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Volumn 132, Issue 2, 2013, Pages

Aberrant methylation of the PTCH1 gene promoter region in aberrant crypt foci

Author keywords

aberrant crypt foci; colorectal neoplasms; methylation; PTCH1

Indexed keywords

MESSENGER RNA; PROTEIN PATCHED 1; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TUMOR SUPPRESSOR PROTEIN;

EID: 84869491549     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.27812     Document Type: Article
Times cited : (27)

References (27)
  • 1
    • 0034100967 scopus 로고    scopus 로고
    • Aberrant crypt foci in colorectal carcinogenesis. Cell and crypt dynamics
    • Roncucci L, Pedroni M, Vaccina F, et al. Aberrant crypt foci in colorectal carcinogenesis. Cell and crypt dynamics. Cell Prolif 2000; 33: 1-18.
    • (2000) Cell Prolif , vol.33 , pp. 1-18
    • Roncucci, L.1    Pedroni, M.2    Vaccina, F.3
  • 3
    • 14844299317 scopus 로고    scopus 로고
    • Role of aberrant crypt foci detected using high-magnification- chromoscopic colonoscopy in human colorectal carcinogenesis
    • Hurlstone DP, Cross SS,. Role of aberrant crypt foci detected using high-magnification-chromoscopic colonoscopy in human colorectal carcinogenesis. J Gastroenterol Hepatol 2005; 20: 173-81.
    • (2005) J Gastroenterol Hepatol , vol.20 , pp. 173-181
    • Hurlstone, D.P.1    Cross, S.S.2
  • 4
    • 17144464406 scopus 로고    scopus 로고
    • Aberrant crypt foci of the colon as precursors of adenoma and cancer
    • Takayama T, Katsuki S, Takahashi Y, et al. Aberrant crypt foci of the colon as precursors of adenoma and cancer. N Engl J Med 1998; 339: 1277-84.
    • (1998) N Engl J Med , vol.339 , pp. 1277-1284
    • Takayama, T.1    Katsuki, S.2    Takahashi, Y.3
  • 5
    • 0033865758 scopus 로고    scopus 로고
    • Sequential and morphological analyses of aberrant crypt foci formation in mice of differing susceptibility to azoxymethane-induced colon carcinogenesis
    • Papanikolaou A, Wang QS, Papanikolaou D, et al. Sequential and morphological analyses of aberrant crypt foci formation in mice of differing susceptibility to azoxymethane-induced colon carcinogenesis. Carcinogenesis (Lond) 2000; 21: 1567-72.
    • (2000) Carcinogenesis (Lond) , vol.21 , pp. 1567-1572
    • Papanikolaou, A.1    Wang, Q.S.2    Papanikolaou, D.3
  • 6
    • 9244221172 scopus 로고    scopus 로고
    • Tissue repair and stem cell renewal in carcinogenesis
    • Beachy PA, Karhadkar SS, Berman DM,. Tissue repair and stem cell renewal in carcinogenesis. Nature 2004; 432: 324-31.
    • (2004) Nature , vol.432 , pp. 324-331
    • Beachy, P.A.1    Karhadkar, S.S.2    Berman, D.M.3
  • 7
    • 77956935129 scopus 로고    scopus 로고
    • Opposite expression patterns of Sonic hedgehog and Indian hedgehog are associated with aberrant methylation status of their promoters in colorectal cancers
    • Fu X, Yang X, Li J, et al. Opposite expression patterns of Sonic hedgehog and Indian hedgehog are associated with aberrant methylation status of their promoters in colorectal cancers. Pathology 2010; 42: 553-9.
    • (2010) Pathology , vol.42 , pp. 553-559
    • Fu, X.1    Yang, X.2    Li, J.3
  • 8
    • 70350458591 scopus 로고    scopus 로고
    • Methylation of PTCH1a gene in a subset of gastric cancers
    • Du P, Ye HR, Gao J, et al. Methylation of PTCH1a gene in a subset of gastric cancers. World J Gastroenterol 2009; 15: 3799-806.
    • (2009) World J Gastroenterol , vol.15 , pp. 3799-3806
    • Du, P.1    Ye, H.R.2    Gao, J.3
  • 9
    • 36248953744 scopus 로고    scopus 로고
    • Hedgehog signaling pathway is inactive in colorectal cancer cell lines
    • Chatel G, Ganeff C, Boussif N, et al. Hedgehog signaling pathway is inactive in colorectal cancer cell lines. Int J Cancer 2007; 121: 2622-7.
    • (2007) Int J Cancer , vol.121 , pp. 2622-2627
    • Chatel, G.1    Ganeff, C.2    Boussif, N.3
  • 10
    • 10744233571 scopus 로고    scopus 로고
    • Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation
    • Van den Brink GR, Bleuming SA, Hardwick JC, et al. Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation. Nat Genet 2004; 36: 277-82.
    • (2004) Nat Genet , vol.36 , pp. 277-282
    • Van Den Brink, G.R.1    Bleuming, S.A.2    Hardwick, J.C.3
  • 11
    • 32044442728 scopus 로고    scopus 로고
    • Expression of hedgehog pathway components in the adult colon
    • Van Den Brink GR, Peppelenbosch MP,. Expression of hedgehog pathway components in the adult colon. Gastroenterology 2006; 130: 619.
    • (2006) Gastroenterology , vol.130 , pp. 619
    • Van Den Brink, G.R.1    Peppelenbosch, M.P.2
  • 12
    • 4143097168 scopus 로고    scopus 로고
    • Expression of Sonic hedgehog genes is altered in colonic neoplasia
    • Oniscu A, James RM, Morris RG, et al. Expression of Sonic hedgehog genes is altered in colonic neoplasia. J Pathol 2004; 203: 909-17.
    • (2004) J Pathol , vol.203 , pp. 909-917
    • Oniscu, A.1    James, R.M.2    Morris, R.G.3
  • 13
    • 32244432266 scopus 로고    scopus 로고
    • Sonic hedgehog mRNA expression by real-time quantitative PCR in normal and tumor tissues from colorectal cancer patients
    • Monzo M, Moreno I, Artells R, et al. Sonic hedgehog mRNA expression by real-time quantitative PCR in normal and tumor tissues from colorectal cancer patients. Cancer Lett 2006; 233: 117-23.
    • (2006) Cancer Lett , vol.233 , pp. 117-123
    • Monzo, M.1    Moreno, I.2    Artells, R.3
  • 14
    • 80052225991 scopus 로고    scopus 로고
    • Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells
    • Mazumdar T, Devecchio J, Agyeman A, et al. Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells. Cancer Res 2011; 71: 5904-14.
    • (2011) Cancer Res , vol.71 , pp. 5904-5914
    • Mazumdar, T.1    Devecchio, J.2    Agyeman, A.3
  • 15
    • 33751337806 scopus 로고    scopus 로고
    • Hedgehog signal pathway is activated in ovarian carcinomas, correlating with cell proliferation: It's inhibition leads to growth suppression and apoptosis
    • Chen X, Horiuchi A, Kikuchi N, et al. Hedgehog signal pathway is activated in ovarian carcinomas, correlating with cell proliferation: it's inhibition leads to growth suppression and apoptosis. Cancer Sci 2007; 98: 68-76.
    • (2007) Cancer Sci , vol.98 , pp. 68-76
    • Chen, X.1    Horiuchi, A.2    Kikuchi, N.3
  • 16
    • 33646480058 scopus 로고    scopus 로고
    • The BH3-only protein, PUMA, is involved in oxaliplatin-induced apoptosis in colon cancer cells
    • Wang X, Li M, Wang J, et al. The BH3-only protein, PUMA, is involved in oxaliplatin-induced apoptosis in colon cancer cells. Biochem Pharmacol 2006; 71: 1540-50.
    • (2006) Biochem Pharmacol , vol.71 , pp. 1540-1550
    • Wang, X.1    Li, M.2    Wang, J.3
  • 19
    • 34247646461 scopus 로고    scopus 로고
    • Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis
    • Morton JP, Mongeau ME, Klimstra DS,. Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis. Proc Natl Acad Sci USA 2007; 104: 5103-8.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 5103-5108
    • Morton, J.P.1    Mongeau, M.E.2    Klimstra, D.S.3
  • 20
    • 74549200943 scopus 로고    scopus 로고
    • Mechanisms of inactivation of PTCH1 gene in nevoid basal cell carcinoma syndrome: Modification of the two-hit hypothesis
    • Pan S, Dong Q, Sun LS, et al. Mechanisms of inactivation of PTCH1 gene in nevoid basal cell carcinoma syndrome: modification of the two-hit hypothesis. Clin Cancer Res 2010; 16: 442-50.
    • (2010) Clin Cancer Res , vol.16 , pp. 442-450
    • Pan, S.1    Dong, Q.2    Sun, L.S.3
  • 21
    • 34247365397 scopus 로고    scopus 로고
    • Unmasking of epigenetically silenced genes reveals DNA promoter methylation and reduced expression of PTCH in breast cancer
    • Wolf I, Bose S, Desmond JC, et al. Unmasking of epigenetically silenced genes reveals DNA promoter methylation and reduced expression of PTCH in breast cancer. Breast Cancer Res Treat 2007; 105: 139-55.
    • (2007) Breast Cancer Res Treat , vol.105 , pp. 139-155
    • Wolf, I.1    Bose, S.2    Desmond, J.C.3
  • 22
    • 0242270878 scopus 로고    scopus 로고
    • Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
    • Thayer SP, di MaGLIano MP, Heiser PW, et al. Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature 2003; 425: 851-6.
    • (2003) Nature , vol.425 , pp. 851-856
    • Thayer, S.P.1    Di Magliano, M.P.2    Heiser, P.W.3
  • 23
    • 0242268525 scopus 로고    scopus 로고
    • Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
    • Berman DM, Karhadkar SS, Maitra A, et al. Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours. Nature 2003; 425: 846-51.
    • (2003) Nature , vol.425 , pp. 846-851
    • Berman, D.M.1    Karhadkar, S.S.2    Maitra, A.3
  • 24
    • 34548580238 scopus 로고    scopus 로고
    • The patched gene is epigenetically regulated in ovarian dermoids and fibromas, but not in basocellular carcinomas
    • Cretnik M, Musani V, Oreskovic S, et al. The patched gene is epigenetically regulated in ovarian dermoids and fibromas, but not in basocellular carcinomas. Int J Mol Med 2007; 19: 875-83.
    • (2007) Int J Mol Med , vol.19 , pp. 875-883
    • Cretnik, M.1    Musani, V.2    Oreskovic, S.3
  • 25
    • 0033864964 scopus 로고    scopus 로고
    • Phenotypic and molecular characteristics of hyperplastic polyposis
    • Rashid A, Houlihan PS, Booker S, et al. Phenotypic and molecular characteristics of hyperplastic polyposis. Gastroenterology 2000; 119: 323-32.
    • (2000) Gastroenterology , vol.119 , pp. 323-332
    • Rashid, A.1    Houlihan, P.S.2    Booker, S.3
  • 26
    • 0036098559 scopus 로고    scopus 로고
    • CpG island methylation in aberrant crypt foci of the colorectum
    • Chan AO, Broaddus RR, Houlihan PS, et al. CpG island methylation in aberrant crypt foci of the colorectum. Am J Pathol 2002; 160: 1823-30.
    • (2002) Am J Pathol , vol.160 , pp. 1823-1830
    • Chan, A.O.1    Broaddus, R.R.2    Houlihan, P.S.3
  • 27
    • 84855180008 scopus 로고    scopus 로고
    • Identification and validation of highly frequent CpG island hypermethylation in colorectal adenomas and carcinomas
    • Oster B, Thorsen K, Lamy P, et al. Identification and validation of highly frequent CpG island hypermethylation in colorectal adenomas and carcinomas. Int J Cancer 2011; 129: 2855-66.
    • (2011) Int J Cancer , vol.129 , pp. 2855-2866
    • Oster, B.1    Thorsen, K.2    Lamy, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.