-
1
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
PMID:12042769
-
Jones PA, Baylin SB. The fundamental role of epigenetic events in cancer. Nat Rev Genet 2002; 3:415-428; PMID:12042769.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
2
-
-
84859731822
-
Epigenetic modifications in cardiovascular disease
-
PMID:22234702
-
Lorenzen JM, Martino F, Thum T. Epigenetic modifications in cardiovascular disease. Basic Res Cardiol 2012; 107:245; PMID:22234702; http://dx.doi.org/10.1007/s00395-012-0245-9.
-
(2012)
Basic Res Cardiol
, vol.107
, pp. 245
-
-
Lorenzen, J.M.1
Martino, F.2
Thum, T.3
-
3
-
-
22844457491
-
DNA methylation and human disease
-
PMID:16136652
-
Robertson KD. DNA methylation and human disease. Nat Rev Genet 2005; 6:597-610; PMID:16136652; http://dx.doi.org/10.1038/nrg1655.
-
(2005)
Nat Rev Genet
, vol.6
, pp. 597-610
-
-
Robertson, K.D.1
-
4
-
-
70149099610
-
Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context
-
PMID:19680444
-
Christensen BC, Houseman EA, Marsit CJ, Zheng S, Wrensch MR, Wiemels JL, et al. Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context. PLoS Genet 2009; 5:1000602; PMID:19680444; http://dx.doi.org/10.1371/journal.pgen.1000602.
-
(2009)
PLoS Genet
, vol.5
, pp. 1000602
-
-
Christensen, B.C.1
Houseman, E.A.2
Marsit, C.J.3
Zheng, S.4
Wrensch, M.R.5
Wiemels, J.L.6
-
5
-
-
46349091799
-
Profiling CpG island field methylation in both morphologically normal and neoplastic human colonic mucosa
-
PMID:18542073
-
Belshaw NJ, Elliott GO, Foxall RJ, Dainty JR, Pal N, Coupe A, et al. Profiling CpG island field methylation in both morphologically normal and neoplastic human colonic mucosa. Br J Cancer 2008; 99:136-142; PMID:18542073; http://dx.doi.org/10.1038/sj.bjc.6604432.
-
(2008)
Br J Cancer
, vol.99
, pp. 136-142
-
-
Belshaw, N.J.1
Elliott, G.O.2
Foxall, R.J.3
Dainty, J.R.4
Pal, N.5
Coupe, A.6
-
6
-
-
33846561107
-
Colorectal cancer protective effects and the dietary micronutrients folate, methionine, vitamins B6, B12, C, E, selenium and lycopene
-
PMID:17176213
-
Kune G, Watson L. Colorectal cancer protective effects and the dietary micronutrients folate, methionine, vitamins B6, B12, C, E, selenium and lycopene. Nutr Cancer 2006; 56:11-21; PMID:17176213; http://dx.doi.org/10.1207/s15327914nc5601_3.
-
(2006)
Nutr Cancer
, vol.56
, pp. 11-21
-
-
Kune, G.1
Watson, L.2
-
7
-
-
41349107815
-
The nutritional prevention of cancer: 400 mcg per day selenium treatment
-
PMID:18444146
-
Reid ME, Duffield-Lillico AJ, Slate E, Natarajan N, Turnbull B, Jacobs E, et al. The nutritional prevention of cancer: 400 mcg per day selenium treatment. Nutr Cancer 2008; 60:155-163; PMID:18444146; http://dx.doi.org/10.1080/01635580701684856.
-
(2008)
Nutr Cancer
, vol.60
, pp. 155-163
-
-
Reid, M.E.1
Duffield-Lillico, A.J.2
Slate, E.3
Natarajan, N.4
Turnbull, B.5
Jacobs, E.6
-
8
-
-
34249730020
-
Efficacy of folic acid supplementation in stroke prevention: A meta-analysis
-
PMID:17544768
-
Wang X, Qin X, Demirtas H, Li J, Mao G, Huo Y, et al. Efficacy of folic acid supplementation in stroke prevention: a meta-analysis. Lancet 2007; 369:1876-1882; PMID:17544768; http://dx.doi.org/10.1016/S0140-6736(07)60854-X.
-
(2007)
Lancet
, vol.369
, pp. 1876-1882
-
-
Wang, X.1
Qin, X.2
Demirtas, H.3
Li, J.4
Mao, G.5
Huo, Y.6
-
9
-
-
84859211841
-
Selenium and human health
-
Rayman MP. Selenium and human health. Lancet 2012; 379:1256-1268; http://dx.doi.org/10.1016/S0140-6736(11)61452-9
-
(2012)
Lancet
, vol.379
, pp. 1256-1268
-
-
Rayman, M.P.1
-
10
-
-
42149121986
-
Homocysteine, B-vitamins and CVD
-
PMID:18412997
-
McNulty H, Pentieva K, Hoey L, Ward M. Homocysteine, B-vitamins and CVD. Proc Nutr Soc 2008; 67:232-237; PMID:18412997; http://dx.doi.org/10.1017/S0029665108007076.
-
(2008)
Proc Nutr Soc
, vol.67
, pp. 232-237
-
-
McNulty, H.1
Pentieva, K.2
Hoey, L.3
Ward, M.4
-
11
-
-
19844371353
-
Cell and stage of transformation-specific effects of folate deficiency on methionine cycle intermediates and DNA methylation in an in vitro model
-
PMID:15695236
-
Stempak JM, Sohn KJ, Chiang EP, Shane B, Kim YI. Cell and stage of transformation-specific effects of folate deficiency on methionine cycle intermediates and DNA methylation in an in vitro model. Carcinogenesis 2005; 26:981-990; PMID:15695236; http://dx.doi.org/10.1093/carcin/bgi037.
-
(2005)
Carcinogenesis
, vol.26
, pp. 981-990
-
-
Stempak, J.M.1
Sohn, K.J.2
Chiang, E.P.3
Shane, B.4
Kim, Y.I.5
-
12
-
-
0036200864
-
Studies of methionine cycle intermediates (SAM, SAH), DNA methylation and the impact of folate deficiency on tumor numbers in Min mice
-
PMID:11756224
-
Sibani S, Melnyk S, Pogribny IP, Wang W, Hiou-Tim F, Deng L, et al. Studies of methionine cycle intermediates (SAM, SAH), DNA methylation and the impact of folate deficiency on tumor numbers in Min mice. Carcinogenesis 2002; 23:61-65; PMID:11756224; http://dx.doi.org/10.1093/carcin/23.1.61.
-
(2002)
Carcinogenesis
, vol.23
, pp. 61-65
-
-
Sibani, S.1
Melnyk, S.2
Pogribny, I.P.3
Wang, W.4
Hiou-Tim, F.5
Deng, L.6
-
13
-
-
33646896927
-
Differential effects of dietary selenium (Se) and folate on methyl metabolism in liver and colon of rats
-
PMID:16632891
-
Uthus EO, Ross SA, Davis CD. Differential effects of dietary selenium (Se) and folate on methyl metabolism in liver and colon of rats. Biol Trace Elem Res 2006; 109:201-214; PMID:16632891; http://dx.doi.org/10.1385/BTER:109:3:201.
-
(2006)
Biol Trace Elem Res
, vol.109
, pp. 201-214
-
-
Uthus, E.O.1
Ross, S.A.2
Davis, C.D.3
-
14
-
-
84862248102
-
Folate and DNA methylation: A review of molecular mechanisms and the evidence for folate's role
-
PMID:22332098
-
Crider KS, Yang TP, Berry RJ, Bailey LB. Folate and DNA methylation: a review of molecular mechanisms and the evidence for folate's role. Adv Nutr 2012; 3:21-38; PMID:22332098.
-
(2012)
Adv Nutr
, vol.3
, pp. 21-38
-
-
Crider, K.S.1
Yang, T.P.2
Berry, R.J.3
Bailey, L.B.4
-
15
-
-
84863011800
-
Nutritional influences on epigenetics and age-related disease
-
PMID:22051144
-
Park LK, Friso S, Choi SW. Nutritional influences on epigenetics and age-related disease. Proc Nutr Soc 2012; 71:75-83; PMID:22051144; http://dx.doi.org/10.1017/S0029665111003302.
-
(2012)
Proc Nutr Soc
, vol.71
, pp. 75-83
-
-
Park, L.K.1
Friso, S.2
Choi, S.W.3
-
16
-
-
0030695338
-
Folate intake in Europe: Recommended, actual and desired intake
-
PMID:9347284
-
de Bree A, van Dusseldorp M, Brouwer IA, van het Hof KH, Steegers-Theunissen RP. Folate intake in Europe: recommended, actual and desired intake. Eur J Clin Nutr 1997; 51:643-660; PMID:9347284; http://dx.doi.org/10.1038/sj.ejcn.1600467.
-
(1997)
Eur J Clin Nutr
, vol.51
, pp. 643-660
-
-
de Bree, A.1
van Dusseldorp, M.2
Brouwer, I.A.3
van het Hof, K.H.4
Steegers-Theunissen, R.P.5
-
17
-
-
23044466031
-
Quantitative assay of senescence-associated beta-galactosidase activity in mammalian cell extracts
-
PMID:16004951
-
Gary RK, Kindell SM. Quantitative assay of senescence-associated beta-galactosidase activity in mammalian cell extracts. Anal Biochem 2005; 343:329-334; PMID:16004951; http://dx.doi.org/10.1016/j.ab.2005.06.003.
-
(2005)
Anal Biochem
, vol.343
, pp. 329-334
-
-
Gary, R.K.1
Kindell, S.M.2
-
18
-
-
29244490041
-
Analysis of repetitive element DNA methylation by MethyLight
-
PMID:16326863
-
Weisenberger DJ, Campan M, Long TI, Kim M, Woods C, Fiala E, et al. Analysis of repetitive element DNA methylation by MethyLight. Nucleic Acids Res 2005; 33:6823-6836; PMID:16326863; http://dx.doi.org/10.1093/nar/gki987.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 6823-6836
-
-
Weisenberger, D.J.1
Campan, M.2
Long, T.I.3
Kim, M.4
Woods, C.5
Fiala, E.6
-
19
-
-
0035172715
-
Intracellular S-adenosylhomocysteine concentrations predict global DNA hypomethylation in tissues of methyl-deficient cystathionine beta-synthase heterozygous mice
-
PMID:11694601
-
Caudill MA, Wang JC, Melnyk S, Pogribny IP, Jernigan S, Collins MD, et al. Intracellular S-adenosylhomocysteine concentrations predict global DNA hypomethylation in tissues of methyl-deficient cystathionine beta-synthase heterozygous mice. J Nutr 2001; 131:2811-2818; PMID:11694601.
-
(2001)
J Nutr
, vol.131
, pp. 2811-2818
-
-
Caudill, M.A.1
Wang, J.C.2
Melnyk, S.3
Pogribny, I.P.4
Jernigan, S.5
Collins, M.D.6
-
20
-
-
33744761589
-
Long-range allosteric interactions between the folate and methionine cycles stabilize DNA methylation reaction rate
-
PMID:17998813
-
Nijhout HF, Reed MC, Anderson DF, Mattingly JC, James SJ, Ulrich CM. Long-range allosteric interactions between the folate and methionine cycles stabilize DNA methylation reaction rate. Epigenetics 2006;1:81-87; PMID:17998813; http://dx.doi.org/10.4161/epi.1.2.2677.
-
(2006)
Epigenetics
, vol.1
, pp. 81-87
-
-
Nijhout, H.F.1
Reed, M.C.2
Anderson, D.F.3
Mattingly, J.C.4
James, S.J.5
Ulrich, C.M.6
-
21
-
-
11244333118
-
A mathematical model of the folate cycle: New insights into folate homeostasis
-
PMID:15496403
-
Nijhout HF, Reed MC, Budu P, Ulrich CM. A mathematical model of the folate cycle: new insights into folate homeostasis. J Biol Chem 2004; 279:55008-55016; PMID:15496403; http://dx.doi.org/10.1074/jbc.M410818200.
-
(2004)
J Biol Chem
, vol.279
, pp. 55008-55016
-
-
Nijhout, H.F.1
Reed, M.C.2
Budu, P.3
Ulrich, C.M.4
-
22
-
-
66149167311
-
Folate supplementation limits the aggressiveness of glioma via the remethylation of DNA repeats element and genes governing apoptosis and proliferation
-
PMID:19451595
-
Hervouet E, Debien E, Campion L, Charbord J, Menanteau J, Vallette FM, et al. Folate supplementation limits the aggressiveness of glioma via the remethylation of DNA repeats element and genes governing apoptosis and proliferation. Clin Cancer Res 2009; 15:3519-29; PMID:19451595; http://dx.doi.org/10.1158/1078-0432.CCR-08-2062.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3519-3529
-
-
Hervouet, E.1
Debien, E.2
Campion, L.3
Charbord, J.4
Menanteau, J.5
Vallette, F.M.6
-
23
-
-
79955510962
-
Genes methylated by DNA methyltransferase 3b are similar in mouse intestine and human colon cancer
-
PMID:21490393
-
Steine EJ, Ehrich M, Bell GW, Raj A, Reddy S, van Oudenaarden A, et al. Genes methylated by DNA methyltransferase 3b are similar in mouse intestine and human colon cancer. J Clin Invest 2011; 121:1748-1752; PMID:21490393; http://dx.doi.org/10.1172/JCI43169.
-
(2011)
J Clin Invest
, vol.121
, pp. 1748-1752
-
-
Steine, E.J.1
Ehrich, M.2
Bell, G.W.3
Raj, A.4
Reddy, S.5
van Oudenaarden, A.6
-
24
-
-
78650352867
-
Association between folate levels and CpG Island hypermethylation in normal colorectal mucosa
-
PMID:21149331
-
Wallace K, Grau MV, Levine AJ, Shen L, Hamdan R, Chen X, et al. Association between folate levels and CpG Island hypermethylation in normal colorectal mucosa. Cancer Prev Res (Phila) 2010; 3:1552-1564; PMID:21149331; http://dx.doi.org/10.1158/1940-6207.CAPR-10-0047.
-
(2010)
Cancer Prev Res (Phila)
, vol.3
, pp. 1552-1564
-
-
Wallace, K.1
Grau, M.V.2
Levine, A.J.3
Shen, L.4
Hamdan, R.5
Chen, X.6
-
25
-
-
40549095695
-
Is folic acid good for everyone?
-
PMID:18326588
-
Smith AD, Kim YI, Refsum H. Is folic acid good for everyone? Am J Clin Nutr 2008; 87:517-533; PMID:18326588.
-
(2008)
Am J Clin Nutr
, vol.87
, pp. 517-533
-
-
Smith, A.D.1
Kim, Y.I.2
Refsum, H.3
-
26
-
-
39149091066
-
Environment, diet and CpG island methylation: Epigenetic signals in gastrointestinal neoplasia
-
PMID:17976883
-
Johnson IT, Belshaw NJ. Environment, diet and CpG island methylation: epigenetic signals in gastrointestinal neoplasia. Food Chem Toxicol 2008; 46:1346-1359; PMID:17976883; http://dx.doi.org/10.1016/j.fct.2007.09.101
-
(2008)
Food Chem Toxicol
, vol.46
, pp. 1346-1359
-
-
Johnson, I.T.1
Belshaw, N.J.2
-
27
-
-
27144538978
-
Genomic alterations in cultured human embryonic stem cells
-
PMID:16142235
-
Maitra A, Arking DE, Shivapurkar N, Ikeda M, Stastny V, Kassauei K, et al. Genomic alterations in cultured human embryonic stem cells. Nat Genet 2005; 37:1099-1103; PMID:16142235; http://dx.doi.org/10.1038/ng1631.
-
(2005)
Nat Genet
, vol.37
, pp. 1099-1103
-
-
Maitra, A.1
Arking, D.E.2
Shivapurkar, N.3
Ikeda, M.4
Stastny, V.5
Kassauei, K.6
-
28
-
-
0142185046
-
Age-related epigenetic changes and the immune system
-
PMID:14585281
-
Issa JP. Age-related epigenetic changes and the immune system. Clin Immunol 2003; 109:103-108; PMID:14585281; http://dx.doi.org/10.1016/S1521-6616(03)00203-1.
-
(2003)
Clin Immunol
, vol.109
, pp. 103-108
-
-
Issa, J.P.1
-
29
-
-
0028001087
-
Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon
-
PMID:7951326
-
Issa JP, Ottaviano YL, Celano P, Hamilton SR, Davidson NE, Baylin SB. Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon. Nat Genet 1994; 7:536-540; PMID:7951326; http://dx.doi.org/10.1038/ng0894-536.
-
(1994)
Nat Genet
, vol.7
, pp. 536-540
-
-
Issa, J.P.1
Ottaviano, Y.L.2
Celano, P.3
Hamilton, S.R.4
Davidson, N.E.5
Baylin, S.B.6
-
30
-
-
0032831285
-
Methylation of the estrogen receptor gene is associated with aging and atherosclerosis in the cardiovascular system
-
PMID:10615426
-
Post WS, Goldschmidt-Clermont PJ, Wilhide CC, Heldman AW, Sussman MS, Ouyang P, et al. Methylation of the estrogen receptor gene is associated with aging and atherosclerosis in the cardiovascular system. Cardiovasc Res 1999; 43:985-991; PMID:10615426; http://dx.doi.org/10.1016/S0008-6363(99)00153-4.
-
(1999)
Cardiovasc Res
, vol.43
, pp. 985-991
-
-
Post, W.S.1
Goldschmidt-Clermont, P.J.2
Wilhide, C.C.3
Heldman, A.W.4
Sussman, M.S.5
Ouyang, P.6
-
32
-
-
24044507638
-
Biochemical indicators of B vitamin status in the US population after folic acid fortification: Results from the National Health and Nutrition Examination Survey 1999-2000
-
PMID:16087991
-
Pfeiffer CM, Caudill SP, Gunter EW, Osterloh J, Sampson EJ. Biochemical indicators of B vitamin status in the US population after folic acid fortification: results from the National Health and Nutrition Examination Survey 1999-2000. Am J Clin Nutr 2005; 82:442-450; PMID:16087991.
-
(2005)
Am J Clin Nutr
, vol.82
, pp. 442-450
-
-
Pfeiffer, C.M.1
Caudill, S.P.2
Gunter, E.W.3
Osterloh, J.4
Sampson, E.J.5
-
33
-
-
4644245485
-
Comparison of the serum selenium content of healthy adults living in the Antwerp region (Belgium) with recent literature data
-
PMID:15487770
-
van Cauwenbergh R, Robberecht H, Van Vlaslaer V, Deelstra H. Comparison of the serum selenium content of healthy adults living in the Antwerp region (Belgium) with recent literature data. J Trace Elem Med Biol 2004; 18:99-112; PMID:15487770; http://dx.doi.org/10.1016/j.jtemb.2004.04.004.
-
(2004)
J Trace Elem Med Biol
, vol.18
, pp. 99-112
-
-
van Cauwenbergh, R.1
Robberecht, H.2
van Vlaslaer, V.3
Deelstra, H.4
-
34
-
-
0033178297
-
Confluenceinduced alterations in CpG island methylation in cultured normal human fibroblasts
-
PMID:10454622
-
Pieper RO, Lester KA, Fanton CP. Confluenceinduced alterations in CpG island methylation in cultured normal human fibroblasts. Nucleic Acids Res 1999; 27:3229-3235; PMID:10454622; http://dx.doi.org/10.1093/nar/27.15.3229.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 3229-3235
-
-
Pieper, R.O.1
Lester, K.A.2
Fanton, C.P.3
-
35
-
-
4444246516
-
Use of DNA from human stools to detect aberrant CpG island methylation of genes implicated in colorectal cancer
-
PMID:15342451
-
Belshaw NJ, Elliott GO, Williams EA, Bradburn DM, Mills SJ, Mathers JC, et al. Use of DNA from human stools to detect aberrant CpG island methylation of genes implicated in colorectal cancer. Cancer Epidemiol Biomarkers Prev 2004; 13:1495-1501; PMID:15342451
-
(2004)
Cancer Epidemiol Biomarkers Prev
, vol.13
, pp. 1495-1501
-
-
Belshaw, N.J.1
Elliott, G.O.2
Williams, E.A.3
Bradburn, D.M.4
Mills, S.J.5
Mathers, J.C.6
-
36
-
-
34547812688
-
Methylation levels of LINE-1 repeats and CpG island loci are inversely related in normal colonic mucosa
-
PMID:17640302
-
Iacopetta B, Grieu F, Phillips M, Ruszkiewicz A, Moore J, Minamoto T, et al. Methylation levels of LINE-1 repeats and CpG island loci are inversely related in normal colonic mucosa. Cancer Sci 2007; 98:1454-1460; PMID:17640302; http://dx.doi.org/10.1111/j.1349-7006.2007.00548.x.
-
(2007)
Cancer Sci
, vol.98
, pp. 1454-1460
-
-
Iacopetta, B.1
Grieu, F.2
Phillips, M.3
Ruszkiewicz, A.4
Moore, J.5
Minamoto, T.6
-
37
-
-
0035812987
-
Reversed-phase high-performance liquid chromatography procedure for the simultaneous determination of S-adenosyl-L-methionine and S-adenosyl-Lhomocysteine in mouse liver and the effect of methionine on their concentrations
-
PMID:11589459
-
Wang W, Kramer PM, Yang S, Pereira MA, Tao L. Reversed-phase high-performance liquid chromatography procedure for the simultaneous determination of S-adenosyl-L-methionine and S-adenosyl-Lhomocysteine in mouse liver and the effect of methionine on their concentrations. J Chromatogr B Biomed Sci Appl 2001; 762:59-65; PMID:11589459; http://dx.doi.org/10.1016/S0378-4347(01)00341-3.
-
(2001)
J Chromatogr B Biomed Sci Appl
, vol.762
, pp. 59-65
-
-
Wang, W.1
Kramer, P.M.2
Yang, S.3
Pereira, M.A.4
Tao, L.5
|