-
1
-
-
2942554887
-
Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002
-
Hedley, A.A., C.L. Ogden, C.L. Johnson, et al 2004. Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002. JAMA 291: 2847-2850.
-
(2004)
JAMA
, vol.291
, pp. 2847-2850
-
-
Hedley, A.A.1
Ogden, C.L.2
Johnson, C.L.3
-
2
-
-
33846422032
-
Obesity and diabetes in the developing world - a growing challenge
-
Hossain, P., B. Kawar, & M. El Nahas 2007. Obesity and diabetes in the developing world - a growing challenge. N. Engl. J. Med. 356: 213-215.
-
(2007)
N. Engl. J. Med.
, vol.356
, pp. 213-215
-
-
Hossain, P.1
Kawar, B.2
El Nahas, M.3
-
3
-
-
0037464510
-
Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults
-
Calle, E.E., C. Rodriguez, K. Walker-Thurmond & M.J. Thun 2003. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N. Engl. J. Med. 348: 1625-1638.
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 1625-1638
-
-
Calle, E.E.1
Rodriguez, C.2
Walker-Thurmond, K.3
Thun, M.J.4
-
4
-
-
33845544078
-
Relationship of metabolic risk factors and development of cardiovascular disease and diabetes
-
Haffner, S.M. 2006. Relationship of metabolic risk factors and development of cardiovascular disease and diabetes. Obesity 14(Suppl 3): 121S-127S.
-
(2006)
Obesity
, vol.14
, Issue.SUPPL. 3
-
-
Haffner, S.M.1
-
5
-
-
0028917432
-
Weight gain as a risk factor for clinical diabetes mellitus in women
-
Colditz, G.A., W.C. Willett, A. Rotnitzky & J.E. Manson 1995. Weight gain as a risk factor for clinical diabetes mellitus in women. Ann. Int. Med. 122: 481-486.
-
(1995)
Ann. Int. Med.
, vol.122
, pp. 481-486
-
-
Colditz, G.A.1
Willett, W.C.2
Rotnitzky, A.3
Manson, J.E.4
-
9
-
-
0032572722
-
Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
-
Lord, G.M., G. Matarese, J.K. Howard, et al 1998. Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression. Nature 394: 897-901.
-
(1998)
Nature
, vol.394
, pp. 897-901
-
-
Lord, G.M.1
Matarese, G.2
Howard, J.K.3
-
10
-
-
0242329861
-
Leptin stimulates esophageal adenocarcinoma growth by nonapoptotic mechanisms
-
Somasundar, P., D. Riggs, B. Jackson, et al 2003. Leptin stimulates esophageal adenocarcinoma growth by nonapoptotic mechanisms. Am. J. Surg. 186: 575-578.
-
(2003)
Am. J. Surg.
, vol.186
, pp. 575-578
-
-
Somasundar, P.1
Riggs, D.2
Jackson, B.3
-
11
-
-
70350500225
-
STATs in cancer inflammation and immunity: a leading role for STAT3
-
Yu, H., D. Pardoll & R. Jove 2009. STATs in cancer inflammation and immunity: a leading role for STAT3. Nature Rev. 9: 798-809.
-
(2009)
Nature Rev.
, vol.9
, pp. 798-809
-
-
Yu, H.1
Pardoll, D.2
Jove, R.3
-
14
-
-
0035051194
-
Leptin is associated with increased prostate cancer risk: a nested case-referent study
-
Stattin, P., S. Soderberg, G. Hallmans, et al 2001. Leptin is associated with increased prostate cancer risk: a nested case-referent study. J. Clin. Endocrinol. Metab. 86: 1341-1345.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 1341-1345
-
-
Stattin, P.1
Soderberg, S.2
Hallmans, G.3
-
15
-
-
34547741589
-
Adipokines as endocrine, paracrine, and autocrine factors in breast cancer risk and progression
-
Vona-Davis, L. & D.P. Rose 2007. Adipokines as endocrine, paracrine, and autocrine factors in breast cancer risk and progression. Endocr.-Relat. Cancer 14: 189-206.
-
(2007)
Endocr.-Relat. Cancer
, vol.14
, pp. 189-206
-
-
Vona-Davis, L.1
Rose, D.P.2
-
16
-
-
0742277837
-
Plasma leptin and colorectal cancer risk: a prospective study in Northern Sweden
-
Stattin, P., R. Palmqvist, S. Soderberg, et al 2003. Plasma leptin and colorectal cancer risk: a prospective study in Northern Sweden. Oncol. Rep. 10: 2015-2021.
-
(2003)
Oncol. Rep.
, vol.10
, pp. 2015-2021
-
-
Stattin, P.1
Palmqvist, R.2
Soderberg, S.3
-
17
-
-
0742270445
-
Obesity and colon cancer: does leptin provide a link?
-
Stattin, P., A. Lukanova, C. Biessy, et al 2004. Obesity and colon cancer: does leptin provide a link? Int. J. Cancer 109: 149-152.
-
(2004)
Int. J. Cancer
, vol.109
, pp. 149-152
-
-
Stattin, P.1
Lukanova, A.2
Biessy, C.3
-
19
-
-
56049083633
-
Leptin promotes motility and invasiveness in human colon cancer cells by activating multiple signal-transduction pathways
-
Jaffe, T. & B. Schwartz 2008. Leptin promotes motility and invasiveness in human colon cancer cells by activating multiple signal-transduction pathways. Int. J. Cancer 123: 2543-2556.
-
(2008)
Int. J. Cancer
, vol.123
, pp. 2543-2556
-
-
Jaffe, T.1
Schwartz, B.2
-
20
-
-
0036177867
-
Control of energy homeostasis and insulin action by adipocyte hormones: leptin, acylation stimulating protein, and adiponectin
-
Havel, P.J. 2002. Control of energy homeostasis and insulin action by adipocyte hormones: leptin, acylation stimulating protein, and adiponectin. Curr. Opin. Lipidol. 13: 51-59.
-
(2002)
Curr. Opin. Lipidol.
, vol.13
, pp. 51-59
-
-
Havel, P.J.1
-
21
-
-
78249280002
-
Adiponectin and adiponectin receptor in relation to colorectal cancer progression
-
Byeon, J.-S., J.-Y. Jeong, M.J. Kim, et al 2010. Adiponectin and adiponectin receptor in relation to colorectal cancer progression. Int. J. Cancer 127: 2758-2767.
-
(2010)
Int. J. Cancer
, vol.127
, pp. 2758-2767
-
-
Byeon, J.-S.1
Jeong, J.-Y.2
Kim, M.J.3
-
22
-
-
56749116073
-
Serum adiponectin in relation to endometrial cancer and endometrial hyperplasia with atypia in obese women
-
Rzepka-Gorska, I., R. Bedner, A. Cymbaluk-Ploska & A. Chudecka-Glaz 2008. Serum adiponectin in relation to endometrial cancer and endometrial hyperplasia with atypia in obese women. Eur. J. Gynaecol. Oncol. 29: 594-597.
-
(2008)
Eur. J. Gynaecol. Oncol.
, vol.29
, pp. 594-597
-
-
Rzepka-Gorska, I.1
Bedner, R.2
Cymbaluk-Ploska, A.3
Chudecka-Glaz, A.4
-
23
-
-
35948957490
-
Anthropometric measures, plasma adiponectin, and breast cancer risk
-
Tian, Y.F., C.H. Chu, M.H. Wu, et al 2007. Anthropometric measures, plasma adiponectin, and breast cancer risk. Endocr.-Relat. Cancer 14: 669-677.
-
(2007)
Endocr.-Relat. Cancer
, vol.14
, pp. 669-677
-
-
Tian, Y.F.1
Chu, C.H.2
Wu, M.H.3
-
24
-
-
27944506001
-
Low plasma adiponectin levels and risk of colorectal cancer in men: a prospective study
-
Wei, E.K., E. Giovannucci, C.S. Fuchs, W.C. Willett & C.S. Mantzoros 2005. Low plasma adiponectin levels and risk of colorectal cancer in men: a prospective study. J. Natl. Cancer Inst. 97: 1688-1694.
-
(2005)
J. Natl. Cancer Inst.
, vol.97
, pp. 1688-1694
-
-
Wei, E.K.1
Giovannucci, E.2
Fuchs, C.S.3
Willett, W.C.4
Mantzoros, C.S.5
-
25
-
-
51649102135
-
Relationship between serum adiponectin and prostate cancer grade
-
Sher, D.J., W.K. Oh, S. Jacobus, et al 2008. Relationship between serum adiponectin and prostate cancer grade. Prostate 68: 1592-1598.
-
(2008)
Prostate
, vol.68
, pp. 1592-1598
-
-
Sher, D.J.1
Oh, W.K.2
Jacobus, S.3
-
26
-
-
40349108448
-
Adiponectin in relation to malignancies: a review of existing basic research and clinical evidence
-
Barb, D. et al Adiponectin in relation to malignancies: a review of existing basic research and clinical evidence. Am. J. Clin. Nutr. 86: 858S-866S.
-
Am. J. Clin. Nutr.
, vol.86
-
-
Barb, D.1
-
27
-
-
71449120059
-
Insulin resistance and hyperinsulinaemia in the development and progression of cancer
-
Godsland, I.F. 2010. Insulin resistance and hyperinsulinaemia in the development and progression of cancer. Clin. Sci. 118: 315-332.
-
(2010)
Clin. Sci.
, vol.118
, pp. 315-332
-
-
Godsland, I.F.1
-
28
-
-
0033849777
-
Obesity and insulin resistance
-
Kahn, B.B. & J.S. Flier 2000. Obesity and insulin resistance. J. Clin. Invest. 106: 473-481.
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 473-481
-
-
Kahn, B.B.1
Flier, J.S.2
-
29
-
-
47349117519
-
Hyper-insulinaemia and cancer, meta-analyses of epidemiological studies
-
Pisani, P. 2008. Hyper-insulinaemia and cancer, meta-analyses of epidemiological studies. Arch. Physiol. Biochem. 114: 63-70.
-
(2008)
Arch. Physiol. Biochem.
, vol.114
, pp. 63-70
-
-
Pisani, P.1
-
30
-
-
0141574296
-
Adipose tissue as an endocrine organ: impact on insulin resistance
-
Jazet, I.M., H. Pijl & A.E. Meinders 2003. Adipose tissue as an endocrine organ: impact on insulin resistance. Neth. J. Med. 61: 194-212.
-
(2003)
Neth. J. Med.
, vol.61
, pp. 194-212
-
-
Jazet, I.M.1
Pijl, H.2
Meinders, A.E.3
-
31
-
-
33845881411
-
Mechanisms linking obesity to insulin resistance and type 2 diabetes
-
Kahn, S.E., R.L. Hull & K.M. Utzschneider 2006. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 444: 840-846.
-
(2006)
Nature
, vol.444
, pp. 840-846
-
-
Kahn, S.E.1
Hull, R.L.2
Utzschneider, K.M.3
-
33
-
-
33750900938
-
Consumption of sugar and sugar-sweetened foods and the risk of pancreatic cancer in a prospective study
-
Larsson, S.C., L. Bergkvist & A. Wolk 2006. Consumption of sugar and sugar-sweetened foods and the risk of pancreatic cancer in a prospective study. Am. J. Clin. Nutr. 84: 1171-1176.
-
(2006)
Am. J. Clin. Nutr.
, vol.84
, pp. 1171-1176
-
-
Larsson, S.C.1
Bergkvist, L.2
Wolk, A.3
-
34
-
-
21244485747
-
Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studies
-
Huxley, R., A. Ansary-Moghaddam, A. Berrington de Gonzalez, et al 2005. Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studies. Br. J. Cancer 92: 2076-2083.
-
(2005)
Br. J. Cancer
, vol.92
, pp. 2076-2083
-
-
Huxley, R.1
Ansary-Moghaddam, A.2
Berrington de Gonzalez, A.3
-
35
-
-
0032934505
-
The role of diabetes mellitus in the aetiology of renal cell cancer
-
Lindblad, P., W.H. Chow, J. Chan, et al 1999. The role of diabetes mellitus in the aetiology of renal cell cancer. Diabetologia 42: 107-112.
-
(1999)
Diabetologia
, vol.42
, pp. 107-112
-
-
Lindblad, P.1
Chow, W.H.2
Chan, J.3
-
36
-
-
33847722954
-
Diabetes and risk of endometrial cancer: a population-based prospective cohort study
-
Friberg, E., C.S. Mantzoros, & A. Wolk 2007. Diabetes and risk of endometrial cancer: a population-based prospective cohort study. Cancer Epidemiol. Biomarkers Prev. 16: 276-280.
-
(2007)
Cancer Epidemiol. Biomarkers Prev.
, vol.16
, pp. 276-280
-
-
Friberg, E.1
Mantzoros, C.S.2
Wolk, A.3
-
37
-
-
0029970843
-
Nutrition, hormones, and breast cancer: is insulin the missing link?
-
Kaaks, R. 1996. Nutrition, hormones, and breast cancer: is insulin the missing link? Cancer Causes Control 7: 605-625.
-
(1996)
Cancer Causes Control
, vol.7
, pp. 605-625
-
-
Kaaks, R.1
-
38
-
-
0032995207
-
Premalignant breast lesions: role for biological markers in predicting progression to cancer
-
Stoll, B.A. 1999. Premalignant breast lesions: role for biological markers in predicting progression to cancer. Eur. J. Cancer 35: 693-697.
-
(1999)
Eur. J. Cancer
, vol.35
, pp. 693-697
-
-
Stoll, B.A.1
-
39
-
-
47349129465
-
Obesity and cancer: pathophysiological and biological mechanisms
-
Renehan, A.G., D.L. Roberts & C. Dive 2008. Obesity and cancer: pathophysiological and biological mechanisms. Arch. Physiol. Biochem. 114: 71-83.
-
(2008)
Arch. Physiol. Biochem.
, vol.114
, pp. 71-83
-
-
Renehan, A.G.1
Roberts, D.L.2
Dive, C.3
-
40
-
-
0038398622
-
The insulin-like growth factor system and cancer
-
LeRoith, D. & C.T. Roberts 2003. The insulin-like growth factor system and cancer. Cancer Lett. 195: 127-137.
-
(2003)
Cancer Lett.
, vol.195
, pp. 127-137
-
-
LeRoith, D.1
Roberts, C.T.2
-
41
-
-
4444237280
-
Obesity and cancer
-
Calle, E.E. & M.J. Thun 2004. Obesity and cancer. Oncogene 23: 6365-6378.
-
(2004)
Oncogene
, vol.23
, pp. 6365-6378
-
-
Calle, E.E.1
Thun, M.J.2
-
42
-
-
4444284454
-
Free insulin-like growth factors - measurements and relationships to growth hormone secretion and glucose homeostasis
-
Frystyk, J. 2004. Free insulin-like growth factors - measurements and relationships to growth hormone secretion and glucose homeostasis. Growth Horm. IGF Res. 14: 337-375.
-
(2004)
Growth Horm. IGF Res.
, vol.14
, pp. 337-375
-
-
Frystyk, J.1
-
43
-
-
0032540667
-
Insulin-like growth factor 1 and prostate cancer risk: a population-based, case-control study
-
Wolk, A., C.S. Mantzoros, S.O. Andersson, et al 1998. Insulin-like growth factor 1 and prostate cancer risk: a population-based, case-control study. J. Natl. Cancer Inst. 90: 911-915.
-
(1998)
J. Natl. Cancer Inst.
, vol.90
, pp. 911-915
-
-
Wolk, A.1
Mantzoros, C.S.2
Andersson, S.O.3
-
44
-
-
0000820311
-
Serum insulin-like growth factor-1 is not a useful marker of prostate cancer
-
Cutting, C.W., C. Hunt, J.A. Nisbet, et al 1999. Serum insulin-like growth factor-1 is not a useful marker of prostate cancer. BJU Int. 83: 996-999.
-
(1999)
BJU Int.
, vol.83
, pp. 996-999
-
-
Cutting, C.W.1
Hunt, C.2
Nisbet, J.A.3
-
45
-
-
0032499440
-
Circulating concentrations of insulin-like growth factor-I and risk of breast cancer
-
Hankinson, S.E., W.C. Willett, G.A. Colditz, et al 1998. Circulating concentrations of insulin-like growth factor-I and risk of breast cancer. Lancet 351: 1393-1396.
-
(1998)
Lancet
, vol.351
, pp. 1393-1396
-
-
Hankinson, S.E.1
Willett, W.C.2
Colditz, G.A.3
-
46
-
-
0033531765
-
Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3
-
Ma, J., M.N. Pollak, E. Giovannucci, et al 1999. Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3. J. Natl. Cancer Inst. 91: 620-625.
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 620-625
-
-
Ma, J.1
Pollak, M.N.2
Giovannucci, E.3
-
47
-
-
57149100169
-
Bidirectional crosstalk between leptin and insulin-like growth factor-I signaling promotes invasion and migration of breast cancer cells via transactivation of epidermal growth factor receptor
-
Saxena, N.K., L. Taliaferro-Smith, B.B. Knight, et al 2008. Bidirectional crosstalk between leptin and insulin-like growth factor-I signaling promotes invasion and migration of breast cancer cells via transactivation of epidermal growth factor receptor. Cancer Res. 68: 9712-9722.
-
(2008)
Cancer Res.
, vol.68
, pp. 9712-9722
-
-
Saxena, N.K.1
Taliaferro-Smith, L.2
Knight, B.B.3
-
48
-
-
73349105273
-
Genetic reduction of circulating insulin-like growth factor-1 inhibits azoxymethane-induced colon tumorigenesis in mice
-
Olivo-Marston, S.E., S.D. Hursting, J. Lavigne, et al 2009. Genetic reduction of circulating insulin-like growth factor-1 inhibits azoxymethane-induced colon tumorigenesis in mice. Mol. Carcinog. 48: 1071-1076.
-
(2009)
Mol. Carcinog.
, vol.48
, pp. 1071-1076
-
-
Olivo-Marston, S.E.1
Hursting, S.D.2
Lavigne, J.3
-
49
-
-
74049092809
-
Calories and carcinogenesis: lessons learned from 30 years of calorie restriction research
-
Hursting, S.D., S.M. Smith, L.M. Lashinger 2010. Calories and carcinogenesis: lessons learned from 30 years of calorie restriction research. Carcinogenesis 31: 83-89.
-
(2010)
Carcinogenesis
, vol.31
, pp. 83-89
-
-
Hursting, S.D.1
Smith, S.M.2
Lashinger, L.M.3
-
50
-
-
33748615450
-
Inhibition of inflammatory response in transgenic fat-1 mice on a calorie-restricted diet
-
Bhattacharya, A., B. Chandrasekar, M.M. Rahman, et al 2006. Inhibition of inflammatory response in transgenic fat-1 mice on a calorie-restricted diet. Biochem. Biophys. Res. Commun. 349: 925-930.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.349
, pp. 925-930
-
-
Bhattacharya, A.1
Chandrasekar, B.2
Rahman, M.M.3
-
51
-
-
0038660699
-
Preadipocyte conversion to macrophage. Evidence of plasticity
-
Charriere, G., B. Cousin, E. Arnaud, et al 2003. Preadipocyte conversion to macrophage. Evidence of plasticity. J. Biol. Chem. 278: 9850-9855.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 9850-9855
-
-
Charriere, G.1
Cousin, B.2
Arnaud, E.3
-
52
-
-
60149088612
-
Inflammation in obesity-related diseases
-
O'Rourke, R.W. 2009. Inflammation in obesity-related diseases. Surgery 145: 255-259.
-
(2009)
Surgery
, vol.145
, pp. 255-259
-
-
O'Rourke, R.W.1
-
53
-
-
0036776903
-
Effect of rosiglitazone on insulin sensitivity and body composition in type 2 diabetic patients [corrected]
-
Carey, D.G., G.J. Cowin, G.J. Galloway, et al 2002. Effect of rosiglitazone on insulin sensitivity and body composition in type 2 diabetic patients [corrected]. Obes. Res. 10: 1008-1015.
-
(2002)
Obes. Res.
, vol.10
, pp. 1008-1015
-
-
Carey, D.G.1
Cowin, G.J.2
Galloway, G.J.3
-
54
-
-
79955862214
-
Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary gland
-
Subbaramaiah, K., L.R. Howe, P. Bhardwaj, et al 2011. Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary gland. Cancer Prev. Res. 4: 329-346.
-
(2011)
Cancer Prev. Res.
, vol.4
, pp. 329-346
-
-
Subbaramaiah, K.1
Howe, L.R.2
Bhardwaj, P.3
-
55
-
-
84880921729
-
IL-6 induction of TLR-4 gene expression via STAT3 has an effect on insulin resistance in human skeletal muscle
-
Kim, T., S. Choi, E. Ha, et al 2011. IL-6 induction of TLR-4 gene expression via STAT3 has an effect on insulin resistance in human skeletal muscle. Acta Diabetologica 1-12.
-
(2011)
Acta Diabetologica
, pp. 1-12
-
-
Kim, T.1
Choi, S.2
Ha, E.3
-
56
-
-
34047155003
-
Visceral fat adipokine secretion is associated with systemic inflammation in obese humans
-
Fontana, L., J.C. Eagon, M.E. Trujillo, et al 2007. Visceral fat adipokine secretion is associated with systemic inflammation in obese humans. Diabetes 56: 1010-1013.
-
(2007)
Diabetes
, vol.56
, pp. 1010-1013
-
-
Fontana, L.1
Eagon, J.C.2
Trujillo, M.E.3
-
57
-
-
33745686647
-
Interleukin-6 production induced by leptin treatment promotes cell proliferation in an Apc (Min/+) colon epithelial cell line
-
Fenton, J.I., S.D. Hursting, S.N. Perkins & N.G. Hord 2006. Interleukin-6 production induced by leptin treatment promotes cell proliferation in an Apc (Min/+) colon epithelial cell line. Carcinogenesis 27: 1507-1515.
-
(2006)
Carcinogenesis
, vol.27
, pp. 1507-1515
-
-
Fenton, J.I.1
Hursting, S.D.2
Perkins, S.N.3
Hord, N.G.4
-
59
-
-
1942469345
-
Leptin counteracts sodium butyrate-induced apoptosis in human colon cancer HT-29 cells via NF-kappaB signaling
-
Rouet-Benzineb, P., T. Aparicio, S. Guilmeau, et al 2004. Leptin counteracts sodium butyrate-induced apoptosis in human colon cancer HT-29 cells via NF-kappaB signaling. J. Biol. Chem. 279: 16495-16502.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 16495-16502
-
-
Rouet-Benzineb, P.1
Aparicio, T.2
Guilmeau, S.3
-
60
-
-
38049059990
-
The activation of NF-kappaB through Akt-induced FOXO1 phosphorylation during aging and its modulation by calorie restriction
-
Kim, D.H., J.Y. Kim, B.P. Yu & H.Y. Chung 2008. The activation of NF-kappaB through Akt-induced FOXO1 phosphorylation during aging and its modulation by calorie restriction. Biogerontology 9: 33-47.
-
(2008)
Biogerontology
, vol.9
, pp. 33-47
-
-
Kim, D.H.1
Kim, J.Y.2
Yu, B.P.3
Chung, H.Y.4
-
61
-
-
0037158513
-
Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications
-
Mitsiades, C.S., N. Mitsiades, V. Poulaki, et al 2002. Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications. Oncogene 21: 5673-5683.
-
(2002)
Oncogene
, vol.21
, pp. 5673-5683
-
-
Mitsiades, C.S.1
Mitsiades, N.2
Poulaki, V.3
-
64
-
-
0037180757
-
Inflammation and cancer
-
Coussens, L.M. & Z. Werb 2002. Inflammation and cancer. Nature 420: 860-867.
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
65
-
-
17644394616
-
Smoldering and polarized inflammation in the initiation and promotion of malignant disease
-
Balkwill, F., K.A. Charles & A. Mantovani 2005. Smoldering and polarized inflammation in the initiation and promotion of malignant disease. Cancer Cell. 7: 211-217.
-
(2005)
Cancer Cell.
, vol.7
, pp. 211-217
-
-
Balkwill, F.1
Charles, K.A.2
Mantovani, A.3
-
66
-
-
13444256288
-
Inflammation and cancer: the long reach of Ras
-
Karin, M. 2005. Inflammation and cancer: the long reach of Ras. Nature Med. 11: 20-21.
-
(2005)
Nature Med.
, vol.11
, pp. 20-21
-
-
Karin, M.1
-
67
-
-
33745298519
-
Nuclear factor-kappaB in cancer development and progression
-
Karin, M. 2006. Nuclear factor-kappaB in cancer development and progression. Nature 441: 431-436.
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
68
-
-
0034141680
-
Prognostic value of intratumoral natural killer cells in gastric carcinoma
-
Ishigami, S., S. Natsugoe, K. Tokuda, et al 2000. Prognostic value of intratumoral natural killer cells in gastric carcinoma. Cancer 88: 577-583.
-
(2000)
Cancer
, vol.88
, pp. 577-583
-
-
Ishigami, S.1
Natsugoe, S.2
Tokuda, K.3
-
69
-
-
0037569416
-
Tumor vascularity and tryptase-positive mast cells correlate with a poor prognosis in melanoma
-
Ribatti, D., M.G. Ennas, A. Vacca, et al 2003. Tumor vascularity and tryptase-positive mast cells correlate with a poor prognosis in melanoma. Eur. J. Clin. Invest. 33: 420-425.
-
(2003)
Eur. J. Clin. Invest.
, vol.33
, pp. 420-425
-
-
Ribatti, D.1
Ennas, M.G.2
Vacca, A.3
-
70
-
-
0033067163
-
Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast
-
Leek, R.D., R.J. Landers, A.L. Harris & C.E. Lewis 1999. Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast. Br. J. Cancer 79: 991-995.
-
(1999)
Br. J. Cancer
, vol.79
, pp. 991-995
-
-
Leek, R.D.1
Landers, R.J.2
Harris, A.L.3
Lewis, C.E.4
-
71
-
-
0037769717
-
Cyclooxygenase-2 in human pathological disease
-
Koki, A., N.K. Khan, B.M. Woerner, et al 2002. Cyclooxygenase-2 in human pathological disease. Adv. Exp. Med. Biol. 507: 177-184.
-
(2002)
Adv. Exp. Med. Biol.
, vol.507
, pp. 177-184
-
-
Koki, A.1
Khan, N.K.2
Woerner, B.M.3
-
72
-
-
33645739790
-
Tumor stroma and regulation of cancer development
-
Tlsty, T.D. & L.M. Coussens 2006. Tumor stroma and regulation of cancer development. Ann. Rev. Pathol. 1: 119-150.
-
(2006)
Ann. Rev. Pathol.
, vol.1
, pp. 119-150
-
-
Tlsty, T.D.1
Coussens, L.M.2
-
73
-
-
34248141100
-
A cytokine-mediated link between innate immunity, inflammation, and cancer
-
Lin, W.W. & M. Karin 2007. A cytokine-mediated link between innate immunity, inflammation, and cancer. J. Clin. Invest. 117: 1175-1183.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 1175-1183
-
-
Lin, W.W.1
Karin, M.2
-
74
-
-
6544233336
-
Interleukin-6 and soluble interleukin-6 receptor in the colonic mucosa of inflammatory bowel disease
-
Hosokawa, T., K. Kusugami, K. Ina, et al 1999. Interleukin-6 and soluble interleukin-6 receptor in the colonic mucosa of inflammatory bowel disease. J. Gastroenterol. Hepatol. 14: 987-996.
-
(1999)
J. Gastroenterol. Hepatol.
, vol.14
, pp. 987-996
-
-
Hosokawa, T.1
Kusugami, K.2
Ina, K.3
-
75
-
-
41149164902
-
The yin-yang of tumor-associated macrophages in neoplastic progression and immune surveillance
-
Allavena, P., A. Sica, C. Garlanda & A. Mantovani 2008. The yin-yang of tumor-associated macrophages in neoplastic progression and immune surveillance. Immunol. Rev. 222: 155-161.
-
(2008)
Immunol. Rev.
, vol.222
, pp. 155-161
-
-
Allavena, P.1
Sica, A.2
Garlanda, C.3
Mantovani, A.4
-
76
-
-
0036839143
-
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
-
Mantovani, A., S. Sozzani, M. Locati, et al 2002. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol. 23: 549-555.
-
(2002)
Trends Immunol.
, vol.23
, pp. 549-555
-
-
Mantovani, A.1
Sozzani, S.2
Locati, M.3
-
77
-
-
4043088499
-
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
-
Greten, F.R., L. Eckmann, T.F. Greten, et al 2004. IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 118: 285-296.
-
(2004)
Cell
, vol.118
, pp. 285-296
-
-
Greten, F.R.1
Eckmann, L.2
Greten, T.F.3
-
78
-
-
4644324186
-
NF-kappaB functions as a tumour promoter in inflammation-associated cancer
-
Pikarsky, E., R.M. Porat, I. Stein, et al 2004. NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature 431: 461-466.
-
(2004)
Nature
, vol.431
, pp. 461-466
-
-
Pikarsky, E.1
Porat, R.M.2
Stein, I.3
-
79
-
-
0035348486
-
Aspirin-induced activation of the NF-kappaB signaling pathway: a novel mechanism for aspirin-mediated apoptosis in colon cancer cells
-
Stark, L.A., F.V. Din, R.M. Zwacka & M.G. Dunlop 2001. Aspirin-induced activation of the NF-kappaB signaling pathway: a novel mechanism for aspirin-mediated apoptosis in colon cancer cells. FASEB J. 15: 1273-1275.
-
(2001)
FASEB J.
, vol.15
, pp. 1273-1275
-
-
Stark, L.A.1
Din, F.V.2
Zwacka, R.M.3
Dunlop, M.G.4
-
80
-
-
48249102773
-
-
Colby, J.K., R.D. Klein, M.J. McArthur, et al 2008. Neoplasia, N.Y. 10: 782-796.
-
(2008)
Neoplasia, N.Y.
, vol.10
, pp. 782-796
-
-
Colby, J.K.1
Klein, R.D.2
McArthur, M.J.3
-
81
-
-
9444296055
-
Cyclooxygenase-2-dependent and -independent effects of celecoxib in pancreatic cancer cell lines
-
El-Rayes, B.F., S. Ali, F.H. Sarkar & P.A. Philip 2004. Cyclooxygenase-2-dependent and -independent effects of celecoxib in pancreatic cancer cell lines. Mol. Cancer Ther. 3: 1421-1426.
-
(2004)
Mol. Cancer Ther.
, vol.3
, pp. 1421-1426
-
-
El-Rayes, B.F.1
Ali, S.2
Sarkar, F.H.3
Philip, P.A.4
-
82
-
-
37549027274
-
Cetuximab plus gemcitabine and cisplatin compared with gemcitabine and cisplatin alone in patients with advanced pancreatic cancer: a randomised, multicentre, phase II trial
-
Cascinu, S., R. Berardi, R. Labianca, et al 2008. Cetuximab plus gemcitabine and cisplatin compared with gemcitabine and cisplatin alone in patients with advanced pancreatic cancer: a randomised, multicentre, phase II trial. Lancet Oncol. 9: 39-44.
-
(2008)
Lancet Oncol.
, vol.9
, pp. 39-44
-
-
Cascinu, S.1
Berardi, R.2
Labianca, R.3
-
83
-
-
0033578879
-
Sulindac inhibits activation of the NF-kappaB pathway
-
Yamamoto, Y., M.J. Yin, K.M. Lin & R.B. Gaynor 1999. Sulindac inhibits activation of the NF-kappaB pathway. J. Biol. Chem. 274: 27307-27314.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 27307-27314
-
-
Yamamoto, Y.1
Yin, M.J.2
Lin, K.M.3
Gaynor, R.B.4
-
84
-
-
18044376489
-
Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-kappa B pathway in pancreatic carcinoma cells
-
Yip-Schneider, M.T., H. Nakshatri, C.J. Sweeney, et al 2005. Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-kappa B pathway in pancreatic carcinoma cells. Mol. Cancer Ther. 4: 587-594.
-
(2005)
Mol. Cancer Ther.
, vol.4
, pp. 587-594
-
-
Yip-Schneider, M.T.1
Nakshatri, H.2
Sweeney, C.J.3
-
85
-
-
0037342894
-
The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents
-
Ma, M.H., H.H. Yang, K. Parker, et al 2003. The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents. Clin. Cancer Res. 9: 1136-1144.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 1136-1144
-
-
Ma, M.H.1
Yang, H.H.2
Parker, K.3
-
86
-
-
23044479821
-
Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma
-
Shishodia, S., H.M. Amin, R. Lai & B.B. Aggarwal 2005. Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma. Biochem. Pharmacol. 70: 700-713.
-
(2005)
Biochem. Pharmacol.
, vol.70
, pp. 700-713
-
-
Shishodia, S.1
Amin, H.M.2
Lai, R.3
Aggarwal, B.B.4
-
87
-
-
46349088791
-
Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity
-
Weisberg, S.P., R. Leibel & D.V. Tortoriello 2008. Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity. Endocrinology 149: 3549-3558.
-
(2008)
Endocrinology
, vol.149
, pp. 3549-3558
-
-
Weisberg, S.P.1
Leibel, R.2
Tortoriello, D.V.3
-
88
-
-
0032763091
-
Curcumin inhibits cell proliferation by interfering with the cell cycle and inducing apoptosis in colon carcinoma cells
-
Chen, H., Z.S. Zhang, Y.L. Zhang & D.Y. Zhou 1999. Curcumin inhibits cell proliferation by interfering with the cell cycle and inducing apoptosis in colon carcinoma cells. Anticancer Res. 19: 3675-3680.
-
(1999)
Anticancer Res.
, vol.19
, pp. 3675-3680
-
-
Chen, H.1
Zhang, Z.S.2
Zhang, Y.L.3
Zhou, D.Y.4
-
89
-
-
7644223910
-
Nuclear factor-kappaB and IkappaB kinase are constitutively active in human pancreatic cells, and their down-regulation by curcumin (diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis
-
Li, L., B.B. Aggarwal, S. Shishodia, et al 2004. Nuclear factor-kappaB and IkappaB kinase are constitutively active in human pancreatic cells, and their down-regulation by curcumin (diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis. Cancer 101: 2351-2362.
-
(2004)
Cancer
, vol.101
, pp. 2351-2362
-
-
Li, L.1
Aggarwal, B.B.2
Shishodia, S.3
-
90
-
-
0030738229
-
Inhibitory effect of dietary curcumin on skin carcinogenesis in mice
-
Limtrakul, P., S. Lipigorngoson, O. Namwong, et al 1997. Inhibitory effect of dietary curcumin on skin carcinogenesis in mice. Cancer Lett. 116: 197-203.
-
(1997)
Cancer Lett.
, vol.116
, pp. 197-203
-
-
Limtrakul, P.1
Lipigorngoson, S.2
Namwong, O.3
-
91
-
-
0031313948
-
Inhibitory effects of curcumin on tumorigenesis in mice. Journal of cellular biochemistry
-
Huang, M.T., H.L. Newmark & K. Frenkel 1997. Inhibitory effects of curcumin on tumorigenesis in mice. Journal of cellular biochemistry. J. Cell. Biochem. 27: 26-34.
-
(1997)
J. Cell. Biochem.
, vol.27
, pp. 26-34
-
-
Huang, M.T.1
Newmark, H.L.2
Frenkel, K.3
-
92
-
-
0033801316
-
Inhibition by curcumin of diethylnitrosamine-induced hepatic hyperplasia, inflammation, cellular gene products and cell-cycle-related proteins in rats
-
Chuang, S.E., A.L. Cheng, J.K. Lin & M.L. Kuo 2000. Inhibition by curcumin of diethylnitrosamine-induced hepatic hyperplasia, inflammation, cellular gene products and cell-cycle-related proteins in rats. Food Chem. Toxicol. 38: 991-995.
-
(2000)
Food Chem. Toxicol.
, vol.38
, pp. 991-995
-
-
Chuang, S.E.1
Cheng, A.L.2
Lin, J.K.3
Kuo, M.L.4
-
93
-
-
0028867742
-
Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]
-
Singh, S. & B.B. Aggarwal 1995. Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]. J. Biol. Chem. 270: 24995-25000.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 24995-25000
-
-
Singh, S.1
Aggarwal, B.B.2
-
94
-
-
79954994405
-
Preparation and characterization of lyophilised EGG PC liposomes incorporating curcumin and evaluation of its activity against colorectal cancer cell lines
-
Pandelidou, M., K. Dimas, A. Georgopoulos, et al 2011. Preparation and characterization of lyophilised EGG PC liposomes incorporating curcumin and evaluation of its activity against colorectal cancer cell lines. J. Nanosci. Nanotechnol. 11: 1259-1266.
-
(2011)
J. Nanosci. Nanotechnol.
, vol.11
, pp. 1259-1266
-
-
Pandelidou, M.1
Dimas, K.2
Georgopoulos, A.3
|