The effects of folic acid on global DNA methylation and colonosphere formation in colon cancer cell lines

Journal of Nutritional Biochemistry

Volumn 26, Issue 8, 2015, Pages 818-826

  Farias, Nathan ^a   Ho, Nelson ^a   Butler, Stacey ^a   Delaney, Leanne ^a   Morrison, Jodi ^a   Shahrzad, Siranoush ^b   Coomber, Brenda L ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b Investigative Science Incorporated   (Canada)

Author keywords

Cancer stem cell; Colonospheres; Colorectal cancer; DNA methylation; DNMT; Folate

Indexed keywords

ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE; CD133 ANTIGEN; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; EPITHELIAL CELL ADHESION MOLECULE; FOLIC ACID; DMAP1 PROTEIN, HUMAN; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA METHYLTRANSFERASE; REPRESSOR PROTEIN;

ARTICLE; CANCER CELL CULTURE; CANCER CELL LINE; CANCER GROWTH; CELL COUNT; CELL PROLIFERATION; COLON CANCER; COLONOSPHERE FORMATION; CONTROLLED STUDY; DNA METHYLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; MTT ASSAY; PHENOTYPE; PROTEIN EXPRESSION; VITAMIN METABOLISM; VITAMIN SUPPLEMENTATION; WESTERN BLOTTING; CANCER STEM CELL; COLON TUMOR; DRUG EFFECTS; GENETICS; HCT116 CELL LINE; METABOLISM; TUMOR CELL LINE;

CELL LINE, TUMOR; CELL PROLIFERATION; COLONIC NEOPLASMS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DNA MODIFICATION METHYLASES; FOLIC ACID; HCT116 CELLS; HUMANS; NEOPLASTIC STEM CELLS; REPRESSOR PROTEINS;

EID: 84931562431     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2015.02.002     Document Type: Article

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