메뉴 건너뛰기




Volumn 1229, Issue 1, 2011, Pages 45-52

The growing challenge of obesity and cancer: An inflammatory issue

Author keywords

Cancer; Growth factors; Hormones; Inflammation; Obesity

Indexed keywords

ACETYLSALICYLIC ACID; ADIPONECTIN; ANTINEOPLASTIC AGENT; BORTEZOMIB; CISPLATIN; CURCUMIN; CYCLOOXYGENASE 2 INHIBITOR; CYTOKINE; GEMCITABINE; GROWTH FACTOR; HORMONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LEPTIN; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; METFORMIN; MONOCYTE CHEMOTACTIC PROTEIN 1; NONSTEROID ANTIINFLAMMATORY AGENT; PARTHENOLIDE; PROTEIN INHIBITOR; RAPAMYCIN; RESVERATROL; SIRTUIN INHIBITOR; SOMATOMEDIN C; SULINDAC; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 79960820132     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2011.06096.x     Document Type: Article
Times cited : (222)

References (94)
  • 1
    • 2942554887 scopus 로고    scopus 로고
    • Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002
    • Hedley, A.A., C.L. Ogden, C.L. Johnson, et al 2004. Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002. JAMA 291: 2847-2850.
    • (2004) JAMA , vol.291 , pp. 2847-2850
    • Hedley, A.A.1    Ogden, C.L.2    Johnson, C.L.3
  • 2
    • 33846422032 scopus 로고    scopus 로고
    • Obesity and diabetes in the developing world - a growing challenge
    • Hossain, P., B. Kawar, & M. El Nahas 2007. Obesity and diabetes in the developing world - a growing challenge. N. Engl. J. Med. 356: 213-215.
    • (2007) N. Engl. J. Med. , vol.356 , pp. 213-215
    • Hossain, P.1    Kawar, B.2    El Nahas, M.3
  • 3
    • 0037464510 scopus 로고    scopus 로고
    • Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults
    • Calle, E.E., C. Rodriguez, K. Walker-Thurmond & M.J. Thun 2003. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N. Engl. J. Med. 348: 1625-1638.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 1625-1638
    • Calle, E.E.1    Rodriguez, C.2    Walker-Thurmond, K.3    Thun, M.J.4
  • 4
    • 33845544078 scopus 로고    scopus 로고
    • Relationship of metabolic risk factors and development of cardiovascular disease and diabetes
    • Haffner, S.M. 2006. Relationship of metabolic risk factors and development of cardiovascular disease and diabetes. Obesity 14(Suppl 3): 121S-127S.
    • (2006) Obesity , vol.14 , Issue.SUPPL. 3
    • Haffner, S.M.1
  • 5
    • 0028917432 scopus 로고
    • Weight gain as a risk factor for clinical diabetes mellitus in women
    • Colditz, G.A., W.C. Willett, A. Rotnitzky & J.E. Manson 1995. Weight gain as a risk factor for clinical diabetes mellitus in women. Ann. Int. Med. 122: 481-486.
    • (1995) Ann. Int. Med. , vol.122 , pp. 481-486
    • Colditz, G.A.1    Willett, W.C.2    Rotnitzky, A.3    Manson, J.E.4
  • 9
    • 0032572722 scopus 로고    scopus 로고
    • Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
    • Lord, G.M., G. Matarese, J.K. Howard, et al 1998. Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression. Nature 394: 897-901.
    • (1998) Nature , vol.394 , pp. 897-901
    • Lord, G.M.1    Matarese, G.2    Howard, J.K.3
  • 10
    • 0242329861 scopus 로고    scopus 로고
    • Leptin stimulates esophageal adenocarcinoma growth by nonapoptotic mechanisms
    • Somasundar, P., D. Riggs, B. Jackson, et al 2003. Leptin stimulates esophageal adenocarcinoma growth by nonapoptotic mechanisms. Am. J. Surg. 186: 575-578.
    • (2003) Am. J. Surg. , vol.186 , pp. 575-578
    • Somasundar, P.1    Riggs, D.2    Jackson, B.3
  • 11
    • 70350500225 scopus 로고    scopus 로고
    • STATs in cancer inflammation and immunity: a leading role for STAT3
    • Yu, H., D. Pardoll & R. Jove 2009. STATs in cancer inflammation and immunity: a leading role for STAT3. Nature Rev. 9: 798-809.
    • (2009) Nature Rev. , vol.9 , pp. 798-809
    • Yu, H.1    Pardoll, D.2    Jove, R.3
  • 14
    • 0035051194 scopus 로고    scopus 로고
    • Leptin is associated with increased prostate cancer risk: a nested case-referent study
    • Stattin, P., S. Soderberg, G. Hallmans, et al 2001. Leptin is associated with increased prostate cancer risk: a nested case-referent study. J. Clin. Endocrinol. Metab. 86: 1341-1345.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 1341-1345
    • Stattin, P.1    Soderberg, S.2    Hallmans, G.3
  • 15
    • 34547741589 scopus 로고    scopus 로고
    • Adipokines as endocrine, paracrine, and autocrine factors in breast cancer risk and progression
    • Vona-Davis, L. & D.P. Rose 2007. Adipokines as endocrine, paracrine, and autocrine factors in breast cancer risk and progression. Endocr.-Relat. Cancer 14: 189-206.
    • (2007) Endocr.-Relat. Cancer , vol.14 , pp. 189-206
    • Vona-Davis, L.1    Rose, D.P.2
  • 16
    • 0742277837 scopus 로고    scopus 로고
    • Plasma leptin and colorectal cancer risk: a prospective study in Northern Sweden
    • Stattin, P., R. Palmqvist, S. Soderberg, et al 2003. Plasma leptin and colorectal cancer risk: a prospective study in Northern Sweden. Oncol. Rep. 10: 2015-2021.
    • (2003) Oncol. Rep. , vol.10 , pp. 2015-2021
    • Stattin, P.1    Palmqvist, R.2    Soderberg, S.3
  • 17
    • 0742270445 scopus 로고    scopus 로고
    • Obesity and colon cancer: does leptin provide a link?
    • Stattin, P., A. Lukanova, C. Biessy, et al 2004. Obesity and colon cancer: does leptin provide a link? Int. J. Cancer 109: 149-152.
    • (2004) Int. J. Cancer , vol.109 , pp. 149-152
    • Stattin, P.1    Lukanova, A.2    Biessy, C.3
  • 19
    • 56049083633 scopus 로고    scopus 로고
    • Leptin promotes motility and invasiveness in human colon cancer cells by activating multiple signal-transduction pathways
    • Jaffe, T. & B. Schwartz 2008. Leptin promotes motility and invasiveness in human colon cancer cells by activating multiple signal-transduction pathways. Int. J. Cancer 123: 2543-2556.
    • (2008) Int. J. Cancer , vol.123 , pp. 2543-2556
    • Jaffe, T.1    Schwartz, B.2
  • 20
    • 0036177867 scopus 로고    scopus 로고
    • Control of energy homeostasis and insulin action by adipocyte hormones: leptin, acylation stimulating protein, and adiponectin
    • Havel, P.J. 2002. Control of energy homeostasis and insulin action by adipocyte hormones: leptin, acylation stimulating protein, and adiponectin. Curr. Opin. Lipidol. 13: 51-59.
    • (2002) Curr. Opin. Lipidol. , vol.13 , pp. 51-59
    • Havel, P.J.1
  • 21
    • 78249280002 scopus 로고    scopus 로고
    • Adiponectin and adiponectin receptor in relation to colorectal cancer progression
    • Byeon, J.-S., J.-Y. Jeong, M.J. Kim, et al 2010. Adiponectin and adiponectin receptor in relation to colorectal cancer progression. Int. J. Cancer 127: 2758-2767.
    • (2010) Int. J. Cancer , vol.127 , pp. 2758-2767
    • Byeon, J.-S.1    Jeong, J.-Y.2    Kim, M.J.3
  • 22
    • 56749116073 scopus 로고    scopus 로고
    • Serum adiponectin in relation to endometrial cancer and endometrial hyperplasia with atypia in obese women
    • Rzepka-Gorska, I., R. Bedner, A. Cymbaluk-Ploska & A. Chudecka-Glaz 2008. Serum adiponectin in relation to endometrial cancer and endometrial hyperplasia with atypia in obese women. Eur. J. Gynaecol. Oncol. 29: 594-597.
    • (2008) Eur. J. Gynaecol. Oncol. , vol.29 , pp. 594-597
    • Rzepka-Gorska, I.1    Bedner, R.2    Cymbaluk-Ploska, A.3    Chudecka-Glaz, A.4
  • 23
    • 35948957490 scopus 로고    scopus 로고
    • Anthropometric measures, plasma adiponectin, and breast cancer risk
    • Tian, Y.F., C.H. Chu, M.H. Wu, et al 2007. Anthropometric measures, plasma adiponectin, and breast cancer risk. Endocr.-Relat. Cancer 14: 669-677.
    • (2007) Endocr.-Relat. Cancer , vol.14 , pp. 669-677
    • Tian, Y.F.1    Chu, C.H.2    Wu, M.H.3
  • 24
    • 27944506001 scopus 로고    scopus 로고
    • Low plasma adiponectin levels and risk of colorectal cancer in men: a prospective study
    • Wei, E.K., E. Giovannucci, C.S. Fuchs, W.C. Willett & C.S. Mantzoros 2005. Low plasma adiponectin levels and risk of colorectal cancer in men: a prospective study. J. Natl. Cancer Inst. 97: 1688-1694.
    • (2005) J. Natl. Cancer Inst. , vol.97 , pp. 1688-1694
    • Wei, E.K.1    Giovannucci, E.2    Fuchs, C.S.3    Willett, W.C.4    Mantzoros, C.S.5
  • 25
    • 51649102135 scopus 로고    scopus 로고
    • Relationship between serum adiponectin and prostate cancer grade
    • Sher, D.J., W.K. Oh, S. Jacobus, et al 2008. Relationship between serum adiponectin and prostate cancer grade. Prostate 68: 1592-1598.
    • (2008) Prostate , vol.68 , pp. 1592-1598
    • Sher, D.J.1    Oh, W.K.2    Jacobus, S.3
  • 26
    • 40349108448 scopus 로고    scopus 로고
    • Adiponectin in relation to malignancies: a review of existing basic research and clinical evidence
    • Barb, D. et al Adiponectin in relation to malignancies: a review of existing basic research and clinical evidence. Am. J. Clin. Nutr. 86: 858S-866S.
    • Am. J. Clin. Nutr. , vol.86
    • Barb, D.1
  • 27
    • 71449120059 scopus 로고    scopus 로고
    • Insulin resistance and hyperinsulinaemia in the development and progression of cancer
    • Godsland, I.F. 2010. Insulin resistance and hyperinsulinaemia in the development and progression of cancer. Clin. Sci. 118: 315-332.
    • (2010) Clin. Sci. , vol.118 , pp. 315-332
    • Godsland, I.F.1
  • 28
    • 0033849777 scopus 로고    scopus 로고
    • Obesity and insulin resistance
    • Kahn, B.B. & J.S. Flier 2000. Obesity and insulin resistance. J. Clin. Invest. 106: 473-481.
    • (2000) J. Clin. Invest. , vol.106 , pp. 473-481
    • Kahn, B.B.1    Flier, J.S.2
  • 29
    • 47349117519 scopus 로고    scopus 로고
    • Hyper-insulinaemia and cancer, meta-analyses of epidemiological studies
    • Pisani, P. 2008. Hyper-insulinaemia and cancer, meta-analyses of epidemiological studies. Arch. Physiol. Biochem. 114: 63-70.
    • (2008) Arch. Physiol. Biochem. , vol.114 , pp. 63-70
    • Pisani, P.1
  • 30
    • 0141574296 scopus 로고    scopus 로고
    • Adipose tissue as an endocrine organ: impact on insulin resistance
    • Jazet, I.M., H. Pijl & A.E. Meinders 2003. Adipose tissue as an endocrine organ: impact on insulin resistance. Neth. J. Med. 61: 194-212.
    • (2003) Neth. J. Med. , vol.61 , pp. 194-212
    • Jazet, I.M.1    Pijl, H.2    Meinders, A.E.3
  • 31
    • 33845881411 scopus 로고    scopus 로고
    • Mechanisms linking obesity to insulin resistance and type 2 diabetes
    • Kahn, S.E., R.L. Hull & K.M. Utzschneider 2006. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 444: 840-846.
    • (2006) Nature , vol.444 , pp. 840-846
    • Kahn, S.E.1    Hull, R.L.2    Utzschneider, K.M.3
  • 33
    • 33750900938 scopus 로고    scopus 로고
    • Consumption of sugar and sugar-sweetened foods and the risk of pancreatic cancer in a prospective study
    • Larsson, S.C., L. Bergkvist & A. Wolk 2006. Consumption of sugar and sugar-sweetened foods and the risk of pancreatic cancer in a prospective study. Am. J. Clin. Nutr. 84: 1171-1176.
    • (2006) Am. J. Clin. Nutr. , vol.84 , pp. 1171-1176
    • Larsson, S.C.1    Bergkvist, L.2    Wolk, A.3
  • 34
    • 21244485747 scopus 로고    scopus 로고
    • Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studies
    • Huxley, R., A. Ansary-Moghaddam, A. Berrington de Gonzalez, et al 2005. Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studies. Br. J. Cancer 92: 2076-2083.
    • (2005) Br. J. Cancer , vol.92 , pp. 2076-2083
    • Huxley, R.1    Ansary-Moghaddam, A.2    Berrington de Gonzalez, A.3
  • 35
    • 0032934505 scopus 로고    scopus 로고
    • The role of diabetes mellitus in the aetiology of renal cell cancer
    • Lindblad, P., W.H. Chow, J. Chan, et al 1999. The role of diabetes mellitus in the aetiology of renal cell cancer. Diabetologia 42: 107-112.
    • (1999) Diabetologia , vol.42 , pp. 107-112
    • Lindblad, P.1    Chow, W.H.2    Chan, J.3
  • 36
    • 33847722954 scopus 로고    scopus 로고
    • Diabetes and risk of endometrial cancer: a population-based prospective cohort study
    • Friberg, E., C.S. Mantzoros, & A. Wolk 2007. Diabetes and risk of endometrial cancer: a population-based prospective cohort study. Cancer Epidemiol. Biomarkers Prev. 16: 276-280.
    • (2007) Cancer Epidemiol. Biomarkers Prev. , vol.16 , pp. 276-280
    • Friberg, E.1    Mantzoros, C.S.2    Wolk, A.3
  • 37
    • 0029970843 scopus 로고    scopus 로고
    • Nutrition, hormones, and breast cancer: is insulin the missing link?
    • Kaaks, R. 1996. Nutrition, hormones, and breast cancer: is insulin the missing link? Cancer Causes Control 7: 605-625.
    • (1996) Cancer Causes Control , vol.7 , pp. 605-625
    • Kaaks, R.1
  • 38
    • 0032995207 scopus 로고    scopus 로고
    • Premalignant breast lesions: role for biological markers in predicting progression to cancer
    • Stoll, B.A. 1999. Premalignant breast lesions: role for biological markers in predicting progression to cancer. Eur. J. Cancer 35: 693-697.
    • (1999) Eur. J. Cancer , vol.35 , pp. 693-697
    • Stoll, B.A.1
  • 39
    • 47349129465 scopus 로고    scopus 로고
    • Obesity and cancer: pathophysiological and biological mechanisms
    • Renehan, A.G., D.L. Roberts & C. Dive 2008. Obesity and cancer: pathophysiological and biological mechanisms. Arch. Physiol. Biochem. 114: 71-83.
    • (2008) Arch. Physiol. Biochem. , vol.114 , pp. 71-83
    • Renehan, A.G.1    Roberts, D.L.2    Dive, C.3
  • 40
    • 0038398622 scopus 로고    scopus 로고
    • The insulin-like growth factor system and cancer
    • LeRoith, D. & C.T. Roberts 2003. The insulin-like growth factor system and cancer. Cancer Lett. 195: 127-137.
    • (2003) Cancer Lett. , vol.195 , pp. 127-137
    • LeRoith, D.1    Roberts, C.T.2
  • 41
    • 4444237280 scopus 로고    scopus 로고
    • Obesity and cancer
    • Calle, E.E. & M.J. Thun 2004. Obesity and cancer. Oncogene 23: 6365-6378.
    • (2004) Oncogene , vol.23 , pp. 6365-6378
    • Calle, E.E.1    Thun, M.J.2
  • 42
    • 4444284454 scopus 로고    scopus 로고
    • Free insulin-like growth factors - measurements and relationships to growth hormone secretion and glucose homeostasis
    • Frystyk, J. 2004. Free insulin-like growth factors - measurements and relationships to growth hormone secretion and glucose homeostasis. Growth Horm. IGF Res. 14: 337-375.
    • (2004) Growth Horm. IGF Res. , vol.14 , pp. 337-375
    • Frystyk, J.1
  • 43
    • 0032540667 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 and prostate cancer risk: a population-based, case-control study
    • Wolk, A., C.S. Mantzoros, S.O. Andersson, et al 1998. Insulin-like growth factor 1 and prostate cancer risk: a population-based, case-control study. J. Natl. Cancer Inst. 90: 911-915.
    • (1998) J. Natl. Cancer Inst. , vol.90 , pp. 911-915
    • Wolk, A.1    Mantzoros, C.S.2    Andersson, S.O.3
  • 44
    • 0000820311 scopus 로고    scopus 로고
    • Serum insulin-like growth factor-1 is not a useful marker of prostate cancer
    • Cutting, C.W., C. Hunt, J.A. Nisbet, et al 1999. Serum insulin-like growth factor-1 is not a useful marker of prostate cancer. BJU Int. 83: 996-999.
    • (1999) BJU Int. , vol.83 , pp. 996-999
    • Cutting, C.W.1    Hunt, C.2    Nisbet, J.A.3
  • 45
    • 0032499440 scopus 로고    scopus 로고
    • Circulating concentrations of insulin-like growth factor-I and risk of breast cancer
    • Hankinson, S.E., W.C. Willett, G.A. Colditz, et al 1998. Circulating concentrations of insulin-like growth factor-I and risk of breast cancer. Lancet 351: 1393-1396.
    • (1998) Lancet , vol.351 , pp. 1393-1396
    • Hankinson, S.E.1    Willett, W.C.2    Colditz, G.A.3
  • 46
    • 0033531765 scopus 로고    scopus 로고
    • Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3
    • Ma, J., M.N. Pollak, E. Giovannucci, et al 1999. Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3. J. Natl. Cancer Inst. 91: 620-625.
    • (1999) J. Natl. Cancer Inst. , vol.91 , pp. 620-625
    • Ma, J.1    Pollak, M.N.2    Giovannucci, E.3
  • 47
    • 57149100169 scopus 로고    scopus 로고
    • Bidirectional crosstalk between leptin and insulin-like growth factor-I signaling promotes invasion and migration of breast cancer cells via transactivation of epidermal growth factor receptor
    • Saxena, N.K., L. Taliaferro-Smith, B.B. Knight, et al 2008. Bidirectional crosstalk between leptin and insulin-like growth factor-I signaling promotes invasion and migration of breast cancer cells via transactivation of epidermal growth factor receptor. Cancer Res. 68: 9712-9722.
    • (2008) Cancer Res. , vol.68 , pp. 9712-9722
    • Saxena, N.K.1    Taliaferro-Smith, L.2    Knight, B.B.3
  • 48
    • 73349105273 scopus 로고    scopus 로고
    • Genetic reduction of circulating insulin-like growth factor-1 inhibits azoxymethane-induced colon tumorigenesis in mice
    • Olivo-Marston, S.E., S.D. Hursting, J. Lavigne, et al 2009. Genetic reduction of circulating insulin-like growth factor-1 inhibits azoxymethane-induced colon tumorigenesis in mice. Mol. Carcinog. 48: 1071-1076.
    • (2009) Mol. Carcinog. , vol.48 , pp. 1071-1076
    • Olivo-Marston, S.E.1    Hursting, S.D.2    Lavigne, J.3
  • 49
    • 74049092809 scopus 로고    scopus 로고
    • Calories and carcinogenesis: lessons learned from 30 years of calorie restriction research
    • Hursting, S.D., S.M. Smith, L.M. Lashinger 2010. Calories and carcinogenesis: lessons learned from 30 years of calorie restriction research. Carcinogenesis 31: 83-89.
    • (2010) Carcinogenesis , vol.31 , pp. 83-89
    • Hursting, S.D.1    Smith, S.M.2    Lashinger, L.M.3
  • 50
    • 33748615450 scopus 로고    scopus 로고
    • Inhibition of inflammatory response in transgenic fat-1 mice on a calorie-restricted diet
    • Bhattacharya, A., B. Chandrasekar, M.M. Rahman, et al 2006. Inhibition of inflammatory response in transgenic fat-1 mice on a calorie-restricted diet. Biochem. Biophys. Res. Commun. 349: 925-930.
    • (2006) Biochem. Biophys. Res. Commun. , vol.349 , pp. 925-930
    • Bhattacharya, A.1    Chandrasekar, B.2    Rahman, M.M.3
  • 51
    • 0038660699 scopus 로고    scopus 로고
    • Preadipocyte conversion to macrophage. Evidence of plasticity
    • Charriere, G., B. Cousin, E. Arnaud, et al 2003. Preadipocyte conversion to macrophage. Evidence of plasticity. J. Biol. Chem. 278: 9850-9855.
    • (2003) J. Biol. Chem. , vol.278 , pp. 9850-9855
    • Charriere, G.1    Cousin, B.2    Arnaud, E.3
  • 52
    • 60149088612 scopus 로고    scopus 로고
    • Inflammation in obesity-related diseases
    • O'Rourke, R.W. 2009. Inflammation in obesity-related diseases. Surgery 145: 255-259.
    • (2009) Surgery , vol.145 , pp. 255-259
    • O'Rourke, R.W.1
  • 53
    • 0036776903 scopus 로고    scopus 로고
    • Effect of rosiglitazone on insulin sensitivity and body composition in type 2 diabetic patients [corrected]
    • Carey, D.G., G.J. Cowin, G.J. Galloway, et al 2002. Effect of rosiglitazone on insulin sensitivity and body composition in type 2 diabetic patients [corrected]. Obes. Res. 10: 1008-1015.
    • (2002) Obes. Res. , vol.10 , pp. 1008-1015
    • Carey, D.G.1    Cowin, G.J.2    Galloway, G.J.3
  • 54
    • 79955862214 scopus 로고    scopus 로고
    • Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary gland
    • Subbaramaiah, K., L.R. Howe, P. Bhardwaj, et al 2011. Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary gland. Cancer Prev. Res. 4: 329-346.
    • (2011) Cancer Prev. Res. , vol.4 , pp. 329-346
    • Subbaramaiah, K.1    Howe, L.R.2    Bhardwaj, P.3
  • 55
    • 84880921729 scopus 로고    scopus 로고
    • IL-6 induction of TLR-4 gene expression via STAT3 has an effect on insulin resistance in human skeletal muscle
    • Kim, T., S. Choi, E. Ha, et al 2011. IL-6 induction of TLR-4 gene expression via STAT3 has an effect on insulin resistance in human skeletal muscle. Acta Diabetologica 1-12.
    • (2011) Acta Diabetologica , pp. 1-12
    • Kim, T.1    Choi, S.2    Ha, E.3
  • 56
    • 34047155003 scopus 로고    scopus 로고
    • Visceral fat adipokine secretion is associated with systemic inflammation in obese humans
    • Fontana, L., J.C. Eagon, M.E. Trujillo, et al 2007. Visceral fat adipokine secretion is associated with systemic inflammation in obese humans. Diabetes 56: 1010-1013.
    • (2007) Diabetes , vol.56 , pp. 1010-1013
    • Fontana, L.1    Eagon, J.C.2    Trujillo, M.E.3
  • 57
    • 33745686647 scopus 로고    scopus 로고
    • Interleukin-6 production induced by leptin treatment promotes cell proliferation in an Apc (Min/+) colon epithelial cell line
    • Fenton, J.I., S.D. Hursting, S.N. Perkins & N.G. Hord 2006. Interleukin-6 production induced by leptin treatment promotes cell proliferation in an Apc (Min/+) colon epithelial cell line. Carcinogenesis 27: 1507-1515.
    • (2006) Carcinogenesis , vol.27 , pp. 1507-1515
    • Fenton, J.I.1    Hursting, S.D.2    Perkins, S.N.3    Hord, N.G.4
  • 59
    • 1942469345 scopus 로고    scopus 로고
    • Leptin counteracts sodium butyrate-induced apoptosis in human colon cancer HT-29 cells via NF-kappaB signaling
    • Rouet-Benzineb, P., T. Aparicio, S. Guilmeau, et al 2004. Leptin counteracts sodium butyrate-induced apoptosis in human colon cancer HT-29 cells via NF-kappaB signaling. J. Biol. Chem. 279: 16495-16502.
    • (2004) J. Biol. Chem. , vol.279 , pp. 16495-16502
    • Rouet-Benzineb, P.1    Aparicio, T.2    Guilmeau, S.3
  • 60
    • 38049059990 scopus 로고    scopus 로고
    • The activation of NF-kappaB through Akt-induced FOXO1 phosphorylation during aging and its modulation by calorie restriction
    • Kim, D.H., J.Y. Kim, B.P. Yu & H.Y. Chung 2008. The activation of NF-kappaB through Akt-induced FOXO1 phosphorylation during aging and its modulation by calorie restriction. Biogerontology 9: 33-47.
    • (2008) Biogerontology , vol.9 , pp. 33-47
    • Kim, D.H.1    Kim, J.Y.2    Yu, B.P.3    Chung, H.Y.4
  • 61
    • 0037158513 scopus 로고    scopus 로고
    • Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications
    • Mitsiades, C.S., N. Mitsiades, V. Poulaki, et al 2002. Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications. Oncogene 21: 5673-5683.
    • (2002) Oncogene , vol.21 , pp. 5673-5683
    • Mitsiades, C.S.1    Mitsiades, N.2    Poulaki, V.3
  • 64
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens, L.M. & Z. Werb 2002. Inflammation and cancer. Nature 420: 860-867.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 65
    • 17644394616 scopus 로고    scopus 로고
    • Smoldering and polarized inflammation in the initiation and promotion of malignant disease
    • Balkwill, F., K.A. Charles & A. Mantovani 2005. Smoldering and polarized inflammation in the initiation and promotion of malignant disease. Cancer Cell. 7: 211-217.
    • (2005) Cancer Cell. , vol.7 , pp. 211-217
    • Balkwill, F.1    Charles, K.A.2    Mantovani, A.3
  • 66
    • 13444256288 scopus 로고    scopus 로고
    • Inflammation and cancer: the long reach of Ras
    • Karin, M. 2005. Inflammation and cancer: the long reach of Ras. Nature Med. 11: 20-21.
    • (2005) Nature Med. , vol.11 , pp. 20-21
    • Karin, M.1
  • 67
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-kappaB in cancer development and progression
    • Karin, M. 2006. Nuclear factor-kappaB in cancer development and progression. Nature 441: 431-436.
    • (2006) Nature , vol.441 , pp. 431-436
    • Karin, M.1
  • 68
    • 0034141680 scopus 로고    scopus 로고
    • Prognostic value of intratumoral natural killer cells in gastric carcinoma
    • Ishigami, S., S. Natsugoe, K. Tokuda, et al 2000. Prognostic value of intratumoral natural killer cells in gastric carcinoma. Cancer 88: 577-583.
    • (2000) Cancer , vol.88 , pp. 577-583
    • Ishigami, S.1    Natsugoe, S.2    Tokuda, K.3
  • 69
    • 0037569416 scopus 로고    scopus 로고
    • Tumor vascularity and tryptase-positive mast cells correlate with a poor prognosis in melanoma
    • Ribatti, D., M.G. Ennas, A. Vacca, et al 2003. Tumor vascularity and tryptase-positive mast cells correlate with a poor prognosis in melanoma. Eur. J. Clin. Invest. 33: 420-425.
    • (2003) Eur. J. Clin. Invest. , vol.33 , pp. 420-425
    • Ribatti, D.1    Ennas, M.G.2    Vacca, A.3
  • 70
    • 0033067163 scopus 로고    scopus 로고
    • Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast
    • Leek, R.D., R.J. Landers, A.L. Harris & C.E. Lewis 1999. Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast. Br. J. Cancer 79: 991-995.
    • (1999) Br. J. Cancer , vol.79 , pp. 991-995
    • Leek, R.D.1    Landers, R.J.2    Harris, A.L.3    Lewis, C.E.4
  • 71
    • 0037769717 scopus 로고    scopus 로고
    • Cyclooxygenase-2 in human pathological disease
    • Koki, A., N.K. Khan, B.M. Woerner, et al 2002. Cyclooxygenase-2 in human pathological disease. Adv. Exp. Med. Biol. 507: 177-184.
    • (2002) Adv. Exp. Med. Biol. , vol.507 , pp. 177-184
    • Koki, A.1    Khan, N.K.2    Woerner, B.M.3
  • 72
    • 33645739790 scopus 로고    scopus 로고
    • Tumor stroma and regulation of cancer development
    • Tlsty, T.D. & L.M. Coussens 2006. Tumor stroma and regulation of cancer development. Ann. Rev. Pathol. 1: 119-150.
    • (2006) Ann. Rev. Pathol. , vol.1 , pp. 119-150
    • Tlsty, T.D.1    Coussens, L.M.2
  • 73
    • 34248141100 scopus 로고    scopus 로고
    • A cytokine-mediated link between innate immunity, inflammation, and cancer
    • Lin, W.W. & M. Karin 2007. A cytokine-mediated link between innate immunity, inflammation, and cancer. J. Clin. Invest. 117: 1175-1183.
    • (2007) J. Clin. Invest. , vol.117 , pp. 1175-1183
    • Lin, W.W.1    Karin, M.2
  • 74
    • 6544233336 scopus 로고    scopus 로고
    • Interleukin-6 and soluble interleukin-6 receptor in the colonic mucosa of inflammatory bowel disease
    • Hosokawa, T., K. Kusugami, K. Ina, et al 1999. Interleukin-6 and soluble interleukin-6 receptor in the colonic mucosa of inflammatory bowel disease. J. Gastroenterol. Hepatol. 14: 987-996.
    • (1999) J. Gastroenterol. Hepatol. , vol.14 , pp. 987-996
    • Hosokawa, T.1    Kusugami, K.2    Ina, K.3
  • 75
    • 41149164902 scopus 로고    scopus 로고
    • The yin-yang of tumor-associated macrophages in neoplastic progression and immune surveillance
    • Allavena, P., A. Sica, C. Garlanda & A. Mantovani 2008. The yin-yang of tumor-associated macrophages in neoplastic progression and immune surveillance. Immunol. Rev. 222: 155-161.
    • (2008) Immunol. Rev. , vol.222 , pp. 155-161
    • Allavena, P.1    Sica, A.2    Garlanda, C.3    Mantovani, A.4
  • 76
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • Mantovani, A., S. Sozzani, M. Locati, et al 2002. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol. 23: 549-555.
    • (2002) Trends Immunol. , vol.23 , pp. 549-555
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3
  • 77
    • 4043088499 scopus 로고    scopus 로고
    • IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
    • Greten, F.R., L. Eckmann, T.F. Greten, et al 2004. IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 118: 285-296.
    • (2004) Cell , vol.118 , pp. 285-296
    • Greten, F.R.1    Eckmann, L.2    Greten, T.F.3
  • 78
    • 4644324186 scopus 로고    scopus 로고
    • NF-kappaB functions as a tumour promoter in inflammation-associated cancer
    • Pikarsky, E., R.M. Porat, I. Stein, et al 2004. NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature 431: 461-466.
    • (2004) Nature , vol.431 , pp. 461-466
    • Pikarsky, E.1    Porat, R.M.2    Stein, I.3
  • 79
    • 0035348486 scopus 로고    scopus 로고
    • Aspirin-induced activation of the NF-kappaB signaling pathway: a novel mechanism for aspirin-mediated apoptosis in colon cancer cells
    • Stark, L.A., F.V. Din, R.M. Zwacka & M.G. Dunlop 2001. Aspirin-induced activation of the NF-kappaB signaling pathway: a novel mechanism for aspirin-mediated apoptosis in colon cancer cells. FASEB J. 15: 1273-1275.
    • (2001) FASEB J. , vol.15 , pp. 1273-1275
    • Stark, L.A.1    Din, F.V.2    Zwacka, R.M.3    Dunlop, M.G.4
  • 81
    • 9444296055 scopus 로고    scopus 로고
    • Cyclooxygenase-2-dependent and -independent effects of celecoxib in pancreatic cancer cell lines
    • El-Rayes, B.F., S. Ali, F.H. Sarkar & P.A. Philip 2004. Cyclooxygenase-2-dependent and -independent effects of celecoxib in pancreatic cancer cell lines. Mol. Cancer Ther. 3: 1421-1426.
    • (2004) Mol. Cancer Ther. , vol.3 , pp. 1421-1426
    • El-Rayes, B.F.1    Ali, S.2    Sarkar, F.H.3    Philip, P.A.4
  • 82
    • 37549027274 scopus 로고    scopus 로고
    • Cetuximab plus gemcitabine and cisplatin compared with gemcitabine and cisplatin alone in patients with advanced pancreatic cancer: a randomised, multicentre, phase II trial
    • Cascinu, S., R. Berardi, R. Labianca, et al 2008. Cetuximab plus gemcitabine and cisplatin compared with gemcitabine and cisplatin alone in patients with advanced pancreatic cancer: a randomised, multicentre, phase II trial. Lancet Oncol. 9: 39-44.
    • (2008) Lancet Oncol. , vol.9 , pp. 39-44
    • Cascinu, S.1    Berardi, R.2    Labianca, R.3
  • 83
    • 0033578879 scopus 로고    scopus 로고
    • Sulindac inhibits activation of the NF-kappaB pathway
    • Yamamoto, Y., M.J. Yin, K.M. Lin & R.B. Gaynor 1999. Sulindac inhibits activation of the NF-kappaB pathway. J. Biol. Chem. 274: 27307-27314.
    • (1999) J. Biol. Chem. , vol.274 , pp. 27307-27314
    • Yamamoto, Y.1    Yin, M.J.2    Lin, K.M.3    Gaynor, R.B.4
  • 84
    • 18044376489 scopus 로고    scopus 로고
    • Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-kappa B pathway in pancreatic carcinoma cells
    • Yip-Schneider, M.T., H. Nakshatri, C.J. Sweeney, et al 2005. Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-kappa B pathway in pancreatic carcinoma cells. Mol. Cancer Ther. 4: 587-594.
    • (2005) Mol. Cancer Ther. , vol.4 , pp. 587-594
    • Yip-Schneider, M.T.1    Nakshatri, H.2    Sweeney, C.J.3
  • 85
    • 0037342894 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents
    • Ma, M.H., H.H. Yang, K. Parker, et al 2003. The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents. Clin. Cancer Res. 9: 1136-1144.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 1136-1144
    • Ma, M.H.1    Yang, H.H.2    Parker, K.3
  • 86
    • 23044479821 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma
    • Shishodia, S., H.M. Amin, R. Lai & B.B. Aggarwal 2005. Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma. Biochem. Pharmacol. 70: 700-713.
    • (2005) Biochem. Pharmacol. , vol.70 , pp. 700-713
    • Shishodia, S.1    Amin, H.M.2    Lai, R.3    Aggarwal, B.B.4
  • 87
    • 46349088791 scopus 로고    scopus 로고
    • Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity
    • Weisberg, S.P., R. Leibel & D.V. Tortoriello 2008. Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity. Endocrinology 149: 3549-3558.
    • (2008) Endocrinology , vol.149 , pp. 3549-3558
    • Weisberg, S.P.1    Leibel, R.2    Tortoriello, D.V.3
  • 88
    • 0032763091 scopus 로고    scopus 로고
    • Curcumin inhibits cell proliferation by interfering with the cell cycle and inducing apoptosis in colon carcinoma cells
    • Chen, H., Z.S. Zhang, Y.L. Zhang & D.Y. Zhou 1999. Curcumin inhibits cell proliferation by interfering with the cell cycle and inducing apoptosis in colon carcinoma cells. Anticancer Res. 19: 3675-3680.
    • (1999) Anticancer Res. , vol.19 , pp. 3675-3680
    • Chen, H.1    Zhang, Z.S.2    Zhang, Y.L.3    Zhou, D.Y.4
  • 89
    • 7644223910 scopus 로고    scopus 로고
    • Nuclear factor-kappaB and IkappaB kinase are constitutively active in human pancreatic cells, and their down-regulation by curcumin (diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis
    • Li, L., B.B. Aggarwal, S. Shishodia, et al 2004. Nuclear factor-kappaB and IkappaB kinase are constitutively active in human pancreatic cells, and their down-regulation by curcumin (diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis. Cancer 101: 2351-2362.
    • (2004) Cancer , vol.101 , pp. 2351-2362
    • Li, L.1    Aggarwal, B.B.2    Shishodia, S.3
  • 90
    • 0030738229 scopus 로고    scopus 로고
    • Inhibitory effect of dietary curcumin on skin carcinogenesis in mice
    • Limtrakul, P., S. Lipigorngoson, O. Namwong, et al 1997. Inhibitory effect of dietary curcumin on skin carcinogenesis in mice. Cancer Lett. 116: 197-203.
    • (1997) Cancer Lett. , vol.116 , pp. 197-203
    • Limtrakul, P.1    Lipigorngoson, S.2    Namwong, O.3
  • 91
    • 0031313948 scopus 로고    scopus 로고
    • Inhibitory effects of curcumin on tumorigenesis in mice. Journal of cellular biochemistry
    • Huang, M.T., H.L. Newmark & K. Frenkel 1997. Inhibitory effects of curcumin on tumorigenesis in mice. Journal of cellular biochemistry. J. Cell. Biochem. 27: 26-34.
    • (1997) J. Cell. Biochem. , vol.27 , pp. 26-34
    • Huang, M.T.1    Newmark, H.L.2    Frenkel, K.3
  • 92
    • 0033801316 scopus 로고    scopus 로고
    • Inhibition by curcumin of diethylnitrosamine-induced hepatic hyperplasia, inflammation, cellular gene products and cell-cycle-related proteins in rats
    • Chuang, S.E., A.L. Cheng, J.K. Lin & M.L. Kuo 2000. Inhibition by curcumin of diethylnitrosamine-induced hepatic hyperplasia, inflammation, cellular gene products and cell-cycle-related proteins in rats. Food Chem. Toxicol. 38: 991-995.
    • (2000) Food Chem. Toxicol. , vol.38 , pp. 991-995
    • Chuang, S.E.1    Cheng, A.L.2    Lin, J.K.3    Kuo, M.L.4
  • 93
    • 0028867742 scopus 로고
    • Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]
    • Singh, S. & B.B. Aggarwal 1995. Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]. J. Biol. Chem. 270: 24995-25000.
    • (1995) J. Biol. Chem. , vol.270 , pp. 24995-25000
    • Singh, S.1    Aggarwal, B.B.2
  • 94
    • 79954994405 scopus 로고    scopus 로고
    • Preparation and characterization of lyophilised EGG PC liposomes incorporating curcumin and evaluation of its activity against colorectal cancer cell lines
    • Pandelidou, M., K. Dimas, A. Georgopoulos, et al 2011. Preparation and characterization of lyophilised EGG PC liposomes incorporating curcumin and evaluation of its activity against colorectal cancer cell lines. J. Nanosci. Nanotechnol. 11: 1259-1266.
    • (2011) J. Nanosci. Nanotechnol. , vol.11 , pp. 1259-1266
    • Pandelidou, M.1    Dimas, K.2    Georgopoulos, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.