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Volumn 93, Issue 7, 2015, Pages 735-748

Generation of cardiac progenitor cells through epicardial to mesenchymal transition

Author keywords

Cardiac repair; EMT; Epicardial cells; Molecular rehabilitation

Indexed keywords

BETA CATENIN; CATENIN; CLAUDIN; EPIDERMAL GROWTH FACTOR; FIBRONECTIN; GAP JUNCTION PROTEIN; HYPOXIA INDUCIBLE FACTOR 1; MICRORNA; MICRORNA 141; MICRORNA 200; MICRORNA 29B; MICRORNA 39A; MICRORNA 429; NERVE CELL ADHESION MOLECULE; NOTCH RECEPTOR; PLATELET DERIVED GROWTH FACTOR; PROTEIN TYROSINE KINASE; SCATTER FACTOR; SOMATOMEDIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UVOMORULIN; WNT PROTEIN; ZONULA OCCLUDENS PROTEIN;

EID: 84931570494     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-015-1290-2     Document Type: Review
Times cited : (22)

References (138)
  • 1
    • 84883581618 scopus 로고    scopus 로고
    • Cell therapy for heart failure: a comprehensive overview of experimental and clinical studies, current challenges, and future directions
    • COI: 1:CAS:528:DC%2BC3sXhtlChsL7M, PID: 23989721
    • Sanganalmath SK, Bolli R (2013) Cell therapy for heart failure: a comprehensive overview of experimental and clinical studies, current challenges, and future directions. Circ Res 113:810–834
    • (2013) Circ Res , vol.113 , pp. 810-834
    • Sanganalmath, S.K.1    Bolli, R.2
  • 2
    • 0029553183 scopus 로고
    • An overview of epithelio-mesenchymal transformation
    • COI: 1:STN:280:DyaK283otFSlsA%3D%3D
    • Hay ED (1995) An overview of epithelio-mesenchymal transformation. Acta Anat (Basel) 154:8–20
    • (1995) Acta Anat (Basel) , vol.154 , pp. 8-20
    • Hay, E.D.1
  • 3
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • COI: 1:CAS:528:DC%2BC3cXksFWltA%3D%3D, PID: 19945376
    • Thiery JP, Acloque H, Huang RY, Nieto MA (2009) Epithelial-mesenchymal transitions in development and disease. Cell 139:871–890
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 4
    • 55249126800 scopus 로고    scopus 로고
    • The role of endothelial-to-mesenchymal transition in cancer progression
    • COI: 1:CAS:528:DC%2BD1cXhtlSktb%2FP, PID: 18797460
    • Potenta S, Zeisberg E, Kalluri R (2008) The role of endothelial-to-mesenchymal transition in cancer progression. Br J Cancer 99:1375–1379
    • (2008) Br J Cancer , vol.99 , pp. 1375-1379
    • Potenta, S.1    Zeisberg, E.2    Kalluri, R.3
  • 5
    • 34548145815 scopus 로고    scopus 로고
    • Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition
    • COI: 1:CAS:528:DC%2BD2sXosVyrsb8%3D, PID: 17562716
    • Zeisberg M, Yang C, Martino M, Duncan MB, Rieder F, Tanjore H, Kalluri R (2007) Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition. J Biol Chem 282:23337–23347
    • (2007) J Biol Chem , vol.282 , pp. 23337-23347
    • Zeisberg, M.1    Yang, C.2    Martino, M.3    Duncan, M.B.4    Rieder, F.5    Tanjore, H.6    Kalluri, R.7
  • 6
    • 33748375828 scopus 로고    scopus 로고
    • Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix
    • COI: 1:CAS:528:DC%2BD28Xptlels74%3D, PID: 16924102
    • Kim KK, Kugler MC, Wolters PJ, Robillard L, Galvez MG, Brumwell AN, Sheppard D, Chapman HA (2006) Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix. Proc Natl Acad Sci U S A 103:13180–13185
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 13180-13185
    • Kim, K.K.1    Kugler, M.C.2    Wolters, P.J.3    Robillard, L.4    Galvez, M.G.5    Brumwell, A.N.6    Sheppard, D.7    Chapman, H.A.8
  • 7
    • 84885915873 scopus 로고    scopus 로고
    • Epithelial-mesenchymal plasticity in carcinoma metastasis
    • COI: 1:CAS:528:DC%2BC3sXhslCjt7zO, PID: 24142872
    • Tsai JH, Yang J (2013) Epithelial-mesenchymal plasticity in carcinoma metastasis. Genes Dev 27:2192–2206
    • (2013) Genes Dev , vol.27 , pp. 2192-2206
    • Tsai, J.H.1    Yang, J.2
  • 8
    • 2442705493 scopus 로고    scopus 로고
    • Snail blocks the cell cycle and confers resistance to cell death
    • COI: 1:CAS:528:DC%2BD2cXktlCqs74%3D, PID: 15155580
    • Vega S, Morales AV, Ocana OH, Valdes F, Fabregat I, Nieto MA (2004) Snail blocks the cell cycle and confers resistance to cell death. Genes Dev 18:1131–1143
    • (2004) Genes Dev , vol.18 , pp. 1131-1143
    • Vega, S.1    Morales, A.V.2    Ocana, O.H.3    Valdes, F.4    Fabregat, I.5    Nieto, M.A.6
  • 10
    • 84906770124 scopus 로고    scopus 로고
    • The function and regulation of mesenchymal-to-epithelial transition in somatic cell reprogramming
    • Shu X, Pei D (2014) The function and regulation of mesenchymal-to-epithelial transition in somatic cell reprogramming. Curr Opin Genet Dev 28C:32–37
    • (2014) Curr Opin Genet Dev , vol.28C , pp. 32-37
    • Shu, X.1    Pei, D.2
  • 11
    • 41549162752 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states in development and disease
    • COI: 1:CAS:528:DC%2BD1cXksVaqt7g%3D, PID: 18343170
    • Baum B, Settleman J, Quinlan MP (2008) Transitions between epithelial and mesenchymal states in development and disease. Semin Cell Dev Biol 19:294–308
    • (2008) Semin Cell Dev Biol , vol.19 , pp. 294-308
    • Baum, B.1    Settleman, J.2    Quinlan, M.P.3
  • 12
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • COI: 1:CAS:528:DC%2BD1MXntVCjtr0%3D, PID: 19487818
    • Kalluri R, Weinberg RA (2009) The basics of epithelial-mesenchymal transition. J Clin Invest 119:1420–1428
    • (2009) J Clin Invest , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 13
    • 84894593599 scopus 로고    scopus 로고
    • Molecular mechanisms of epithelial-mesenchymal transition
    • COI: 1:CAS:528:DC%2BC2cXivFagtrY%3D, PID: 24556840
    • Lamouille S, Xu J, Derynck R (2014) Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol 15:178–196
    • (2014) Nat Rev Mol Cell Biol , vol.15 , pp. 178-196
    • Lamouille, S.1    Xu, J.2    Derynck, R.3
  • 14
  • 15
  • 16
    • 34548411746 scopus 로고    scopus 로고
    • TGF-beta-induced EMT: mechanisms and implications for fibrotic lung disease
    • COI: 1:CAS:528:DC%2BD2sXhtVOqsbjP, PID: 17631612
    • Willis BC, Borok Z (2007) TGF-beta-induced EMT: mechanisms and implications for fibrotic lung disease. Am J Physiol Lung Cell Mol Physiol 293:L525–L534
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.293 , pp. L525-L534
    • Willis, B.C.1    Borok, Z.2
  • 19
    • 58549116088 scopus 로고    scopus 로고
    • Slug/Snai2 is a downstream mediator of epidermal growth factor receptor-stimulated reepithelialization
    • COI: 1:CAS:528:DC%2BD1MXmt1GksA%3D%3D, PID: 18685621
    • Kusewitt DF, Choi C, Newkirk KM, Leroy P, Li Y, Chavez MG, Hudson LG (2009) Slug/Snai2 is a downstream mediator of epidermal growth factor receptor-stimulated reepithelialization. J Investig Dermatol 129:491–495
    • (2009) J Investig Dermatol , vol.129 , pp. 491-495
    • Kusewitt, D.F.1    Choi, C.2    Newkirk, K.M.3    Leroy, P.4    Li, Y.5    Chavez, M.G.6    Hudson, L.G.7
  • 20
    • 79959628679 scopus 로고    scopus 로고
    • Experimental myocardial infarction triggers canonical Wnt signaling and endothelial-to-mesenchymal transition
    • COI: 1:CAS:528:DC%2BC3MXptFWgtrc%3D, PID: 21324930
    • Aisagbonhi O, Rai M, Ryzhov S, Atria N, Feoktistov I, Hatzopoulos AK (2011) Experimental myocardial infarction triggers canonical Wnt signaling and endothelial-to-mesenchymal transition. Dis Model Mech 4:469–483
    • (2011) Dis Model Mech , vol.4 , pp. 469-483
    • Aisagbonhi, O.1    Rai, M.2    Ryzhov, S.3    Atria, N.4    Feoktistov, I.5    Hatzopoulos, A.K.6
  • 21
    • 48749122568 scopus 로고    scopus 로고
    • Keratinocyte-specific Smad2 ablation results in increased epithelial-mesenchymal transition during skin cancer formation and progression
    • COI: 1:CAS:528:DC%2BD1cXpsVOktLg%3D, PID: 18618014
    • Hoot KE, Lighthall J, Han G, Lu SL, Li A, Ju W, Kulesz-Martin M, Bottinger E, Wang XJ (2008) Keratinocyte-specific Smad2 ablation results in increased epithelial-mesenchymal transition during skin cancer formation and progression. J Clin Invest 118:2722–2732
    • (2008) J Clin Invest , vol.118 , pp. 2722-2732
    • Hoot, K.E.1    Lighthall, J.2    Han, G.3    Lu, S.L.4    Li, A.5    Ju, W.6    Kulesz-Martin, M.7    Bottinger, E.8    Wang, X.J.9
  • 22
    • 84908326985 scopus 로고    scopus 로고
    • Breast cancer stem cells, EMT and therapeutic targets
    • COI: 1:CAS:528:DC%2BC2cXhs1Gnu7bF, PID: 25261721
    • Kotiyal S, Bhattacharya S (2014) Breast cancer stem cells, EMT and therapeutic targets. Biochem Biophys Res Commun 453:112–116
    • (2014) Biochem Biophys Res Commun , vol.453 , pp. 112-116
    • Kotiyal, S.1    Bhattacharya, S.2
  • 23
    • 51449085561 scopus 로고    scopus 로고
    • Generation of breast cancer stem cells through epithelial-mesenchymal transition
    • PID: 18682804
    • Morel AP, Lievre M, Thomas C, Hinkal G, Ansieau S, Puisieux A (2008) Generation of breast cancer stem cells through epithelial-mesenchymal transition. PLoS One 3, e2888
    • (2008) PLoS One , vol.3
    • Morel, A.P.1    Lievre, M.2    Thomas, C.3    Hinkal, G.4    Ansieau, S.5    Puisieux, A.6
  • 24
    • 79951797048 scopus 로고    scopus 로고
    • The transforming growth factor-beta (TGF-beta) mediates acquisition of a mesenchymal stem cell-like phenotype in human liver cells
    • COI: 1:CAS:528:DC%2BC3MXit1ehtLg%3D, PID: 20945437
    • Caja L, Bertran E, Campbell J, Fausto N, Fabregat I (2011) The transforming growth factor-beta (TGF-beta) mediates acquisition of a mesenchymal stem cell-like phenotype in human liver cells. J Cell Physiol 226:1214–1223
    • (2011) J Cell Physiol , vol.226 , pp. 1214-1223
    • Caja, L.1    Bertran, E.2    Campbell, J.3    Fausto, N.4    Fabregat, I.5
  • 25
    • 84907501988 scopus 로고    scopus 로고
    • Signaling mechanisms of the epithelial-mesenchymal transition
    • PID: 25249658
    • Gonzalez DM, Medici D (2014) Signaling mechanisms of the epithelial-mesenchymal transition. Sci Signal 7:re8
    • (2014) Sci Signal , vol.7 , pp. re8
    • Gonzalez, D.M.1    Medici, D.2
  • 26
    • 34547699399 scopus 로고    scopus 로고
    • Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury
    • COI: 1:CAS:528:DC%2BD2sXos1Cjsbk%3D, PID: 17660827
    • Hsieh PC, Segers VF, Davis ME, MacGillivray C, Gannon J, Molkentin JD, Robbins J, Lee RT (2007) Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury. Nat Med 13:970–974
    • (2007) Nat Med , vol.13 , pp. 970-974
    • Hsieh, P.C.1    Segers, V.F.2    Davis, M.E.3    MacGillivray, C.4    Gannon, J.5    Molkentin, J.D.6    Robbins, J.7    Lee, R.T.8
  • 29
    • 84878850858 scopus 로고    scopus 로고
    • Cardiac stem cell therapy and the promise of heart regeneration
    • COI: 1:CAS:528:DC%2BC3sXptFOlt7Y%3D, PID: 23746978
    • Garbern JC, Lee RT (2013) Cardiac stem cell therapy and the promise of heart regeneration. Cell Stem Cell 12:689–698
    • (2013) Cell Stem Cell , vol.12 , pp. 689-698
    • Garbern, J.C.1    Lee, R.T.2
  • 30
    • 84911381525 scopus 로고    scopus 로고
    • A neonatal blueprint for cardiac regeneration
    • Porrello ER, Olson EN (2014) A neonatal blueprint for cardiac regeneration. Stem Cell Res 13(3 Pt B):556–570
    • (2014) Stem Cell Res , vol.13 , pp. 556-570
    • Porrello, E.R.1    Olson, E.N.2
  • 31
    • 84911371541 scopus 로고    scopus 로고
    • Cardiac regeneration in vivo: mending the heart from within?
    • Bergmann O, Jovinge S (2014) Cardiac regeneration in vivo: mending the heart from within? Stem Cell Res 13(3 Pt B):523–531
    • (2014) Stem Cell Res , vol.13 , pp. 523-531
    • Bergmann, O.1    Jovinge, S.2
  • 33
    • 84898406320 scopus 로고    scopus 로고
    • Do neonatal mouse hearts regenerate following heart apex resection?
    • COI: 1:CAS:528:DC%2BC2cXhtFWisLnJ
    • Andersen DC, Ganesalingam S, Jensen CH, Sheikh SP (2014) Do neonatal mouse hearts regenerate following heart apex resection? Stem Cell Rep 2:406–413
    • (2014) Stem Cell Rep , vol.2 , pp. 406-413
    • Andersen, D.C.1    Ganesalingam, S.2    Jensen, C.H.3    Sheikh, S.P.4
  • 35
    • 84904176540 scopus 로고    scopus 로고
    • Multi-investigator letter on reproducibility of neonatal heart regeneration following apical resection
    • Sadek HA, Martin JF, Takeuchi JK, Leor J, Nei Y, Giacca M, Lee RT (2014) Multi-investigator letter on reproducibility of neonatal heart regeneration following apical resection. Stem Cell Rep 3:1
    • (2014) Stem Cell Rep , vol.3 , pp. 1
    • Sadek, H.A.1    Martin, J.F.2    Takeuchi, J.K.3    Leor, J.4    Nei, Y.5    Giacca, M.6    Lee, R.T.7
  • 36
    • 84902602979 scopus 로고    scopus 로고
    • Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice
    • COI: 1:CAS:528:DC%2BC2cXovVejs7Y%3D, PID: 24876275
    • Ali SR, Hippenmeyer S, Saadat LV, Luo L, Weissman IL, Ardehali R (2014) Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice. Proc Natl Acad Sci U S A 111:8850–8855
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 8850-8855
    • Ali, S.R.1    Hippenmeyer, S.2    Saadat, L.V.3    Luo, L.4    Weissman, I.L.5    Ardehali, R.6
  • 38
    • 21144458217 scopus 로고    scopus 로고
    • Stem cells in the dog heart are self-renewing, clonogenic, and multipotent and regenerate infarcted myocardium, improving cardiac function
    • COI: 1:CAS:528:DC%2BD2MXlvF2qu7c%3D, PID: 15951423
    • Linke A, Muller P, Nurzynska D, Casarsa C, Torella D, Nascimbene A, Castaldo C, Cascapera S, Bohm M, Quaini F et al (2005) Stem cells in the dog heart are self-renewing, clonogenic, and multipotent and regenerate infarcted myocardium, improving cardiac function. Proc Natl Acad Sci U S A 102:8966–8971
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 8966-8971
    • Linke, A.1    Muller, P.2    Nurzynska, D.3    Casarsa, C.4    Torella, D.5    Nascimbene, A.6    Castaldo, C.7    Cascapera, S.8    Bohm, M.9    Quaini, F.10
  • 40
    • 84911360518 scopus 로고    scopus 로고
    • Developmental origins and lineage descendants of endogenous adult cardiac progenitor cells
    • COI: 1:CAS:528:DC%2BC2cXhslags73N, PID: 25459343
    • Chong JJ, Forte E, Harvey RP (2014) Developmental origins and lineage descendants of endogenous adult cardiac progenitor cells. Stem Cell Res 13:592–614
    • (2014) Stem Cell Res , vol.13 , pp. 592-614
    • Chong, J.J.1    Forte, E.2    Harvey, R.P.3
  • 41
    • 84923535492 scopus 로고    scopus 로고
    • An emerging consensus on cardiac regeneration
    • PID: 25473919
    • van Berlo JH, Molkentin JD (2014) An emerging consensus on cardiac regeneration. Nat Med 20:1386–1393
    • (2014) Nat Med , vol.20 , pp. 1386-1393
    • van Berlo, J.H.1    Molkentin, J.D.2
  • 45
    • 77952241680 scopus 로고    scopus 로고
    • Cardiomyogenic potential of c-kit(+)-expressing cells derived from neonatal and adult mouse hearts
    • COI: 1:CAS:528:DC%2BC3cXlvVakur8%3D, PID: 20421520
    • Zaruba MM, Soonpaa M, Reuter S, Field LJ (2010) Cardiomyogenic potential of c-kit(+)-expressing cells derived from neonatal and adult mouse hearts. Circulation 121:1992–2000
    • (2010) Circulation , vol.121 , pp. 1992-2000
    • Zaruba, M.M.1    Soonpaa, M.2    Reuter, S.3    Field, L.J.4
  • 47
    • 84860390421 scopus 로고    scopus 로고
    • Endogenous cardiac stem cell activation by insulin-like growth factor-1/hepatocyte growth factor intracoronary injection fosters survival and regeneration of the infarcted pig heart
    • COI: 1:CAS:528:DC%2BC3MXht1Srt7%2FF, PID: 21723061
    • Ellison GM, Torella D, Dellegrottaglie S, Perez-Martinez C, Perez de Prado A, Vicinanza C, Purushothaman S, Galuppo V, Iaconetti C, Waring CD et al (2011) Endogenous cardiac stem cell activation by insulin-like growth factor-1/hepatocyte growth factor intracoronary injection fosters survival and regeneration of the infarcted pig heart. J Am Coll Cardiol 58:977–986
    • (2011) J Am Coll Cardiol , vol.58 , pp. 977-986
    • Ellison, G.M.1    Torella, D.2    Dellegrottaglie, S.3    Perez-Martinez, C.4    Perez de Prado, A.5    Vicinanza, C.6    Purushothaman, S.7    Galuppo, V.8    Iaconetti, C.9    Waring, C.D.10
  • 48
    • 84869992760 scopus 로고    scopus 로고
    • Stem cell factor gene transfer promotes cardiac repair after myocardial infarction via in situ recruitment and expansion of c-kit+ cells
    • COI: 1:CAS:528:DC%2BC38Xhs1eit7nF, PID: 22931954
    • Yaniz-Galende E, Chen J, Chemaly E, Liang L, Hulot JS, McCollum L, Arias T, Fuster V, Zsebo KM, Hajjar RJ (2012) Stem cell factor gene transfer promotes cardiac repair after myocardial infarction via in situ recruitment and expansion of c-kit+ cells. Circ Res 111:1434–1445
    • (2012) Circ Res , vol.111 , pp. 1434-1445
    • Yaniz-Galende, E.1    Chen, J.2    Chemaly, E.3    Liang, L.4    Hulot, J.S.5    McCollum, L.6    Arias, T.7    Fuster, V.8    Zsebo, K.M.9    Hajjar, R.J.10
  • 49
    • 84873961120 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase-induced myocardial repair is mediated by c-kit in infarcted hearts
    • COI: 1:CAS:528:DC%2BC38Xhs12ksL%2FP, PID: 23024362
    • Zhang L, Chen B, Zhao Y, Dubielecka PM, Wei L, Qin GJ, Chin YE, Wang Y, Zhao TC (2012) Inhibition of histone deacetylase-induced myocardial repair is mediated by c-kit in infarcted hearts. J Biol Chem 287:39338–39348
    • (2012) J Biol Chem , vol.287 , pp. 39338-39348
    • Zhang, L.1    Chen, B.2    Zhao, Y.3    Dubielecka, P.M.4    Wei, L.5    Qin, G.J.6    Chin, Y.E.7    Wang, Y.8    Zhao, T.C.9
  • 52
    • 84885988436 scopus 로고    scopus 로고
    • Are resident c-Kit+ cardiac stem cells really all that are needed to mend a broken heart?
    • COI: 1:CAS:528:DC%2BC3sXhsFyktrbP, PID: 24115067
    • Molkentin JD, Houser SR (2013) Are resident c-Kit+ cardiac stem cells really all that are needed to mend a broken heart? Circ Res 113:1037–1039
    • (2013) Circ Res , vol.113 , pp. 1037-1039
    • Molkentin, J.D.1    Houser, S.R.2
  • 53
    • 84894438118 scopus 로고    scopus 로고
    • Adult c-kit(pos) cardiac stem cells fulfill Koch’s postulates as causal agents for cardiac regeneration
    • COI: 1:CAS:528:DC%2BC2cXisVCgsbk%3D, PID: 24526679
    • Torella D, Ellison GM, Nadal-Ginard B (2014) Adult c-kit(pos) cardiac stem cells fulfill Koch’s postulates as causal agents for cardiac regeneration. Circ Res 114:e24–e26
    • (2014) Circ Res , vol.114 , pp. e24-e26
    • Torella, D.1    Ellison, G.M.2    Nadal-Ginard, B.3
  • 54
    • 84894411150 scopus 로고    scopus 로고
    • Response to Torella et al
    • COI: 1:CAS:528:DC%2BC2cXisVCgsbc%3D, PID: 24526680
    • Molkentin JD, Houser SR (2014) Response to Torella et al. Circ Res 114, e27
    • (2014) Circ Res , vol.114
    • Molkentin, J.D.1    Houser, S.R.2
  • 55
    • 84905220260 scopus 로고    scopus 로고
    • Absence of evidence is not evidence of absence: pitfalls of Cre Knock-Ins in the c-Kit locus
    • COI: 1:CAS:528:DC%2BC2cXht1Ckt7fE, PID: 24965482
    • Nadal-Ginard B, Ellison GM, Torella D (2014) Absence of evidence is not evidence of absence: pitfalls of Cre Knock-Ins in the c-Kit locus. Circ Res 115:415–418
    • (2014) Circ Res , vol.115 , pp. 415-418
    • Nadal-Ginard, B.1    Ellison, G.M.2    Torella, D.3
  • 56
    • 84917744032 scopus 로고    scopus 로고
    • Letter by Molkentin regarding article, “the absence of evidence is not evidence of absence: the pitfalls of Cre Knock-Ins in the c-Kit locus
    • COI: 1:CAS:528:DC%2BC2cXhs1SisrnL, PID: 25258403
    • Molkentin JD (2014) Letter by Molkentin regarding article, “the absence of evidence is not evidence of absence: the pitfalls of Cre Knock-Ins in the c-Kit locus”. Circ Res 115:e21–e23
    • (2014) Circ Res , vol.115 , pp. e21-e23
    • Molkentin, J.D.1
  • 57
    • 84917730282 scopus 로고    scopus 로고
    • Response to Molkentin’s letter to the editor regarding article, “the absence of evidence is not evidence of absence: the pitfalls of Cre Knock-Ins in the c-Kit locus
    • COI: 1:CAS:528:DC%2BC2cXitVamtbzK, PID: 25477488
    • Nadal-Ginard B, Ellison GM, Torella D (2014) Response to Molkentin’s letter to the editor regarding article, “the absence of evidence is not evidence of absence: the pitfalls of Cre Knock-Ins in the c-Kit locus”. Circ Res 115:e38–e39
    • (2014) Circ Res , vol.115 , pp. e38-e39
    • Nadal-Ginard, B.1    Ellison, G.M.2    Torella, D.3
  • 61
    • 55049116647 scopus 로고    scopus 로고
    • CD117-positive cells in adult human heart are localized in the subepicardium, and their activation is associated with laminin-1 and alpha6 integrin expression
    • COI: 1:CAS:528:DC%2BD1cXpvV2mu74%3D, PID: 18436868
    • Castaldo C, Di Meglio F, Nurzynska D, Romano G, Maiello C, Bancone C, Muller P, Bohm M, Cotrufo M, Montagnani S (2008) CD117-positive cells in adult human heart are localized in the subepicardium, and their activation is associated with laminin-1 and alpha6 integrin expression. Stem Cells 26:1723–1731
    • (2008) Stem Cells , vol.26 , pp. 1723-1731
    • Castaldo, C.1    Di Meglio, F.2    Nurzynska, D.3    Romano, G.4    Maiello, C.5    Bancone, C.6    Muller, P.7    Bohm, M.8    Cotrufo, M.9    Montagnani, S.10
  • 65
    • 33847084614 scopus 로고    scopus 로고
    • Formation and function of the myofibroblast during tissue repair
    • COI: 1:CAS:528:DC%2BD2sXhs1Crt7o%3D, PID: 17299435
    • Hinz B (2007) Formation and function of the myofibroblast during tissue repair. J Investig Dermatol 127:526–537
    • (2007) J Investig Dermatol , vol.127 , pp. 526-537
    • Hinz, B.1
  • 66
    • 34447116292 scopus 로고    scopus 로고
    • Cardiovascular development and the colonizing cardiac neural crest lineage
    • COI: 1:CAS:528:DC%2BD2sXhtlequ73M, PID: 17619792
    • Snider P, Olaopa M, Firulli AB, Conway SJ (2007) Cardiovascular development and the colonizing cardiac neural crest lineage. ScientificWorldJournal 7:1090–1113
    • (2007) ScientificWorldJournal , vol.7 , pp. 1090-1113
    • Snider, P.1    Olaopa, M.2    Firulli, A.B.3    Conway, S.J.4
  • 67
    • 79959944022 scopus 로고    scopus 로고
    • Target cell movement in tumor and cardiovascular diseases based on the epithelial-mesenchymal transition concept
    • COI: 1:CAS:528:DC%2BC3MXoslaltbY%3D, PID: 21335038
    • Chua KN, Poon KL, Lim J, Sim WJ, Huang RY, Thiery JP (2011) Target cell movement in tumor and cardiovascular diseases based on the epithelial-mesenchymal transition concept. Adv Drug Deliv Rev 63:558–567
    • (2011) Adv Drug Deliv Rev , vol.63 , pp. 558-567
    • Chua, K.N.1    Poon, K.L.2    Lim, J.3    Sim, W.J.4    Huang, R.Y.5    Thiery, J.P.6
  • 68
    • 42349086538 scopus 로고    scopus 로고
    • Embryonic development of the proepicardium and coronary vessels
    • PID: 18311713
    • Ratajska A, Czarnowska E, Ciszek B (2008) Embryonic development of the proepicardium and coronary vessels. Int J Dev Biol 52:229–236
    • (2008) Int J Dev Biol , vol.52 , pp. 229-236
    • Ratajska, A.1    Czarnowska, E.2    Ciszek, B.3
  • 69
    • 0034956857 scopus 로고    scopus 로고
    • The origin, formation and developmental significance of the epicardium: a review
    • COI: 1:STN:280:DC%2BD3MzjtFGktg%3D%3D, PID: 11399849
    • Manner J, Perez-Pomares JM, Macias D, Munoz-Chapuli R (2001) The origin, formation and developmental significance of the epicardium: a review. Cells Tissues Organs 169:89–103
    • (2001) Cells Tissues Organs , vol.169 , pp. 89-103
    • Manner, J.1    Perez-Pomares, J.M.2    Macias, D.3    Munoz-Chapuli, R.4
  • 70
    • 84856115740 scopus 로고    scopus 로고
    • Signaling during epicardium and coronary vessel development
    • COI: 1:CAS:528:DC%2BC3MXhsF2jsrvO, PID: 22158650
    • Perez-Pomares JM, de la Pompa JL (2011) Signaling during epicardium and coronary vessel development. Circ Res 109:1429–1442
    • (2011) Circ Res , vol.109 , pp. 1429-1442
    • Perez-Pomares, J.M.1    de la Pompa, J.L.2
  • 71
    • 0036842333 scopus 로고    scopus 로고
    • Development of the coronary vessel system
    • COI: 1:CAS:528:DC%2BD38XotFKjsrw%3D, PID: 12411389
    • Reese DE, Mikawa T, Bader DM (2002) Development of the coronary vessel system. Circ Res 91:761–768
    • (2002) Circ Res , vol.91 , pp. 761-768
    • Reese, D.E.1    Mikawa, T.2    Bader, D.M.3
  • 72
    • 0346690330 scopus 로고    scopus 로고
    • The epicardium and epicardially derived cells (EPDCs) as cardiac stem cells
    • COI: 1:STN:280:DC%2BD2c%2FgtF2jsA%3D%3D
    • Wessels A, Perez-Pomares JM (2004) The epicardium and epicardially derived cells (EPDCs) as cardiac stem cells. Anat Rec A: Discov Mol Cell Evol Biol 276:43–57
    • (2004) Anat Rec A: Discov Mol Cell Evol Biol , vol.276 , pp. 43-57
    • Wessels, A.1    Perez-Pomares, J.M.2
  • 76
    • 79958799319 scopus 로고    scopus 로고
    • Epicardial-derived cell epithelial-to-mesenchymal transition and fate specification require PDGF receptor signaling
    • COI: 1:CAS:528:DC%2BC3MXntF2htrc%3D, PID: 21512159
    • Smith CL, Baek ST, Sung CY, Tallquist MD (2011) Epicardial-derived cell epithelial-to-mesenchymal transition and fate specification require PDGF receptor signaling. Circ Res 108:e15–e26
    • (2011) Circ Res , vol.108 , pp. e15-e26
    • Smith, C.L.1    Baek, S.T.2    Sung, C.Y.3    Tallquist, M.D.4
  • 77
    • 29644432271 scopus 로고    scopus 로고
    • The serosal mesothelium is a major source of smooth muscle cells of the gut vasculature
    • COI: 1:CAS:528:DC%2BD28Xktlehuw%3D%3D, PID: 16284122
    • Wilm B, Ipenberg A, Hastie ND, Burch JB, Bader DM (2005) The serosal mesothelium is a major source of smooth muscle cells of the gut vasculature. Development 132:5317–5328
    • (2005) Development , vol.132 , pp. 5317-5328
    • Wilm, B.1    Ipenberg, A.2    Hastie, N.D.3    Burch, J.B.4    Bader, D.M.5
  • 78
    • 84927169682 scopus 로고    scopus 로고
    • Cellular origin and developmental program of coronary angiogenesis
    • COI: 1:CAS:528:DC%2BC2MXhs12ktL4%3D, PID: 25634974
    • Tian X, Pu WT, Zhou B (2015) Cellular origin and developmental program of coronary angiogenesis. Circ Res 116:515–530
    • (2015) Circ Res , vol.116 , pp. 515-530
    • Tian, X.1    Pu, W.T.2    Zhou, B.3
  • 79
    • 77950237662 scopus 로고    scopus 로고
    • Coronary arteries form by developmental reprogramming of venous cells
    • COI: 1:CAS:528:DC%2BC3cXjvVGlur4%3D, PID: 20336138
    • Red-Horse K, Ueno H, Weissman IL, Krasnow MA (2010) Coronary arteries form by developmental reprogramming of venous cells. Nature 464:549–553
    • (2010) Nature , vol.464 , pp. 549-553
    • Red-Horse, K.1    Ueno, H.2    Weissman, I.L.3    Krasnow, M.A.4
  • 81
    • 0027227849 scopus 로고
    • Development of the cardiac coronary vascular endothelium, studied with antiendothelial antibodies, in chicken-quail chimeras
    • COI: 1:STN:280:DyaK3szltFehtg%3D%3D, PID: 8348697
    • Poelmann RE, Gittenberger-de Groot AC, Mentink MM, Bokenkamp R, Hogers B (1993) Development of the cardiac coronary vascular endothelium, studied with antiendothelial antibodies, in chicken-quail chimeras. Circ Res 73:559–568
    • (1993) Circ Res , vol.73 , pp. 559-568
    • Poelmann, R.E.1    Gittenberger-de Groot, A.C.2    Mentink, M.M.3    Bokenkamp, R.4    Hogers, B.5
  • 82
    • 84883318758 scopus 로고    scopus 로고
    • Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries
    • COI: 1:CAS:528:DC%2BC3sXhsVWqsrvO, PID: 23797856
    • Tian X, Hu T, Zhang H, He L, Huang X, Liu Q, Yu W, He L, Yang Z, Zhang Z et al (2013) Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries. Cell Res 23:1075–1090
    • (2013) Cell Res , vol.23 , pp. 1075-1090
    • Tian, X.1    Hu, T.2    Zhang, H.3    He, L.4    Huang, X.5    Liu, Q.6    Yu, W.7    He, L.8    Yang, Z.9    Zhang, Z.10
  • 83
    • 84903703870 scopus 로고    scopus 로고
    • Vessel formation. De novo formation of a distinct coronary vascular population in neonatal heart
    • COI: 1:CAS:528:DC%2BC2cXhtVKlu7bP, PID: 24994653
    • Tian X, Hu T, Zhang H, He L, Huang X, Liu Q, Yu W, He L, Yang Z, Yan Y et al (2014) Vessel formation. De novo formation of a distinct coronary vascular population in neonatal heart. Science 345:90–94
    • (2014) Science , vol.345 , pp. 90-94
    • Tian, X.1    Hu, T.2    Zhang, H.3    He, L.4    Huang, X.5    Liu, Q.6    Yu, W.7    He, L.8    Yang, Z.9    Yan, Y.10
  • 87
    • 84863655597 scopus 로고    scopus 로고
    • Wt1 and epicardial fate mapping
    • COI: 1:CAS:528:DC%2BC38XpvVejsL4%3D, PID: 22693350
    • Rudat C, Kispert A (2012) Wt1 and epicardial fate mapping. Circ Res 111:165–169
    • (2012) Circ Res , vol.111 , pp. 165-169
    • Rudat, C.1    Kispert, A.2
  • 90
    • 84866510102 scopus 로고    scopus 로고
    • Heart repair and regeneration: recent insights from zebrafish studies
    • PID: 22818295
    • Lien CL, Harrison MR, Tuan TL, Starnes VA (2012) Heart repair and regeneration: recent insights from zebrafish studies. Wound Repair Regen 20:638–646
    • (2012) Wound Repair Regen , vol.20 , pp. 638-646
    • Lien, C.L.1    Harrison, M.R.2    Tuan, T.L.3    Starnes, V.A.4
  • 91
    • 33750483609 scopus 로고    scopus 로고
    • A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration
    • COI: 1:CAS:528:DC%2BD28Xht1Wgtb%2FK, PID: 17081981
    • Lepilina A, Coon AN, Kikuchi K, Holdway JE, Roberts RW, Burns CG, Poss KD (2006) A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration. Cell 127:607–619
    • (2006) Cell , vol.127 , pp. 607-619
    • Lepilina, A.1    Coon, A.N.2    Kikuchi, K.3    Holdway, J.E.4    Roberts, R.W.5    Burns, C.G.6    Poss, K.D.7
  • 92
    • 79952527330 scopus 로고    scopus 로고
    • Retinoic acid production by endocardium and epicardium is an injury response essential for zebrafish heart regeneration
    • COI: 1:CAS:528:DC%2BC3MXjtFeqtLs%3D, PID: 21397850
    • Kikuchi K, Holdway JE, Major RJ, Blum N, Dahn RD, Begemann G, Poss KD (2011) Retinoic acid production by endocardium and epicardium is an injury response essential for zebrafish heart regeneration. Dev Cell 20:397–404
    • (2011) Dev Cell , vol.20 , pp. 397-404
    • Kikuchi, K.1    Holdway, J.E.2    Major, R.J.3    Blum, N.4    Dahn, R.D.5    Begemann, G.6    Poss, K.D.7
  • 93
    • 78049235110 scopus 로고    scopus 로고
    • PDGF signaling is required for epicardial function and blood vessel formation in regenerating zebrafish hearts
    • COI: 1:CAS:528:DC%2BC3cXhtlSjurrE, PID: 20858732
    • Kim J, Wu Q, Zhang Y, Wiens KM, Huang Y, Rubin N, Shimada H, Handin RI, Chao MY, Tuan TL et al (2010) PDGF signaling is required for epicardial function and blood vessel formation in regenerating zebrafish hearts. Proc Natl Acad Sci U S A 107:17206–17210
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 17206-17210
    • Kim, J.1    Wu, Q.2    Zhang, Y.3    Wiens, K.M.4    Huang, Y.5    Rubin, N.6    Shimada, H.7    Handin, R.I.8    Chao, M.Y.9    Tuan, T.L.10
  • 94
    • 79959427955 scopus 로고    scopus 로고
    • Tcf21+ epicardial cells adopt non-myocardial fates during zebrafish heart development and regeneration
    • COI: 1:CAS:528:DC%2BC3MXhtVyjsrjE, PID: 21653610
    • Kikuchi K, Gupta V, Wang J, Holdway JE, Wills AA, Fang Y, Poss KD (2011) Tcf21+ epicardial cells adopt non-myocardial fates during zebrafish heart development and regeneration. Development 138:2895–2902
    • (2011) Development , vol.138 , pp. 2895-2902
    • Kikuchi, K.1    Gupta, V.2    Wang, J.3    Holdway, J.E.4    Wills, A.A.5    Fang, Y.6    Poss, K.D.7
  • 95
    • 84055214880 scopus 로고    scopus 로고
    • Thymosin beta 4 treatment after myocardial infarction does not reprogram epicardial cells into cardiomyocytes
    • COI: 1:CAS:528:DC%2BC3MXhs1Omu73O, PID: 21907210
    • Zhou B, Honor LB, Ma Q, Oh JH, Lin RZ, Melero-Martin JM, von Gise A, Zhou P, Hu T, He L et al (2012) Thymosin beta 4 treatment after myocardial infarction does not reprogram epicardial cells into cardiomyocytes. J Mol Cell Cardiol 52:43–47
    • (2012) J Mol Cell Cardiol , vol.52 , pp. 43-47
    • Zhou, B.1    Honor, L.B.2    Ma, Q.3    Oh, J.H.4    Lin, R.Z.5    Melero-Martin, J.M.6    von Gise, A.7    Zhou, P.8    Hu, T.9    He, L.10
  • 96
    • 84904640712 scopus 로고    scopus 로고
    • Re-activated adult epicardial progenitor cells are a heterogeneous population molecularly distinct from their embryonic counterparts
    • COI: 1:CAS:528:DC%2BC2cXht1ahsb%2FL, PID: 24702282
    • Bollini S, Vieira JM, Howard S, Dube KN, Balmer GM, Smart N, Riley PR (2014) Re-activated adult epicardial progenitor cells are a heterogeneous population molecularly distinct from their embryonic counterparts. Stem Cells Dev 23:1719–1730
    • (2014) Stem Cells Dev , vol.23 , pp. 1719-1730
    • Bollini, S.1    Vieira, J.M.2    Howard, S.3    Dube, K.N.4    Balmer, G.M.5    Smart, N.6    Riley, P.R.7
  • 97
    • 84911392204 scopus 로고    scopus 로고
    • Epicardial origin of resident mesenchymal stem cells in the adult mammalian heart
    • COI: 1:CAS:528:DC%2BC2MXjt1Wnu7s%3D
    • Asli NS, Xaymardan M, Harvey RP (2014) Epicardial origin of resident mesenchymal stem cells in the adult mammalian heart. J Dev Biol 2:117–137
    • (2014) J Dev Biol , vol.2 , pp. 117-137
    • Asli, N.S.1    Xaymardan, M.2    Harvey, R.P.3
  • 98
    • 84861468977 scopus 로고    scopus 로고
    • Cardiac explant-derived cells are regulated by Notch-modulated mesenchymal transition
    • COI: 1:CAS:528:DC%2BC38Xot1Cqtrg%3D, PID: 22662227
    • Zakharova L, Nural-Guvener H, Gaballa MA (2012) Cardiac explant-derived cells are regulated by Notch-modulated mesenchymal transition. PLoS One 7, e37800
    • (2012) PLoS One , vol.7
    • Zakharova, L.1    Nural-Guvener, H.2    Gaballa, M.A.3
  • 99
    • 84869061537 scopus 로고    scopus 로고
    • TGFbeta-dependent epithelial-to-mesenchymal transition is required to generate cardiospheres from human adult heart biopsies
    • COI: 1:CAS:528:DC%2BC38Xhs1Glsb%2FE, PID: 22765842
    • Forte E, Miraldi F, Chimenti I, Angelini F, Zeuner A, Giacomello A, Mercola M, Messina E (2012) TGFbeta-dependent epithelial-to-mesenchymal transition is required to generate cardiospheres from human adult heart biopsies. Stem Cells Dev 21:3081–3090
    • (2012) Stem Cells Dev , vol.21 , pp. 3081-3090
    • Forte, E.1    Miraldi, F.2    Chimenti, I.3    Angelini, F.4    Zeuner, A.5    Giacomello, A.6    Mercola, M.7    Messina, E.8
  • 100
    • 80054687219 scopus 로고    scopus 로고
    • In vitro epithelial-to-mesenchymal transformation in human adult epicardial cells is regulated by TGFbeta-signaling and WT1
    • COI: 1:CAS:528:DC%2BC3MXpvVKrsrw%3D, PID: 21516490
    • Bax NA, van Oorschot AA, Maas S, Braun J, van Tuyn J, de Vries AA, Groot AC, Goumans MJ (2011) In vitro epithelial-to-mesenchymal transformation in human adult epicardial cells is regulated by TGFbeta-signaling and WT1. Basic Res Cardiol 106:829–847
    • (2011) Basic Res Cardiol , vol.106 , pp. 829-847
    • Bax, N.A.1    van Oorschot, A.A.2    Maas, S.3    Braun, J.4    van Tuyn, J.5    de Vries, A.A.6    Groot, A.C.7    Goumans, M.J.8
  • 102
    • 84874573165 scopus 로고    scopus 로고
    • The transcription factors Tbx18 and Wt1 control the epicardial epithelial-mesenchymal transition through bi-directional regulation of Slug in murine primary epicardial cells
    • COI: 1:CAS:528:DC%2BC3sXjvFKhurw%3D, PID: 23469079
    • Takeichi M, Nimura K, Mori M, Nakagami H, Kaneda Y (2013) The transcription factors Tbx18 and Wt1 control the epicardial epithelial-mesenchymal transition through bi-directional regulation of Slug in murine primary epicardial cells. PLoS One 8, e57829
    • (2013) PLoS One , vol.8
    • Takeichi, M.1    Nimura, K.2    Mori, M.3    Nakagami, H.4    Kaneda, Y.5
  • 103
    • 78650017839 scopus 로고    scopus 로고
    • Epicardial cells are missing from the surface of hearts with ischemic cardiomyopathy: a useful clue about the self-renewal potential of the adult human heart?
    • PID: 19176252
    • Di Meglio F, Castaldo C, Nurzynska D, Romano V, Miraglia R, Montagnani S (2010) Epicardial cells are missing from the surface of hearts with ischemic cardiomyopathy: a useful clue about the self-renewal potential of the adult human heart? Int J Cardiol 145:e44–e46
    • (2010) Int J Cardiol , vol.145 , pp. e44-e46
    • Di Meglio, F.1    Castaldo, C.2    Nurzynska, D.3    Romano, V.4    Miraglia, R.5    Montagnani, S.6
  • 104
    • 84922153362 scopus 로고    scopus 로고
    • Cardiac-specific overexpression of human stem cell factor promotes epicardial activation and arteriogenesis after myocardial infarction
    • COI: 1:CAS:528:DC%2BC2cXhsFymurjL, PID: 25107671
    • Xiang FL, Liu Y, Lu X, Jones DL, Feng Q (2014) Cardiac-specific overexpression of human stem cell factor promotes epicardial activation and arteriogenesis after myocardial infarction. Circ Heart Fail 7:831–842
    • (2014) Circ Heart Fail , vol.7 , pp. 831-842
    • Xiang, F.L.1    Liu, Y.2    Lu, X.3    Jones, D.L.4    Feng, Q.5
  • 105
    • 79954793035 scopus 로고    scopus 로고
    • Notch signaling regulates smooth muscle differentiation of epicardium-derived cells
    • COI: 1:CAS:528:DC%2BC3MXktFeks7w%3D, PID: 21252157
    • Grieskamp T, Rudat C, Ludtke TH, Norden J, Kispert A (2011) Notch signaling regulates smooth muscle differentiation of epicardium-derived cells. Circ Res 108:813–823
    • (2011) Circ Res , vol.108 , pp. 813-823
    • Grieskamp, T.1    Rudat, C.2    Ludtke, T.H.3    Norden, J.4    Kispert, A.5
  • 106
    • 79251625088 scopus 로고    scopus 로고
    • A dynamic notch injury response activates epicardium and contributes to fibrosis repair
    • COI: 1:CAS:528:DC%2BC3MXhtlCmsLs%3D, PID: 21106942
    • Russell JL, Goetsch SC, Gaiano NR, Hill JA, Olson EN, Schneider JW (2011) A dynamic notch injury response activates epicardium and contributes to fibrosis repair. Circ Res 108:51–59
    • (2011) Circ Res , vol.108 , pp. 51-59
    • Russell, J.L.1    Goetsch, S.C.2    Gaiano, N.R.3    Hill, J.A.4    Olson, E.N.5    Schneider, J.W.6
  • 107
    • 34247479062 scopus 로고    scopus 로고
    • Thymosin beta4 triggers an epithelial-mesenchymal transition in colorectal carcinoma by upregulating integrin-linked kinase
    • COI: 1:CAS:528:DC%2BD2sXksF2rsLg%3D, PID: 17072345
    • Huang HC, Hu CH, Tang MC, Wang WS, Chen PM, Su Y (2007) Thymosin beta4 triggers an epithelial-mesenchymal transition in colorectal carcinoma by upregulating integrin-linked kinase. Oncogene 26:2781–2790
    • (2007) Oncogene , vol.26 , pp. 2781-2790
    • Huang, H.C.1    Hu, C.H.2    Tang, M.C.3    Wang, W.S.4    Chen, P.M.5    Su, Y.6
  • 108
    • 63549141609 scopus 로고    scopus 로고
    • Thymosin beta4 mediated PKC activation is essential to initiate the embryonic coronary developmental program and epicardial progenitor cell activation in adult mice in vivo
    • COI: 1:CAS:528:DC%2BD1MXktFChurc%3D, PID: 19358334
    • Bock-Marquette I, Shrivastava S, Pipes GC, Thatcher JE, Blystone A, Shelton JM, Galindo CL, Melegh B, Srivastava D, Olson EN et al (2009) Thymosin beta4 mediated PKC activation is essential to initiate the embryonic coronary developmental program and epicardial progenitor cell activation in adult mice in vivo. J Mol Cell Cardiol 46:728–738
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 728-738
    • Bock-Marquette, I.1    Shrivastava, S.2    Pipes, G.C.3    Thatcher, J.E.4    Blystone, A.5    Shelton, J.M.6    Galindo, C.L.7    Melegh, B.8    Srivastava, D.9    Olson, E.N.10
  • 109
    • 33846243239 scopus 로고    scopus 로고
    • Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization
    • COI: 1:CAS:528:DC%2BD2sXjtFGqtA%3D%3D, PID: 17108969
    • Smart N, Risebro CA, Melville AA, Moses K, Schwartz RJ, Chien KR, Riley PR (2007) Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization. Nature 445:177–182
    • (2007) Nature , vol.445 , pp. 177-182
    • Smart, N.1    Risebro, C.A.2    Melville, A.A.3    Moses, K.4    Schwartz, R.J.5    Chien, K.R.6    Riley, P.R.7
  • 110
    • 84901453347 scopus 로고    scopus 로고
    • Thymosin beta4 regulates cardiac valve formation via endothelial-mesenchymal transformation in zebrafish embryos
    • COI: 1:CAS:528:DC%2BC2cXhs1eksr%2FL, PID: 24732964
    • Shin SH, Lee S, Bae JS, Jee JG, Cha HJ, Lee YM (2014) Thymosin beta4 regulates cardiac valve formation via endothelial-mesenchymal transformation in zebrafish embryos. Mol Cells 37:330–336
    • (2014) Mol Cells , vol.37 , pp. 330-336
    • Shin, S.H.1    Lee, S.2    Bae, J.S.3    Jee, J.G.4    Cha, H.J.5    Lee, Y.M.6
  • 111
    • 84899045255 scopus 로고    scopus 로고
    • Cell-cell interaction in the heart via Wnt/beta-catenin pathway after cardiac injury
    • COI: 1:CAS:528:DC%2BC2cXmsVKhsb4%3D, PID: 24591151
    • Deb A (2014) Cell-cell interaction in the heart via Wnt/beta-catenin pathway after cardiac injury. Cardiovasc Res 102:214–223
    • (2014) Cardiovasc Res , vol.102 , pp. 214-223
    • Deb, A.1
  • 112
    • 84857192566 scopus 로고    scopus 로고
    • Wnt1/beta catenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair
    • COI: 1:CAS:528:DC%2BC3MXhsVOitrzJ, PID: 22085926
    • Duan J, Gherghe C, Liu D, Hamlett E, Srikantha L, Rodgers L, Regan JN, Rojas M, Willis M, Leask A et al (2012) Wnt1/beta catenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair. EMBO J 31:429–442
    • (2012) EMBO J , vol.31 , pp. 429-442
    • Duan, J.1    Gherghe, C.2    Liu, D.3    Hamlett, E.4    Srikantha, L.5    Rodgers, L.6    Regan, J.N.7    Rojas, M.8    Willis, M.9    Leask, A.10
  • 113
    • 34250800027 scopus 로고    scopus 로고
    • Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors
    • COI: 1:CAS:528:DC%2BD2sXnsV2lu74%3D, PID: 17576928
    • Kwon C, Arnold J, Hsiao EC, Taketo MM, Conklin BR, Srivastava D (2007) Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors. Proc Natl Acad Sci U S A 104:10894–10899
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 10894-10899
    • Kwon, C.1    Arnold, J.2    Hsiao, E.C.3    Taketo, M.M.4    Conklin, B.R.5    Srivastava, D.6
  • 115
    • 53449092969 scopus 로고    scopus 로고
    • Fate-mapping evidence that hepatic stellate cells are epithelial progenitors in adult mouse livers
    • COI: 1:CAS:528:DC%2BD1cXhtVKmt7rO, PID: 18511600
    • Yang L, Jung Y, Omenetti A, Witek RP, Choi S, Vandongen HM, Huang J, Alpini GD, Diehl AM (2008) Fate-mapping evidence that hepatic stellate cells are epithelial progenitors in adult mouse livers. Stem Cells 26:2104–2113
    • (2008) Stem Cells , vol.26 , pp. 2104-2113
    • Yang, L.1    Jung, Y.2    Omenetti, A.3    Witek, R.P.4    Choi, S.5    Vandongen, H.M.6    Huang, J.7    Alpini, G.D.8    Diehl, A.M.9
  • 117
    • 33947538193 scopus 로고    scopus 로고
    • Epicardium-derived cells in cardiogenesis and cardiac regeneration
    • COI: 1:CAS:528:DC%2BD2sXkslGlsrg%3D, PID: 17380310
    • Winter EM, Gittenberger-de Groot AC (2007) Epicardium-derived cells in cardiogenesis and cardiac regeneration. Cell Mol Life Sci 64:692–703
    • (2007) Cell Mol Life Sci , vol.64 , pp. 692-703
    • Winter, E.M.1    Gittenberger-de Groot, A.C.2
  • 119
    • 0036676445 scopus 로고    scopus 로고
    • Exosomes: composition, biogenesis and function
    • COI: 1:CAS:528:DC%2BD38XlslGru7k%3D, PID: 12154376
    • Thery C, Zitvogel L, Amigorena S (2002) Exosomes: composition, biogenesis and function. Nat Rev Immunol 2:569–579
    • (2002) Nat Rev Immunol , vol.2 , pp. 569-579
    • Thery, C.1    Zitvogel, L.2    Amigorena, S.3
  • 120
    • 67949097489 scopus 로고    scopus 로고
    • Exosomes—vesicular carriers for intercellular communication
    • COI: 1:CAS:528:DC%2BD1MXps1Cltbc%3D, PID: 19442504
    • Simons M, Raposo G (2009) Exosomes—vesicular carriers for intercellular communication. Curr Opin Cell Biol 21:575–581
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 575-581
    • Simons, M.1    Raposo, G.2
  • 121
    • 78649366866 scopus 로고    scopus 로고
    • Circulating microRNAs as biomarkers and potential paracrine mediators of cardiovascular disease
    • COI: 1:CAS:528:DC%2BC3cXhsVKrsb%2FO, PID: 20959591
    • Gupta SK, Bang C, Thum T (2010) Circulating microRNAs as biomarkers and potential paracrine mediators of cardiovascular disease. Circ Cardiovasc Genet 3:484–488
    • (2010) Circ Cardiovasc Genet , vol.3 , pp. 484-488
    • Gupta, S.K.1    Bang, C.2    Thum, T.3
  • 122
    • 84886738545 scopus 로고    scopus 로고
    • Exosomes as new vesicular lipid transporters involved in cell-cell communication and various pathophysiologies
    • COI: 1:CAS:528:DC%2BC3sXhvFWjt7zL, PID: 24140720
    • Record M, Carayon K, Poirot M, Silvente-Poirot S (2014) Exosomes as new vesicular lipid transporters involved in cell-cell communication and various pathophysiologies. Biochim Biophys Acta 1841:108–120
    • (2014) Biochim Biophys Acta , vol.1841 , pp. 108-120
    • Record, M.1    Carayon, K.2    Poirot, M.3    Silvente-Poirot, S.4
  • 123
    • 84878626175 scopus 로고    scopus 로고
    • The cardiovascular exosome: current perspectives and potential
    • COI: 1:CAS:528:DC%2BC3sXmt1Sltb0%3D, PID: 23526783
    • Cosme J, Liu PP, Gramolini AO (2013) The cardiovascular exosome: current perspectives and potential. Proteomics 13:1654–1659
    • (2013) Proteomics , vol.13 , pp. 1654-1659
    • Cosme, J.1    Liu, P.P.2    Gramolini, A.O.3
  • 124
    • 84895444013 scopus 로고    scopus 로고
    • Exosomes and cardiac repair after myocardial infarction
    • COI: 1:CAS:528:DC%2BC2cXhvVSkurg%3D, PID: 24436429
    • Sahoo S, Losordo DW (2014) Exosomes and cardiac repair after myocardial infarction. Circ Res 114:333–344
    • (2014) Circ Res , vol.114 , pp. 333-344
    • Sahoo, S.1    Losordo, D.W.2
  • 125
    • 84895475039 scopus 로고    scopus 로고
    • Role of exosomes in myocardial remodeling
    • PID: 24436427
    • Waldenstrom A, Ronquist G (2014) Role of exosomes in myocardial remodeling. Circ Res 114:315–324
    • (2014) Circ Res , vol.114 , pp. 315-324
    • Waldenstrom, A.1    Ronquist, G.2
  • 126
    • 84895473169 scopus 로고    scopus 로고
    • Exosomes: nanoparticles involved in cardioprotection?
    • COI: 1:CAS:528:DC%2BC2cXhvVSkuro%3D, PID: 24436428
    • Yellon DM, Davidson SM (2014) Exosomes: nanoparticles involved in cardioprotection? Circ Res 114:325–332
    • (2014) Circ Res , vol.114 , pp. 325-332
    • Yellon, D.M.1    Davidson, S.M.2
  • 127
    • 84873713781 scopus 로고    scopus 로고
    • Cardiac progenitor-derived exosomes protect ischemic myocardium from acute ischemia/reperfusion injury
    • COI: 1:CAS:528:DC%2BC3sXhvFSlsrg%3D, PID: 23318173
    • Chen L, Wang Y, Pan Y, Zhang L, Shen C, Qin G, Ashraf M, Weintraub N, Ma G, Tang Y (2013) Cardiac progenitor-derived exosomes protect ischemic myocardium from acute ischemia/reperfusion injury. Biochem Biophys Res Commun 431:566–571
    • (2013) Biochem Biophys Res Commun , vol.431 , pp. 566-571
    • Chen, L.1    Wang, Y.2    Pan, Y.3    Zhang, L.4    Shen, C.5    Qin, G.6    Ashraf, M.7    Weintraub, N.8    Ma, G.9    Tang, Y.10
  • 129
    • 84855999432 scopus 로고    scopus 로고
    • miR-30 inhibits TGF-beta1-induced epithelial-to-mesenchymal transition in hepatocyte by targeting Snail1
    • COI: 1:CAS:528:DC%2BC38XhtFKrsr4%3D, PID: 22227196
    • Zhang J, Zhang H, Liu J, Tu X, Zang Y, Zhu J, Chen J, Dong L, Zhang J (2012) miR-30 inhibits TGF-beta1-induced epithelial-to-mesenchymal transition in hepatocyte by targeting Snail1. Biochem Biophys Res Commun 417:1100–1105
    • (2012) Biochem Biophys Res Commun , vol.417 , pp. 1100-1105
    • Zhang, J.1    Zhang, H.2    Liu, J.3    Tu, X.4    Zang, Y.5    Zhu, J.6    Chen, J.7    Dong, L.8    Zhang, J.9
  • 130
    • 84862645250 scopus 로고    scopus 로고
    • miRNA-29b suppresses prostate cancer metastasis by regulating epithelial-mesenchymal transition signaling
    • COI: 1:CAS:528:DC%2BC38Xms1yrtb0%3D, PID: 22402125
    • Ru P, Steele R, Newhall P, Phillips NJ, Toth K, Ray RB (2012) miRNA-29b suppresses prostate cancer metastasis by regulating epithelial-mesenchymal transition signaling. Mol Cancer Ther 11:1166–1173
    • (2012) Mol Cancer Ther , vol.11 , pp. 1166-1173
    • Ru, P.1    Steele, R.2    Newhall, P.3    Phillips, N.J.4    Toth, K.5    Ray, R.B.6
  • 131
    • 79952283482 scopus 로고    scopus 로고
    • p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs
    • COI: 1:CAS:528:DC%2BC3MXisFKntrg%3D, PID: 21336307
    • Chang CJ, Chao CH, Xia W, Yang JY, Xiong Y, Li CW, Yu WH, Rehman SK, Hsu JL, Lee HH et al (2011) p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs. Nat Cell Biol 13:317–323
    • (2011) Nat Cell Biol , vol.13 , pp. 317-323
    • Chang, C.J.1    Chao, C.H.2    Xia, W.3    Yang, J.Y.4    Xiong, Y.5    Li, C.W.6    Yu, W.H.7    Rehman, S.K.8    Hsu, J.L.9    Lee, H.H.10
  • 132
    • 77649276051 scopus 로고    scopus 로고
    • Myc-modulated miR-9 makes more metastases
    • COI: 1:CAS:528:DC%2BC3cXisFemsLs%3D, PID: 20173743
    • Khew-Goodall Y, Goodall GJ (2010) Myc-modulated miR-9 makes more metastases. Nat Cell Biol 12:209–211
    • (2010) Nat Cell Biol , vol.12 , pp. 209-211
    • Khew-Goodall, Y.1    Goodall, G.J.2
  • 134
    • 84877928478 scopus 로고    scopus 로고
    • Regulation of epithelial-mesenchymal and mesenchymal-epithelial transitions by microRNAs
    • COI: 1:CAS:528:DC%2BC3sXivVWmtL4%3D, PID: 23434068
    • Lamouille S, Subramanyam D, Blelloch R, Derynck R (2013) Regulation of epithelial-mesenchymal and mesenchymal-epithelial transitions by microRNAs. Curr Opin Cell Biol 25:200–207
    • (2013) Curr Opin Cell Biol , vol.25 , pp. 200-207
    • Lamouille, S.1    Subramanyam, D.2    Blelloch, R.3    Derynck, R.4
  • 135
    • 84874157794 scopus 로고    scopus 로고
    • miR-21 promotes fibrogenic epithelial-to-mesenchymal transition of epicardial mesothelial cells involving Programmed Cell Death 4 and Sprouty-1
    • PID: 23441172
    • Bronnum H, Andersen DC, Schneider M, Sandberg MB, Eskildsen T, Nielsen SB, Kalluri R, Sheikh SP (2013) miR-21 promotes fibrogenic epithelial-to-mesenchymal transition of epicardial mesothelial cells involving Programmed Cell Death 4 and Sprouty-1. PLoS One 8:e56280
    • (2013) PLoS One , vol.8 , pp. e56280
    • Bronnum, H.1    Andersen, D.C.2    Schneider, M.3    Sandberg, M.B.4    Eskildsen, T.5    Nielsen, S.B.6    Kalluri, R.7    Sheikh, S.P.8
  • 136
    • 58649087374 scopus 로고    scopus 로고
    • miR-21: a small multi-faceted RNA
    • COI: 1:CAS:528:DC%2BD1MXjsVegurY%3D, PID: 19175699
    • Krichevsky AM, Gabriely G (2009) miR-21: a small multi-faceted RNA. J Cell Mol Med 13:39–53
    • (2009) J Cell Mol Med , vol.13 , pp. 39-53
    • Krichevsky, A.M.1    Gabriely, G.2
  • 137
    • 84899128394 scopus 로고    scopus 로고
    • Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy
    • COI: 1:CAS:528:DC%2BC2cXotVSnsbY%3D, PID: 24743145
    • Bang C, Batkai S, Dangwal S, Gupta SK, Foinquinos A, Holzmann A, Just A, Remke J, Zimmer K, Zeug A et al (2014) Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy. J Clin Invest 124:2136–2146
    • (2014) J Clin Invest , vol.124 , pp. 2136-2146
    • Bang, C.1    Batkai, S.2    Dangwal, S.3    Gupta, S.K.4    Foinquinos, A.5    Holzmann, A.6    Just, A.7    Remke, J.8    Zimmer, K.9    Zeug, A.10
  • 138
    • 78649329252 scopus 로고    scopus 로고
    • Intrapericardial procedures for cardiac regeneration by stem cells: need for minimal invasive access (AttachLifter) to the normal pericardial cavity
    • COI: 1:STN:280:DC%2BC3cbnsFCrsg%3D%3D, PID: 20941468
    • Rupp H, Rupp TP, Alter P, Jung N, Pankuweit S, Maisch B (2010) Intrapericardial procedures for cardiac regeneration by stem cells: need for minimal invasive access (AttachLifter) to the normal pericardial cavity. Herz 35:458–465
    • (2010) Herz , vol.35 , pp. 458-465
    • Rupp, H.1    Rupp, T.P.2    Alter, P.3    Jung, N.4    Pankuweit, S.5    Maisch, B.6


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