메뉴 건너뛰기




Volumn 8, Issue 8, 2009, Pages 2110-2121

Molecular predictors of response to a humanized anti-insulin-like growth factor-I receptor monoclonal antibody in breast and colorectal cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANTIESTROGEN; BIOLOGICAL MARKER; ESTROGEN RECEPTOR; HUMANIZED INSULIN LIKE GROWTH FACTOR 1 RECEPTOR MONOCLONAL ANTIBODY; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; MONOCLONAL ANTIBODY; RECEPTOR ANTIBODY; SOMATOMEDIN B; SOMATOMEDIN C RECEPTOR; TAMOXIFEN; UNCLASSIFIED DRUG;

EID: 68849128275     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-09-0381     Document Type: Article
Times cited : (80)

References (45)
  • 1
    • 0028863148 scopus 로고
    • The role of the tyrosine kinase domain of the insulin-like growth factor-I receptor in intracellular signaling, cellular proliferation, and tumorigenesis
    • Hernandez-Sanchez C, Blakesley V, Kalebic T, Helman L, LeRoith D. The role of the tyrosine kinase domain of the insulin-like growth factor-I receptor in intracellular signaling, cellular proliferation, and tumorigenesis. J Biol Chem 1995;270:29176-81.
    • (1995) J Biol Chem , vol.270 , pp. 29176-29181
    • Hernandez-Sanchez, C.1    Blakesley, V.2    Kalebic, T.3    Helman, L.4    LeRoith, D.5
  • 3
    • 0033838566 scopus 로고    scopus 로고
    • Function of the IGF-I receptor in breast cancer
    • Surmacz E. Function of the IGF-I receptor in breast cancer. J Mammary Gland Biol Neoplasia 2000;5:95-105.
    • (2000) J Mammary Gland Biol Neoplasia , vol.5 , pp. 95-105
    • Surmacz, E.1
  • 4
    • 0036111682 scopus 로고    scopus 로고
    • Insulin-like growth factors and cancer
    • Furstenberger G, Senn HJ. Insulin-like growth factors and cancer. Lancet Oncol 2002;3:298-302.
    • (2002) Lancet Oncol , vol.3 , pp. 298-302
    • Furstenberger, G.1    Senn, H.J.2
  • 5
    • 0037436509 scopus 로고    scopus 로고
    • Cui H, Cruz-Correa M, Giardiello FM, et al. Loss of IGF2 imprinting: a potential marker of colorectal cancer risk. Science (New York, NY) 2003;299:1753-5.
    • Cui H, Cruz-Correa M, Giardiello FM, et al. Loss of IGF2 imprinting: a potential marker of colorectal cancer risk. Science (New York, NY) 2003;299:1753-5.
  • 6
    • 0033059976 scopus 로고    scopus 로고
    • Enhancement of susceptibility to diverse skin tumor promoters by activation of the insulin-like growth factor-1 receptor in the epidermis of transgenic mice
    • Wilker E, Bol D, Kiguchi K, Rupp T, Beltran L, DiGiovanni J. Enhancement of susceptibility to diverse skin tumor promoters by activation of the insulin-like growth factor-1 receptor in the epidermis of transgenic mice. Mol Carcinog 1999;25:122-31.
    • (1999) Mol Carcinog , vol.25 , pp. 122-131
    • Wilker, E.1    Bol, D.2    Kiguchi, K.3    Rupp, T.4    Beltran, L.5    DiGiovanni, J.6
  • 7
    • 0032079677 scopus 로고    scopus 로고
    • Metastasizing mammary carcinomas in H19 enhancers-Igf2 transgenic mice
    • Pravtcheva DD, Wise TL. Metastasizing mammary carcinomas in H19 enhancers-Igf2 transgenic mice. J Exp Zool 1998;281:43-57.
    • (1998) J Exp Zool , vol.281 , pp. 43-57
    • Pravtcheva, D.D.1    Wise, T.L.2
  • 8
    • 0028890744 scopus 로고
    • The insulin-like growth factor I receptor: A key to tumor growth?
    • Baserga R. The insulin-like growth factor I receptor: a key to tumor growth? Cancer Res 1995;55:249-52.
    • (1995) Cancer Res , vol.55 , pp. 249-252
    • Baserga, R.1
  • 9
    • 0028362024 scopus 로고
    • A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor
    • Coppola D, Ferber A, Miura M, et al. A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor. Mol Cell Biol 1994;14:4588-95.
    • (1994) Mol Cell Biol , vol.14 , pp. 4588-4595
    • Coppola, D.1    Ferber, A.2    Miura, M.3
  • 10
    • 0027366338 scopus 로고
    • Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor
    • Sell C, Rubini M, Rubin R, Liu JP, Efstratiadis A, Baserga R. Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor. Proc Natl Acad Sci U S A 1993;90:11217-21.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 11217-11221
    • Sell, C.1    Rubini, M.2    Rubin, R.3    Liu, J.P.4    Efstratiadis, A.5    Baserga, R.6
  • 11
    • 54049108939 scopus 로고    scopus 로고
    • Early drug development of inhibitors of the insulin-like growth factor-I receptor pathway: Lessons from the first clinical trials
    • Rodon J, DeSantos V, Ferry RJ, Jr., Kurzrock R. Early drug development of inhibitors of the insulin-like growth factor-I receptor pathway: lessons from the first clinical trials. Mol Cancer Ther 2008;7:2575-88.
    • (2008) Mol Cancer Ther , vol.7 , pp. 2575-2588
    • Rodon, J.1    DeSantos, V.2    Ferry Jr., R.J.3    Kurzrock, R.4
  • 12
    • 54049118086 scopus 로고    scopus 로고
    • Antixenograft tumor activity of a humanized anti-insulin-like growth factor-I receptor monoclonal antibody is associated with decreased AKT activation and glucose uptake
    • Shang Y, Mao Y, Batson J, et al. Antixenograft tumor activity of a humanized anti-insulin-like growth factor-I receptor monoclonal antibody is associated with decreased AKT activation and glucose uptake. Mol Cancer Ther 2008;7:2599-608.
    • (2008) Mol Cancer Ther , vol.7 , pp. 2599-2608
    • Shang, Y.1    Mao, Y.2    Batson, J.3
  • 13
    • 54249157471 scopus 로고    scopus 로고
    • Addiction to elevated insulin-like growth factor I receptor and initial modulation of the AKT pathway define the responsiveness of rhabdomyosarcoma to the targeting antibody
    • Cao L, Yu Y, Darko I, et al. Addiction to elevated insulin-like growth factor I receptor and initial modulation of the AKT pathway define the responsiveness of rhabdomyosarcoma to the targeting antibody. Cancer Res 2008;68:8039-48.
    • (2008) Cancer Res , vol.68 , pp. 8039-8048
    • Cao, L.1    Yu, Y.2    Darko, I.3
  • 14
    • 48549095270 scopus 로고    scopus 로고
    • Functional genomics identifies ABCC3 as a mediator of taxane resistance in HER2-amplified breast cancer
    • O'Brien C, Cavet G, Pandita A, et al. Functional genomics identifies ABCC3 as a mediator of taxane resistance in HER2-amplified breast cancer. Cancer Res 2008;68:5380-9.
    • (2008) Cancer Res , vol.68 , pp. 5380-5389
    • O'Brien, C.1    Cavet, G.2    Pandita, A.3
  • 15
    • 34948894931 scopus 로고    scopus 로고
    • Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL
    • Wagner KW, Punnoose EA, Januario T, et al. Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL. Nat Med 2007;13:1070-7.
    • (2007) Nat Med , vol.13 , pp. 1070-1077
    • Wagner, K.W.1    Punnoose, E.A.2    Januario, T.3
  • 16
    • 56449129810 scopus 로고    scopus 로고
    • Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate
    • Lewis Phillips GD, Li G, Dugger DL, et al. Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate. Cancer Res 2008;68:9280-90.
    • (2008) Cancer Res , vol.68 , pp. 9280-9290
    • Lewis Phillips, G.D.1    Li, G.2    Dugger, D.L.3
  • 17
    • 0019061918 scopus 로고
    • Ligand: A versatile computerized approach for characterization of ligand-binding systems
    • Munson PJ, Rodbard D. Ligand: a versatile computerized approach for characterization of ligand-binding systems. Anal Biochem 1980;107:220-39.
    • (1980) Anal Biochem , vol.107 , pp. 220-239
    • Munson, P.J.1    Rodbard, D.2
  • 18
    • 0034948896 scopus 로고    scopus 로고
    • A Bayesian framework for the analysis of microarray expression data: Regularized t-test and statistical inferences of gene changes
    • Baldi P, Long AD. A Bayesian framework for the analysis of microarray expression data: regularized t-test and statistical inferences of gene changes. Bioinformatics 2001;17:509-19.
    • (2001) Bioinformatics , vol.17 , pp. 509-519
    • Baldi, P.1    Long, A.D.2
  • 19
    • 0042424602 scopus 로고    scopus 로고
    • Statistical significance for genomewide studies
    • Storey JD, Tibshirani R. Statistical significance for genomewide studies. Proc Natl Acad Sci U S A 2003;100:9440-5.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 9440-9445
    • Storey, J.D.1    Tibshirani, R.2
  • 20
    • 33847246805 scopus 로고    scopus 로고
    • Oncomine 3.0: Genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles
    • Rhodes DR, Kalyana-Sundaram S, Mahavisno V, et al. Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles. Neoplasia 2007;9:166-80.
    • (2007) Neoplasia , vol.9 , pp. 166-180
    • Rhodes, D.R.1    Kalyana-Sundaram, S.2    Mahavisno, V.3
  • 21
    • 33750453743 scopus 로고    scopus 로고
    • Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells
    • Byron SA, Horwitz KB, Richer JK, Lange CA, Zhang X, Yee D. Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells. Br J Cancer 2006;95:1220-8.
    • (2006) Br J Cancer , vol.95 , pp. 1220-1228
    • Byron, S.A.1    Horwitz, K.B.2    Richer, J.K.3    Lange, C.A.4    Zhang, X.5    Yee, D.6
  • 22
    • 65349165810 scopus 로고    scopus 로고
    • Customizing the targeting of IGF-1 receptor
    • London, England
    • Baserga R. Customizing the targeting of IGF-1 receptor. Future Oncol (London, England) 2009;5:43-50.
    • (2009) Future Oncol , vol.5 , pp. 43-50
    • Baserga, R.1
  • 23
    • 0031079684 scopus 로고    scopus 로고
    • The IGF-I receptor in mitogenesis and transformation of mouse embryo cells: Role of receptor number
    • Rubini M, Hongo A, D'Ambrosio C, Baserga R. The IGF-I receptor in mitogenesis and transformation of mouse embryo cells: role of receptor number. Exp Cell Res 1997;230:284-92.
    • (1997) Exp Cell Res , vol.230 , pp. 284-292
    • Rubini, M.1    Hongo, A.2    D'Ambrosio, C.3    Baserga, R.4
  • 24
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • Sorlie T, Perou CM, Tibshirani R, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A 2001;98:10869-74.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 10869-10874
    • Sorlie, T.1    Perou, C.M.2    Tibshirani, R.3
  • 25
    • 8544284095 scopus 로고    scopus 로고
    • Role of estrogen receptor α in modulating IGF-I receptor signaling and function in breast cancer
    • Surmacz E, Bartucci M. Role of estrogen receptor α in modulating IGF-I receptor signaling and function in breast cancer. J Exp Clin Cancer Res 2004;23:385-94.
    • (2004) J Exp Clin Cancer Res , vol.23 , pp. 385-394
    • Surmacz, E.1    Bartucci, M.2
  • 26
    • 0033842834 scopus 로고    scopus 로고
    • Crosstalk between the insulin-like growth factors and estrogens in breast cancer
    • Yee D, Lee AV. Crosstalk between the insulin-like growth factors and estrogens in breast cancer. J Mammary Gland Biol Neoplasia 2000;5:107-15.
    • (2000) J Mammary Gland Biol Neoplasia , vol.5 , pp. 107-115
    • Yee, D.1    Lee, A.V.2
  • 27
    • 0036206491 scopus 로고    scopus 로고
    • Existing and emerging endocrine therapies for breast cancer
    • Dow KH. Existing and emerging endocrine therapies for breast cancer. Cancer Nurs 2002;25 Suppl 2:6-11S.
    • (2002) Cancer Nurs , vol.25 , Issue.SUPPL. 2
    • Dow, K.H.1
  • 28
    • 0024850428 scopus 로고
    • Short- and long-term estrogen deprivation of T47D human breast cancer cells in culture
    • Murphy CS, Meisner LF, Wu SQ, Jordan VC. Short- and long-term estrogen deprivation of T47D human breast cancer cells in culture. Eur J Cancer Clin Oncol 1989;25:1777-88.
    • (1989) Eur J Cancer Clin Oncol , vol.25 , pp. 1777-1788
    • Murphy, C.S.1    Meisner, L.F.2    Wu, S.Q.3    Jordan, V.C.4
  • 29
    • 0031585866 scopus 로고    scopus 로고
    • Overexpressed IGF-I receptors reduce estrogen growth requirements, enhance survival, and promote E-cadherin-mediated cell-cell adhesion in human breast cancer cells
    • Guvakova MA, Surmacz E. Overexpressed IGF-I receptors reduce estrogen growth requirements, enhance survival, and promote E-cadherin-mediated cell-cell adhesion in human breast cancer cells. Exp Cell Res 1997;231:149-62.
    • (1997) Exp Cell Res , vol.231 , pp. 149-162
    • Guvakova, M.A.1    Surmacz, E.2
  • 30
    • 25144503826 scopus 로고    scopus 로고
    • Cytoplasmic CD24 expression in colorectal cancer independently correlates with shortened patient survival
    • Weichert W, Denkert C, Burkhardt M, et al. Cytoplasmic CD24 expression in colorectal cancer independently correlates with shortened patient survival. Clin Cancer Res 2005;11:6574-81.
    • (2005) Clin Cancer Res , vol.11 , pp. 6574-6581
    • Weichert, W.1    Denkert, C.2    Burkhardt, M.3
  • 31
    • 51649111430 scopus 로고    scopus 로고
    • Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity
    • Vermeulen L, Todaro M, de Sousa Mello F, et al. Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity. Proc Natl Acad Sci U S A 2008;105:13427-32.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 13427-13432
    • Vermeulen, L.1    Todaro, M.2    de Sousa Mello, F.3
  • 32
    • 62449205665 scopus 로고    scopus 로고
    • Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition
    • Dallas NA, Xia L, Fan F, et al. Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition. Cancer Res 2009;69:1951-7.
    • (2009) Cancer Res , vol.69 , pp. 1951-1957
    • Dallas, N.A.1    Xia, L.2    Fan, F.3
  • 33
    • 34249072202 scopus 로고    scopus 로고
    • Molecular concepts analysis links tumors, pathways, mechanisms, and drugs
    • Rhodes DR, Kalyana-Sundaram S, Tomlins SA, et al. Molecular concepts analysis links tumors, pathways, mechanisms, and drugs. Neoplasia 2007;9:443-54.
    • (2007) Neoplasia , vol.9 , pp. 443-454
    • Rhodes, D.R.1    Kalyana-Sundaram, S.2    Tomlins, S.A.3
  • 34
    • 51649091930 scopus 로고    scopus 로고
    • Insulin-like growth factor-I activates gene transcription programs strongly associated with poor breast cancer prognosis
    • Creighton CJ, Casa A, Lazard Z, et al. Insulin-like growth factor-I activates gene transcription programs strongly associated with poor breast cancer prognosis. J Clin Oncol 2008;26:4078-85.
    • (2008) J Clin Oncol , vol.26 , pp. 4078-4085
    • Creighton, C.J.1    Casa, A.2    Lazard, Z.3
  • 35
    • 34249303463 scopus 로고    scopus 로고
    • Fiebig HH, Schuler J, Bausch N, Hofmann M, Metz T, Korrat A. Gene signatures developed from patient tumor explants grown in nude mice to predict tumor response to 11 cytotoxic drugs. Cancer Genomics Proteomics 2007;4:197-209.
    • Fiebig HH, Schuler J, Bausch N, Hofmann M, Metz T, Korrat A. Gene signatures developed from patient tumor explants grown in nude mice to predict tumor response to 11 cytotoxic drugs. Cancer Genomics Proteomics 2007;4:197-209.
  • 36
    • 0034760143 scopus 로고    scopus 로고
    • Herceptin alone or in combination with chemotherapy in the treatment of HER2-positive metastatic breast cancer: Pivotal trials
    • Baselga J. Herceptin alone or in combination with chemotherapy in the treatment of HER2-positive metastatic breast cancer: pivotal trials. Oncology 2001;61 Suppl 2:14-21.
    • (2001) Oncology , vol.61 , Issue.SUPPL. 2 , pp. 14-21
    • Baselga, J.1
  • 37
    • 0035712665 scopus 로고    scopus 로고
    • Leyland-Jones B. Maximizing the response to Herceptin therapy through optimal use and patient selection. Anticancer Drugs 2001;12Suppl 4:S11-7.
    • Leyland-Jones B. Maximizing the response to Herceptin therapy through optimal use and patient selection. Anticancer Drugs 2001;12Suppl 4:S11-7.
  • 38
    • 33846568336 scopus 로고    scopus 로고
    • American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer
    • Wolff AC, Hammond ME, Schwartz JN, et al. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. Arch Pathol Lab Med 2007;131:18.
    • (2007) Arch Pathol Lab Med , vol.131 , pp. 18
    • Wolff, A.C.1    Hammond, M.E.2    Schwartz, J.N.3
  • 39
    • 41849120821 scopus 로고    scopus 로고
    • EGFR-targeted therapy in colorectal cancer: Does immunohistochemistry deserve a role in predicting the response to cetuximab?
    • Valentini AM, Pirrelli M, Caruso ML. EGFR-targeted therapy in colorectal cancer: does immunohistochemistry deserve a role in predicting the response to cetuximab? Curr Opin Mol Ther 2008;10:124-31.
    • (2008) Curr Opin Mol Ther , vol.10 , pp. 124-131
    • Valentini, A.M.1    Pirrelli, M.2    Caruso, M.L.3
  • 40
    • 33947262154 scopus 로고    scopus 로고
    • Preclinical in vivo study of new insulin-like growth factor-I receptor-specific inhibitor in Ewing's sarcoma
    • Manara MC, Landuzzi L, Nanni P, et al. Preclinical in vivo study of new insulin-like growth factor-I receptor-specific inhibitor in Ewing's sarcoma. Clin Cancer Res 2007;13:1322-30.
    • (2007) Clin Cancer Res , vol.13 , pp. 1322-1330
    • Manara, M.C.1    Landuzzi, L.2    Nanni, P.3
  • 41
    • 0029838475 scopus 로고    scopus 로고
    • Insulin-like growth factor I receptor-mediated circuit in Ewing's sarcoma/peripheral neuroectodermal tumor: A possible therapeutic target
    • Scotlandi K, Benini S, Sarti M, et al. Insulin-like growth factor I receptor-mediated circuit in Ewing's sarcoma/peripheral neuroectodermal tumor: a possible therapeutic target. Cancer Res 1996;56:4570-4.
    • (1996) Cancer Res , vol.56 , pp. 4570-4574
    • Scotlandi, K.1    Benini, S.2    Sarti, M.3
  • 42
    • 47249106539 scopus 로고    scopus 로고
    • Targeting insulin-like growth factor 1 receptor in sarcomas
    • Scotlandi K, Picci P. Targeting insulin-like growth factor 1 receptor in sarcomas. Curr Opin Oncol 2008;20:419-27.
    • (2008) Curr Opin Oncol , vol.20 , pp. 419-427
    • Scotlandi, K.1    Picci, P.2
  • 43
    • 57149093206 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 receptor acts as a growth regulator in synovial sarcoma
    • Friedrichs N, Kuchler J, Endl E, et al. Insulin-like growth factor-1 receptor acts as a growth regulator in synovial sarcoma. J Pathol 2008;216:428-39.
    • (2008) J Pathol , vol.216 , pp. 428-439
    • Friedrichs, N.1    Kuchler, J.2    Endl, E.3
  • 44
    • 0033617446 scopus 로고    scopus 로고
    • Growth and differentiation signals by the insulin-like growth factor 1 receptor in hemopoietic cells are mediated through different pathways
    • Valentinis B, Romano G, Peruzzi F, et al. Growth and differentiation signals by the insulin-like growth factor 1 receptor in hemopoietic cells are mediated through different pathways. J Biol Chem 1999;274:12423-30.
    • (1999) J Biol Chem , vol.274 , pp. 12423-12430
    • Valentinis, B.1    Romano, G.2    Peruzzi, F.3
  • 45
    • 0040973209 scopus 로고    scopus 로고
    • Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells
    • Bruning JC, Winnay J, Cheatham B, Kahn CR. Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells. Mol Cell Biol 1997;17:1513-21.
    • (1997) Mol Cell Biol , vol.17 , pp. 1513-1521
    • Bruning, J.C.1    Winnay, J.2    Cheatham, B.3    Kahn, C.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.