Targeting CD44-STAT3 Signaling by Gemini Vitamin D Analog Leads to Inhibition of Invasion in Basal-Like Breast Cancer

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  So, Jae Young ^a,b   Smolarek, Amanda K ^a   Salerno, David M ^a   Maehr, Hubert ^a   Uskokovic, Milan ^a   Liu, Fang ^a,c,d   Suh, Nanjoo ^a,d  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c RUTGERS UNIVERSITY   (United States)

^d RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1ALPHA 25 DIHYDROXY 20 21 (3 HYDROXY 3 DEUTEROMETHYL 4,4,4 TRIDEUTEROBUTYL) 23 YNE 26,27 HEXAFLURO CHOLECALCIFEROL; ANTINEOPLASTIC AGENT; BXL 0124; HERMES ANTIGEN; JANUS KINASE 2; MATRIX METALLOPROTEINASE; MESSENGER RNA; SHORT HAIRPIN RNA; STAT3 PROTEIN; UNCLASSIFIED DRUG; UROKINASE; VITAMIN D DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BASAL LIKE BREAST CANCER; BIOLOGICAL ACTIVITY; CANCER INHIBITION; CANCER INVASION; CANCER SIZE; CELL LEVEL; CELL PROLIFERATION; COMPLEX FORMATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG TARGETING; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE INTERACTION; GENE REPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT;

ANIMALS; ANTIGENS, CD44; BREAST NEOPLASMS; CALCITRIOL; CELL LINE, TUMOR; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRANSPLANTATION, HETEROLOGOUS; VITAMIN D;

EID: 84872227268     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054020     Document Type: Article

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