator switching. EMBO J. 2004, 23, 1598–1608.
    • (2004) EMBO J , vol.23 , pp. 1598-1608
    • Murayama, A.1    Kim, M.S.2    Yanagisawa, J.3    Takeyama, K.4    Kato, S.5
  • 35
    • 0015620751 scopus 로고
    • Stimulation of intestinal mucosal proliferation by vitamin D
    • Birge, S.J.; Alpers, D.H. Stimulation of intestinal mucosal proliferation by vitamin D. Gastroenterology 1973, 64, 977–982.
    • (1973) Gastroenterology , vol.64 , pp. 977-982
    • Birge, S.J.1    Alpers, D.H.2
  • 37
    • 84857716739 scopus 로고    scopus 로고
    • Multiple biological activities of lactic acid in cancer: Influences on tumor growth, angiogenesis and metastasis
    • Dhup, S.; Dadhich, R.K.; Porporato, P.E.; Sonveaux, P. Multiple biological activities of lactic acid in cancer: Influences on tumor growth, angiogenesis and metastasis. Curr. Pharm. Des. 2012, 18, 1319–1330.
    • (2012) Curr. Pharm. Des , vol.18 , pp. 1319-1330
    • Dhup, S.1    Dadhich, R.K.2    Porporato, P.E.3    Sonveaux, P.4
  • 38
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan, D.; Weinberg, R.A. Hallmarks of cancer: The next generation. Cell 2011, 144, 646–674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 39
    • 84935012263 scopus 로고    scopus 로고
    • Introduction to the molecular basis of cancer metabolism and the Warburg effect
    • Ngo, D.C.; Ververis, K.; Tortorella, S.M.; Karagiannis, T.C. Introduction to the molecular basis of cancer metabolism and the Warburg effect. Mol. Biol. Rep. 2015, 42, 819–823.
    • (2015) Mol. Biol. Rep. , vol.42 , pp. 819-823
    • Ngo, D.C.1    Ververis, K.2    Tortorella, S.M.3    Karagiannis, T.C.4
  • 40
    • 84858604270 scopus 로고    scopus 로고
    • Metabolic reprogramming: A cancer hallmark even warburg did not anticipate
    • Ward, P.S.; Thompson, C.B. Metabolic reprogramming: A cancer hallmark even warburg did not anticipate. Cancer Cell 2012, 21, 297–308.
    • (2012) Cancer Cell , vol.21 , pp. 297-308
    • Ward, P.S.1    Thompson, C.B.2
  • 41
    • 2942531063 scopus 로고    scopus 로고
    • Mitochondrial defects in cancer
    • Carew, J.S.; Huang, P. Mitochondrial defects in cancer. Mol. Cancer 2002, 1, 9.
    • (2002) Mol. Cancer , vol.1 , pp. 9
    • Carew, J.S.1    Huang, P.2
  • 42
    • 79955805773 scopus 로고    scopus 로고
    • Circulating levels of vitamin D and colon and rectal cancer: The Physicians’ Health Study and a meta-analysis of prospective studies
    • Lee, J.E.; Li, H.; Chan, A.T.; Hollis, B.W.; Lee, I.M.; Stampfer, M.J.; Wu, K.; Giovannucci, E.; Ma, J. Circulating levels of vitamin D and colon and rectal cancer: The Physicians’ Health Study and a meta-analysis of prospective studies. Cancer Prev. Res. (Phila) 2011, 4, 735–743.
    • (2011) Cancer Prev. Res. (Phila) , vol.4 , pp. 735-743
    • Lee, J.E.1    Li, H.2    Chan, A.T.3    Hollis, B.W.4    Lee, I.M.5    Stampfer, M.J.6    Wu, K.7    Giovannucci, E.8    Ma, J.9
  • 53
    • 84859212951 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • Forner, A.; Llovet, J.M.; Bruix, J. Hepatocellular carcinoma. Lancet 2012, 379, 1245–1255.
    • (2012) Lancet , vol.379 , pp. 1245-1255
    • Forner, A.1    Llovet, J.M.2    Bruix, J.3
  • 54
    • 33747830764 scopus 로고    scopus 로고
    • Hepatocellular carcinoma pathogenesis: From genes to environment
    • Farazi, P.A.; DePinho, R.A. Hepatocellular carcinoma pathogenesis: From genes to environment. Nat. Rev. Cancer 2006, 6, 674–687.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 674-687
    • Farazi, P.A.1    Depinho, R.A.2
  • 55
    • 0032924622 scopus 로고    scopus 로고
    • P16(INK4) is inactivated by extensive CpG methylation in human hepatocellular carcinoma
    • Matsuda, Y.; Ichida, T.; Matsuzawa, J.; Sugimura, K.; Asakura, H. p16(INK4) is inactivated by extensive CpG methylation in human hepatocellular carcinoma. Gastroenterology 1999, 116, 394–400.
    • (1999) Gastroenterology , vol.116 , pp. 394-400
    • Matsuda, Y.1    Ichida, T.2    Matsuzawa, J.3    Sugimura, K.4    Asakura, H.5
  • 56
    • 3543100257 scopus 로고    scopus 로고
    • Promoter hypermethylation silences cyclooxygenase-2 (Cox-2) and regulates growth of human hepatocellular carcinoma cells
    • Murata, H.; Tsuji, S.; Tsujii, M.; Sakaguchi, Y.; Fu, H.Y.; Kawano, S.; Hori, M. Promoter hypermethylation silences cyclooxygenase-2 (Cox-2) and regulates growth of human hepatocellular carcinoma cells. Lab. Investig. 2004, 84, 1050–1059.
    • (2004) Lab. Investig , vol.84 , pp. 1050-1059
    • Murata, H.1    Tsuji, S.2    Tsujii, M.3    Sakaguchi, Y.4    Fu, H.Y.5    Kawano, S.6    Hori, M.7
  • 60
    • 34250015299 scopus 로고    scopus 로고
    • Vitamin D and calcium supplementation reduces cancer risk: Results of a randomized trial
    • Lappe, J.M.; Travers-Gustafson, D.; Davies, K.M.; Recker, R.R.; Heaney, R.P. Vitamin D and calcium supplementation reduces cancer risk: Results of a randomized trial. Am. J. Clin. Nutr. 2007, 85, 1586–1591.
    • (2007) Am. J. Clin. Nutr , vol.85 , pp. 1586-1591
    • Lappe, J.M.1    Travers-Gustafson, D.2    Davies, K.M.3    Recker, R.R.4    Heaney, R.P.5
  • 64
    • 0026447217 scopus 로고
    • Geographic patterns of prostate cancer mortality. Evidence for a protective effect of ultraviolet radiation
    • Hanchette, C.L.; Schwartz, G.G. Geographic patterns of prostate cancer mortality. Evidence for a protective effect of ultraviolet radiation. Cancer 1992, 70, 2861–2869.
    • (1992) Cancer , vol.70 , pp. 2861-2869
    • Hanchette, C.L.1    Schwartz, G.G.2
  • 65
    • 0037086547 scopus 로고    scopus 로고
    • An estimate of premature cancer mortality in the U.S. due to inadequate doses of solar ultraviolet-B radiation
    • Grant, W.B. An estimate of premature cancer mortality in the U.S. due to inadequate doses of solar ultraviolet-B radiation. Cancer 2002, 94, 1867–1875.
    • (2002) Cancer , vol.94 , pp. 1867-1875
    • Grant, W.B.1
  • 66
    • 0035949122 scopus 로고    scopus 로고
    • Exposure to ultraviolet radiation: Association with susceptibility and age at presentation with prostate cancer
    • Luscombe, C.J.; Fryer, A.A.; French, M.E.; Liu, S.; Saxby, M.F.; Jones, P.W.; Strange, R.C. Exposure to ultraviolet radiation: Association with susceptibility and age at presentation with prostate cancer. Lancet 2001, 358, 641–642.
    • (2001) Lancet , vol.358 , pp. 641-642
    • Luscombe, C.J.1    Fryer, A.A.2    French, M.E.3    Liu, S.4    Saxby, M.F.5    Jones, P.W.6    Strange, R.C.7
  • 67
    • 0032920265 scopus 로고    scopus 로고
    • Vitamin D and breast cancer risk: The NHANES I Epidemiologic follow-up study, 1971–1975 to 1992. National Health and Nutrition Examination Survey. Cancer Epidemiol
    • John, E.M.; Schwartz, G.G.; Dreon, D.M.; Koo, J. Vitamin D and breast cancer risk: The NHANES I Epidemiologic follow-up study, 1971–1975 to 1992. National Health and Nutrition Examination Survey. Cancer Epidemiol. Biomark. Prev. 1999, 8, 399–406.
    • (1999) Biomark. Prev , vol.8 , pp. 399-406
    • John, E.M.1    Schwartz, G.G.2    Dreon, D.M.3    Koo, J.4
  • 69
    • 35148837103 scopus 로고    scopus 로고
    • Extrarenal vitamin D hydroxylase expression and activity in normal and malignant cells: Modification of expression by epigenetic mechanisms and dietary substances
    • Cross, H.S. Extrarenal vitamin D hydroxylase expression and activity in normal and malignant cells: Modification of expression by epigenetic mechanisms and dietary substances. Nutr. Rev. 2007, 65, S108–S112.
    • (2007) Nutr. Rev , vol.65 , pp. S108-S112
    • Cross, H.S.1
  • 71
    • 0019462379 scopus 로고
    • 1,25-dihydroxyvitamin D3 and malignant melanoma: The presence of receptors and inhibition of cell growth in culture
    • Colston, K.; Colston, M.J.; Feldman, D. 1,25-dihydroxyvitamin D3 and malignant melanoma: The presence of receptors and inhibition of cell growth in culture. Endocrinology 1981, 108, 1083–1086.
    • (1981) Endocrinology , vol.108 , pp. 1083-1086
    • Colston, K.1    Colston, M.J.2    Feldman, D.3
  • 72
    • 0028846176 scopus 로고
    • Inhibitors of cyclin-dependent kinase and cancer
    • Biggs, J.R.; Kraft, A.S. Inhibitors of cyclin-dependent kinase and cancer. J. Mol. Med. (Berl) 1995, 73, 509–514.
    • (1995) J. Mol. Med. (Berl) , vol.73 , pp. 509-514
    • Biggs, J.R.1    Kraft, A.S.2
  • 73
    • 0842287309 scopus 로고    scopus 로고
    • Molecular analysis of p21 promoter activity isolated from squamous carcinoma cell lines of the head and neck under the influence of 1,25(OH)2 vitamin D3 and its analogs
    • Hager, G.; Kornfehl, J.; Knerer, B.; Weigel, G.; Formanek, M. Molecular analysis of p21 promoter activity isolated from squamous carcinoma cell lines of the head and neck under the influence of 1,25(OH)2 vitamin D3 and its analogs. Acta Otolaryngol. 2004, 124, 90–96.
    • (2004) Acta Otolaryngol , vol.124 , pp. 90-96
    • Hager, G.1    Kornfehl, J.2    Knerer, B.3    Weigel, G.4    Formanek, M.5
  • 74
    • 32644451972 scopus 로고    scopus 로고
    • Regulation of the human p21(
    • Saramaki, A.; Banwell, C.M.; Campbell, M.J.; Carlberg, C. Regulation of the human p21(waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D3 receptor. Nucleic Acids Res. 2006, 34, 543–554.
    • (2006) Nucleic Acids Res , vol.34 , pp. 543-554
    • Saramaki, A.1    Banwell, C.M.2    Campbell, M.J.3    Carlberg, C.4
  • 75
    • 0030752754 scopus 로고    scopus 로고
    • Vitamin D analogues up-regulate p21 and p27 during growth inhibition of pancreatic cancer cell lines
    • Kawa, S.; Nikaido, T.; Aoki, Y.; Zhai, Y.; Kumagai, T.; Furihata, K.; Fujii, S.; Kiyosawa, K. Vitamin D analogues up-regulate p21 and p27 during growth inhibition of pancreatic cancer cell lines. Br. J. Cancer 1997, 76, 884-889.
    • (1997) Br. J. Cancer , vol.76 , pp. 884-889
    • Kawa, S.1    Nikaido, T.2    Aoki, Y.3    Zhai, Y.4    Kumagai, T.5    Furihata, K.6    Fujii, S.7    Kiyosawa, K.8
  • 76
    • 0030737494 scopus 로고    scopus 로고
    • Inhibition of proliferation of prostate cancer cells by a 19-nor-hexafluoride vitamin D3 analogue involves the induction of p21waf1, p27kip1 and E-cadherin
    • Campbell, M.J.; Elstner, E.; Holden, S.; Uskokovic, M.; Koeffler, H.P. Inhibition of proliferation of prostate cancer cells by a 19-nor-hexafluoride vitamin D3 analogue involves the induction of p21waf1, p27kip1 and E-cadherin. J. Mol. Endocrinol. 1997, 19, 15-27.
    • (1997) J. Mol. Endocrinol. , vol.19 , pp. 15-27
    • Campbell, M.J.1    Elstner, E.2    Holden, S.3    Uskokovic, M.4    Koeffler, H.P.5
  • 77
    • 76749119362 scopus 로고    scopus 로고
    • 1,25(OH)2vitamin D3 inhibits cell proliferation by promoting cell cycle arrest without inducing apoptosis and modifies cell morphology of mesenchymal multipotent cells
    • Artaza, J.N.; Sirad, F.; Ferrini, M.G.; Norris, K.C. 1,25(OH)2vitamin D3 inhibits cell proliferation by promoting cell cycle arrest without inducing apoptosis and modifies cell morphology of mesenchymal multipotent cells. J. Steroid Biochem. Mol. Biol. 2010, 119, 73-83.
    • (2010) J. Steroid Biochem. Mol. Biol , vol.119 , pp. 73-83
    • Artaza, J.N.1    Sirad, F.2    Ferrini, M.G.3    Norris, K.C.4
  • 79
    • 0030065422 scopus 로고    scopus 로고
    • Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937
    • Liu, M.; Lee, M.H.; Cohen, M.; Bommakanti, M.; Freedman, L.P. Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937. Genes Dev. 1996, 10, 142-153.
    • (1996) Genes Dev , vol.10 , pp. 142-153
    • Liu, M.1    Lee, M.H.2    Cohen, M.3    Bommakanti, M.4    Freedman, L.P.5
  • 80
    • 0033152196 scopus 로고    scopus 로고
    • 1,25-Dihydroxycholecalciferol (1,25-D3) inhibits the growth of squamous cell carcinoma and down-modulates p21(Waf1/Cip1) in vitro and in vivo
    • Hershberger, P.A.; Modzelewski, R.A.; Shurin, Z.R.; Rueger, R.M.; Trump, D.L.; Johnson, C.S. 1,25-Dihydroxycholecalciferol (1,25-D3) inhibits the growth of squamous cell carcinoma and down-modulates p21(Waf1/Cip1) in vitro and in vivo. Cancer Res. 1999, 59, 2644-2649.
    • (1999) Cancer Res , vol.59 , pp. 2644-2649
    • Hershberger, P.A.1    Modzelewski, R.A.2    Shurin, Z.R.3    Rueger, R.M.4    Trump, D.L.5    Johnson, C.S.6
  • 81
    • 0043236062 scopus 로고    scopus 로고
    • 1α,25-dihydroxyvitamin D3 (calcitriol) and its analogue, 19-nor-1α,25(OH)2D2, potentiate the effects of ionising radiation on human prostate cancer cells
    • Dunlap, N.; Schwartz, G.G.; Eads, D.; Cramer, S.D.; Sherk, A.B.; John, V.; Koumenis, C. 1α,25-dihydroxyvitamin D3 (calcitriol) and its analogue, 19-nor-1α,25(OH)2D2, potentiate the effects of ionising radiation on human prostate cancer cells. Br. J. Cancer 2003, 89, 746-753.
    • (2003) Br. J. Cancer , vol.89 , pp. 746-753
    • Dunlap, N.1    Schwartz, G.G.2    Eads, D.3    Cramer, S.D.4    Sherk, A.B.5    John, V.6    Koumenis, C.7
  • 82
    • 0036689119 scopus 로고    scopus 로고
    • Cisplatin potentiates 1,25-dihydroxyvitamin D3-induced apoptosis in association with increased mitogen-activated protein kinase kinase kinase 1 (MEKK-1) expression
    • Hershberger, P.A.; McGuire, T.F.; Yu, W.D.; Zuhowski, E.G.; Schellens, J.H.; Egorin, M.J.; Trump, D.L.; Johnson, C.S. Cisplatin potentiates 1,25-dihydroxyvitamin D3-induced apoptosis in association with increased mitogen-activated protein kinase kinase kinase 1 (MEKK-1) expression. Mol. Cancer Ther. 2002, 1, 821-829.
    • (2002) Mol. Cancer Ther , vol.1 , pp. 821-829
    • Hershberger, P.A.1    McGuire, T.F.2    Yu, W.D.3    Zuhowski, E.G.4    Schellens, J.H.5    Egorin, M.J.6    Trump, D.L.7    Johnson, C.S.8
  • 83
    • 54049152433 scopus 로고    scopus 로고
    • 1α,25-Dihydroxyvitamin D3 potentiates cisplatin antitumor activity by p73 induction in a squamous cell carcinoma model
    • Ma, Y.; Yu, W.D.; Hershberger, P.A.; Flynn, G.; Kong, R.X.; Trump, D.L.; Johnson, C.S. 1α,25-Dihydroxyvitamin D3 potentiates cisplatin antitumor activity by p73 induction in a squamous cell carcinoma model. Mol. Cancer Ther. 2008, 7, 3047-3055.
    • (2008) Mol. Cancer Ther , vol.7 , pp. 3047-3055
    • Ma, Y.1    Yu, W.D.2    Hershberger, P.A.3    Flynn, G.4    Kong, R.X.5    Trump, D.L.6    Johnson, C.S.7
  • 84
    • 0036075032 scopus 로고    scopus 로고
    • Calcitriol (1,25-dihydroxycholecalciferol) potentiates activity of mitoxantrone/dexamethasone in an androgen independent prostate cancer model
    • Ahmed, S.; Johnson, C.S.; Rueger, R.M.; Trump, D.L. Calcitriol (1,25-dihydroxycholecalciferol) potentiates activity of mitoxantrone/dexamethasone in an androgen independent prostate cancer model. J. Urol. 2002, 168, 756-761.
    • (2002) J. Urol , vol.168 , pp. 756-761
    • Ahmed, S.1    Johnson, C.S.2    Rueger, R.M.3    Trump, D.L.4
  • 85
    • 0034896572 scopus 로고    scopus 로고
    • Calcitriol (1,25-dihydroxycholecalciferol) enhances paclitaxel antitumor activity in vitro and in vivo and accelerates paclitaxel-induced apoptosis
    • Hershberger, P.A.; Yu, W.D.; Modzelewski, R.A.; Rueger, R.M.; Johnson, C.S.; Trump, D.L. Calcitriol (1,25-dihydroxycholecalciferol) enhances paclitaxel antitumor activity in vitro and in vivo and accelerates paclitaxel-induced apoptosis. Clin. Cancer Res. 2001, 7, 1043-1051.
    • (2001) Clin. Cancer Res , vol.7 , pp. 1043-1051
    • Hershberger, P.A.1    Yu, W.D.2    Modzelewski, R.A.3    Rueger, R.M.4    Johnson, C.S.5    Trump, D.L.6
  • 87
    • 0034687341 scopus 로고    scopus 로고
    • The anti-proliferative effects of 1α,25(OH)2D3 on breast and prostate cancer cells are associated with induction of BRCA1 gene expression
    • Campbell, M.J.; Gombart, A.F.; Kwok, S.H.; Park, S.; Koeffler, H.P. The anti-proliferative effects of 1α,25(OH)2D3 on breast and prostate cancer cells are associated with induction of BRCA1 gene expression. Oncogene 2000, 19, 5091-5097.
    • (2000) Oncogene , vol.19 , pp. 5091-5097
    • Campbell, M.J.1    Gombart, A.F.2    Kwok, S.H.3    Park, S.4    Koeffler, H.P.5
  • 90
    • 0029049917 scopus 로고
    • 1,25-Dihydroxyvitamin D3 suppresses cell growth, DNA synthesis, and phosphorylation of retinoblastoma protein in a breast cancer cell line
    • Fan, F.S.; Yu, W.C. 1,25-Dihydroxyvitamin D3 suppresses cell growth, DNA synthesis, and phosphorylation of retinoblastoma protein in a breast cancer cell line. Cancer Investig. 1995, 13, 280-286.
    • (1995) Cancer Investig , vol.13 , pp. 280-286
    • Fan, F.S.1    Yu, W.C.2
  • 91
    • 0034742488 scopus 로고    scopus 로고
    • Inhibitory effects of 1α,25-dihydroxyvitamin D3 on the G1-S phase-controlling machinery
    • Jensen, S.S.; Madsen, M.W.; Lukas, J.; Binderup, L.; Bartek, J. Inhibitory effects of 1α,25-dihydroxyvitamin D3 on the G1-S phase-controlling machinery. Mol. Endocrinol. 2001, 15, 1370-1380.
    • (2001) Mol. Endocrinol , vol.15 , pp. 1370-1380
    • Jensen, S.S.1    Madsen, M.W.2    Lukas, J.3    Binderup, L.4    Bartek, J.5
  • 93
    • 33644805351 scopus 로고    scopus 로고
    • The epidemiology of vitamin D and colorectal cancer: Recent findings
    • Giovannucci, E. The epidemiology of vitamin D and colorectal cancer: Recent findings. Curr. Opin. Gastroenterol. 2006, 22, 24-29.
    • (2006) Curr. Opin. Gastroenterol , vol.22 , pp. 24-29
    • Giovannucci, E.1
  • 97
    • 0034463114 scopus 로고    scopus 로고
    • Calcitriol-induced apoptosis in LNCaP cells is blocked by overexpression of Bcl-2
    • Blutt, S.E.; McDonnell, T.J.; Polek, T.C.; Weigel, N.L. Calcitriol-induced apoptosis in LNCaP cells is blocked by overexpression of Bcl-2. Endocrinology 2000, 141, 10-17.
    • (2000) Endocrinology , vol.141 , pp. 10-17
    • Blutt, S.E.1    McDonnell, T.J.2    Polek, T.C.3    Weigel, N.L.4
  • 98
    • 0036634939 scopus 로고    scopus 로고
    • Apoptosis induction by 1α,25-dihydroxyvitamin D3 in prostate cancer
    • Guzey, M.; Kitada, S.; Reed, J.C. Apoptosis induction by 1α,25-dihydroxyvitamin D3 in prostate cancer. Mol. Cancer Ther. 2002, 1, 667-677.
    • (2002) Mol. Cancer Ther , vol.1 , pp. 667-677
    • Guzey, M.1    Kitada, S.2    Reed, J.C.3
  • 99
    • 0038772000 scopus 로고    scopus 로고
    • 1,25-dihydroxyvitamin D3-induced apoptosis of retinoblastoma cells is associated with reciprocal changes of Bcl-2 and bax
    • Wagner, N.; Wagner, K.D.; Schley, G.; Badiali, L.; Theres, H.; Scholz, H. 1,25-dihydroxyvitamin D3-induced apoptosis of retinoblastoma cells is associated with reciprocal changes of Bcl-2 and bax. Exp. Eye Res. 2003, 77, 1-9.
    • (2003) Exp. Eye Res , vol.77 , pp. 1-9
    • Wagner, N.1    Wagner, K.D.2    Schley, G.3    Badiali, L.4    Theres, H.5    Scholz, H.6
  • 100
    • 71349088729 scopus 로고    scopus 로고
    • Treatment of K562 cells with 1,25-dihydroxyvitamin D3 induces distinct alterations in the expression of apoptosis-related genes BCL2, BAX, BCLxl, and p21
    • Kizildag, S.; Ates, H. Treatment of K562 cells with 1,25-dihydroxyvitamin D3 induces distinct alterations in the expression of apoptosis-related genes BCL2, BAX, BCLxl, and p21. Ann. Hematol. 2009, 89, 1-7.
    • (2009) Ann. Hematol , vol.89 , pp. 1-7
    • Kizildag, S.1    Ates, H.2
  • 101
    • 77956831569 scopus 로고    scopus 로고
    • Calcitriol enhances gemcitabine anti-tumor activity in vitro and in vivo by promoting apoptosis in a human pancreatic carcinoma model system
    • Yu, W.D.; Ma, Y.; Flynn, G.; Muindi, J.R.; Kong, R.X.; Trump, D.L.; Johnson, C.S. Calcitriol enhances gemcitabine anti-tumor activity in vitro and in vivo by promoting apoptosis in a human pancreatic carcinoma model system. Cell Cycle 2010, 9, 3022-3029.
    • (2010) Cell Cycle , vol.9 , pp. 3022-3029
    • Yu, W.D.1    Ma, Y.2    Flynn, G.3    Muindi, J.R.4    Kong, R.X.5    Trump, D.L.6    Johnson, C.S.7
  • 102
    • 0035854680 scopus 로고    scopus 로고
    • Vitamin D3-induced apoptosis of murine squamous cell carcinoma cells. Selective induction of caspase-dependent MEK cleavage and up-regulation of MEKK-1
    • McGuire, T.F.; Trump, D.L.; Johnson, C.S. Vitamin D3-induced apoptosis of murine squamous cell carcinoma cells. Selective induction of caspase-dependent MEK cleavage and up-regulation of MEKK-1. J. Biol. Chem. 2001, 276, 26365-26373.
    • (2001) J. Biol. Chem , vol.276 , pp. 26365-26373
    • McGuire, T.F.1    Trump, D.L.2    Johnson, C.S.3
  • 103
    • 27544515088 scopus 로고    scopus 로고
    • Calcium signaling in cancer and vitamin D
    • Sergeev, I.N. Calcium signaling in cancer and vitamin D. J. Steroid Biochem. Mol. Biol. 2005, 97, 145-151.
    • (2005) J. Steroid Biochem. Mol. Biol , vol.97 , pp. 145-151
    • Sergeev, I.N.1
  • 104
    • 20444479080 scopus 로고    scopus 로고
    • Sensitizesbreast cancer cells to the action of H2O2: Mitochondria as a convergence point in the death pathway
    • Weitsman, G.E.; Koren, R.; Zuck, E.; Rotem, C; Liberman, U.A.; Ravid, A. Vitamin D sensitizes breast cancer cells to the action of H2O2: Mitochondria as a convergence point in the death pathway. Free Radic. Biol. Med. 2005, 39, 266-278.
    • (2005) Free Radic. Biol. Med , vol.39 , pp. 266-278
    • Weitsman, G.E.1    Koren, R.2    Zuck, E.3    Rotem, C.4    Liberman, U.A.5    Ravid, A.6    Vitamin, D.7
  • 105
    • 0642367254 scopus 로고    scopus 로고
    • The role of reactive oxygen species in the anticancer activity of vitamin D
    • Ravid, A.; Koren, R. The role of reactive oxygen species in the anticancer activity of vitamin D. Recent Results Cancer Res. 2003, 164, 357-367.
    • (2003) Recent Results Cancer Res , vol.164 , pp. 357-367
    • Ravid, A.1    Koren, R.2
  • 107
    • 0031010342 scopus 로고    scopus 로고
    • Survey of telomerase activity in human cancer
    • Shay, J.W.; Bacchetti, S. A survey of telomerase activity in human cancer. Eur. J. Cancer 1997, 33, 787-791.
    • (1997) Eur. J. Cancer , vol.33 , pp. 787-791
    • Shay, J.W.1    Bacchetti, S.A.2
  • 108
    • 1842868727 scopus 로고    scopus 로고
    • Combination treatment with 1α,25-dihydroxyvitamin D3 and 9-cis-retinoic acid directly inhibits human telomerase reverse transcriptase transcription in prostate cancer cells
    • Ikeda, N; Uemura, H.; Ishiguro, H.; Hori, M.; Hosaka, M.; Kyo, S.; Miyamoto, K.; Takeda, E.; Kubota, Y. Combination treatment with 1α,25-dihydroxyvitamin D3 and 9-cis-retinoic acid directly inhibits human telomerase reverse transcriptase transcription in prostate cancer cells. Mol. Cancer Ther. 2003, 2, 739-746.
    • (2003) Mol. Cancer Ther , vol.2 , pp. 739-746
    • Ikeda, N.1    Uemura, H.2    Ishiguro, H.3    Hori, M.4    Hosaka, M.5    Kyo, S.6    Miyamoto, K.7    Takeda, E.8    Kubota, Y.9
  • 113
    • 66449120903 scopus 로고    scopus 로고
    • 1α,25-dihydroxyvitamin D3 reduces c-Myc expression, inhibiting proliferation and causing G1 accumulation in C4-2 prostate cancer cells
    • Rohan, J.N.; Weigel, N.L. 1α,25-dihydroxyvitamin D3 reduces c-Myc expression, inhibiting proliferation and causing G1 accumulation in C4-2 prostate cancer cells. Endocrinology 2009, 150, 2046-2054.
    • (2009) Endocrinology , vol.150 , pp. 2046-2054
    • Rohan, J.N.1    Weigel, N.L.2
  • 115
    • 19644376774 scopus 로고    scopus 로고
    • Tumor dormancy and MYC inactivation: Pushing cancer to the brink
    • Shachaf, CM.; Felsher, D.W. Tumor dormancy and MYC inactivation: Pushing cancer to the brink of normalcy. Cancer Res. 2005, 65, 4471-4474.
    • (2005) Cancer Res , vol.65 , pp. 4471-4474
    • Shachaf, C.M.1    Felsher, D.W.2
  • 117
    • 84855225831 scopus 로고    scopus 로고
    • VDR/RXR and TCF4/β-catenin cistromes in colonic cells of colorectal tumor origin: Impact on c-FOS and c-MYC gene expression
    • Meyer, M.B.; Goetsch, P.D.; Pike, J.W. VDR/RXR and TCF4/β-catenin cistromes in colonic cells of colorectal tumor origin: Impact on c-FOS and c-MYC gene expression. Mol. Endocrinol. 2011, 26, 37-51.
    • (2011) Mol. Endocrinol , vol.26 , pp. 37-51
    • Meyer, M.B.1    Goetsch, P.D.2    Pike, J.W.3
  • 118
    • 0030032309 scopus 로고    scopus 로고
    • A composite element binding the vitamin D receptor, retinoid X receptor α, and a member of the CTF/NF-1 family of transcription factors mediates the vitamin D responsiveness of the c-fos promoter
    • Candeliere, G.A.; Jurutka, P.W.; Haussler, M.R.; St-Arnaud, R. A composite element binding the vitamin D receptor, retinoid X receptor α, and a member of the CTF/NF-1 family of transcription factors mediates the vitamin D responsiveness of the c-fos promoter. Mol. Cell. Biol. 1996, 16, 584-592.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 584-592
    • Candeliere, G.A.1    Jurutka, P.W.2    Haussler, M.R.3    St-Arnaud, R.4
  • 120
    • 32244436422 scopus 로고    scopus 로고
    • Ether à go-go potassium channels and cancer
    • Camacho, J. Ether à go-go potassium channels and cancer. Cancer Lett. 2006, 233, 1-9.
    • (2006) Cancer Lett , vol.233 , pp. 1-9
    • Camacho, J.1
  • 125
    • 0242331613 scopus 로고    scopus 로고
    • Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy
    • Bocci, G.; Francia, G.; Man, S.; Lawler, J.; Kerbel, R.S. Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy. Proc. Natl. Acad. Sci. USA 2003, 100, 12917-12922.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 12917-12922
    • Bocci, G.1    Francia, G.2    Man, S.3    Lawler, J.4    Kerbel, R.S.5
  • 126
    • 84938095333 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) inhibition—A critical review
    • Moreira, I.S.; Fernandes, P.A.; Ramos, M.J. Vascular endothelial growth factor (VEGF) inhibition—A critical review. Anticancer Agents Med. Chem. 2007, 7, 223-245.
    • (2007) Anticancer Agents Med. Chem , vol.7 , pp. 223-245
    • Moreira, I.S.1    Fernandes, P.A.2    Ramos, M.J.3
  • 127
    • 85047685002 scopus 로고    scopus 로고
    • Antiproliferative effects of 1α,25-dihydroxyvitamin D3 and vitamin D analogs on tumor-derived endothelial cells
    • Bernardi, R.J.; Johnson, C.S.; Modzelewski, R.A.; Trump, D.L. Antiproliferative effects of 1α,25-dihydroxyvitamin D3 and vitamin D analogs on tumor-derived endothelial cells. Endocrinology 2002, 143, 2508-2514.
    • (2002) Endocrinology , vol.143 , pp. 2508-2514
    • Bernardi, R.J.1    Johnson, C.S.2    Modzelewski, R.A.3    Trump, D.L.4
  • 128
    • 59149094862 scopus 로고    scopus 로고
    • Role of vitamin D receptor in the antiproliferative effects of calcitriol in tumor-derived endothelial cells and tumor angiogenesis in vivo
    • Chung, I.; Han, G.; Seshadri, M.; Gillard, B.M.; Yu, W.D.; Foster, B.A.; Trump, D.L.; Johnson, C.S. Role of vitamin D receptor in the antiproliferative effects of calcitriol in tumor-derived endothelial cells and tumor angiogenesis in vivo. Cancer Res. 2009, 69, 967-975.
    • (2009) Cancer Res , vol.69 , pp. 967-975
    • Chung, I.1    Han, G.2    Seshadri, M.3    Gillard, B.M.4    Yu, W.D.5    Foster, B.A.6    Trump, D.L.7    Johnson, C.S.8
  • 129
    • 0033870768 scopus 로고    scopus 로고
    • 1α,25-dihydroxyvitamin D3 inhibits angiogenesis in vitro and in vivo
    • Mantell, D.J.; Owens, P.E.; Bundred, N.J.; Mawer, E.B.; Canfield, A.E. 1α,25-dihydroxyvitamin D3 inhibits angiogenesis in vitro and in vivo. Circ. Res. 2000, 87, 214-220.
    • (2000) Circ. Res , vol.87 , pp. 214-220
    • Mantell, D.J.1    Owens, P.E.2    Bundred, N.J.3    Mawer, E.B.4    Canfield, A.E.5
  • 131
    • 0032906744 scopus 로고    scopus 로고
    • Inhibition of angiogenesis as a mechanism for inhibition by lα-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 of colon carcinogenesis induced by azoxymethane in Wistar rats
    • Iseki, K.; Tatsuta, M.; Uehara, H.; Iishi, H.; Yano, H.; Sakai, N.; Ishiguro, S. Inhibition of angiogenesis as a mechanism for inhibition by lα-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 of colon carcinogenesis induced by azoxymethane in Wistar rats. Int. J. Cancer 1999, 81, 730-733.
    • (1999) Int. J. Cancer , vol.81 , pp. 730-733
    • Iseki, K.1    Tatsuta, M.2    Uehara, H.3    Iishi, H.4    Yano, H.5    Sakai, N.6    Ishiguro, S.7
  • 133
    • 4444352196 scopus 로고    scopus 로고
    • 1α,25-dihydroxycholecalciferol increases the expression of vascular endothelial growth factor in C3H10T1/2 mouse embryo fibroblasts
    • Levine, M.J.; Teegarden, D. 1α,25-dihydroxycholecalciferol increases the expression of vascular endothelial growth factor in C3H10T1/2 mouse embryo fibroblasts. J. Nutr. 2004, 134, 2244-2250.
    • (2004) J. Nutr , vol.134 , pp. 2244-2250
    • Levine, M.J.1    Teegarden, D.2
  • 134
    • 0036708149 scopus 로고    scopus 로고
    • 1Α,25-dihydroxyvitamin D3 promotes vascularization of the chondro-osseous junction by stimulating expression of vascular endothelial growth factor and matrix metalloproteinase 9
    • Lin, R.; Amizuka, N.; Sasaki, T.; Aarts, M.M.; Ozawa, H.; Goltzman, D.; Henderson, J.E.; White, J.H. 1Α,25-dihydroxyvitamin D3 promotes vascularization of the chondro-osseous junction by stimulating expression of vascular endothelial growth factor and matrix metalloproteinase 9. J. Bone Miner. Res. 2002, 17, 1604-1612.
    • (2002) J. Bone Miner. Res , vol.17 , pp. 1604-1612
    • Lin, R.1    Amizuka, N.2    Sasaki, T.3    Aarts, M.M.4    Ozawa, H.5    Goltzman, D.6    Henderson, J.E.7    White, J.H.8
  • 137
    • 33646156641 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 stimulates vascular smooth muscle cell proliferation through a VEGF-mediated pathway
    • Cardus, A.; Parisi, E.; Gallego, C; Aldea, M.; Fernandez, E.; Valdivielso, J.M. 1,25-Dihydroxyvitamin D3 stimulates vascular smooth muscle cell proliferation through a VEGF-mediated pathway. Kidney Int. 2006, 69, 1377-1384.
    • (2006) Kidney Int , vol.69 , pp. 1377-1384
    • Cardus, A.1    Parisi, E.2    Gallego, C.3    Aldea, M.4    Fernandez, E.5    Valdivielso, J.M.6
  • 139
    • 0036379695 scopus 로고    scopus 로고
    • Vitamin D receptor-dependent antitumour effects of 1,25-dihydroxyvitamin D3 and two synthetic analogues in three in vivo models of prostate cancer
    • Oades, G.M.; Dredge, K.; Kirby, R.S.; Colston, K.W. Vitamin D receptor-dependent antitumour effects of 1,25-dihydroxyvitamin D3 and two synthetic analogues in three in vivo models of prostate cancer. BJU Int. 2002, 90, 607-616.
    • (2002) BJU Int , vol.90 , pp. 607-616
    • Oades, G.M.1    Dredge, K.2    Kirby, R.S.3    Colston, K.W.4
  • 141
    • 0036478799 scopus 로고    scopus 로고
    • 1,25-dihydroxyvitamin D3 stimulates vascular endothelial growth factor release in aortic smooth muscle cells: Role of p38 mitogen-activated protein kinase
    • Yamamoto, T.; Kozawa, O.; Tanabe, K.; Akamatsu, S.; Matsuno, H.; Dohi, S.; Hirose, H.; Uematsu, T. 1,25-dihydroxyvitamin D3 stimulates vascular endothelial growth factor release in aortic smooth muscle cells: Role of p38 mitogen-activated protein kinase. Arch. Biochem. Biophys. 2002, 398, 1-6.
    • (2002) Arch. Biochem. Biophys. , vol.398 , pp. 1-6
    • Yamamoto, T.1    Kozawa, O.2    Tanabe, K.3    Akamatsu, S.4    Matsuno, H.5    Dohi, S.6    Hirose, H.7    Uematsu, T.8
  • 142
    • 84908217408 scopus 로고    scopus 로고
    • The role of dietary histone deacetylases (HDACs) inhibitors in health and disease
    • Bassett, S.A.; Barnett, M.P. The role of dietary histone deacetylases (HDACs) inhibitors in health and disease. Nutrients 2014, 6, 4273-4301.
    • (2014) Nutrients , vol.6 , pp. 4273-4301
    • Bassett, S.A.1    Barnett, M.P.2
  • 143
    • 84926341508 scopus 로고    scopus 로고
    • HDAC1 overexpression independently predicts biochemical recurrence and is associated with rapid tumor cell proliferation and genomic instability in prostate cancer
    • Burdelski, C; Ruge, O.M.; Melling, N.; Koop, C; Simon, R.; Steurer, S.; Sauter, G.; Kluth, M.; Hube-Magg, C; Minner, S. et al. HDAC1 overexpression independently predicts biochemical recurrence and is associated with rapid tumor cell proliferation and genomic instability in prostate cancer. Exp. Mol. Pathol. 2015, 98, 419-426.
    • (2015) Exp. Mol. Pathol. , vol.98 , pp. 419-426
    • Burdelski, C.1    Ruge, O.M.2    Melling, N.3    Koop, C.4    Simon, R.5    Steurer, S.6    Sauter, G.7    Kluth, M.8    Hube-Magg, C.9    Minner, S.10
  • 144
    • 84883423841 scopus 로고    scopus 로고
    • The HDAC inhibitor LBH589 induces ERK-dependent prometaphase arrest in prostate cancer via HDAC6 inactivation and down-regulation
    • Chuang, M.J.; Wu, S.T.; Tang, S.H.; Lai, X.M.; Lai, H.C.; Hsu, K.H.; Sun, K.H.; Sun, G.H.; Chang, S.Y.; Yu, D.S.; et al. The HDAC inhibitor LBH589 induces ERK-dependent prometaphase arrest in prostate cancer via HDAC6 inactivation and down-regulation. PLoS ONE 2013, 8, e73401.
    • (2013) Plos ONE , vol.8
    • Chuang, M.J.1    Wu, S.T.2    Tang, S.H.3    Lai, X.M.4    Lai, H.C.5    Hsu, K.H.6    Sun, K.H.7    Sun, G.H.8    Chang, S.Y.9    Yu, D.S.10
  • 147
    • 85206205849 scopus 로고    scopus 로고
    • Combined histone deacetylase inhibition
    • Raha, P.; Thomas, S.; Thurn, K.T.; Park, J.; Munster, P.N. Combined histone deacetylase inhibition and tamoxifen induces apoptosis in tamoxifen resistant breast cancer models, by reversing Bcl-2 overexpression. Breast Cancer Res. BCR 2015, 17, 533.
    • (2015) Breast Cancer Res. BCR , vol.17 , pp. 533
    • Raha, P.1    Thomas, S.2    Thurn, K.T.3    Park, J.4    Munster, P.N.5
  • 148
    • 84918826968 scopus 로고    scopus 로고
    • Activation of the intrinsic apoptosis pathway contributes to the induction of apoptosis in hepatocellular carcinoma cells by valproic acid
    • Yang, W.; Zhao, X.; Pei, F.; Ji, M.; Ma, W.; Wang, Y.; Jiang, G. Activation of the intrinsic apoptosis pathway contributes to the induction of apoptosis in hepatocellular carcinoma cells by valproic acid. Oncol. Lett. 2015, 9, 881-886.
    • (2015) Oncol. Lett , vol.9 , pp. 881-886
    • Yang, W.1    Zhao, X.2    Pei, F.3    Ji, M.4    Ma, W.5    Wang, Y.6    Jiang, G.7
  • 149
    • 84928695655 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors repress chondrosarcoma cell proliferation
    • Zhu, J.; Gu, J.; Ma, J.; Xu, Z.; Tao, H. Histone deacetylase inhibitors repress chondrosarcoma cell proliferation. J. BUON 2015, 20, 269-274.
    • (2015) J. BUON , vol.20 , pp. 269-274
    • Zhu, J.1    Gu, J.2    Ma, J.3    Xu, Z.4    Tao, H.5
  • 150
    • 84949322531 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors prevent activation-induced cell death and promote anti-tumor immunity
    • Cao, K.; Wang, G.; Li, W.; Zhang, L.; Wang, R.; Huang, Y.; Du, L.; Jiang, J.; Wu, C; He, X. et al. Histone deacetylase inhibitors prevent activation-induced cell death and promote anti-tumor immunity. Oncogene 2015, doi:10.1038/onc.2015.46.
    • (2015) Oncogene
    • Cao, K.1    Wang, G.2    Li, W.3    Zhang, L.4    Wang, R.5    Huang, Y.6    Du, L.7    Jiang, J.8    Wu, C.9    He, X.10
  • 151
    • 80051622767 scopus 로고    scopus 로고
    • Impact of vitamin D metabolism on clinical epigenetics. Clin
    • Karlic, H.; Varga, F. Impact of vitamin D metabolism on clinical epigenetics. Clin. Epigenetics 2011, 2, 55-61.
    • (2011) Epigenetics , vol.2 , pp. 55-61
    • Karlic, H.1    Varga, F.2
  • 152
    • 84888873567 scopus 로고    scopus 로고
    • Vitamin D and chronic obstructive pulmonary
    • Janssens, W.; Decramer, M.; Mathieu, C; Korf, H. Vitamin D and chronic obstructive pulmonary disease: Hype or reality? Lancet Respir. Med. 2013, 1, 804-812.
    • (2013) Med , vol.1 , pp. 804-812
    • Janssens, W.1    Decramer, M.2    Mathieu, C.3    Korf, H.4
  • 154
    • 0035810045 scopus 로고    scopus 로고
    • Synergistic growth inhibition of prostate cancer cells by la,25 Dihydroxyvitamin D3 and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A
    • Rashid, S.F.; Moore, J.S.; Walker, E.; Driver, P.M.; Engel, J.; Edwards, C.E.; Brown, G.; Uskokovic, M.R.; Campbell, M.J. Synergistic growth inhibition of prostate cancer cells by la,25 Dihydroxyvitamin D3 and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A. Oncogene 2001, 20, 1860-1872.
    • (2001) Oncogene , vol.20 , pp. 1860-1872
    • Rashid, S.F.1    Moore, J.S.2    Walker, E.3    Driver, P.M.4    Engel, J.5    Edwards, C.E.6    Brown, G.7    Uskokovic, M.R.8    Campbell, M.J.9
  • 156
    • 65549121213 scopus 로고    scopus 로고
    • Cyclical chromatin
    • Saramaki, A.; Diermeier, S.; Kellner, R.; Laitinen, H.; Vaisanen, S.; Carlberg, C. Cyclical chromatin looping and transcription factor association on the regulatory regions of the p21 (CDKN1A) gene in response to 1α,25-dihydroxyvitamin D3. J. Biol. Chem. 2009, 284, 8073-8082.
    • (2009) J. Biol. Chem , vol.284 , pp. 8073-8082
    • Saramaki, A.1    Diermeier, S.2    Kellner, R.3    Laitinen, H.4    Vaisanen, S.5    Carlberg, C.6
  • 158
    • 78049410740 scopus 로고    scopus 로고
    • Stimulation of Sirt1-regulated FoxO protein function by the ligand-bound vitamin D receptor
    • An, B.S.; Tavera-Mendoza, L.E.; Dimitrov, V.; Wang, X.; Calderon, M.R.; Wang, H.J.; White, J.H. Stimulation of Sirt1-regulated FoxO protein function by the ligand-bound vitamin D receptor. Mol. Cell. Biol. 2010, 30, 4890-4900.
    • (2010) Mol. , vol.30 , pp. 4890-4900
    • An, B.S.1    Tavera-Mendoza, L.E.2    Dimitrov, V.3    Wang, X.4    Calderon, M.R.5    Wang, H.J.6    White, J.H.7
  • 159
    • 84926669784 scopus 로고    scopus 로고
    • Fan, T.; et al. Overexpression of SIRT1 promotes metastasis through epithelial-mesenchymal transition in hepatocellular carcinoma
    • Hao, C; Zhu, P.; Yang, X.; Han, Z.; Jiang, J.; Zong, C; Zhang, X.; Liu, W.; Zhao, Q.; Fan, T.; et al. Overexpression of SIRT1 promotes metastasis through epithelial-mesenchymal transition in hepatocellular carcinoma. BMC Cancer 2014, 14, 978.
    • (2014) BMC Cancer , vol.14 , pp. 978
    • Hao, C.1    Zhu, P.2    Yang, X.3    Han, Z.4    Jiang, J.5    Zong, C.6    Zhang, X.7    Liu, W.8    Zhao, Q.9
  • 160
    • 84923008649 scopus 로고    scopus 로고
    • Clinicopathological and prognostic role of SIRT1 in breast cancer patients: A meta-analysis
    • Cao, Y.W.; Li, Y.C.; Wan, G.X.; Du, X.M.; Li, F. Clinicopathological and prognostic role of SIRT1 in breast cancer patients: A meta-analysis. Int. J. Clin. Exp. Med. 2015, 8, 616-624.
    • (2015) Int. J. Clin. Exp. Med. , vol.8 , pp. 616-624
    • Cao, Y.W.1    Li, Y.C.2    Wan, G.X.3    Du, X.M.4    Li, F.5
  • 161
    • 84940440362 scopus 로고    scopus 로고
    • Expression/localization patterns of sirtuins (SIRT1, SIRT2, and SIRT7) during progression of cervical cancer and effects of sirtuin inhibitors on growth of cervical cancer cells
    • Singh, S.; Kumar, P.U.; Thakur, S.; Kiran, S.; Sen, B.; Sharma, S.; Rao, V.V.; Poongothai, A.R.; Ramakrishna, G. Expression/localization patterns of sirtuins (SIRT1, SIRT2, and SIRT7) during progression of cervical cancer and effects of sirtuin inhibitors on growth of cervical cancer cells. Tumour Biol. 2015, doi:10.1007/s13277-015-3300-y.
    • (2015) Tumour Biol
    • Singh, S.1    Kumar, P.U.2    Thakur, S.3    Kiran, S.4    Sen, B.5    Sharma, S.6    Rao, V.V.7    Poongothai, A.R.8    Ramakrishna, G.9
  • 162
    • 80052037691 scopus 로고    scopus 로고
    • Epigenetic regulation of caloric restriction in aging
    • Li, Y.; Daniel, M.; Tollefsbol, T.O. Epigenetic regulation of caloric restriction in aging. BMC Med. 2011, 9, 98.
    • (2011) BMC Med , vol.9 , pp. 98
    • Li, Y.1    Daniel, M.2    Tollefsbol, T.O.3
  • 163
    • 18044385966 scopus 로고    scopus 로고
    • Epigenetic regulation of vitamin D hydroxylase expression and activity in normal and malignant human prostate cells
    • Khorchide, M.; Lechner, D.; Cross, H.S. Epigenetic regulation of vitamin D hydroxylase expression and activity in normal and malignant human prostate cells. J. Steroid Biochem. Mol. Biol. 2005, 93, 167-172.
    • (2005) J. Steroid Biochem. Mol. Biol , vol.93 , pp. 167-172
    • Khorchide, M.1    Lechner, D.2    Cross, H.S.3
  • 165
    • 0035342721 scopus 로고    scopus 로고
    • 25-Hydroxyvitamin D3-1α-hydroxylase and vitamin D receptor gene expression in human colonic mucosa is elevated during early cancerogenesis
    • Cross, H.S.; Bareis, P.; Hofer, H.; Bischof, M.G.; Bajna, E.; Kriwanek, S.; Bonner, E.; Peterlik, M. 25-Hydroxyvitamin D3-1α-hydroxylase and vitamin D receptor gene expression in human colonic mucosa is elevated during early cancerogenesis. Steroids 2001, 66, 287-292.
    • (2001) Steroids , vol.66 , pp. 287-292
    • Cross, H.S.1    Bareis, P.2    Hofer, H.3    Bischof, M.G.4    Bajna, E.5    Kriwanek, S.6    Bonner, E.7    Peterlik, M.8
  • 166
    • 0033324493 scopus 로고    scopus 로고
    • Liarozole acts synergistically with 1α,25-dihydroxyvitamin D3 to inhibit growth of DU 145 human prostate cancer cells by blocking 24-hydroxylase activity
    • Ly, L.H.; Zhao, X.Y.; Holloway, L.; Feldman, D. Liarozole acts synergistically with 1α,25-dihydroxyvitamin D3 to inhibit growth of DU 145 human prostate cancer cells by blocking 24-hydroxylase activity. Endocrinology 1999, 140, 2071-2076.
    • (1999) Endocrinology , vol.140 , pp. 2071-2076
    • Ly, L.H.1    Zhao, X.Y.2    Holloway, L.3    Feldman, D.4
  • 167
    • 84881153075 scopus 로고    scopus 로고
    • Epigenetic regulation of the 1,25-dihydroxyvitamin D3 24-hydroxylase (CYP24A1) in colon cancer cells
    • Hobaus, J.; Fetahu, I.; Khorchide, M.; Manhardt, T.; Kallay, E. Epigenetic regulation of the 1,25-dihydroxyvitamin D3 24-hydroxylase (CYP24A1) in colon cancer cells. J. Steroid Biochem. Mol. Biol. 2013, 136, 296-299.
    • (2013) J. Steroid Biochem. Mol. Biol , vol.136 , pp. 296-299
    • Hobaus, J.1    Fetahu, I.2    Khorchide, M.3    Manhardt, T.4    Kallay, E.5
  • 170
    • 84888633713 scopus 로고    scopus 로고
    • Inflammation-induced cancer: Crosstalk between tumours, immune cells and microorganisms. Nat
    • Elinav, E.; Nowarski, R.; Thaiss, C.A.; Hu, B.; Jin, C.; Flavell, R.A. Inflammation-induced cancer: Crosstalk between tumours, immune cells and microorganisms. Nat. Rev. Cancer 2013, 13, 759–771.
    • (2013) Rev. Cancer , vol.13 , pp. 759-771
    • Elinav, E.1    Nowarski, R.2    Thaiss, C.A.3    Hu, B.4    Jin, C.5    Flavell, R.A.6
  • 171
    • 33645508531 scopus 로고    scopus 로고
    • Chronic inflammation: A common and important factor in the pathogenesis of neoplasia
    • Schottenfeld, D.; Beebe-Dimmer, J. Chronic inflammation: A common and important factor in the pathogenesis of neoplasia. CA Cancer J. Clin. 2006, 56, 69–83.
    • (2006) CA Cancer J. Clin , vol.56 , pp. 69-83
    • Schottenfeld, D.1    Beebe-Dimmer, J.2
  • 173
    • 84857141296 scopus 로고    scopus 로고
    • Cancer-related inflammation: Common themes and therapeutic opportunities
    • Balkwill, F.R.; Mantovani, A. Cancer-related inflammation: Common themes and therapeutic opportunities. Semin. Cancer Biol. 2011, 22, 33–40.
    • (2011) Semin. Cancer Biol , vol.22 , pp. 33-40
    • Balkwill, F.R.1    Mantovani, A.2
  • 175
    • 79955564023 scopus 로고    scopus 로고
    • Intestinal inflammation and cancer
    • Ullman, T.A.; Itzkowitz, S.H. Intestinal inflammation and cancer. Gastroenterology 2011, 140, 1807–1816.
    • (2011) Gastroenterology , vol.140 , pp. 1807-1816
    • Ullman, T.A.1    Itzkowitz, S.H.2
  • 176
    • 42649124339 scopus 로고    scopus 로고
    • TNF: A master switch for inflammation to cancer
    • Sethi, G.; Sung, B.; Aggarwal, B.B. TNF: A master switch for inflammation to cancer. Front. Biosci. 2008, 13, 5094–5107.
    • (2008) Front. Biosci , vol.13 , pp. 5094-5107
    • Sethi, G.1    Sung, B.2    Aggarwal, B.B.3
  • 177
    • 24644480749 scopus 로고    scopus 로고
    • Molecular requirements for epithelial-mesenchymal transition during tumor progression
    • Huber, M.A.; Kraut, N.; Beug, H. Molecular requirements for epithelial-mesenchymal transition during tumor progression. Curr. Opin. Cell Biol. 2005, 17, 548–558.
    • (2005) Curr. Opin. Cell Biol , vol.17 , pp. 548-558
    • Huber, M.A.1    Kraut, N.2    Beug, H.3
  • 178
    • 35148832569 scopus 로고    scopus 로고
    • Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression
    • Lo, H.W.; Hsu, S.C.; Xia, W.; Cao, X.; Shih, J.Y.; Wei, Y.; Abbruzzese, J.L.; Hortobagyi, G.N.; Hung, M.C. Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression. Cancer Res. 2007, 67, 9066–9076.
    • (2007) Cancer Res , vol.67 , pp. 9066-9076
    • Lo, H.W.1    Hsu, S.C.2    Xia, W.3    Cao, X.4    Shih, J.Y.5    Wei, Y.6    Abbruzzese, J.L.7    Hortobagyi, G.N.8    Hung, M.C.9
  • 180
    • 65349092794 scopus 로고    scopus 로고
    • Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion
    • Wu, Y.; Deng, J.; Rychahou, P.G.; Qiu, S.; Evers, B.M.; Zhou, B.P. Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion. Cancer Cell 2009, 15, 416–428.
    • (2009) Cancer Cell , vol.15 , pp. 416-428
    • Wu, Y.1    Deng, J.2    Rychahou, P.G.3    Qiu, S.4    Evers, B.M.5    Zhou, B.P.6
  • 181
    • 74549167737 scopus 로고    scopus 로고
    • Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression
    • Park, E.J.; Lee, J.H.; Yu, G.Y.; He, G.; Ali, S.R.; Holzer, R.G.; Osterreicher, C.H.; Takahashi, H.; Karin, M. Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression. Cell 2010, 140, 197–208.
    • (2010) Cell , vol.140 , pp. 197-208
    • Park, E.J.1    Lee, J.H.2    Yu, G.Y.3    He, G.4    Ali, S.R.5    Holzer, R.G.6    Osterreicher, C.H.7    Takahashi, H.8    Karin, M.9
  • 184
    • 70350500225 scopus 로고    scopus 로고
    • STATs in cancer inflammation and immunity: A leading role for STAT3
    • Yu, H.; Pardoll, D.; Jove, R. STATs in cancer inflammation and immunity: A leading role for STAT3. Nat. Rev. Cancer 2009, 9, 798–809.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 798-809
    • Yu, H.1    Pardoll, D.2    Jove, R.3
  • 185
    • 0035799531 scopus 로고    scopus 로고
    • Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells
    • Garcia, R.; Bowman, T.L.; Niu, G.; Yu, H.; Minton, S.; Muro-Cacho, C.A.; Cox, C.E.; Falcone, R.; Fairclough, R.; Parsons, S. et al. Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells. Oncogene 2001, 20, 2499–2513.
    • (2001) Oncogene , vol.20 , pp. 2499-2513
    • Garcia, R.1    Bowman, T.L.2    Niu, G.3    Yu, H.4    Minton, S.5    Muro-Cacho, C.A.6    Cox, C.E.7    Falcone, R.8    Fairclough, R.9    Parsons, S.10
  • 186
    • 84872227268 scopus 로고    scopus 로고
    • Targeting CD44-STAT3 signaling by Gemini vitamin D analog leads to inhibition of invasion in basal-like breast cancer
    • So, J.Y.; Smolarek, A.K.; Salerno, D.M.; Maehr, H.; Uskokovic, M.; Liu, F.; Suh, N. Targeting CD44-STAT3 signaling by Gemini vitamin D analog leads to inhibition of invasion in basal-like breast cancer. PLoS ONE 2013, 8, e54020.
    • (2013) Plos ONE , vol.8
    • So, J.Y.1    Smolarek, A.K.2    Salerno, D.M.3    Maehr, H.4    Uskokovic, M.5    Liu, F.6    Suh, N.7
  • 187
    • 84866406480 scopus 로고    scopus 로고
    • Suppressive effect of 19-nor-1α-25-dihydroxyvitamin D2 on gastric cancer cells and peritoneal metastasis model
    • Park, M.R.; Lee, J.H.; Park, M.S.; Hwang, J.E.; Shim, H.J.; Cho, S.H.; Chung, I.J.; Bae, W.K. Suppressive effect of 19-nor-1α-25-dihydroxyvitamin D2 on gastric cancer cells and peritoneal metastasis model. J. Korean Med. Sci. 2012, 27, 1037-1043.
    • (2012) J. Korean Med. Sci. , vol.27 , pp. 1037-1043
    • Park, M.R.1    Lee, J.H.2    Park, M.S.3    Hwang, J.E.4    Shim, H.J.5    Cho, S.H.6    Chung, I.J.7    Bae, W.K.8
  • 189
    • 0028972468 scopus 로고
    • Down-regulation of NF-kappa B protein levels in activated human lymphocytes by 1,25-dihydroxyvitamin D3
    • Yu, X.P.; Bellido, T.; Manolagas, S.C. Down-regulation of NF-kappa B protein levels in activated human lymphocytes by 1,25-dihydroxyvitamin D3. Proc. Natl. Acad. Sci. USA 1995, 92, 10990-10994.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 10990-10994
    • Yu, X.P.1    Bellido, T.2    Manolagas, S.C.3
  • 190
    • 77449083534 scopus 로고    scopus 로고
    • Molecular pathways mediating the anti-inflammatory effects of calcitriol: Implications for prostate cancer chemoprevention and treatment
    • Krishnan, A.V.; Feldman, D. Molecular pathways mediating the anti-inflammatory effects of calcitriol: Implications for prostate cancer chemoprevention and treatment. Endocr. Relat. Cancer 2010, 17, R19-R38.
    • (2010) Endocr. Relat. Cancer , vol.17 , pp. R19-R38
    • Krishnan, A.V.1    Feldman, D.2
  • 192
    • 84880050173 scopus 로고    scopus 로고
    • Receptor inhibits nuclear factor kappaB activation by interacting with IkappaB kinase beta protein
    • Chen, Y.; Zhang, J.; Ge, X.; Du, J.; Deb, D.K.; Li, Y.C. Vitamin D receptor inhibits nuclear factor kappaB activation by interacting with IkappaB kinase beta protein. J. Biol. Chem. 2013, 288, 19450-19458.
    • (2013) J. Biol. Chem , vol.288 , pp. 19450-19458
    • Chen, Y.1    Zhang, J.2    Ge, X.3    Du, J.4    Deb, D.K.5    Li, Y.C.6    Vitamin, D.7
  • 193
    • 8644271518 scopus 로고    scopus 로고
    • 1α,25(OH)2D3 regulates NF-kappaB DNA binding activity in cultured normal human keratinocytesthrough an increase in IkappaBα expression
    • Riis, J.L.; Johansen, C; Gesser, B.; Moller, K.; Larsen, C.G.; Kragballe, K.; Iversen, L. 1α,25(OH)2D3 regulates NF-kappaB DNA binding activity in cultured normal human keratinocytes through an increase in IkappaBα expression. Arch. Dermatol. Res. 2004, 296, 195-202.
    • (2004) Arch. Dermatol. Res , vol.296 , pp. 195-202
    • Riis, J.L.1    Johansen, C.2    Gesser, B.3    Moller, K.4    Larsen, C.G.5    Kragballe, K.6    Iversen, L.7
  • 194
    • 0036546501 scopus 로고    scopus 로고
    • NF-kappaB in cancer: From innocent bystander to major culprit
    • Karin, M.; Cao, Y.; Greten, F.R.; Li, Z.W. NF-kappaB in cancer: From innocent bystander to major culprit. Nat. Rev. Cancer 2002, 2, 301-310.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.W.4
  • 195
    • 84858718448 scopus 로고    scopus 로고
    • NF-kappaB and the link between inflammation and cancer
    • DiDonato, J.A.; Mercurio, F.; Karin, M. NF-kappaB and the link between inflammation and cancer. Immunol. Rev. 2012, 246, 379-400.
    • (2012) Immunol. Rev , vol.246 , pp. 379-400
    • Didonato, J.A.1    Mercurio, F.2    Karin, M.3
  • 197
    • 24744452645 scopus 로고    scopus 로고
    • Regulation of prostaglandin metabolism by calcitriol attenuates growth stimulation in prostate cancer cells
    • Moreno, J.; Krishnan, A.V.; Swami, S.; Nonn, L.; Peehl, D.M.; Feldman, D. Regulation of prostaglandin metabolism by calcitriol attenuates growth stimulation in prostate cancer cells. Cancer Res. 2005, 65, 7917-7925.
    • (2005) Cancer Res , vol.65 , pp. 7917-7925
    • Moreno, J.1    Krishnan, A.V.2    Swami, S.3    Nonn, L.4    Peehl, D.M.5    Feldman, D.6
  • 199
    • 84869868956 scopus 로고    scopus 로고
    • Calcitriol downregulates TNF-α and IL-6 expression in cultured placental cells from preeclamptic women
    • Noyola-Martinez, N.; Diaz, L.; Avila, E.; Halhali, A.; Larrea, F.; Barrera, D. Calcitriol downregulates TNF-α and IL-6 expression in cultured placental cells from preeclamptic women. Cytokine 2013, 61, 245-250.
    • (2013) Cytokine , vol.61 , pp. 245-250
    • Noyola-Martinez, N.1    Diaz, L.2    Avila, E.3    Halhali, A.4    Larrea, F.5    Barrera, D.6
  • 200
  • 201
    • 84867987339 scopus 로고    scopus 로고
    • Effects of a 1-year supplementation with cholecalciferol on interleukin-6, tumor necrosis factor-α and insulin resistance in overweight and obese subjects
    • Beilfuss, J.; Berg, V.; Sneve, M.; Jorde, R.; Kamycheva, E. Effects of a 1-year supplementation with cholecalciferol on interleukin-6, tumor necrosis factor-α and insulin resistance in overweight and obese subjects. Cytokine 2012, 60, 870-874.
    • (2012) Cytokine , vol.60 , pp. 870-874
    • Beilfuss, J.1    Berg, V.2    Sneve, M.3    Jorde, R.4    Kamycheva, E.5
  • 202
    • 84866163945 scopus 로고    scopus 로고
    • 1α,25-Dihydroxyvitamin D3 modulates the interaction between immune and colon cancer cells
    • Bessler, H.; Djaldetti, M. 1α,25-Dihydroxyvitamin D3 modulates the interaction between immune and colon cancer cells. Biomed. Pharmacother. 2012, 66, 428-432.
    • (2012) Biomed. Pharmacother , vol.66 , pp. 428-432
    • Bessler, H.1    Djaldetti, M.2
  • 203
    • 33846682591 scopus 로고    scopus 로고
    • The inflammatory cytokine tumor necrosis factor-α generates an autocrine tumor-promoting network in epithelial ovarian cancer cells
    • Kulbe, H.; Thompson, R.; Wilson, J.L.; Robinson, S.; Hagemann, T.; Fatah, R.; Gould, D.; Ayhan, A.; Balkwill, F. The inflammatory cytokine tumor necrosis factor-α generates an autocrine tumor-promoting network in epithelial ovarian cancer cells. Cancer Res. 2007, 67, 585-592.
    • (2007) Cancer Res , vol.67 , pp. 585-592
    • Kulbe, H.1    Thompson, R.2    Wilson, J.L.3    Robinson, S.4    Hagemann, T.5    Fatah, R.6    Gould, D.7    Ayhan, A.8    Balkwill, F.9
  • 204
    • 3743126193 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 is an autocrine mediator of U937 cell growth arrest and differentiation induced by vitamin D3 and retinoids
    • Defacque, H.; Piquemal, D.; Basset, A.; Marti, J.; Commes, T. Transforming growth factor-beta1 is an autocrine mediator of U937 cell growth arrest and differentiation induced by vitamin D3 and retinoids. J. Cell. Physiol. 1999, 178, 109-119.
    • (1999) J. Cell. Physiol , vol.178 , pp. 109-119
    • Defacque, H.1    Piquemal, D.2    Basset, A.3    Marti, J.4    Commes, T.5
  • 205
    • 33746553766 scopus 로고    scopus 로고
    • Prostate derived factor in human prostate cancer cells: Gene induction by vitamin D via a p53-dependent mechanism and inhibition of prostate cancer cell growth
    • Lambert, J.R.; Kelly, J.A.; Shim, M.; Huffer, W.E.; Nordeen, S.K.; Baek, S.J.; Eling, T.E.; Lucia, M.S. Prostate derived factor in human prostate cancer cells: Gene induction by vitamin D via a p53-dependent mechanism and inhibition of prostate cancer cell growth. J. Cell. Physiol. 2006, 208, 566-574.
    • (2006) J. Cell. Physiol , vol.208 , pp. 566-574
    • Lambert, J.R.1    Kelly, J.A.2    Shim, M.3    Huffer, W.E.4    Nordeen, S.K.5    Baek, S.J.6    Eling, T.E.7    Lucia, M.S.8
  • 208
    • 0034689445 scopus 로고    scopus 로고
    • Immunosuppression mediated by tumor cells: A challenge for immunotherapeutic approaches
    • Paillard, F. Immunosuppression mediated by tumor cells: A challenge for immunotherapeutic approaches. Hum. Gene Ther. 2000, 11, 657-658.
    • (2000) Hum. Gene Ther , vol.11 , pp. 657-658
    • Paillard, F.1
  • 209
    • 0032709778 scopus 로고    scopus 로고
    • T cell-derived IL-10 promotes lung cancer growth by suppressing both T cell and APC function
    • Sharma, S.; Stolina, M.; Lin, Y.; Gardner, B.; Miller, P.W.; Kronenberg, M.; Dubinett, S.M. T cell-derived IL-10 promotes lung cancer growth by suppressing both T cell and APC function. J. Immunol. 1999, 163, 5020-5028.
    • (1999) J. Immunol , vol.163 , pp. 5020-5028
    • Sharma, S.1    Stolina, M.2    Lin, Y.3    Gardner, B.4    Miller, P.W.5    Kronenberg, M.6    Dubinett, S.M.7


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