Coronary arteries form by developmental reprogramming of venous cells

Nature

Volumn 464, Issue 7288, 2010, Pages 549-553

  Red Horse, Kristy ^a   Ueno, Hiroo ^b   Weissman, Irving L ^b   Krasnow, Mark A ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APELIN; BETA GALACTOSIDASE; EPHRIN RECEPTOR B2; EPHRIN RECEPTOR B4; MESSENGER RNA; VASCULOTROPIN RECEPTOR 3;

BIOENGINEERING; CARDIOVASCULAR DISEASE; CARDIOVASCULAR SYSTEM; CLONE; DISEASE TREATMENT; HISTOLOGY; RODENT;

ANGIOGENESIS; ANIMAL TISSUE; ARTICLE; CELL DEDIFFERENTIATION; CELL DIFFERENTIATION; CELL MIGRATION; CELL TRANSFORMATION; CONTROLLED STUDY; CORONARY ARTERY; CORONARY BLOOD VESSEL; CORONARY VEIN; EMBRYO; HEART CELL CULTURE; HISTOLOGY; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINUS VENOSUS;

ANIMALS; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELL LINEAGE; CORONARY VESSELS; DOWN-REGULATION; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCK-IN TECHNIQUES; MICE; ORGAN CULTURE TECHNIQUES;

MUS;

EID: 77950237662     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature08873     Document Type: Article

References (45)

1. Folkman, J. & Haudenschild, C. Angiogenesis in vitro. Nature 288, 551-556 (1980).
2. Leung, D. W., Cachianes, G., Kuang, W. J., Goeddel, D. V. & Ferrara, N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246, 1306-1309 (1989).
3. Carmeliet, P. Angiogenesisin life, diseaseandmedicine.Nature438, 932-936(2005).
4. Adams, R. H. & Alitalo, K. Molecular regulation of angiogenesis and lymphangiogenesis. Nature Rev. Mol. Cell Biol. 8, 464-478 (2007).
5. Ferrara, N. & Kerbel, R. S. Angiogenesis as a therapeutic target. Nature 438, 967-974 (2005)
6. Folkman, J. Angiogenesis. Annu. Rev. Med. 57, 1-18 (2006).
7. Majesky, M. W. Development of coronary vessels. Curr. Top. Dev. Biol. 62, 225-259 (2004).
8. Lavine, K. J. & Ornitz, D. M. Shared circuitry: developmental signaling cascades regulate both embryonic and adult coronary vasculature. Circ. Res. 104, 159-169 (2009).
9. Smart, N., Dube, K. N. & Riley, P. R. Coronary vessel development and insight towards neovascular therapy. Int. J. Exp. Pathol. 90, 262-283 (2009).
10. World Health Organization. The Global Burden Of Disease: 2004 Update http:// www.who.int/healthinfo/global-burden-disease/2004-report-update/en/ index.htmlæ.
11. Lewis, F. T. The question of sinusoids. Anat. Anz. 25, 261-279 (1904).
12. Grant, R. T. Development of the cardiac coronary vessels in the rabbit. Heart 13, 261-271 (1923).
13. Bennett, H. S. The development of the blood supply to the heart in the embryo pig. Am. J. Anat. 60, 27-53 (1936).
14. Hutchins, G. M., Kessler-Hanna, A. & Moore, G. W. Development of the coronary arteries in the embryonic human heart. Circulation 77, 1250-1257 (1988).
15. Mikawa, T. & Gourdie, R. G. Pericardial mesoderm generates a population of coronary smooth muscle cells migrating into the heart along with ingrowth of the epicardial organ. Dev. Biol. 174, 221-232 (1996).
16. Männer, J. Does the subepicardial mesenchyme contribute myocardioblasts to the myocardium of the chick embryo heart? A quail-chick chimera study tracing the fate of the epicardial primordium. Anat. Rec. 255, 212-226 (1999).
17. Pérez-Pomares, J. M. et al. Origin of coronary endothelial cells from epicardial mesothelium in avian embryos. Int. J. Dev. Biol. 46, 1005-1013 (2002)
18. Kirby, M. L. Cardiac Development (Oxford Univ. Press, 2007).
19. Poelmann, R. E., Gittenberger-de Groot, A. C., Mentink, M. M., Bokenkamp, R. & Hogers, B. Development of the cardiac coronary vascular endothelium, studied with antiendothelial antibodies, in chicken-quail chimeras. Circ. Res. 73, 559-568 (1993).
20. Merki, E. et al.Epicardial retinoid X receptor ais required for myocardial growth and coronary artery formation. Proc. Natl Acad. Sci. USA 102, 18455-18460 (2005).
21. Wilm, B., Ipenberg, A., Hastie, N. D., Burch, J. B. & Bader, D. M. The serosal mesothelium is a major source of smooth muscle cells of the gut vasculature. Development 132, 5317-5328 (2005).
22. Cai, C. L. et al. A myocardial lineage derives from Tbx18 epicardial cells. Nature 454, 104-108 (2008).
23. Zhou, B. et al. Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart. Nature 454, 109-113 (2008).
24. Sheikh, A. Y. et al. In vivo genetic profiling and cellular localization of apelin reveals a hypoxia-sensitive, endothelial-centered pathway activated in ischemic heart failure. Am. J. Physiol. Heart Circ. Physiol. 294, H88-H98 (2008).
25. Kattan, J., Dettman, R. W. & Bristow, J. Formation and remodeling of the coronary vascular bed in the embryonic avian heart. Dev. Dyn. 230, 34-43 (2004).
26. Lavine, K. J. et al. Fibroblast growth factor signals regulate a wave of Hedgehog activation that is essential for coronary vascular development. Genes Dev. 20, 1651-1666 (2006).
27. Hiruma, T. & Hirakow, R. Epicardial formation in embryonic chick heart: computer-aided reconstruction, scanning, and transmission electron microscopic studies. Am. J. Anat. 184, 129-138 (1989).
28. Hellström, M. et al. Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature 445, 776-780 (2007).
29. Kidoya, H. et al. Spatial and temporal role of the apelin/APJ system in the caliber size regulation of blood vessels during angiogenesis. EMBO J. 27, 522-534 (2008).
30. Tammela, T. et al. Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature 454, 656-660 (2008).
31. Suchting, S. et al. The Notch ligand Delta-like4negatively regulates endothelialtipcell formation and vessel branching. Proc. Natl Acad. Sci. USA 104, 3225-3230 (2007).
32. Drake, C. J. & Fleming, P. A. Vasculogenesis in the day 6.5 to 9.5 mouse embryo. Blood 95, 1671-1679 (2000).
33. T2 transgenic mouse: a model for inducible recombination in the endothelium. Dev. Dyn. 235, 3413-3422 (2006).
34. Livet, J. et al. Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system. Nature 450, 56-62 (2007).
35. Lavine, K. J., Long, F., Choi, K., Smith, C. & Ornitz, D. M. Hedgehog signaling to distinct cell types differentially regulates coronary artery and vein development. Development 135, 3161-3171 (2008).
36. Swift, M. R. & Weinstein, B. M. Arterial-venous specification during development. Circ. Res. 104, 576-588 (2009).
37. le Noble, F. et al. Flow regulates arterial-venous differentiation in the chick embryo yolk sac. Development 131, 361-375 (2004).
38. Moyon, D., Pardanaud, L., Yuan, L., Breant, C. & Eichmann, A. Plasticity of endothelial cells during arterial-venous differentiation in the avian embryo. Development 128, 3359-3370 (2001).
39. Othman-Hassan, K. et al. Arterial identity of endothelial cells is controlled by local cues. Dev. Biol. 237, 398-409 (2001).
40. Kudo, F. A. et al. Venous identity is lost but arterial identity is not gained during vein graft adaptation. Arterioscler. Thromb. Vasc. Biol. 27, 1562-1571 (2007).
41. Goldman, S. et al. Long-term patency of saphenous vein and left internal mammary artery grafts after coronary artery bypass surgery: results from a Department of Veterans Affairs Cooperative Study. J. Am. Coll. Cardiol. 44, 2149-2156 (2004).
42. Sabik, J. F. III, Lytle, B. W., Blackstone, E. H., Houghtaling, P. L. & Cosgrove, D. M. Comparison of saphenous vein and internal thoracic artery graft patency by coronary system. Ann. Thorac. Surg. 79, 544-551, discussion 544-551 (2005).
43. Metzger, R. J., Klein, O. D., Martin, G. R. & Krasnow, M. A. The branching programme of mouse lung development. Nature 453, 745-750 (2008).
44. Hayashi, S. & McMahon, A. P. Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/ inactivation in the mouse. Dev. Biol. 244, 305-318 (2002).
45. Zovein, A. C. et al. Fate tracing reveals the endothelial origin of hematopoietic stem cells. Cell Stem Cell 3, 625-636 (2008).