Vitamin D3-induced apoptosis of murine squamous cell carcinoma cells: Selective induction of caspase-dependent MEK cleavage and up-regulation of MEKK-1

Journal of Biological Chemistry

Volumn 276, Issue 28, 2001, Pages 26365-26373

  McGuire, Terence F ^a,b   Trump, Donald L ^a,b   Johnson, Candace S ^a,b  

^a Department of Pharmacology ^*  (United States)

^b UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; ENZYME INHIBITION; ENZYME KINETICS; PROTEINS; TUMORS; VITAMINS;

PHOSPHORYLATIONS; PROTEOLYSIS;

BIOCHEMISTRY;

CASPASE; CISPLATIN; COLECALCIFEROL; ETOPOSIDE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PROTEIN KINASE B; MAP3K1 PROTEIN, HUMAN; MAP3K1 PROTEIN, MOUSE; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 1; PROTEIN SERINE THREONINE KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SQUAMOUS CELL CARCINOMA; WESTERN BLOTTING; ANIMAL; CELL CULTURE; DRUG EFFECT; HUMAN; METABOLISM; MOUSE; PATHOLOGY; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALIA; MURINAE;

ANIMALS; APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CASPASES; CHOLECALCIFEROL; HUMANS; MAP KINASE KINASE KINASE 1; MICE; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0035854680     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010101200     Document Type: Article

References (74)

1. Chouvet, C., Vicard, E., Devonec, M., and Saez, S. (1986) J. Steroid Biochem. 24, 373-376
2. Welsh, J. (1994) Biochem. Cell Biol. 72, 537-545
3. Fife, R., Sledge, G. J., and Proctor, C. (1997) Cancer Lett. 120, 65-69
4. Zhuang, S., and Burnstein, K. (1998) Endocrinology 139, 1197-1207
5. Diaz, G., Paraskeva, C., Thomas, M., Binderup, L., and Hague, A. (2000) Cancer Res. 60, 2304-2312
6. Danielsson, C., Fehsel, K., Polly, P., and Carlberg, C. (1998) Cell Death Differ. 5, 946-952
7. Abe, E., Miyaura, C., Sakagami, H., Takeda, M., Konno, K., Yamazaki, T., Yoshiki, S., and Suda, T. (1981) Proc. Natl. Acad. Sci. U. S. A. 78, 4990-4995
8. Liu, M., Lee, M.-H., Cohen, M., Bommakanti, M., and Freedman, L. (1996) Genes Dev. 10, 142-153
9. Jiang, H., Lin, J., Su, Z.-Z., Collart, F., Huberman, E., and Fisher, P. (1994) Oncogene 9, 3397-3406
10. Getzenberg, R., Light, B., Lapco, P., Konety, B., Nangia, A., Acierno, J., Dhir, R., Shurin, Z., Day, R., Trump, D., and Johnson, C. (1997) Urology 50, 999-1006
11. Eisman, J., Barkla, D., and Tutton, P. (1987) Cancer Res. 47, 21-25
12. Welsh, J., Van Weelden, K., Flanagan, L., Byrne, I., Nolan, E., and Narvaez, C. (1998) Subcell. Biochem. 30, 245-270
13. Evans, S., Soldatenkov, V., Shchepotin, E., Bogrash, E., and Shchepotin, I. (1999) Int. J. Oncol. 14, 979-985
14. Fioravanti, L., Miodini, P., Cappelletti, V., and DiFronzo, G. (1998) Anticancer Res. 18, 1703-1708
15. Hansen, C., and Maenpaa, P. (1997) Biochem. Pharmacol. 54, 1173-1179
16. Blutt, S., Polek, T., Stewart, L., Kattan, M., and Weigel, N. (2000) Cancer Res. 60, 779-782
17. James, S., Mercer, E., Brady, M., Binderup, L., and Colston, K. (1998) Br. J. Pharmacol. 125, 953-962
18. Verlinden, L., Verstuyf, A., Van Camp, M., Marcelis, S., Sabbe, K., Zhao, X., De Clercq, P., Vandewalle, M., and Bouillon, R. (2000) Cancer Res. 60, 2673-2679
19. McElwain, M., Dettlebach, M., Modzelewski, R., Russell, D., Uskokovic, M., Smith, D., Trump, D., and Johnson, C. (1995) Mol. Cell. Diff. 3, 31-50
20. Hershberger, P., Modzelewski, R., Shurin, Z., Rueger, R., Trump, D., and Johnson, C. (1999) Cancer Res. 59, 2644-2649
21. Blutt, S., and Weigel, N. (1999) Proc. Soc. Exp. Biol. Med. 221, 89-98
22. Campbell, M., Elstner, E., Holden, S., Uskokovic, M., and and Koeffler, H. (1997) J. Mol. Endocrinol. 19, 15-27
23. Kawa, S., Nikaido, T., Aoki, Y., Zhai, Y., Kumagai, T., Furihata, K., Fugii, S., and Kiyosowa, K. (1997) Br. J. Cancer 76, 884-889
24. Narvaez, C., and Welsh, J. (1997) Endocrinology 138, 4690-4698
25. Simboli-Campbell, M., Narvaez, C., Tenniswood, M., and Welsh, J. (1996) J. Steroid Biochem. Mol. Biol. 58, 367-376
26. Simboli-Campbell, M., Narvaez, C., van Weelden, K., Tenniswood, M., and Welsh, J. (1997) Breast Cancer Res. Treat. 42, 31-41
27. Blutt, S., McDonnell, T., Polek, T., and Weigel, N. (2000) Endocrinology 141, 10-17
28. Van Weelden, K., Flanagan, L., Binderup, L., Tenniswood, M., and Welsh, J. (1998) Endocrinology 139, 2102-2110
29. Mathiasen, I., Lademann, U., and Jaattela, M. (1999) Cancer Res. 59, 4848-4856
30. Rozen, F., and Pollak, M. (1999) Int. J. Oncol. 15, 589-594
31. Xie, S., Pirianov, G., and Colston, K. (1999) Eur. J. Cancer 35, 1717-1723
32. Yu, H., and Berkel, H. (1999) J. LA State Med. Soc. 151, 218-223
33. Jarpe, M., Widmann, C., Knall, C., Schlesinger, T., Gibson, S., Yujiri, T., Fanger, G., Gelfand, E., and Johnson, G. (1998) Oncogene 17, 1475-1482
34. Dent, P., Jarvis, W., Birrer, M., Fisher, P., Schmidt-Ullrich, R., and Grant, S. (1998) Leukemia 12, 1843-1850
35. Sanchez-Perez, I., and Perona, R. (1999) FEBS Lett. 453, 151-158
36. Chen, Y.-R., Wang, X., Templeton, D., Davis, R., and Tan, T.-H. (1996) J. Biol. Chem. 271, 31929-31936
37. Verheij, M., Bose, R., Lin, X., Yao, B., Jarvis, W., Grant, S., Birrer, M., Szabo, E., Zon, L., Kyriakis, J., Haimovitz-Friedman, A., Fuks, Z., and Nolesnick, R. (1996) Nature 380, 75-79
38. Toyoshima, F., Moriguchi, T., and Nishida, E. (1997) J. Cell Biol. 139, 1005-1015
39. Le Gall, M., Chambard, J., Breittmayer, J., Grall, D., Pouyssegur, J., and Van Obberghen-Scilling, E. (2000) Mol. Cell. Biol. 20, 1103-1112
40. Erhardt, P., Schremser, E., and Cooper, G. (1999) Mol. Cell. Biol. 19, 5308-5315
41. Xia, Z., Dickens, M., Raingeaud, J., Davis, R., and Greenberg, M. (1995) Science 270, 1326-1331
42. Gardner, A., and Johnson, G. (1996) J. Biol. Chem. 271, 14560-14566
43. Chen, R., Su, Y., Chuang, R., and Chang, T. (1998) Oncogene 17, 1959-1968
44. Datta, S., Dudek, H., Tao, X., Masters, S., Fu, H., Gotoh, Y., and Greenberg, M. (1997) Cell 91, 231-241
45. del Peso, L., Gonzalez-Garcia, M., Page, C., Herrera, R., and Nunez, G. (1997) Science 278, 687-689
46. Cardone, M., Salvesen, G., Widmann, C., Johnson, G., and Frisch, S. (1997) Cell 90, 315-323
47. Rudel, T., and Bokoch, G. (1997) Science 276, 1571-1574
48. Xu, S., Robbins, D., Christerson, L., English, J., Vanderbilt, C., and Cobb, M. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 5291-5295
49. Widmann, C., Gerwins, P., Johnson, N., Jarpe, M. B., and Johnson, G. L. (1998) Mol. Cell. Biol. 18, 2416-2429
50. Deak, J., Cross, J., Lewis, M., Qian, Y., Parrott, L., Distelhorst, C., and Templeton, D. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 5595-5600
51. Light, B., Yu, W.-D., McElwain, M., Russell, D., Trump, D., and Johnson, C. (1997) Cancer Res. 57, 3759-3764
52. Widmann, C., Gibson, S., and Johnson, G. L. (1998) J. Biol. Chem. 273, 7141-7147
53. Wood, D., and Newcomb, E. (1999) J. Biol. Chem. 274, 8309-8315
54. Wood, D., Thomas, A., Devi, L., Berman, Y., Beavis, R., Reed, J., and Newcomb, E. (1998) Oncogene 17, 1069-1078
55. Khwaja, A., and Downward, J. (1997) J. Cell Biol. 139, 1017-1023
56. Liu, Z.-G., Hsu, H., Goeddel, D., and Karin, M. (1996) Cell 87, 565-576
57. Nishina, H., Fischer, K., Radvanyi, L., Shahinian, A., Hakem, R., Rubie, E., Bernstein, A., Mak, T., Woodgett, J., and Penninger, J. (1997) Nature 385, 350-353
58. Smith, A., Ramos-Morales, F., Ashworth, A., and Collins, M. (1997) Curr. Biol. 7, 893-896
59. Widmann, C., Gibson, S., Jarpe, M. B., and Johnson, G. L. (1999) Physiol. Rev. 79, 143-180
60. Deak, J., and Templeton, D. (1997) Biochem. J. 322, 185-192
61. Siow, Y., Kalmar, G., Sanghera, J., Tai, T., Oh, S., and Pelech, S. (1997) J. Biol. Chem. 272, 7586-7594
62. Fanger, G., Widmann, C., Porter, A., Sather, S., Johnson, G., and Vaillancourt, R. (1998) J. Biol. Chem. 273, 3476-3483
63. Gross, C., Stamey, T., Hancock, S., and Feldman, D. (1998) J. Urol. 159, 2035-2040
64. Trump, D., Serafine, S., Brufsky, A., Muindi, J., Bernardi, R., Potter, D., and Johnson, C. (2000) Proc. Am. Soc. Clin. Oncol. 19, 337a
65. Johnson, C., Egorin, M., Zuhowski, E., Parise, R., Cappozolli, M., Belani, C., Long, G., Muindi, J., and Trump, D. (2000) Proc. Am. Soc. Clin. Oncol. 19, 210a
66. Pirianov, G., Danielsson, C., Carlberg, C., James, S., and Colston, K. (1999) Cell Death Differ. 6, 890-901
67. Sundaram, S., and Gewirtz, D. (1999) Radiat. Res. 152, 479-486
68. Cho, Y., Christensen, C., Saunders, D., Lawrence, W., Deppe, G., Malviya, V., and Malone, J. (1991) Cancer Res. 51, 2848-2853
69. Opolski, A., Wietrzyk, J., Siwinska, A., Marcinkowska, E., Chrobak, A., Radzikowski, C., and Kutner, A. (2000) Curr. Pharm. Des. 6, 755-765
70. Wang, Q., Yang, W., Uytingco, M., Christakos, S., and Wieder, R. (2000) Cancer Res. 60, 2040-2048
71. Widmann, C., Johnson, N., Gardner, A., Smith, R., and Johnson, G. L. (1997) Oncogene 15, 2439-2447
72. Blanc, C., Deveraux, Q., Krajewski, S., Janicke, R., Porter, A., Reed, J., Jaggi, R., and Marti, A. (2000) Cancer Res. 60, 4386-4390
73. Gebauer, G., Mirakhur, B., Nguyen, Q., Shore, S., Simpkins, H., and Dhanasekaran, N. (2000) Int. J. Oncol. 16, 321-325
74. Page, C., Lin, H., Jin, Y., Castle, V., Nunez, G., Huang, M., and Lin, J. (2000) Anticancer Res. 20, 407-416