메뉴 건너뛰기




Volumn 14, Issue 1, 2014, Pages

Calcitriol restores antiestrogen responsiveness in estrogen receptor negative breast cancer cells: A potential new therapeutic approach

Author keywords

Breast cancer; Calcitriol; Estrogen receptor; Hormonal therapy; VDR

Indexed keywords

CALCITRIOL; CYCLIN D1; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; FULVESTRANT; PROLACTIN; VITAMIN D RECEPTOR;

EID: 84897436484     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-14-230     Document Type: Article
Times cited : (46)

References (48)
  • 1
    • 13644259990 scopus 로고    scopus 로고
    • Molecular evolution of breast cancer
    • 10.1002/path.1691, 15641021
    • Simpson PT, Reis-Filho JS, Gale T, Lakhani SR. Molecular evolution of breast cancer. J Pathol 2005, 205(2):248-254. 10.1002/path.1691, 15641021.
    • (2005) J Pathol , vol.205 , Issue.2 , pp. 248-254
    • Simpson, P.T.1    Reis-Filho, J.S.2    Gale, T.3    Lakhani, S.R.4
  • 3
    • 0023910433 scopus 로고
    • Steroid receptors and other prognostic factors in primary breast cancer
    • Clark GM, McGuire WL. Steroid receptors and other prognostic factors in primary breast cancer. Semin Oncol 1988, 15(2 Suppl 1):20-25.
    • (1988) Semin Oncol , vol.15 , Issue.2 SUPPL 1 , pp. 20-25
    • Clark, G.M.1    McGuire, W.L.2
  • 5
    • 11244253900 scopus 로고    scopus 로고
    • Immunohistochemistry of estrogen and progesterone receptors reconsidered: experience with 5,993 breast cancers
    • 10.1309/4WV79N2GHJ3X1841, 15762276
    • Nadji M, Gomez-Fernandez C, Ganjei-Azar P, Morales AR. Immunohistochemistry of estrogen and progesterone receptors reconsidered: experience with 5,993 breast cancers. Am J Clin Pathol 2005, 123(1):21-27. 10.1309/4WV79N2GHJ3X1841, 15762276.
    • (2005) Am J Clin Pathol , vol.123 , Issue.1 , pp. 21-27
    • Nadji, M.1    Gomez-Fernandez, C.2    Ganjei-Azar, P.3    Morales, A.R.4
  • 6
    • 33847773775 scopus 로고    scopus 로고
    • Twenty-year follow-up of the Royal Marsden randomized, double-blinded tamoxifen breast cancer prevention trial
    • 10.1093/jnci/djk050, 17312305
    • Powles TJ, Ashley S, Tidy A, Smith IE, Dowsett M. Twenty-year follow-up of the Royal Marsden randomized, double-blinded tamoxifen breast cancer prevention trial. J Natl Cancer Inst 2007, 99(4):283-290. 10.1093/jnci/djk050, 17312305.
    • (2007) J Natl Cancer Inst , vol.99 , Issue.4 , pp. 283-290
    • Powles, T.J.1    Ashley, S.2    Tidy, A.3    Smith, I.E.4    Dowsett, M.5
  • 7
    • 34548144485 scopus 로고    scopus 로고
    • WITHDRAWN: Tamoxifen for early breast cancer
    • CD000486
    • Clarke MJ. WITHDRAWN: Tamoxifen for early breast cancer. Cochrane Database Syst Rev 2008, 4. CD000486.
    • (2008) Cochrane Database Syst Rev , vol.4
    • Clarke, M.J.1
  • 8
    • 0031471007 scopus 로고    scopus 로고
    • Acquired tamoxifen resistance in human breast cancer-potential mechanisms and clinical implications
    • 10.1097/00001813-199711000-00002, 9436634
    • Johnston SR. Acquired tamoxifen resistance in human breast cancer-potential mechanisms and clinical implications. Anticancer Drugs 1997, 8(10):911-930. 10.1097/00001813-199711000-00002, 9436634.
    • (1997) Anticancer Drugs , vol.8 , Issue.10 , pp. 911-930
    • Johnston, S.R.1
  • 9
    • 57649174634 scopus 로고    scopus 로고
    • MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer
    • 10.1074/jbc.M806041200, 2576549, 18790736
    • Zhao JJ, Lin J, Yang H, Kong W, He L, Ma X, Coppola D, Cheng JQ. MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer. J Biol Chem 2008, 283(45):31079-31086. 10.1074/jbc.M806041200, 2576549, 18790736.
    • (2008) J Biol Chem , vol.283 , Issue.45 , pp. 31079-31086
    • Zhao, J.J.1    Lin, J.2    Yang, H.3    Kong, W.4    He, L.5    Ma, X.6    Coppola, D.7    Cheng, J.Q.8
  • 10
    • 37249069903 scopus 로고    scopus 로고
    • Reversal of the estrogen receptor negative phenotype in breast cancer and restoration of antiestrogen response
    • 10.1158/1078-0432.CCR-07-0587, 18056179
    • Bayliss J, Hilger A, Vishnu P, Diehl K, El-Ashry D. Reversal of the estrogen receptor negative phenotype in breast cancer and restoration of antiestrogen response. Clin Cancer Res 2007, 13(23):7029-7036. 10.1158/1078-0432.CCR-07-0587, 18056179.
    • (2007) Clin Cancer Res , vol.13 , Issue.23 , pp. 7029-7036
    • Bayliss, J.1    Hilger, A.2    Vishnu, P.3    Diehl, K.4    El-Ashry, D.5
  • 12
    • 0030609203 scopus 로고    scopus 로고
    • Effects of vitamin D3 on proliferation of cancer cells in vitro
    • 10.1016/S0304-3835(97)00298-X, 9570387
    • Fife RS, Sledge GW, Proctor C. Effects of vitamin D3 on proliferation of cancer cells in vitro. Cancer Lett 1997, 120(1):65-69. 10.1016/S0304-3835(97)00298-X, 9570387.
    • (1997) Cancer Lett , vol.120 , Issue.1 , pp. 65-69
    • Fife, R.S.1    Sledge, G.W.2    Proctor, C.3
  • 13
    • 0030200377 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 induces morphological and biochemical markers of apoptosis in MCF-7 breast cancer cells
    • 10.1016/0960-0760(96)00055-6, 8903420
    • Simboli-Campbell M, Narvaez CJ, Tenniswood M, Welsh J. 1,25-Dihydroxyvitamin D3 induces morphological and biochemical markers of apoptosis in MCF-7 breast cancer cells. J Steroid Biochem Mol Biol 1996, 58(4):367-376. 10.1016/0960-0760(96)00055-6, 8903420.
    • (1996) J Steroid Biochem Mol Biol , vol.58 , Issue.4 , pp. 367-376
    • Simboli-Campbell, M.1    Narvaez, C.J.2    Tenniswood, M.3    Welsh, J.4
  • 16
    • 0031023922 scopus 로고    scopus 로고
    • Serum 1,25-dihydroxyvitamin D may be related inversely to disease activity in breast cancer patients with bone metastases
    • Mawer EB, Walls J, Howell A, Davies M, Ratcliffe WA, Bundred NJ. Serum 1,25-dihydroxyvitamin D may be related inversely to disease activity in breast cancer patients with bone metastases. J Clin Endocrinol Metab 1997, 82(1):118-122.
    • (1997) J Clin Endocrinol Metab , vol.82 , Issue.1 , pp. 118-122
    • Mawer, E.B.1    Walls, J.2    Howell, A.3    Davies, M.4    Ratcliffe, W.A.5    Bundred, N.J.6
  • 17
    • 84881227933 scopus 로고    scopus 로고
    • Associations between vitamin D deficiency and risk of aggressive breast cancer in African-American women
    • Yao S, Ambrosone CB. Associations between vitamin D deficiency and risk of aggressive breast cancer in African-American women. J Steroid Biochem Mol Biol 2012, 136:337-341.
    • (2012) J Steroid Biochem Mol Biol , vol.136 , pp. 337-341
    • Yao, S.1    Ambrosone, C.B.2
  • 18
    • 0026085480 scopus 로고
    • Immunocytochemical determination of estrogen receptor, progesterone receptor, and 1,25-dihydroxyvitamin D3 receptor in breast cancer and relationship to prognosis
    • Berger U, McClelland RA, Wilson P, Greene GL, Haussler MR, Pike JW, Colston K, Easton D, Coombes RC. Immunocytochemical determination of estrogen receptor, progesterone receptor, and 1,25-dihydroxyvitamin D3 receptor in breast cancer and relationship to prognosis. Cancer Res 1991, 51(1):239-244.
    • (1991) Cancer Res , vol.51 , Issue.1 , pp. 239-244
    • Berger, U.1    McClelland, R.A.2    Wilson, P.3    Greene, G.L.4    Haussler, M.R.5    Pike, J.W.6    Colston, K.7    Easton, D.8    Coombes, R.C.9
  • 20
    • 0033624178 scopus 로고    scopus 로고
    • 1alpha,25-Dihydroxyvitamin D3 down-regulates estrogen receptor abundance and suppresses estrogen actions in MCF-7 human breast cancer cells
    • Swami S, Krishnan AV, Feldman D. 1alpha,25-Dihydroxyvitamin D3 down-regulates estrogen receptor abundance and suppresses estrogen actions in MCF-7 human breast cancer cells. Clin Cancer Res 2000, 6(8):3371-3379.
    • (2000) Clin Cancer Res , vol.6 , Issue.8 , pp. 3371-3379
    • Swami, S.1    Krishnan, A.V.2    Feldman, D.3
  • 22
    • 0031031951 scopus 로고    scopus 로고
    • Comparative effects of 1,25(OH)2D3 and EB1089 on cell cycle kinetics and apoptosis in MCF-7 breast cancer cells
    • 10.1023/A:1005772432465, 9116316
    • Simboli-Campbell M, Narvaez CJ, van Weelden K, Tenniswood M, Welsh J. Comparative effects of 1,25(OH)2D3 and EB1089 on cell cycle kinetics and apoptosis in MCF-7 breast cancer cells. Breast Cancer Res Treat 1997, 42(1):31-41. 10.1023/A:1005772432465, 9116316.
    • (1997) Breast Cancer Res Treat , vol.42 , Issue.1 , pp. 31-41
    • Simboli-Campbell, M.1    Narvaez, C.J.2    van Weelden, K.3    Tenniswood, M.4    Welsh, J.5
  • 23
    • 0033573305 scopus 로고    scopus 로고
    • Regulation of estrogen receptor-alpha gene expression by 1, 25-dihydroxyvitamin D in MCF-7 cells
    • 10.1002/(SICI)1097-4644(19991215)75:4<640::AID-JCB10>3.0.CO;2-8, 10572247
    • Stoica A, Saceda M, Fakhro A, Solomon HB, Fenster BD, Martin MB. Regulation of estrogen receptor-alpha gene expression by 1, 25-dihydroxyvitamin D in MCF-7 cells. J Cell Biochem 1999, 75(4):640-651. 10.1002/(SICI)1097-4644(19991215)75:4<640::AID-JCB10>3.0.CO;2-8, 10572247.
    • (1999) J Cell Biochem , vol.75 , Issue.4 , pp. 640-651
    • Stoica, A.1    Saceda, M.2    Fakhro, A.3    Solomon, H.B.4    Fenster, B.D.5    Martin, M.B.6
  • 25
    • 0032403069 scopus 로고    scopus 로고
    • Propagation of genetically altered tumor cells derived from fine-needle aspirates of primary breast carcinoma
    • Li Z, Bustos V, Miner J, Paulo E, Meng ZH, Zlotnikov G, Ljung BM, Dairkee SH. Propagation of genetically altered tumor cells derived from fine-needle aspirates of primary breast carcinoma. Cancer Res 1998, 58(23):5271-5274.
    • (1998) Cancer Res , vol.58 , Issue.23 , pp. 5271-5274
    • Li, Z.1    Bustos, V.2    Miner, J.3    Paulo, E.4    Meng, Z.H.5    Zlotnikov, G.6    Ljung, B.M.7    Dairkee, S.H.8
  • 26
    • 0027396879 scopus 로고
    • Immunohistochemical determination of estrogen and progesterone receptor status in breast cancer
    • Tesch M, Shawwa A, Henderson R. Immunohistochemical determination of estrogen and progesterone receptor status in breast cancer. Am J Clin Pathol 1993, 99(1):8-12.
    • (1993) Am J Clin Pathol , vol.99 , Issue.1 , pp. 8-12
    • Tesch, M.1    Shawwa, A.2    Henderson, R.3
  • 27
    • 0035830865 scopus 로고    scopus 로고
    • The Wilms' tumor gene product (WT1) modulates the response to 1,25-dihydroxyvitamin D3 by induction of the vitamin D receptor
    • Maurer U, Jehan F, Englert C, Hubinger G, Weidmann E, DeLuca HF, Bergmann L. The Wilms' tumor gene product (WT1) modulates the response to 1,25-dihydroxyvitamin D3 by induction of the vitamin D receptor. Biol Chem 2001, 276(6):3727-3732.
    • (2001) Biol Chem , vol.276 , Issue.6 , pp. 3727-3732
    • Maurer, U.1    Jehan, F.2    Englert, C.3    Hubinger, G.4    Weidmann, E.5    DeLuca, H.F.6    Bergmann, L.7
  • 28
    • 79551647461 scopus 로고    scopus 로고
    • The cholesterol metabolite 25-hydroxycholesterol activates estrogen receptor alpha-mediated signaling in cancer cells and in cardiomyocytes
    • 10.1371/journal.pone.0016631, 3031608, 21304949
    • Lappano R, Recchia AG, De Francesco EM, Angelone T, Cerra MC, Picard D, Maggiolini M. The cholesterol metabolite 25-hydroxycholesterol activates estrogen receptor alpha-mediated signaling in cancer cells and in cardiomyocytes. PloS one 2011, 6(1):e16631. 10.1371/journal.pone.0016631, 3031608, 21304949.
    • (2011) PloS one , vol.6 , Issue.1
    • Lappano, R.1    Recchia, A.G.2    De Francesco, E.M.3    Angelone, T.4    Cerra, M.C.5    Picard, D.6    Maggiolini, M.7
  • 29
    • 33947406860 scopus 로고    scopus 로고
    • Developmental vitamin D deficiency alters brain protein expression in the adult rat: implications for neuropsychiatric disorders
    • 10.1002/pmic.200600392, 17295352
    • Almeras L, Eyles D, Benech P, Laffite D, Villard C, Patatian A, Boucraut J, Mackay-Sim A, McGrath J, Feron F. Developmental vitamin D deficiency alters brain protein expression in the adult rat: implications for neuropsychiatric disorders. Proteomics 2007, 7(5):769-780. 10.1002/pmic.200600392, 17295352.
    • (2007) Proteomics , vol.7 , Issue.5 , pp. 769-780
    • Almeras, L.1    Eyles, D.2    Benech, P.3    Laffite, D.4    Villard, C.5    Patatian, A.6    Boucraut, J.7    Mackay-Sim, A.8    McGrath, J.9    Feron, F.10
  • 30
    • 68549140038 scopus 로고    scopus 로고
    • Regulation of steroid receptor expression by 1alpha-hydroxyvitamin D5 in hormone-responsive breast cancer cells
    • Hussain-Hakimjee EA, Mehta RG. Regulation of steroid receptor expression by 1alpha-hydroxyvitamin D5 in hormone-responsive breast cancer cells. Anticancer Res 2009, 29(9):3555-3561.
    • (2009) Anticancer Res , vol.29 , Issue.9 , pp. 3555-3561
    • Hussain-Hakimjee, E.A.1    Mehta, R.G.2
  • 31
    • 37349122546 scopus 로고    scopus 로고
    • Estrogen stimulates transcription from the human prolactin distal promoter through AP1 and estrogen responsive elements in T47D human breast cancer cells
    • Duan R, Ginsburg E, Vonderhaar BK. Estrogen stimulates transcription from the human prolactin distal promoter through AP1 and estrogen responsive elements in T47D human breast cancer cells. Mol Cell Endocrinol 2008, 281(1-2):9-18.
    • (2008) Mol Cell Endocrinol , vol.281 , Issue.1-2 , pp. 9-18
    • Duan, R.1    Ginsburg, E.2    Vonderhaar, B.K.3
  • 32
    • 0027299883 scopus 로고
    • Growth factor, steroid, and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression
    • 359827, 8497271
    • Musgrove EA, Hamilton JA, Lee CS, Sweeney KJ, Watts CK, Sutherland RL. Growth factor, steroid, and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression. Mol Cell Biol 1993, 13(6):3577-3587. 359827, 8497271.
    • (1993) Mol Cell Biol , vol.13 , Issue.6 , pp. 3577-3587
    • Musgrove, E.A.1    Hamilton, J.A.2    Lee, C.S.3    Sweeney, K.J.4    Watts, C.K.5    Sutherland, R.L.6
  • 33
    • 0027956282 scopus 로고
    • Antiestrogen regulation of cell cycle progression and cyclin D1 gene expression in MCF-7 human breast cancer cells
    • 10.1007/BF00689680, 7981461
    • Watts CK, Sweeney KJ, Warlters A, Musgrove EA, Sutherland RL. Antiestrogen regulation of cell cycle progression and cyclin D1 gene expression in MCF-7 human breast cancer cells. Breast Cancer Res Treat 1994, 31(1):95-105. 10.1007/BF00689680, 7981461.
    • (1994) Breast Cancer Res Treat , vol.31 , Issue.1 , pp. 95-105
    • Watts, C.K.1    Sweeney, K.J.2    Warlters, A.3    Musgrove, E.A.4    Sutherland, R.L.5
  • 34
    • 48949116940 scopus 로고    scopus 로고
    • Eag1 as a cancer target
    • 10.1517/14728222.12.7.837, 18554152
    • Pardo LA, Suhmer W. Eag1 as a cancer target. Expert Opin Ther Targets 2008, 12(7):837-843. 10.1517/14728222.12.7.837, 18554152.
    • (2008) Expert Opin Ther Targets , vol.12 , Issue.7 , pp. 837-843
    • Pardo, L.A.1    Suhmer, W.2
  • 35
    • 0023873187 scopus 로고
    • Effects of a novel vitamin D analogue MC903 on cell proliferation and differentiation in vitro and on calcium metabolism in vivo
    • 10.1016/0006-2952(88)90177-3, 2830885
    • Binderup L, Bramm E. Effects of a novel vitamin D analogue MC903 on cell proliferation and differentiation in vitro and on calcium metabolism in vivo. Biochem Pharmacol 1988, 37(5):889-895. 10.1016/0006-2952(88)90177-3, 2830885.
    • (1988) Biochem Pharmacol , vol.37 , Issue.5 , pp. 889-895
    • Binderup, L.1    Bramm, E.2
  • 36
    • 0019198985 scopus 로고
    • The value of estrogen and progesterone receptors in the treatment of breast cancer
    • Osborne CK, Yochmowitz MG, Knight WA, McGuire WL. The value of estrogen and progesterone receptors in the treatment of breast cancer. Cancer 1980, 46(12 Suppl):2884-2888.
    • (1980) Cancer , vol.46 , Issue.12 SUPPL , pp. 2884-2888
    • Osborne, C.K.1    Yochmowitz, M.G.2    Knight, W.A.3    McGuire, W.L.4
  • 38
    • 0035208142 scopus 로고    scopus 로고
    • Minireview: genomic organization of the human ERalpha gene promoter region
    • Kos M, Reid G, Denger S, Gannon F. Minireview: genomic organization of the human ERalpha gene promoter region. Mol Endocrinol 2001, 15(12):2057-2063.
    • (2001) Mol Endocrinol , vol.15 , Issue.12 , pp. 2057-2063
    • Kos, M.1    Reid, G.2    Denger, S.3    Gannon, F.4
  • 40
    • 0028884216 scopus 로고
    • Growth factors in breast cancer
    • 10.1210/edrv-16-5-559, 8529572
    • Dickson RB, Lippman ME. Growth factors in breast cancer. Endocrine reviews 1995, 16(5):559-589. 10.1210/edrv-16-5-559, 8529572.
    • (1995) Endocrine reviews , vol.16 , Issue.5 , pp. 559-589
    • Dickson, R.B.1    Lippman, M.E.2
  • 41
    • 0026520381 scopus 로고
    • Growth regulation of estrogen receptor-negative breast cancer cells transfected with complementary DNAs for estrogen receptor
    • 10.1093/jnci/84.8.580, 1556769
    • Jiang SY, Jordan VC. Growth regulation of estrogen receptor-negative breast cancer cells transfected with complementary DNAs for estrogen receptor. J Natl Cancer Inst 1992, 84(8):580-591. 10.1093/jnci/84.8.580, 1556769.
    • (1992) J Natl Cancer Inst , vol.84 , Issue.8 , pp. 580-591
    • Jiang, S.Y.1    Jordan, V.C.2
  • 42
    • 0023617408 scopus 로고
    • Antiestrogens inhibit the mitogenic effect of growth factors on breast cancer cells in the total absence of estrogens
    • 10.1016/0006-291X(87)90819-9, 3304294
    • Vignon F, Bouton MM, Rochefort H. Antiestrogens inhibit the mitogenic effect of growth factors on breast cancer cells in the total absence of estrogens. Biochem Biophys Res Commun 1987, 146(3):1502-1508. 10.1016/0006-291X(87)90819-9, 3304294.
    • (1987) Biochem Biophys Res Commun , vol.146 , Issue.3 , pp. 1502-1508
    • Vignon, F.1    Bouton, M.M.2    Rochefort, H.3
  • 44
    • 38349046725 scopus 로고    scopus 로고
    • K + channel expression in human breast cancer cells: involvement in cell cycle regulation and carcinogenesis
    • 10.1007/s00232-007-9080-6, 18060344
    • Ouadid-Ahidouch H, Ahidouch A. K + channel expression in human breast cancer cells: involvement in cell cycle regulation and carcinogenesis. J Membr Biol 2008, 221(1):1-6. 10.1007/s00232-007-9080-6, 18060344.
    • (2008) J Membr Biol , vol.221 , Issue.1 , pp. 1-6
    • Ouadid-Ahidouch, H.1    Ahidouch, A.2
  • 45
    • 0037869395 scopus 로고    scopus 로고
    • Breast cell invasive potential relates to the myoepithelial phenotype
    • 10.1002/ijc.11172, 12794751
    • Gordon LA, Mulligan KT, Maxwell-Jones H, Adams M, Walker RA, Jones JL. Breast cell invasive potential relates to the myoepithelial phenotype. Int J Cancer 2003, 106(1):8-16. 10.1002/ijc.11172, 12794751.
    • (2003) Int J Cancer , vol.106 , Issue.1 , pp. 8-16
    • Gordon, L.A.1    Mulligan, K.T.2    Maxwell-Jones, H.3    Adams, M.4    Walker, R.A.5    Jones, J.L.6
  • 46
    • 18344389705 scopus 로고    scopus 로고
    • Vitamin D (3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling
    • 10.1083/jcb.200102028, 2150773, 11470825
    • Palmer HG, Gonzalez-Sancho JM, Espada J, Berciano MT, Puig I, Baulida J, Quintanilla M, Cano A, de Herreros AG, Lafarga M, Munoz A. Vitamin D (3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling. J Cell Biol 2001, 154(2):369-387. 10.1083/jcb.200102028, 2150773, 11470825.
    • (2001) J Cell Biol , vol.154 , Issue.2 , pp. 369-387
    • Palmer, H.G.1    Gonzalez-Sancho, J.M.2    Espada, J.3    Berciano, M.T.4    Puig, I.5    Baulida, J.6    Quintanilla, M.7    Cano, A.8    de Herreros, A.G.9    Lafarga, M.10    Munoz, A.11
  • 47
    • 0035875881 scopus 로고    scopus 로고
    • A Phase I trial of pulse calcitriol in patients with refractory malignancies: pulse dosing permits substantial dose escalation
    • 10.1002/1097-0142(20010615)91:12<2431::AID-CNCR1278>3.0.CO;2-3, 11413535
    • Beer TM, Munar M, Henner WD. A Phase I trial of pulse calcitriol in patients with refractory malignancies: pulse dosing permits substantial dose escalation. Cancer 2001, 91(12):2431-2439. 10.1002/1097-0142(20010615)91:12<2431::AID-CNCR1278>3.0.CO;2-3, 11413535.
    • (2001) Cancer , vol.91 , Issue.12 , pp. 2431-2439
    • Beer, T.M.1    Munar, M.2    Henner, W.D.3
  • 48
    • 33646564673 scopus 로고    scopus 로고
    • Promise of vitamin D analogues in the treatment of hyperproliferative conditions
    • 10.1158/1535-7163.MCT-05-0539, 16648549
    • Masuda S, Jones G. Promise of vitamin D analogues in the treatment of hyperproliferative conditions. Mol Cancer Ther 2006, 5(4):797-808. 10.1158/1535-7163.MCT-05-0539, 16648549.
    • (2006) Mol Cancer Ther , vol.5 , Issue.4 , pp. 797-808
    • Masuda, S.1    Jones, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.