The role of the insulin/IGF system in cancer: Lessons learned from clinical trials and the energy balance-cancer link

Frontiers in Endocrinology

Volumn 6, Issue MAY, 2015, Pages

  Bowers, Laura W ^a   Rossi, Emily L ^a   O'Flanagan, Ciara H ^a   De Graffenried, Linda A ^b   Hursting, Stephen D ^a  

^a IL   (United States)

^b The University of Texas at Austin   (United States)

Author keywords

Biomarkers; Energy balance; Insulin; Insulin like growth factor; Obesity

Indexed keywords

1 [4 [(5 CYCLOPROPYL 1H PYRAZOL 3 YL) AMINO] PYRROLO [2, 1 F] [1, 2, 4] TRIAZIN 2 YL] N (6 FLUORO 3 PYRIDINYL) 2 METHYL 2 PYRROLIDINECARBOXAMIDE; AVE 1642; BINDING PROTEIN; C PEPTIDE; CIXUTUMUMAB; DALOTUZUMAB; DUSIGITUMAB; ERLOTINIB; EVEROLIMUS; FIGITUMUMAB; GANITUMAB; GROWTH HORMONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIGAND; LINSITINIB; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PHOSPHATIDYLINOSITOL 3 KINASE; R 1507; ROBATUMUMAB; SOMATOMEDIN; SOMATOMEDIN B RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG;

ANGIOGENESIS; BREAST CANCER; CANCER GROWTH; CANCER RISK; CELL METABOLISM; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; ENERGY BALANCE; HUMAN; INFLAMMATION; META ANALYSIS (TOPIC); NEOPLASM; OBESITY; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); PROTEIN EXPRESSION; REVIEW; SIGNAL TRANSDUCTION; TUMOR GROWTH;

EID: 84930939846     PISSN: None     EISSN: 16642392     Source Type: Journal    
DOI: 10.3389/fendo.2015.00077     Document Type: Review

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