DNA methyltransferase 1 is essential for initiation of the colon cancers

Experimental and Molecular Pathology

Volumn 94, Issue 2, 2013, Pages 322-329

  Morita, Rena ^a,b   Hirohashi, Yoshihiko ^a   Suzuki, Hiromu ^a   Takahashi, Akari ^a   Tamura, Yasuaki ^a   Kanaseki, Takayuki ^a   Asanuma, Hiroko ^a   Inoda, Satoko ^a   Kondo, Toru ^b   Hashino, Satoshi ^b   Hasegawa, Tadashi ^a   Tokino, Takashi ^a   Toyota, Minoru ^a   Asaka, Masahiro ^b   Torigoe, Toshihiko ^a   Sato, Noriyuki ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Cancer stem cell; Colon cancer; DNMT1

Indexed keywords

DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; MESSENGER RNA; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER STEM CELL; COLON CANCER; COLON CARCINOGENESIS; CONTROLLED STUDY; DNMT1 GENE; DNMT3A GENE; DNMT3B GENE; ENZYME ACTIVITY; FEMALE; GENE; GENE FUNCTION; GENE SILENCING; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; TUMOR PROMOTION; TUMOR XENOGRAFT;

ANIMALS; ANTIGENS, CD24; ANTIGENS, CD44; CELL TRANSFORMATION, NEOPLASTIC; COLONIC NEOPLASMS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; GENE KNOCKDOWN TECHNIQUES; HCT116 CELLS; HUMANS; MICE; MICE, INBRED NOD; MICE, SCID; NEOPLASM TRANSPLANTATION; NEOPLASTIC STEM CELLS; RNA INTERFERENCE; RNA, SMALL INTERFERING; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84874501507     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2012.10.004     Document Type: Article

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