메뉴 건너뛰기




Volumn 17, Issue 1, 2010, Pages

Molecular pathways mediating the anti-inflammatory effects of calcitriol: Implications for prostate cancer chemoprevention and treatment

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXYPROSTAGLANDIN DEHYDROGENASE; CALCITRIOL; CARBOPLATIN; CYCLOOXYGENASE 2; CYTOKINE; DEXAMETHASONE; DOCETAXEL; DOXERCALCIFEROL; ELOCALCITOL; IBUPROFEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 5; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PARICALCITOL; PLACEBO; PROSTAGLANDIN; ROFECOXIB; UNCLASSIFIED DRUG;

EID: 77449083534     PISSN: 13510088     EISSN: 14796821     Source Type: Journal    
DOI: 10.1677/ERC-09-0139     Document Type: Review
Times cited : (117)

References (186)
  • 5
    • 0347986573 scopus 로고    scopus 로고
    • Epidemiology and biology of insulin-like growth factor binding protein-3 (IGFBP-3) as an anti-cancer molecule
    • Ali O, Cohen P & Lee KW 2003 Epidemiology and biology of insulin-like growth factor binding protein-3 (IGFBP-3) as an anti-cancer molecule. Hormone and Metabolic Research 35 726-733.
    • (2003) Hormone and Metabolic Research , vol.35 , pp. 726-733
    • Ali, O.1    Cohen, P.2    Lee, K.W.3
  • 7
    • 34249825478 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and its relationship to inflammatory mediators
    • Angelo LS & Kurzrock R 2007 Vascular endothelial growth factor and its relationship to inflammatory mediators. Clinical Cancer Research 13 2825-2830.
    • (2007) Clinical Cancer Research , vol.13 , pp. 2825-2830
    • Angelo, L.S.1    Kurzrock, R.2
  • 8
    • 23244445988 scopus 로고    scopus 로고
    • Cyclooxygenase inhibition and cardiovascular risk
    • Antman EM, DeMets D & Loscalzo J 2005 Cyclooxygenase inhibition and cardiovascular risk. Circulation 112 759-770.
    • (2005) Circulation , vol.112 , pp. 759-770
    • Antman, E.M.1    DeMets, D.2    Loscalzo, J.3
  • 10
    • 42249098494 scopus 로고    scopus 로고
    • Randomized, double-blinded phase II evaluation of docetaxel with or without doxercalciferol in patients with metastatic, androgen-independent prostate cancer
    • Attia S, Eickhoff J, Wilding G, McNeel D, Blank J, Ahuja H, Jumonville A, Eastman M, Shevrin D, Glode M et al. 2008 Randomized, double-blinded phase II evaluation of docetaxel with or without doxercalciferol in patients with metastatic, androgen-independent prostate cancer. Clinical Cancer Research 14 2437-2443.
    • (2008) Clinical Cancer Research , vol.14 , pp. 2437-2443
    • Attia, S.1    Eickhoff, J.2    Wilding, G.3    McNeel, D.4    Blank, J.5    Ahuja, H.6    Jumonville, A.7    Eastman, M.8    Shevrin, D.9    Glode, M.10
  • 11
    • 0034051506 scopus 로고    scopus 로고
    • The role of prostaglandin synthesis in prostate cancer
    • Badawi AF 2000 The role of prostaglandin synthesis in prostate cancer. BJU International 85 451-462.
    • (2000) BJU International , vol.85 , pp. 451-462
    • Badawi, A.F.1
  • 12
    • 3042822267 scopus 로고    scopus 로고
    • Cancer and the chemokine network
    • Balkwill F 2004 Cancer and the chemokine network. Nature Reviews. Cancer 4 540-550.
    • (2004) Nature Reviews. Cancer , vol.4 , pp. 540-550
    • Balkwill, F.1
  • 15
    • 33747888063 scopus 로고    scopus 로고
    • 3 suppresses interleukin-8-mediated prostate cancer cell angiogenesis
    • 3 suppresses interleukin-8-mediated prostate cancer cell angiogenesis. Carcinogenesis 27 1883-1893.
    • (2006) Carcinogenesis , vol.27 , pp. 1883-1893
    • Bao, B.Y.1    Yao, J.2    Lee, Y.F.3
  • 16
    • 29744463149 scopus 로고    scopus 로고
    • 3 inhibits prostate cancer cell invasion via modulation of selective proteases
    • 3 inhibits prostate cancer cell invasion via modulation of selective proteases. Carcinogenesis 27 32-42.
    • (2006) Carcinogenesis , vol.27 , pp. 32-42
    • Bao, B.Y.1    Yeh, S.D.2    Lee, Y.F.3
  • 17
    • 33746641812 scopus 로고    scopus 로고
    • Calcitriol in the treatment of prostate cancer
    • Beer TM & Myrthue A 2006 Calcitriol in the treatment of prostate cancer. Anticancer Research 26 2647-2651.
    • (2006) Anticancer Research , vol.26 , pp. 2647-2651
    • Beer, T.M.1    Myrthue, A.2
  • 18
    • 0037372282 scopus 로고    scopus 로고
    • High-dose weekly oral calcitriol in patients with a rising PSA after prostatectomy or radiation for prostate carcinoma
    • Beer TM, Lemmon D, Lowe BA & Henner WD 2003 High-dose weekly oral calcitriol in patients with a rising PSA after prostatectomy or radiation for prostate carcinoma. Cancer 97 1217-1224.
    • (2003) Cancer , vol.97 , pp. 1217-1224
    • Beer, T.M.1    Lemmon, D.2    Lowe, B.A.3    Henner, W.D.4
  • 22
    • 85047685002 scopus 로고    scopus 로고
    • Antiproliferative effects of 1alpha,25-dihydroxyvitamin D(3) and vitamin D analogs on tumor-derived endothelial cells
    • Bernardi RJ, Johnson CS, Modzelewski RA & Trump DL 2002 Antiproliferative effects of 1alpha,25-dihydroxyvitamin D(3) and vitamin D analogs on tumor-derived endothelial cells. Endocrinology 143 2508-2514.
    • (2002) Endocrinology , vol.143 , pp. 2508-2514
    • Bernardi, R.J.1    Johnson, C.S.2    Modzelewski, R.A.3    Trump, D.L.4
  • 23
    • 31444438397 scopus 로고    scopus 로고
    • Achieving treatment goals for hormone-refractory prostate cancer with chemotherapy
    • Berry W & Eisenberger M 2005 Achieving treatment goals for hormone-refractory prostate cancer with chemotherapy. Oncologist 10 (Suppl 3) 30-39.
    • (2005) Oncologist , vol.10 , Issue.SUPPL. 3 , pp. 30-39
    • Berry, W.1    Eisenberger, M.2
  • 24
    • 0030910440 scopus 로고    scopus 로고
    • 3 and 9-cis-retinoic acid act synergistically to inhibit the growth of LNCaP prostate cells and cause accumulation of cells in G1
    • 3 and 9-cis-retinoic acid act synergistically to inhibit the growth of LNCaP prostate cells and cause accumulation of cells in G1. Endocrinology 138 1491-1497.
    • (1997) Endocrinology , vol.138 , pp. 1491-1497
    • Blutt, S.E.1    Allegretto, E.A.2    Pike, J.W.3    Weigel, N.L.4
  • 25
    • 0034463114 scopus 로고    scopus 로고
    • Calcitriol-induced apoptosis in LNCaP cells is blocked by overexpression of Bcl-2
    • Blutt SE, McDonnell TJ, Polek TC & Weigel NL 2000 Calcitriol-induced apoptosis in LNCaP cells is blocked by overexpression of Bcl-2. Endocrinology 141 10-17.
    • (2000) Endocrinology , vol.141 , pp. 10-17
    • Blutt, S.E.1    McDonnell, T.J.2    Polek, T.C.3    Weigel, N.L.4
  • 27
    • 0035093741 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-3 mediates 1 alpha,25-dihydroxyvitamin D(3) growth inhibition in the LNCaP prostate cancer cell line through p21/WAF1
    • Boyle BJ, Zhao XY, Cohen P & Feldman D 2001 Insulin-like growth factor binding protein-3 mediates 1 alpha,25-dihydroxyvitamin D(3) growth inhibition in the LNCaP prostate cancer cell line through p21/WAF1. Journal of Urology 165 1319-1324.
    • (2001) Journal of Urology , vol.165 , pp. 1319-1324
    • Boyle, B.J.1    Zhao, X.Y.2    Cohen, P.3    Feldman, D.4
  • 30
    • 0035504081 scopus 로고    scopus 로고
    • Transcriptional regulation of bcl-2 by nuclear factor kappa B and its significance in prostate cancer
    • Catz SD & Johnson JL 2001 Transcriptional regulation of bcl-2 by nuclear factor kappa B and its significance in prostate cancer. Oncogene 20 7342-7351.
    • (2001) Oncogene , vol.20 , pp. 7342-7351
    • Catz, S.D.1    Johnson, J.L.2
  • 31
    • 56649111518 scopus 로고    scopus 로고
    • A phase II study of high-dose calcitriol combined with mitoxantrone and prednisone for androgen-independent prostate cancer
    • Chan JS, Beer TM, Quinn DI, Pinski JK, Garzotto M, Sokoloff M, Dehaze DR & Ryan CW 2008 A phase II study of high-dose calcitriol combined with mitoxantrone and prednisone for androgen-independent prostate cancer. BJU International 102 1601-1606.
    • (2008) BJU International , vol.102 , pp. 1601-1606
    • Chan, J.S.1    Beer, T.M.2    Quinn, D.I.3    Pinski, J.K.4    Garzotto, M.5    Sokoloff, M.6    Dehaze, D.R.7    Ryan, C.W.8
  • 34
    • 0033623858 scopus 로고    scopus 로고
    • 2 and the protein kinase A pathway mediate arachidonic acid induction of c-fos in human prostate cancer cell
    • 2 and the protein kinase A pathway mediate arachidonic acid induction of c-fos in human prostate cancer cell. British Journal of Cancer 82 2000-2006.
    • (2000) British Journal of Cancer , vol.82 , pp. 2000-2006
    • Chen, Y.1    Hughes-Fulford, M.2
  • 37
    • 59149094862 scopus 로고    scopus 로고
    • Role of vitamin D receptor in the antiproliferative effects of calcitriol in tumorderived endothelial cells and tumor angiogenesis in vivo
    • Chung I, Han G, Seshadri M, Gillard BM, Yu WD, Foster BA, Trump DL & Johnson CS 2009 Role of vitamin D receptor in the antiproliferative effects of calcitriol in tumorderived endothelial cells and tumor angiogenesis in vivo. Cancer Research 69 967-975.
    • (2009) Cancer Research , vol.69 , pp. 967-975
    • Chung, I.1    Han, G.2    Seshadri, M.3    Gillard, B.M.4    Yu, W.D.5    Foster, B.A.6    Trump, D.L.7    Johnson, C.S.8
  • 41
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens LM & Werb Z 2002 Inflammation and cancer. Nature 420 860-867.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 43
    • 0141645610 scopus 로고    scopus 로고
    • Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation
    • Criswell T, Leskov K, Miyamoto S, Luo G & Boothman DA 2003 Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation. Oncogene 22 5813-5827.
    • (2003) Oncogene , vol.22 , pp. 5813-5827
    • Criswell, T.1    Leskov, K.2    Miyamoto, S.3    Luo, G.4    Boothman, D.A.5
  • 45
    • 34548202165 scopus 로고    scopus 로고
    • Vitamin D signalling pathways in cancer: Potential for anticancer therapeutics
    • Deeb KK, Trump DL & Johnson CS 2007 Vitamin D signalling pathways in cancer: potential for anticancer therapeutics. Nature Reviews. Cancer 7 684-700.
    • (2007) Nature Reviews. Cancer , vol.7 , pp. 684-700
    • Deeb, K.K.1    Trump, D.L.2    Johnson, C.S.3
  • 46
    • 0032805744 scopus 로고    scopus 로고
    • Proliferative inflammatory atrophy of the prostate: Implications for prostatic carcinogenesis
    • De Marzo AM, Marchi VL, Epstein JI & Nelson WG 1999 Proliferative inflammatory atrophy of the prostate: implications for prostatic carcinogenesis. American Journal of Pathology 155 1985-1992.
    • (1999) American Journal of Pathology , vol.155 , pp. 1985-1992
    • De Marzo, A.M.1    Marchi, V.L.2    Epstein, J.I.3    Nelson, W.G.4
  • 51
    • 0034875454 scopus 로고    scopus 로고
    • Low levels of prostate-specific antigen predict long-term risk of prostate cancer: Results from the Baltimore Longitudinal Study of Aging
    • Fang J, Metter EJ, Landis P, Chan DW, Morrell CH & Carter HB 2001 Low levels of prostate-specific antigen predict long-term risk of prostate cancer: results from the Baltimore Longitudinal Study of Aging. Urology 58 411-416.
    • (2001) Urology , vol.58 , pp. 411-416
    • Fang, J.1    Metter, E.J.2    Landis, P.3    Chan, D.W.4    Morrell, C.H.5    Carter, H.B.6
  • 52
    • 84884080872 scopus 로고    scopus 로고
    • Vitamin D: Biology, action and clinical implications
    • Eds R Marcus, D Feldman, DA Nelson & CJ Rosen. San Diego: Academic Press
    • Feldman D, Malloy PJ, Krishnan AV & Balint E 2007 Vitamin D: biology, action and clinical implications. In Osteoporosis, pp 317-382. Eds R Marcus, D Feldman, DA Nelson & CJ Rosen. San Diego: Academic Press.
    • (2007) Osteoporosis , pp. 317-382
    • Feldman, D.1    Malloy, P.J.2    Krishnan, A.V.3    Balint, E.4
  • 54
    • 33745828343 scopus 로고    scopus 로고
    • A phase II, trial of dexamethasone, vitamin D, and carboplatin in patients with hormonerefractory prostate cancer
    • Flaig TW, Barqawi A, Miller G, Kane M, Zeng C, Crawford ED & Glode LM 2006 A phase II, trial of dexamethasone, vitamin D, and carboplatin in patients with hormonerefractory prostate cancer. Cancer 107 266-274.
    • (2006) Cancer , vol.107 , pp. 266-274
    • Flaig, T.W.1    Barqawi, A.2    Miller, G.3    Kane, M.4    Zeng, C.5    Crawford, E.D.6    Glode, L.M.7
  • 55
    • 56049098150 scopus 로고    scopus 로고
    • Molecular actions of vitamin D contributing to cancer prevention
    • Fleet JC 2008 Molecular actions of vitamin D contributing to cancer prevention. Molecular Aspects of Medicine 29 388-396.
    • (2008) Molecular Aspects of Medicine , vol.29 , pp. 388-396
    • Fleet, J.C.1
  • 56
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • Folkman J 1995 Angiogenesis in cancer, vascular, rheumatoid and other disease. Nature Medicine 1 27-31.
    • (1995) Nature Medicine , vol.1 , pp. 27-31
    • Folkman, J.1
  • 58
    • 0038375038 scopus 로고    scopus 로고
    • Vascular endothelial growth factor gene expression in colon cancer cells exposed to prostaglandin E2 is mediated by hypoxiainducible factor 1
    • Fukuda R, Kelly B & Semenza GL 2003 Vascular endothelial growth factor gene expression in colon cancer cells exposed to prostaglandin E2 is mediated by hypoxiainducible factor 1. Cancer Research 63 2330-2334.
    • (2003) Cancer Research , vol.63 , pp. 2330-2334
    • Fukuda, R.1    Kelly, B.2    Semenza, G.L.3
  • 63
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the NF-kappaB puzzle
    • Ghosh S & Karin M 2002 Missing pieces in the NF-kappaB puzzle. Cell 109 Suppl S81-S96.
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • Ghosh, S.1    Karin, M.2
  • 65
    • 4043060025 scopus 로고    scopus 로고
    • A vitamin D analog down-regulates proinflammatory chemokine production by pancreatic islets inhibiting T cell recruitment and type 1 diabetes development
    • Giarratana N, Penna G, Amuchastegui S, Mariani R, Daniel KC & Adorini L 2004 A vitamin D analog down-regulates proinflammatory chemokine production by pancreatic islets inhibiting T cell recruitment and type 1 diabetes development. Journal of Immunology 173 2280-2287.
    • (2004) Journal of Immunology , vol.173 , pp. 2280-2287
    • Giarratana, N.1    Penna, G.2    Amuchastegui, S.3    Mariani, R.4    Daniel, K.C.5    Adorini, L.6
  • 66
    • 18844409137 scopus 로고    scopus 로고
    • The epidemiology of vitamin D and cancer incidence and mortality: A review (United States)
    • Giovannucci E 2005 The epidemiology of vitamin D and cancer incidence and mortality: a review (United States). Cancer Causes and Control 16 83-95.
    • (2005) Cancer Causes and Control , vol.16 , pp. 83-95
    • Giovannucci, E.1
  • 68
    • 33745305794 scopus 로고    scopus 로고
    • Knock-down of the cytoprotective gene, clusterin, to enhance hormone and chemosensitivity in prostate and other cancers
    • Gleave M & Chi KN 2005 Knock-down of the cytoprotective gene, clusterin, to enhance hormone and chemosensitivity in prostate and other cancers. Annals of New York Academy of Sciences 1058 1-15.
    • (2005) Annals of New York Academy of Sciences , vol.1058 , pp. 1-15
    • Gleave, M.1    Chi, K.N.2
  • 70
    • 33746655489 scopus 로고    scopus 로고
    • Vitamin D compounds: Activity against microbes and cancer
    • Gombart AF, Luong QT & Koeffler HP 2006 Vitamin D compounds: activity against microbes and cancer. Anticancer Research 26 2531-2542.
    • (2006) Anticancer Research , vol.26 , pp. 2531-2542
    • Gombart, A.F.1    Luong, Q.T.2    Koeffler, H.P.3
  • 71
    • 13444263619 scopus 로고    scopus 로고
    • Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and non-selective non-steroidal anti-inflammatory drugs: Nested case-control study
    • Graham DJ, Campen D, Hui R, Spence M, Cheetham C, Levy G, Shoor S & Ray WA 2005 Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and non-selective non-steroidal anti-inflammatory drugs: nested case-control study. Lancet 365 475-481.
    • (2005) Lancet , vol.365 , pp. 475-481
    • Graham, D.J.1    Campen, D.2    Hui, R.3    Spence, M.4    Cheetham, C.5    Levy, G.6    Shoor, S.7    Ray, W.A.8
  • 73
    • 0033988665 scopus 로고    scopus 로고
    • Over-expression of cyclooxygenase-2 in human prostate adenocarcinoma
    • Gupta S, Srivastava M, Ahmad N, Bostwick DG & Mukhtar H 2000 Over-expression of cyclooxygenase-2 in human prostate adenocarcinoma. Prostate 42 73-78.
    • (2000) Prostate , vol.42 , pp. 73-78
    • Gupta, S.1    Srivastava, M.2    Ahmad, N.3    Bostwick, D.G.4    Mukhtar, H.5
  • 74
    • 2342625403 scopus 로고    scopus 로고
    • Suppression of prostate carcinogenesis by dietary supplementation of celecoxib in transgenic adenocarcinoma of the mouse prostate model
    • Gupta S, Adhami VM, Subbarayan M, MacLennan GT, Lewin JS, Hafeli UO, Fu P & Mukhtar H 2004 Suppression of prostate carcinogenesis by dietary supplementation of celecoxib in transgenic adenocarcinoma of the mouse prostate model. Cancer Research 64 3334-3343.
    • (2004) Cancer Research , vol.64 , pp. 3334-3343
    • Gupta, S.1    Adhami, V.M.2    Subbarayan, M.3    MacLennan, G.T.4    Lewin, J.S.5    Hafeli, U.O.6    Fu, P.7    Mukhtar, H.8
  • 75
    • 0026447217 scopus 로고
    • Geographic patterns of prostate cancer mortality. Evidence for a protective effect of ultraviolet radiation
    • Hanchette CL & Schwartz GG 1992 Geographic patterns of prostate cancer mortality. Evidence for a protective effect of ultraviolet radiation. Cancer 70 2861-2869.
    • (1992) Cancer , vol.70 , pp. 2861-2869
    • Hanchette, C.L.1    Schwartz, G.G.2
  • 76
    • 0031595760 scopus 로고    scopus 로고
    • 3 decreases DNA binding of nuclear factor-kappaB in human fibroblasts
    • 3 decreases DNA binding of nuclear factor-kappaB in human fibroblasts. FEBS Letters 436 329-334.
    • (1998) FEBS Letters , vol.436 , pp. 329-334
    • Harant, H.1    Wolff, B.2    Lindley, I.J.3
  • 79
    • 0035849720 scopus 로고    scopus 로고
    • Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis
    • Huang S, Pettaway CA, Uehara H, Bucana CD & Fidler IJ 2001 Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis. Oncogene 20 4188-4197.
    • (2001) Oncogene , vol.20 , pp. 4188-4197
    • Huang, S.1    Pettaway, C.A.2    Uehara, H.3    Bucana, C.D.4    Fidler, I.J.5
  • 80
    • 0345505237 scopus 로고    scopus 로고
    • Cyclooxygenase-2 and prostate carcinogenesis
    • Hussain T, Gupta S & Mukhtar H 2003 Cyclooxygenase-2 and prostate carcinogenesis. Cancer Letters 191 125-135.
    • (2003) Cancer Letters , vol.191 , pp. 125-135
    • Hussain, T.1    Gupta, S.2    Mukhtar, H.3
  • 81
    • 0842327809 scopus 로고    scopus 로고
    • Expression of NF-kappaB in prostate cancer lymph node metastases
    • Ismail HA, Lessard L, Mes-Masson AM & Saad F 2004 Expression of NF-kappaB in prostate cancer lymph node metastases. Prostate 58 308-313.
    • (2004) Prostate , vol.58 , pp. 308-313
    • Ismail, H.A.1    Lessard, L.2    Mes-Masson, A.M.3    Saad, F.4
  • 83
    • 0034742488 scopus 로고    scopus 로고
    • Inhibitory effects of 1alpha,25-dihydroxyvitamin D(3) on the G(1)-S phase-controlling machinery
    • Jensen SS, Madsen MW, Lukas J, Binderup L & Bartek J 2001 Inhibitory effects of 1alpha,25-dihydroxyvitamin D(3) on the G(1)-S phase-controlling machinery. Molecular Endocrinology 15 1370-1380.
    • (2001) Molecular Endocrinology , vol.15 , pp. 1370-1380
    • Jensen, S.S.1    Madsen, M.W.2    Lukas, J.3    Binderup, L.4    Bartek, J.5
  • 84
  • 86
    • 22144475857 scopus 로고    scopus 로고
    • Recent progress in management of advanced prostate cancer
    • Kantoff P 2005 Recent progress in management of advanced prostate cancer. Oncology 19 631-636.
    • (2005) Oncology , vol.19 , pp. 631-636
    • Kantoff, P.1
  • 87
    • 0036009115 scopus 로고    scopus 로고
    • NF-kappaB at the crossroads of life and death
    • Karin M & Lin A 2002 NF-kappaB at the crossroads of life and death. Nature Immunology 3 221-227.
    • (2002) Nature Immunology , vol.3 , pp. 221-227
    • Karin, M.1    Lin, A.2
  • 88
    • 0033119240 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha sensitizes prostate cancer cells to gamma-irradiation-induced apoptosis
    • Kimura K, Bowen C, Spiegel S & Gelmann EP 1999 Tumor necrosis factor-alpha sensitizes prostate cancer cells to gamma-irradiation-induced apoptosis. Cancer Research 59 1606-1614.
    • (1999) Cancer Research , vol.59 , pp. 1606-1614
    • Kimura, K.1    Bowen, C.2    Spiegel, S.3    Gelmann, E.P.4
  • 90
    • 8844273350 scopus 로고    scopus 로고
    • Inhibition of prostate cancer growth by vitamin D: Regulation of target gene expression
    • Krishnan AV, Peehl DM & Feldman D 2003 Inhibition of prostate cancer growth by vitamin D: regulation of target gene expression. Journal of Cellular Biochemistry 88 363-371.
    • (2003) Journal of Cellular Biochemistry , vol.88 , pp. 363-371
    • Krishnan, A.V.1    Peehl, D.M.2    Feldman, D.3
  • 91
    • 1942443627 scopus 로고    scopus 로고
    • Analysis of vitamin D-regulated gene expression in LNCaP human prostate cancer cells using cDNA microarrays
    • Krishnan AV, Shinghal R, Raghavachari N, Brooks JD, Peehl DM & Feldman D 2004 Analysis of vitamin D-regulated gene expression in LNCaP human prostate cancer cells using cDNA microarrays. Prostate 59 243-251.
    • (2004) Prostate , vol.59 , pp. 243-251
    • Krishnan, A.V.1    Shinghal, R.2    Raghavachari, N.3    Brooks, J.D.4    Peehl, D.M.5    Feldman, D.6
  • 93
  • 94
    • 79951970236 scopus 로고    scopus 로고
    • Inhibition of prostaglandin synthesis and actions contributes to the beneficial effects of calcitriol in prostate cancer
    • Krishnan AV, Srinivas S & Feldman D 2009 Inhibition of prostaglandin synthesis and actions contributes to the beneficial effects of calcitriol in prostate cancer. Dermato-Endocrinology 1 1-5.
    • (2009) Dermato-Endocrinology , vol.1 , pp. 1-5
    • Krishnan, A.V.1    Srinivas, S.2    Feldman, D.3
  • 95
    • 47849098044 scopus 로고    scopus 로고
    • Inflammation: Gearing the journey to cancer
    • Kundu JK & Surh YJ 2008 Inflammation: gearing the journey to cancer. Mutation Research 659 15-30.
    • (2008) Mutation Research , vol.659 , pp. 15-30
    • Kundu, J.K.1    Surh, Y.J.2
  • 96
    • 18544382644 scopus 로고    scopus 로고
    • C-reactive protein is significantly associated with prostate-specific antigen and metastatic disease in prostate cancer
    • Lehrer S, Diamond EJ, Mamkine B, Droller MJ, Stone NN & Stock RG 2005 C-reactive protein is significantly associated with prostate-specific antigen and metastatic disease in prostate cancer. BJU International 95 961-962.
    • (2005) BJU International , vol.95 , pp. 961-962
    • Lehrer, S.1    Diamond, E.J.2    Mamkine, B.3    Droller, M.J.4    Stone, N.N.5    Stock, R.G.6
  • 97
    • 27644466358 scopus 로고    scopus 로고
    • Nuclear localisation of nuclear factor-kappaB transcription factors in prostate cancer: An immunohistochemical study
    • Lessard L, Begin LR, Gleave ME, Mes-Masson AM & Saad F 2005 Nuclear localisation of nuclear factor-kappaB transcription factors in prostate cancer: an immunohistochemical study. British Journal of Cancer 93 1019-1023.
    • (2005) British Journal of Cancer , vol.93 , pp. 1019-1023
    • Lessard, L.1    Begin, L.R.2    Gleave, M.E.3    Mes-Masson, A.M.4    Saad, F.5
  • 99
    • 0001501848 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase-2 suppresses angiogenesis and the growth of prostate cancer in vivo
    • Liu XH, Kirschenbaum A, Yao S, Lee R, Holland JF & Levine AC 2000 Inhibition of cyclooxygenase-2 suppresses angiogenesis and the growth of prostate cancer in vivo. Journal of Urology 164 820-825.
    • (2000) Journal of Urology , vol.164 , pp. 820-825
    • Liu, X.H.1    Kirschenbaum, A.2    Yao, S.3    Lee, R.4    Holland, J.F.5    Levine, A.C.6
  • 100
    • 0037146555 scopus 로고    scopus 로고
    • Prostaglandin E2 induces hypoxia-inducible factor-1alpha stabilization and nuclear localization in a human prostate cancer cell line
    • Liu XH, Kirschenbaum A, Lu M, Yao S, Dosoretz A, Holland JF & Levine AC 2002 Prostaglandin E2 induces hypoxia-inducible factor-1alpha stabilization and nuclear localization in a human prostate cancer cell line. Journal of Biological Chemistry 277 50081-50086.
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 50081-50086
    • Liu, X.H.1    Kirschenbaum, A.2    Lu, M.3    Yao, S.4    Dosoretz, A.5    Holland, J.F.6    Levine, A.C.7
  • 102
    • 31944436853 scopus 로고    scopus 로고
    • Baseline prostate-specific antigen compared with median prostate-specific antigen for age group as predictor of prostate cancer risk in men younger than 60 years old
    • Loeb S, Roehl KA, Antenor JA, Catalona WJ, Suarez BK & Nadler RB 2006 Baseline prostate-specific antigen compared with median prostate-specific antigen for age group as predictor of prostate cancer risk in men younger than 60 years old. Urology 67 316-320.
    • (2006) Urology , vol.67 , pp. 316-320
    • Loeb, S.1    Roehl, K.A.2    Antenor, J.A.3    Catalona, W.J.4    Suarez, B.K.5    Nadler, R.B.6
  • 103
    • 0347129619 scopus 로고    scopus 로고
    • Inflammation as a target for prostate cancer chemoprevention: Pathological and laboratory rationale
    • Lucia MS & Torkko KC 2004 Inflammation as a target for prostate cancer chemoprevention: pathological and laboratory rationale. Journal of Urology 171 S30-S34.
    • (2004) Journal of Urology , vol.171
    • Lucia, M.S.1    Torkko, K.C.2
  • 105
    • 43649109029 scopus 로고    scopus 로고
    • Inflammation and cancer: Role of nuclear factor-kappaB activation
    • Maeda S & Omata M 2008 Inflammation and cancer: role of nuclear factor-kappaB activation. Cancer Science 99 836-842.
    • (2008) Cancer Science , vol.99 , pp. 836-842
    • Maeda, S.1    Omata, M.2
  • 106
    • 33749025562 scopus 로고    scopus 로고
    • Pre-clinical evidence and clinical translation of benign prostatic hyperplasia treatment by the vitamin D receptor agonist BXL-628 (elocalcitol)
    • Maggi M, Crescioli C, Morelli A, Colli E & Adorini L 2006 Pre-clinical evidence and clinical translation of benign prostatic hyperplasia treatment by the vitamin D receptor agonist BXL-628 (elocalcitol). Journal of Endocrinological Investigation 29 665-674.
    • (2006) Journal of Endocrinological Investigation , vol.29 , pp. 665-674
    • Maggi, M.1    Crescioli, C.2    Morelli, A.3    Colli, E.4    Adorini, L.5
  • 110
    • 34249711291 scopus 로고    scopus 로고
    • Aspirin and colon cancer - targeting prevention?
    • Markowitz SD 2007 Aspirin and colon cancer - targeting prevention? New England Journal of Medicine 356 2195-2198.
    • (2007) New England Journal of Medicine , vol.356 , pp. 2195-2198
    • Markowitz, S.D.1
  • 111
    • 33646564673 scopus 로고    scopus 로고
    • Promise of vitamin D analogues in the treatment of hyperproliferative conditions
    • Masuda S & Jones G 2006 Promise of vitamin D analogues in the treatment of hyperproliferative conditions. Molecular Cancer Therapeutics 5 797-808.
    • (2006) Molecular Cancer Therapeutics , vol.5 , pp. 797-808
    • Masuda, S.1    Jones, G.2
  • 113
    • 9244221653 scopus 로고    scopus 로고
    • Targeting multiple signaling pathways as a strategy for managing prostate cancer: Multifocal signal modulation therapy
    • McCarty MF 2004 Targeting multiple signaling pathways as a strategy for managing prostate cancer: multifocal signal modulation therapy. Integrative Cancer Therapies 3 349-380.
    • (2004) Integrative Cancer Therapies , vol.3 , pp. 349-380
    • McCarty, M.F.1
  • 116
  • 117
    • 24744452645 scopus 로고    scopus 로고
    • Regulation of prostaglandin metabolism by calcitriol attenuates growth stimulation in prostate cancer cells
    • Moreno J, Krishnan AV, Swami S, Nonn L, Peehl DM & Feldman D 2005 Regulation of prostaglandin metabolism by calcitriol attenuates growth stimulation in prostate cancer cells. Cancer Research 65 7917-7925.
    • (2005) Cancer Research , vol.65 , pp. 7917-7925
    • Moreno, J.1    Krishnan, A.V.2    Swami, S.3    Nonn, L.4    Peehl, D.M.5    Feldman, D.6
  • 119
    • 33745063595 scopus 로고    scopus 로고
    • RNA interference-mediated cyclooxygenase-2 inhibition prevents prostate cancer cell growth and induces differentiation: Modulation of neuronal protein synaptophysin, cyclin D1, and androgen receptor
    • Narayanan BA, Narayanan NK, Davis L & Nargi D 2006 RNA interference-mediated cyclooxygenase-2 inhibition prevents prostate cancer cell growth and induces differentiation: modulation of neuronal protein synaptophysin, cyclin D1, and androgen receptor. Molecular Cancer Therapeutics 5 1117-1125.
    • (2006) Molecular Cancer Therapeutics , vol.5 , pp. 1117-1125
    • Narayanan, B.A.1    Narayanan, N.K.2    Davis, L.3    Nargi, D.4
  • 120
    • 58849123796 scopus 로고    scopus 로고
    • Inflammatory processes of prostate tissue microenvironment drive rat prostate carcinogenesis: Preventive effects of celecoxib
    • Narayanan NK, Nargi D, Horton L, Reddy BS, Bosland MC & Narayanan BA 2009 Inflammatory processes of prostate tissue microenvironment drive rat prostate carcinogenesis: preventive effects of celecoxib. Prostate 69 133-141.
    • (2009) Prostate , vol.69 , pp. 133-141
    • Narayanan, N.K.1    Nargi, D.2    Horton, L.3    Reddy, B.S.4    Bosland, M.C.5    Narayanan, B.A.6
  • 123
    • 33646228153 scopus 로고    scopus 로고
    • Inhibition of p38 by vitamin D reduces interleukin-6 production in normal prostate cells via mitogen-activated protein kinase phosphatase 5: Implications for prostate cancer prevention by vitamin D
    • Nonn L, Peng L, Feldman D & Peehl DM 2006 Inhibition of p38 by vitamin D reduces interleukin-6 production in normal prostate cells via mitogen-activated protein kinase phosphatase 5: implications for prostate cancer prevention by vitamin D. Cancer Research 66 4516-4524.
    • (2006) Cancer Research , vol.66 , pp. 4516-4524
    • Nonn, L.1    Peng, L.2    Feldman, D.3    Peehl, D.M.4
  • 124
    • 0036380878 scopus 로고    scopus 로고
    • Vitamin D and systemic cancer: Is this relevant to malignant melanoma?
    • Osborne JE & Hutchinson PE 2002 Vitamin D and systemic cancer: is this relevant to malignant melanoma? British Journal of Dermatology 147 197-213.
    • (2002) British Journal of Dermatology , vol.147 , pp. 197-213
    • Osborne, J.E.1    Hutchinson, P.E.2
  • 125
    • 0033517999 scopus 로고    scopus 로고
    • Constitutive activation of IkappaB kinase alpha and NF-kappaB in prostate cancer cells is inhibited by ibuprofen
    • Palayoor ST, Youmell MY, Calderwood SK, Coleman CN & Price BD 1999 Constitutive activation of IkappaB kinase alpha and NF-kappaB in prostate cancer cells is inhibited by ibuprofen. Oncogene 18 7389-7394.
    • (1999) Oncogene , vol.18 , pp. 7389-7394
    • Palayoor, S.T.1    Youmell, M.Y.2    Calderwood, S.K.3    Coleman, C.N.4    Price, B.D.5
  • 126
    • 0042303832 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 activates interleukin-6 expression in prostate cancer cells through the synergistic collaboration of the Smad2, p38-NF-kappaB, JNK, and Ras signaling pathways
    • Park JI, Lee MG, Cho K, Park BJ, Chae KS, Byun DS, Ryu BK, Park YK & Chi SG 2003 Transforming growth factor-beta1 activates interleukin-6 expression in prostate cancer cells through the synergistic collaboration of the Smad2, p38-NF-kappaB, JNK, and Ras signaling pathways. Oncogene 22 4314-4332.
    • (2003) Oncogene , vol.22 , pp. 4314-4332
    • Park, J.I.1    Lee, M.G.2    Cho, K.3    Park, B.J.4    Chae, K.S.5    Byun, D.S.6    Ryu, B.K.7    Park, Y.K.8    Chi, S.G.9
  • 128
    • 2342506601 scopus 로고    scopus 로고
    • Identification of a functional Vitamin D response element in the human insulin-like growth factor binding protein-3 promoter
    • Peng L, Malloy PJ & Feldman D 2004 Identification of a functional Vitamin D response element in the human insulin-like growth factor binding protein-3 promoter. Molecular Endocrinology 18 1109-1119.
    • (2004) Molecular Endocrinology , vol.18 , pp. 1109-1119
    • Peng, L.1    Malloy, P.J.2    Feldman, D.3
  • 129
    • 37349007890 scopus 로고    scopus 로고
    • The role of insulin-like growth factor binding protein-3 in the growth inhibitory actions of androgens in LNCaP human prostate cancer cells
    • Peng L, Wang J, Malloy PJ & Feldman D 2008 The role of insulin-like growth factor binding protein-3 in the growth inhibitory actions of androgens in LNCaP human prostate cancer cells. International Journal of Cancer 122 558-566.
    • (2008) International Journal of Cancer , vol.122 , pp. 558-566
    • Peng, L.1    Wang, J.2    Malloy, P.J.3    Feldman, D.4
  • 131
    • 61949322951 scopus 로고    scopus 로고
    • The vitamin D receptor agonist elocalcitol inhibits IL-8-dependent benign prostatic hyperplasia stromal cell proliferation and inflammatory response by targeting the RhoA/Rho kinase and NF-kappaB pathways
    • Penna G, Fibbi B, Amuchastegui S, Corsiero E, Laverny G, Silvestrini E, Chavalmane A, Morelli A, Sarchielli E, Vannelli GB et al. 2009 The vitamin D receptor agonist elocalcitol inhibits IL-8-dependent benign prostatic hyperplasia stromal cell proliferation and inflammatory response by targeting the RhoA/Rho kinase and NF-kappaB pathways. Prostate 69 480-493.
    • (2009) Prostate , vol.69 , pp. 480-493
    • Penna, G.1    Fibbi, B.2    Amuchastegui, S.3    Corsiero, E.4    Laverny, G.5    Silvestrini, E.6    Chavalmane, A.7    Morelli, A.8    Sarchielli, E.9    Vannelli, G.B.10
  • 136
    • 40949142209 scopus 로고    scopus 로고
    • The role of hypoxia-inducible factors in tumorigenesis
    • Rankin EB & Giaccia AJ 2008 The role of hypoxia-inducible factors in tumorigenesis. Cell Death and Differentiation 15 678-685.
    • (2008) Cell Death and Differentiation , vol.15 , pp. 678-685
    • Rankin, E.B.1    Giaccia, A.J.2
  • 137
    • 0037027050 scopus 로고    scopus 로고
    • COX-2 selective non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease
    • Ray WA, Stein CM, Daugherty JR, Hall K, Arbogast PG & Griffin MR 2002 COX-2 selective non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease. Lancet 360 1071-1073.
    • (2002) Lancet , vol.360 , pp. 1071-1073
    • Ray, W.A.1    Stein, C.M.2    Daugherty, J.R.3    Hall, K.4    Arbogast, P.G.5    Griffin, M.R.6
  • 138
    • 66449120903 scopus 로고    scopus 로고
    • 3 reduces c-Myc expression, inhibiting proliferation and causing G1 accumulation in C4-2 prostate cancer cells
    • 3 reduces c-Myc expression, inhibiting proliferation and causing G1 accumulation in C4-2 prostate cancer cells. Endocrinology 150 2046-2054.
    • (2009) Endocrinology , vol.150 , pp. 2046-2054
    • Rohan, J.N.1    Weigel, N.L.2
  • 139
    • 33947500486 scopus 로고    scopus 로고
    • Cytokines are a therapeutic target for the prevention of inflammation-induced cancers
    • Rose-John S & Schooltink H 2007 Cytokines are a therapeutic target for the prevention of inflammation-induced cancers. Recent Results in Cancer Research 174 57-66.
    • (2007) Recent Results in Cancer Research , vol.174 , pp. 57-66
    • Rose-John, S.1    Schooltink, H.2
  • 140
    • 39749112953 scopus 로고    scopus 로고
    • Immunohistochemical expression of Ki-67 antigen, Cox-2 and Bax/Bcl-2 in prostate cancer; prognostic value in biopsies and radical prostatectomy specimens
    • Rubio J, Ramos D, Lopez-Guerrero JA, Iborra I, Collado A, Solsona E, Almenar S & Llombart-Bosch A 2005 Immunohistochemical expression of Ki-67 antigen, Cox-2 and Bax/Bcl-2 in prostate cancer; prognostic value in biopsies and radical prostatectomy specimens. European Urology 31 31.
    • (2005) European Urology , vol.31 , pp. 31
    • Rubio, J.1    Ramos, D.2    Lopez-Guerrero, J.A.3    Iborra, I.4    Collado, A.5    Solsona, E.6    Almenar, S.7    Llombart-Bosch, A.8
  • 141
    • 65249138730 scopus 로고    scopus 로고
    • Cyclooxygenase-2 in cancer and angiogenesis
    • Sahin M, Sahin E & Gumuslu S 2009 Cyclooxygenase-2 in cancer and angiogenesis. Angiology 60 242-253.
    • (2009) Angiology , vol.60 , pp. 242-253
    • Sahin, M.1    Sahin, E.2    Gumuslu, S.3
  • 142
    • 39049162107 scopus 로고    scopus 로고
    • Targeting vasculature in urologic tumors: Mechanistic and therapeutic significance
    • Sakamoto S, Ryan AJ & Kyprianou N 2008 Targeting vasculature in urologic tumors: mechanistic and therapeutic significance. Journal of Cellular Biochemistry 103 691-708.
    • (2008) Journal of Cellular Biochemistry , vol.103 , pp. 691-708
    • Sakamoto, S.1    Ryan, A.J.2    Kyprianou, N.3
  • 143
    • 0141643351 scopus 로고    scopus 로고
    • Santilli G, Aronow BJ & Sala A 2003 Essential requirement of apolipoprotein J (clusterin) signaling for IkappaB expression and regulation of NF-kappaB activity. Journal of Biological Chemistry 278 38214-38219.
    • Santilli G, Aronow BJ & Sala A 2003 Essential requirement of apolipoprotein J (clusterin) signaling for IkappaB expression and regulation of NF-kappaB activity. Journal of Biological Chemistry 278 38214-38219.
  • 144
    • 41949104346 scopus 로고    scopus 로고
    • Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: Recommendations of the prostate cancer clinical trials working group
    • Scher HI, Halabi S, Tannock I, Morris M, Sternberg CN, Carducci MA, Eisenberger MA, Higano C, Bubley GJ, Dreicer R et al. 2008 Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the prostate cancer clinical trials working group. Journal of Clinical Oncology 26 1148-1159.
    • (2008) Journal of Clinical Oncology , vol.26 , pp. 1148-1159
    • Scher, H.I.1    Halabi, S.2    Tannock, I.3    Morris, M.4    Sternberg, C.N.5    Carducci, M.A.6    Eisenberger, M.A.7    Higano, C.8    Bubley, G.J.9    Dreicer, R.10
  • 145
    • 0034599429 scopus 로고    scopus 로고
    • Interleukin-6 stimulates clonogenic growth of primary and metastatic human colon carcinoma cells
    • Schneider MR, Hoeflich A, Fischer JR, Wolf E, Sordat B & Lahm H 2000 Interleukin-6 stimulates clonogenic growth of primary and metastatic human colon carcinoma cells. Cancer Letters 151 31-38.
    • (2000) Cancer Letters , vol.151 , pp. 31-38
    • Schneider, M.R.1    Hoeflich, A.2    Fischer, J.R.3    Wolf, E.4    Sordat, B.5    Lahm, H.6
  • 146
    • 34249341731 scopus 로고    scopus 로고
    • Involvement of different nuclear hormone receptors in butyrate-mediated inhibition of inducible NF kappa B signalling
    • Schwab M, Reynders V, Loitsch S, Steinhilber D, Stein J & Schroder O 2007 Involvement of different nuclear hormone receptors in butyrate-mediated inhibition of inducible NF kappa B signalling. Molecular Immunology 44 3625-3632.
    • (2007) Molecular Immunology , vol.44 , pp. 3625-3632
    • Schwab, M.1    Reynders, V.2    Loitsch, S.3    Steinhilber, D.4    Stein, J.5    Schroder, O.6
  • 152
    • 55749084365 scopus 로고    scopus 로고
    • Prostate-specific antigen levels in relation to consumption of nonsteroidal anti-inflammatory drugs and acetaminophen: Results from the 2001-2002 National Health and Nutrition Examination Survey
    • Singer EA, Palapattu GS & van Wijngaarden E 2008 Prostate-specific antigen levels in relation to consumption of nonsteroidal anti-inflammatory drugs and acetaminophen: results from the 2001-2002 National Health and Nutrition Examination Survey. Cancer 113 2053-2057.
    • (2008) Cancer , vol.113 , pp. 2053-2057
    • Singer, E.A.1    Palapattu, G.S.2    van Wijngaarden, E.3
  • 155
    • 55549127613 scopus 로고    scopus 로고
    • Clinical prevention of recurrence of colorectal adenomas by the combination of difluoromethylornithine and sulindac: An important milestone
    • Sporn MB & Hong WK 2008 Clinical prevention of recurrence of colorectal adenomas by the combination of difluoromethylornithine and sulindac: an important milestone. Cancer Prevention Research 1 9-11.
    • (2008) Cancer Prevention Research , vol.1 , pp. 9-11
    • Sporn, M.B.1    Hong, W.K.2
  • 156
    • 68549101673 scopus 로고    scopus 로고
    • A phase II trial of calcitriol and naproxen in recurrent prostate cancer
    • Srinivas S & Feldman D 2009 A phase II trial of calcitriol and naproxen in recurrent prostate cancer. Anticancer Research 29 3605-3610.
    • (2009) Anticancer Research , vol.29 , pp. 3605-3610
    • Srinivas, S.1    Feldman, D.2
  • 160
    • 3242798367 scopus 로고    scopus 로고
    • NF-kappaB activation in human prostate cancer: Important mediator or epiphenomenon?
    • Suh J & Rabson AB 2004 NF-kappaB activation in human prostate cancer: important mediator or epiphenomenon? Journal of Cellular Biochemistry 91 100-117.
    • (2004) Journal of Cellular Biochemistry , vol.91 , pp. 100-117
    • Suh, J.1    Rabson, A.B.2
  • 165
    • 0030890469 scopus 로고    scopus 로고
    • Induction of cyclo-oxygenase-2 mRNA by prostaglandin E2 in human prostatic carcinoma cells
    • Tjandrawinata RR, Dahiya R & Hughes-Fulford M 1997 Induction of cyclo-oxygenase-2 mRNA by prostaglandin E2 in human prostatic carcinoma cells. British Journal of Cancer 75 1111-1118.
    • (1997) British Journal of Cancer , vol.75 , pp. 1111-1118
    • Tjandrawinata, R.R.1    Dahiya, R.2    Hughes-Fulford, M.3
  • 172
    • 4143109119 scopus 로고    scopus 로고
    • Chronic inflammation in benign prostate hyperplasia is associated with focal upregulation of cyclooxygenase-2, Bcl-2, and cell proliferation in the glandular epithelium
    • Wang W, Bergh A & Damber JE 2004 Chronic inflammation in benign prostate hyperplasia is associated with focal upregulation of cyclooxygenase-2, Bcl-2, and cell proliferation in the glandular epithelium. Prostate 61 60-72.
    • (2004) Prostate , vol.61 , pp. 60-72
    • Wang, W.1    Bergh, A.2    Damber, J.E.3
  • 173
    • 18244403761 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression correlates with local chronic inflammation and tumor neovascularization in human prostate cancer
    • Wang W, Bergh A & Damber JE 2005 Cyclooxygenase-2 expression correlates with local chronic inflammation and tumor neovascularization in human prostate cancer. Clinical Cancer Research 11 3250-3256.
    • (2005) Clinical Cancer Research , vol.11 , pp. 3250-3256
    • Wang, W.1    Bergh, A.2    Damber, J.E.3
  • 174
    • 34547655422 scopus 로고    scopus 로고
    • Increased expression of CCAAT/enhancer-binding protein beta in proliferative inflammatory atrophy of the prostate: Relation with the expression of COX-2, the androgen receptor, and presence of focal chronic inflammation
    • Wang W, Bergh A & Damber JE 2007 Increased expression of CCAAT/enhancer-binding protein beta in proliferative inflammatory atrophy of the prostate: relation with the expression of COX-2, the androgen receptor, and presence of focal chronic inflammation. Prostate 67 1238-1246.
    • (2007) Prostate , vol.67 , pp. 1238-1246
    • Wang, W.1    Bergh, A.2    Damber, J.E.3
  • 175
    • 39649113108 scopus 로고    scopus 로고
    • Interleukin-6 activates PI3K/Akt pathway and regulates cyclin A1 to promote prostate cancer cell survival
    • Wegiel B, Bjartell A, Culig Z & Persson JL 2008 Interleukin-6 activates PI3K/Akt pathway and regulates cyclin A1 to promote prostate cancer cell survival. International Journal of Cancer 122 1521-1529.
    • (2008) International Journal of Cancer , vol.122 , pp. 1521-1529
    • Wegiel, B.1    Bjartell, A.2    Culig, Z.3    Persson, J.L.4
  • 176
    • 23744512048 scopus 로고    scopus 로고
    • Prostate specific antigen levels in young adulthood predict prostate cancer risk: Results from a cohort of Black and White Americans
    • Whittemore AS, Cirillo PM, Feldman D & Cohn BA 2005 Prostate specific antigen levels in young adulthood predict prostate cancer risk: results from a cohort of Black and White Americans. Journal of Urology 174 872-876.
    • (2005) Journal of Urology , vol.174 , pp. 872-876
    • Whittemore, A.S.1    Cirillo, P.M.2    Feldman, D.3    Cohn, B.A.4
  • 178
    • 14944379514 scopus 로고    scopus 로고
    • Pilot study: Potential role of vitamin D (cholecalciferol) in patients with PSA relapse after definitive therapy
    • Woo TC, Choo R, Jamieson M, Chander S & Vieth R 2005 Pilot study: potential role of vitamin D (cholecalciferol) in patients with PSA relapse after definitive therapy. Nutrition and Cancer 51 32-36.
    • (2005) Nutrition and Cancer , vol.51 , pp. 32-36
    • Woo, T.C.1    Choo, R.2    Jamieson, M.3    Chander, S.4    Vieth, R.5
  • 179
    • 30744476528 scopus 로고    scopus 로고
    • Involvement of COX-2 in VEGF-induced angiogenesis via P38 and JNK pathways in vascular endothelial cells
    • Wu G, Luo J, Rana JS, Laham R, Sellke FW & Li J 2006 Involvement of COX-2 in VEGF-induced angiogenesis via P38 and JNK pathways in vascular endothelial cells. Cardiovascular Research 69 512-519.
    • (2006) Cardiovascular Research , vol.69 , pp. 512-519
    • Wu, G.1    Luo, J.2    Rana, J.S.3    Laham, R.4    Sellke, F.W.5    Li, J.6
  • 180
    • 34447308768 scopus 로고    scopus 로고
    • Suppression of RelB-mediated manganese superoxide dismutase expression reveals a primary mechanism for radiosensitization effect of 1alpha,25-dihydroxyvitamin D(3) in prostate cancer cells
    • Xu Y, Fang F, St Clair DK, Josson S, Sompol P, Spasojevic I & St Clair WH 2007 Suppression of RelB-mediated manganese superoxide dismutase expression reveals a primary mechanism for radiosensitization effect of 1alpha,25-dihydroxyvitamin D(3) in prostate cancer cells. Molecular Cancer Therapeutics 6 2048-2056.
    • (2007) Molecular Cancer Therapeutics , vol.6 , pp. 2048-2056
    • Xu, Y.1    Fang, F.2    St Clair, D.K.3    Josson, S.4    Sompol, P.5    Spasojevic, I.6    St Clair, W.H.7
  • 181
    • 10644274362 scopus 로고    scopus 로고
    • 15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancers
    • epub 2004 Dec 01
    • Yan M, Rerko RM, Platzer P, Dawson D, Willis J, Tong M, Lawrence E, Lutterbaugh J, Lu S, Willson JK et al. 2004 15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancers. PNAS 101 17468-17473 (epub 2004 Dec 01).
    • (2004) PNAS , vol.101 , pp. 17468-17473
    • Yan, M.1    Rerko, R.M.2    Platzer, P.3    Dawson, D.4    Willis, J.5    Tong, M.6    Lawrence, E.7    Lutterbaugh, J.8    Lu, S.9    Willson, J.K.10
  • 182
    • 0344012519 scopus 로고    scopus 로고
    • Vitamin D inhibits G1 to S progression in LNCaP prostate cancer cells through p27Kip1 stabilization and Cdk2 mislocalization to the cytoplasm
    • Yang ES & Burnstein KL 2003 Vitamin D inhibits G1 to S progression in LNCaP prostate cancer cells through p27Kip1 stabilization and Cdk2 mislocalization to the cytoplasm. Journal of Biological Chemistry 278 46862-46868.
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 46862-46868
    • Yang, E.S.1    Burnstein, K.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.