-
1
-
-
2342464085
-
The two NF-κB activation pathways and their role in innate and adaptive immunity
-
Bonizzi, G., and Karin, M. (2004) The two NF-κB activation pathways and their role in innate and adaptive immunity. Trends Immunol. 25, 280-288
-
(2004)
Trends Immunol
, vol.25
, pp. 280-288
-
-
Bonizzi, G.1
Karin, M.2
-
2
-
-
16844366650
-
Nuclear factor-αB inhibitors as sensitizers to anticancer drugs
-
Nakanishi, C., and Toi, M. (2005) Nuclear factor-αB inhibitors as sensitizers to anticancer drugs. Nat. Rev. Cancer 5, 297-309
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 297-309
-
-
Nakanishi, C.1
Toi, M.2
-
3
-
-
80051987703
-
Crosstalk in NF-κB signaling pathways
-
Oeckinghaus, A., Hayden, M. S., and Ghosh, S. (2011) Crosstalk in NF-κB signaling pathways. Nat. Immunol. 12, 695-708
-
(2011)
Nat. Immunol
, vol.12
, pp. 695-708
-
-
Oeckinghaus, A.1
Hayden, M.S.2
Ghosh, S.3
-
4
-
-
0032589462
-
IκB kinases phosphorylate NF-κB p65 subunit on serine 536 in the transactivation domain
-
Sakurai, H., Chiba, H., Miyoshi, H., Sugita, T., and Toriumi, W. (1999) IκB kinases phosphorylate NF-κB p65 subunit on serine 536 in the transactivation domain. J. Biol. Chem. 274, 30353-30356
-
(1999)
J. Biol. Chem
, vol.274
, pp. 30353-30356
-
-
Sakurai, H.1
Chiba, H.2
Miyoshi, H.3
Sugita, T.4
Toriumi, W.5
-
5
-
-
53849136271
-
Vitamin D and human health. Lessons from vitamin D receptor null mice
-
Bouillon, R., Carmeliet, G., Verlinden, L., van Etten, E., Verstuyf, A., Luderer, H. F., Lieben, L., Mathieu, C., and Demay, M. (2008) Vitamin D and human health. Lessons from vitamin D receptor null mice. Endocr. Rev. 29, 726-776
-
(2008)
Endocr. Rev
, vol.29
, pp. 726-776
-
-
Bouillon, R.1
Carmeliet, G.2
Verlinden, L.3
Van Etten, E.4
Verstuyf, A.5
Luderer, H.F.6
Lieben, L.7
Mathieu, C.8
Demay, M.9
-
6
-
-
0031892913
-
The nuclear vitamin D receptor. Biological and molecular regulatory properties revealed
-
Haussler, M. R., Whitfield, G. K., Haussler, C. A., Hsieh, J. C., Thompson, P. D., Selznick, S. H., Dominguez, C. E., and Jurutka, P. W. (1998) The nuclear vitamin D receptor. Biological and molecular regulatory properties revealed. J. Bone Miner. Res. 13, 325-349
-
(1998)
J. Bone Miner. Res
, vol.13
, pp. 325-349
-
-
Haussler, M.R.1
Whitfield, G.K.2
Haussler, C.A.3
Hsieh, J.C.4
Thompson, P.D.5
Selznick, S.H.6
Dominguez, C.E.7
Jurutka, P.W.8
-
7
-
-
0038636398
-
Vitamin D. More than a "bonea-fide" hormone
-
Sutton, A. L., and MacDonald, P. N. (2003) Vitamin D. More than a "bonea-fide" hormone. Mol. Endocrinol. 17, 777-791
-
(2003)
Mol. Endocrinol
, vol.17
, pp. 777-791
-
-
Sutton, A.L.1
MacDonald, P.N.2
-
8
-
-
18344389705
-
Vitamin D 3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of β-catenin signaling
-
Pálmer, H. G., González-Sancho, J. M., Espada, J., Berciano, M. T., Puig, I., Baulida, J., Quintanilla, M., Cano, A., de Herreros, A. G., Lafarga, M., and Muñoz, A. (2001) Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of β-catenin signaling. J. Cell Biol. 154, 369-387
-
(2001)
J. Cell Biol
, vol.154
, pp. 369-387
-
-
Pálmer, H.G.1
González-Sancho, J.M.2
Espada, J.3
Berciano, M.T.4
Puig, I.5
Baulida, J.6
Quintanilla, M.7
Cano, A.8
De Herreros, A.G.9
Lafarga, M.10
Muñoz, A.11
-
9
-
-
35648976022
-
1,25-Dihydroxyvitamin D3 suppresses renin gene transcription by blocking the activity of the cyclic AMP response element in the renin gene promoter
-
Yuan, W., Pan, W., Kong, J., Zheng, W., Szeto, F. L., Wong, K. E., Cohen, R., Klopot, A., Zhang, Z., and Li, Y. C. (2007) 1,25-Dihydroxyvitamin D3 suppresses renin gene transcription by blocking the activity of the cyclic AMP response element in the renin gene promoter. J. Biol. Chem. 282, 29821-29830
-
(2007)
J. Biol. Chem
, vol.282
, pp. 29821-29830
-
-
Yuan, W.1
Pan, W.2
Kong, J.3
Zheng, W.4
Szeto, F.L.5
Wong, K.E.6
Cohen, R.7
Klopot, A.8
Zhang, Z.9
Li, Y.C.10
-
10
-
-
33745839652
-
Increased NF-κB activity in fibroblasts lacking the vitamin D receptor
-
Sun, J., Kong, J., Duan, Y., Szeto, F. L., Liao, A., Madara, J. L., and Li, Y. C. (2006) Increased NF-κB activity in fibroblasts lacking the vitamin D receptor. Am. J. Physiol. Endocrinol. Metab. 291, E315-322
-
(2006)
Am. J. Physiol. Endocrinol. Metab
, vol.291
-
-
Sun, J.1
Kong, J.2
Duan, Y.3
Szeto, F.L.4
Liao, A.5
Madara, J.L.6
Li, Y.C.7
-
11
-
-
0031974910
-
Inhibition of IL-12 production by 1,25-dihydroxyvitamin D3. Involvement of NF-κB downregulation in transcriptional repression of the p40 gene
-
D'Ambrosio, D., Cippitelli, M., Cocciolo, M. G., Mazzeo, D., Di Lucia, P., Lang, R., Sinigaglia, F., and Panina-Bordignon, P. (1998) Inhibition of IL-12 production by 1,25-dihydroxyvitamin D3. Involvement of NF-κB downregulation in transcriptional repression of the p40 gene. J. Clin. Invest. 101, 252-262
-
(1998)
J. Clin. Invest
, vol.101
, pp. 252-262
-
-
D'Ambrosio, D.1
Cippitelli, M.2
Cocciolo, M.G.3
Mazzeo, D.4
Di Lucia, P.5
Lang, R.6
Sinigaglia, F.7
Panina-Bordignon, P.8
-
12
-
-
8644271518
-
1,25(OH) 2) D(3) regulates NF-κB DNA binding activity in cultured normal human keratinocytes through an increase in IκBα expression
-
Riis, J. L., Johansen, C., Gesser, B., Møller, K., Larsen, C. G., Kragballe, K., and Iversen, L. (2004) 1,25(OH)(2)D(3) regulates NF-κB DNA binding activity in cultured normal human keratinocytes through an increase in IκBα expression. Arch. Dermatol. Res. 296, 195-202
-
(2004)
Arch. Dermatol. Res
, vol.296
, pp. 195-202
-
-
Riis, J.L.1
Johansen, C.2
Gesser, B.3
Møller, K.4
Larsen, C.G.5
Kragballe, K.6
Iversen, L.7
-
13
-
-
66049093473
-
1,25-Dihydroxyvitamin D3 suppresses high glucoseinduced angiotensinogen expression in kidney cells by blocking the NF-κB pathway
-
Deb, D. K., Chen, Y., Zhang, Z., Zhang, Y., Szeto, F. L., Wong, K. E., Kong, J., and Li, Y. C. (2009) 1,25-Dihydroxyvitamin D3 suppresses high glucoseinduced angiotensinogen expression in kidney cells by blocking the NF-κB pathway. Am. J. Physiol. Renal Physiol. 296, F1212-1218
-
(2009)
Am. J. Physiol. Renal Physiol
, vol.296
-
-
Deb, D.K.1
Chen, Y.2
Zhang, Z.3
Zhang, Y.4
Szeto, F.L.5
Wong, K.E.6
Kong, J.7
Li, Y.C.8
-
14
-
-
34447530298
-
1,25-Dihydroxyvitamin D(3) targeting of NF-κB suppresses high glucose-induced MCP-1 expression in mesangial cells
-
Zhang, Z., Yuan, W., Sun, L., Szeto, F. L., Wong, K. E., Li, X., Kong, J., and Li, Y. C. (2007) 1,25-Dihydroxyvitamin D(3) targeting of NF-κB suppresses high glucose-induced MCP-1 expression in mesangial cells. Kidney Int. 72, 193-201
-
(2007)
Kidney Int
, vol.72
, pp. 193-201
-
-
Zhang, Z.1
Yuan, W.2
Sun, L.3
Szeto, F.L.4
Wong, K.E.5
Li, X.6
Kong, J.7
Li, Y.C.8
-
15
-
-
79951946021
-
1,25-Dihydroxyvitamin D(3) suppresses inflammation-induced expression of plasminogen activator inhibitor-1 by blocking nuclear factor-αB activation
-
Chen, Y., Kong, J., Sun, T., Li, G., Szeto, F. L., Liu, W., Deb, D. K., Wang, Y., Zhao, Q., Thadhani, R., and Li, Y. C. (2011) 1,25-Dihydroxyvitamin D(3) suppresses inflammation-induced expression of plasminogen activator inhibitor-1 by blocking nuclear factor-αB activation. Arch. Biochem. Biophys. 507, 241-247
-
(2011)
Arch. Biochem. Biophys
, vol.507
, pp. 241-247
-
-
Chen, Y.1
Kong, J.2
Sun, T.3
Li, G.4
Szeto, F.L.5
Liu, W.6
Deb, D.K.7
Wang, Y.8
Zhao, Q.9
Thadhani, R.10
Li, Y.C.11
-
16
-
-
84875437416
-
1,25-Dihydroxyvitamin D promotes negative feedback regulation of TLR signaling via targeting microRNA- 155-SOCS1 in macrophages
-
Chen, Y., Liu, W., Sun, T., Huang, Y., Wang, Y., Deb, D. K., Yoon, D., Kong, J., Thadhani, R., and Li, Y. C. (2013) 1,25-Dihydroxyvitamin D promotes negative feedback regulation of TLR signaling via targeting microRNA- 155-SOCS1 in macrophages. J. Immunol. 190, 3687-3695
-
(2013)
J. Immunol
, vol.190
, pp. 3687-3695
-
-
Chen, Y.1
Liu, W.2
Sun, T.3
Huang, Y.4
Wang, Y.5
Deb, D.K.6
Yoon, D.7
Kong, J.8
Thadhani, R.9
Li, Y.C.10
-
17
-
-
0031595760
-
1,25-dihydroxyvitamin D3 decreases DNA binding of nuclear factor-αB in human fibroblasts
-
Harant, H., Wolff, B., and Lindley, I. J. (1998) 1,25-dihydroxyvitamin D3 decreases DNA binding of nuclear factor-αB in human fibroblasts. FEBS Lett. 436, 329-334
-
(1998)
FEBS Lett
, vol.436
, pp. 329-334
-
-
Harant, H.1
Wolff, B.2
Lindley, I.J.3
-
18
-
-
4043060025
-
A vitamin D analog down-regulates proinflammatory chemokine production by pancreatic islets inhibiting T cell recruitment and type 1 diabetes development
-
Giarratana, N., Penna, G., Amuchastegui, S., Mariani, R., Daniel, K. C., and Adorini, L. (2004) A vitamin D analog down-regulates proinflammatory chemokine production by pancreatic islets inhibiting T cell recruitment and type 1 diabetes development. J. Immunol. 173, 2280-2287
-
(2004)
J. Immunol
, vol.173
, pp. 2280-2287
-
-
Giarratana, N.1
Penna, G.2
Amuchastegui, S.3
Mariani, R.4
Daniel, K.C.5
Adorini, L.6
-
19
-
-
1542676905
-
Direct transcriptional regulation of RelB by 1,25-dihydroxyvitamin D3 and its analogs. Physiologic and therapeutic implications for dendritic cell function
-
Dong, X., Craig, T., Xing, N., Bachman, L. A., Paya, C. V., Weih, F., McKean, D. J., Kumar, R., and Griffin, M. D. (2003) Direct transcriptional regulation of RelB by 1,25-dihydroxyvitamin D3 and its analogs. Physiologic and therapeutic implications for dendritic cell function. J. Biol. Chem. 278, 49378-49385
-
(2003)
J. Biol. Chem
, vol.278
, pp. 49378-49385
-
-
Dong, X.1
Craig, T.2
Xing, N.3
Bachman, L.A.4
Paya, C.V.5
Weih, F.6
McKean, D.J.7
Kumar, R.8
Griffin, M.D.9
-
20
-
-
0028972468
-
Down-regulation of NF-κB protein levels in activated human lymphocytes by 1,25-dihydroxyvitamin D3
-
[published erratum appears in Proc Natl. Acad. Sci. U.S.A. 1996 Jan 9;93(1): 524]
-
Yu, X. P., Bellido, T., and Manolagas, S. C. (1995) Down-regulation of NF-κB protein levels in activated human lymphocytes by 1,25-dihydroxyvitamin D3 [published erratum appears in Proc. Natl. Acad. Sci. U.S.A. 1996 Jan 9;93(1): 524]. Proc. Natl. Acad. Sci. U.S.A. 92, 10990-10994
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 10990-10994
-
-
Yu, X.P.1
Bellido, T.2
Manolagas, S.C.3
-
21
-
-
15444367188
-
Integration of the NFκB p65 subunit into the vitamin D receptor transcriptional complex. Identification of p65 domains that inhibit 1,25-dihydroxyvitamin D3- stimulated transcription
-
Lu, X., Farmer, P., Rubin, J., and Nanes, M. S. (2004) Integration of the NFκB p65 subunit into the vitamin D receptor transcriptional complex. Identification of p65 domains that inhibit 1,25-dihydroxyvitamin D3- stimulated transcription. J. Cell Biochem. 92, 833-848
-
(2004)
J. Cell Biochem
, vol.92
, pp. 833-848
-
-
Lu, X.1
Farmer, P.2
Rubin, J.3
Nanes, M.S.4
-
22
-
-
0034830518
-
Effects of vitamin D receptor inactivation on the expression of calbindins and calcium metabolism
-
Li, Y. C., Bolt, M. J. G., Cao, L.-P., and Sitrin, M. D. (2001) Effects of vitamin D receptor inactivation on the expression of calbindins and calcium metabolism. Am. J. Physiol. Endocrinol. Metab. 281, E558-E564
-
(2001)
Am. J. Physiol. Endocrinol. Metab
, vol.281
-
-
Li, Y.C.1
Bolt, M.J.G.2
Cao, L.-P.3
Sitrin, M.D.4
-
23
-
-
0032575379
-
Direct phosphorylation of IκB by IKKα and IKKβ. Discrimination between free and NF-κB-bound substrate
-
Zandi, E., Chen, Y., and Karin, M. (1998) Direct phosphorylation of IκB by IKKα and IKKβ. Discrimination between free and NF-κB-bound substrate. Science 281, 1360-1363
-
(1998)
Science
, vol.281
, pp. 1360-1363
-
-
Zandi, E.1
Chen, Y.2
Karin, M.3
-
24
-
-
0030685825
-
IKK-1 and IKK-2. Cytokine-activated IκB kinases essential for NF-κB activation
-
Mercurio, F., Zhu, H., Murray, B. W., Shevchenko, A., Bennett, B. L., Li, J., Young, D. B., Barbosa, M., Mann, M., Manning, A., and Rao, A. (1997) IKK-1 and IKK-2. Cytokine-activated IκB kinases essential for NF-κB activation. Science 278, 860-866
-
(1997)
Science
, vol.278
, pp. 860-866
-
-
Mercurio, F.1
Zhu, H.2
Murray, B.W.3
Shevchenko, A.4
Bennett, B.L.5
Li, J.6
Young, D.B.7
Barbosa, M.8
Mann, M.9
Manning, A.10
Rao, A.11
-
25
-
-
20544462600
-
1,25 dihydroxyvitamin D amplifies type a natriuretic peptide receptor expression and activity in target cells
-
Chen, S., Ni, X. P., Humphreys, M. H., and Gardner, D. G. (2005) 1,25 dihydroxyvitamin D amplifies type a natriuretic peptide receptor expression and activity in target cells. J. Am. Soc. Nephrol. 16, 329-339
-
(2005)
J. Am. Soc. Nephrol
, vol.16
, pp. 329-339
-
-
Chen, S.1
Ni, X.P.2
Humphreys, M.H.3
Gardner, D.G.4
-
26
-
-
54749105918
-
Paricalcitol inhibits renal inflammation by promoting vitamin D receptor-mediated sequestration of NF-κB signaling
-
Tan, X., Wen, X., and Liu, Y. (2008) Paricalcitol inhibits renal inflammation by promoting vitamin D receptor-mediated sequestration of NF-κB signaling. J. Am. Soc. Nephrol. 19, 1741-1752
-
(2008)
J. Am. Soc. Nephrol
, vol.19
, pp. 1741-1752
-
-
Tan, X.1
Wen, X.2
Liu, Y.3
-
27
-
-
0029149894
-
Transcriptional repression of the interleukin-2 gene by vitamin D3. Direct inhibition of NFATp/AP-1 complex formation by a nuclear hormone receptor
-
Alroy, I., Towers, T. L., and Freedman, L. P. (1995) Transcriptional repression of the interleukin-2 gene by vitamin D3. Direct inhibition of NFATp/AP-1 complex formation by a nuclear hormone receptor. Mol. Cell Biol. 15, 5789-5799
-
(1995)
Mol. Cell Biol
, vol.15
, pp. 5789-5799
-
-
Alroy, I.1
Towers, T.L.2
Freedman, L.P.3
-
28
-
-
0032562621
-
Granulocyte-macrophage colony-stimulating factor gene transcription is directly repressed by the vitamin D3 receptor. Implications for allosteric influences on nuclear receptor structure and function by a DNA element
-
Towers, T. L., and Freedman, L. P. (1998) Granulocyte-macrophage colony-stimulating factor gene transcription is directly repressed by the vitamin D3 receptor. Implications for allosteric influences on nuclear receptor structure and function by a DNA element. J. Biol. Chem. 273, 10338-10348
-
(1998)
J. Biol. Chem
, vol.273
, pp. 10338-10348
-
-
Towers, T.L.1
Freedman, L.P.2
-
29
-
-
0032079521
-
A negative vitamin D response DNA element in the human parathyroid hormone-related peptide gene binds to vitamin D receptor along with Ku antigen to mediate negative gene regulation by vitamin D
-
Nishishita, T., Okazaki, T., Ishikawa, T., Igarashi, T., Hata, K., Ogata, E., and Fujita, T. (1998) A negative vitamin D response DNA element in the human parathyroid hormone-related peptide gene binds to vitamin D receptor along with Ku antigen to mediate negative gene regulation by vitamin D. J. Biol. Chem. 273, 10901-10907
-
(1998)
J. Biol. Chem
, vol.273
, pp. 10901-10907
-
-
Nishishita, T.1
Okazaki, T.2
Ishikawa, T.3
Igarashi, T.4
Hata, K.5
Ogata, E.6
Fujita, T.7
-
30
-
-
0033918407
-
VDR-Alien. A novel, DNA-selective vitamin D 3) receptor-corepressor partnership
-
Polly, P., Herdick, M., Moehren, U., Baniahmad, A., Heinzel, T., and Carlberg, C. (2000) VDR-Alien. A novel, DNA-selective vitamin D(3) receptor-corepressor partnership. FASEB J. 14, 1455-1463
-
(2000)
FASEB J.
, vol.14
, pp. 1455-1463
-
-
Polly, P.1
Herdick, M.2
Moehren, U.3
Baniahmad, A.4
Heinzel, T.5
Carlberg, C.6
-
31
-
-
44349182071
-
Vitamin D-dependent recruitment of corepressors to vitamin D/retinoid X receptor heterodimers
-
Sánchez-Martínez, R., Zambrano, A., Castillo, A. I., and Aranda, A. (2008) Vitamin D-dependent recruitment of corepressors to vitamin D/retinoid X receptor heterodimers. Mol. Cell Biol. 28, 3817-3829
-
(2008)
Mol. Cell Biol
, vol.28
, pp. 3817-3829
-
-
Sánchez-Martínez, R.1
Zambrano, A.2
Castillo, A.I.3
Aranda, A.4
-
32
-
-
2342623470
-
Transrepression by a liganded nuclear receptor via a bHLH activator through co-regulator switching
-
Murayama, A., Kim, M.-S., Yanagisawa, J., Takeyama, K., and Kato, S. (2004) Transrepression by a liganded nuclear receptor via a bHLH activator through co-regulator switching. EMBO J. 23, 1598-1608
-
(2004)
EMBO J.
, vol.23
, pp. 1598-1608
-
-
Murayama, A.1
Kim, M.-S.2
Yanagisawa, J.3
Takeyama, K.4
Kato, S.5
-
33
-
-
33644850904
-
The molecular basis of vitamin D receptor and β-catenin crossregulation
-
Shah, S., Islam, M. N., Dakshanamurthy, S., Rizvi, I., Rao, M., Herrell, R., Zinser, G., Valrance, M., Aranda, A., Moras, D., Norman, A., Welsh, J., and Byers, S. W. (2006) The molecular basis of vitamin D receptor and β-catenin crossregulation. Mol. Cell 21, 799-809
-
(2006)
Mol. Cell
, vol.21
, pp. 799-809
-
-
Shah, S.1
Islam, M.N.2
Dakshanamurthy, S.3
Rizvi, I.4
Rao, M.5
Herrell, R.6
Zinser, G.7
Valrance, M.8
Aranda, A.9
Moras, D.10
Norman, A.11
Welsh, J.12
Byers, S.W.13
|