메뉴 건너뛰기




Volumn 12, Issue 7, 2013, Pages 1213-1222

IGF-1R targeting increases the antitumor effects of DNA-damaging agents in SCLC model: An opportunity to increase the efficacy of standard therapy

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; CISPLATIN; PROTEIN KINASE B; ROBATUMUMAB; SOMATOMEDIN C RECEPTOR;

EID: 84880056834     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-12-1067     Document Type: Article
Times cited : (41)

References (21)
  • 1
    • 33750603100 scopus 로고    scopus 로고
    • Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: Analysis of the surveillance, epidemiologic, and end results database
    • DOI 10.1200/JCO.2005.04.4859
    • Govindan R, Page N, Morgensztern D, Read W, Tierney R, Vlahiotis A, et al. Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: analysis of the surveillance, epidemiologic, and end results database. J Clin Oncol 2006;24:4539-44. (Pubitemid 46630948)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.28 , pp. 4539-4544
    • Govindan, R.1    Page, N.2    Morgensztern, D.3    Read, W.4    Tierney, R.5    Vlahiotis, A.6    Spitznagel, E.L.7    Piccirillo, J.8
  • 2
    • 84876978699 scopus 로고    scopus 로고
    • Treatment of patients with small-cell lung cancer: From meta-analyses to clinical practice
    • Rossi A, Martelli O, Di Maio M. Treatment of patients with small-cell lung cancer: from meta-analyses to clinical practice. Cancer Treat Rev 2013;39:498-506.
    • (2013) Cancer Treat Rev , vol.39 , pp. 498-506
    • Rossi, A.1    Martelli, O.2    Di Maio, M.3
  • 3
    • 0025211405 scopus 로고
    • Autocrine function for insulin-like growth factor I in human small cell lung cancer cell lines and fresh tumor cells
    • Macaulay VM, Everard MJ, Teale JD, Trott PA, Wyk JJ, Van Smith IE, et al. Autocrine function for insulin-like growth factor I in human small cell lung cancer cell lines and fresh tumor cells. Cancer Res 1990;50:2511-7. (Pubitemid 20134519)
    • (1990) Cancer Research , vol.50 , Issue.8 , pp. 2511-2517
    • Macaulay, V.M.1    Everard, M.J.2    Teale, J.D.3    Trott, P.A.4    Van Wyk, J.J.5    Smith, I.E.6    Millar, J.L.7
  • 4
    • 84857640868 scopus 로고    scopus 로고
    • The insulin and insulin-like growth factor receptor family in neoplasia: An update
    • Pollak M. The insulin and insulin-like growth factor receptor family in neoplasia: an update. Nat Rev Cancer 2012;12:159-69.
    • (2012) Nat Rev Cancer , vol.12 , pp. 159-169
    • Pollak, M.1
  • 5
    • 69449097339 scopus 로고    scopus 로고
    • Emerging role of insulin-like growth factor receptor inhibitors in oncology: Early clinical trial results and future directions
    • Gualberto A, Pollak M. Emerging role of insulin-like growth factor receptor inhibitors in oncology: early clinical trial results and future directions. Oncogene 2009;28:3009-21.
    • (2009) Oncogene , vol.28 , pp. 3009-3021
    • Gualberto, A.1    Pollak, M.2
  • 6
    • 66149092327 scopus 로고    scopus 로고
    • Hyperactivation of the insulin-like growth factor receptor I signaling pathway is an essential event for cisplatin resistance of ovarian cancer cells
    • Eckstein N, Servan K, Hildebrandt B, Pölitz A, Von Jonquières G, Wolf-Kümmeth S, et al. Hyperactivation of the insulin-like growth factor receptor I signaling pathway is an essential event for cisplatin resistance of ovarian cancer cells. Cancer Res 2009;69:2996-3003.
    • (2009) Cancer Res , vol.69 , pp. 2996-3003
    • Eckstein, N.1    Servan, K.2    Hildebrandt, B.3    Pölitz, A.4    Von Jonquières, G.5    Wolf-Kümmeth, S.6
  • 8
    • 0035811559 scopus 로고    scopus 로고
    • Downregulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase
    • DOI 10.1038/sj.onc.1204565
    • Macaulay VM, Salisbury AJ, Bohula EA, Playford MP, Smorodinsky NI, Shiloh Y. Downregulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase. Oncogene 2001;20:4029-40. (Pubitemid 32681608)
    • (2001) Oncogene , vol.20 , Issue.30 , pp. 4029-4040
    • Macaulay, V.M.1    Salisbury, A.J.2    Bohula, E.A.3    Playford, M.P.4    Smorodinsky, N.I.5    Shiloh, Y.6
  • 9
    • 42949098453 scopus 로고    scopus 로고
    • Selective inhibition of SCLC growth by the A12 anti-IGF-1R monoclonal antibody correlates with inhibition of Akt
    • DOI 10.1016/j.lungcan.2007.09.023, PII S0169500207005983
    • Yeh J, Litz J, Hauck P, Ludwig DL, Krystal GW. Selective inhibition of SCLC growth by the A12 anti-IGF-1R monoclonal antibody correlates with inhibition of Akt. Lung Cancer 2008;60:166-74. (Pubitemid 351609143)
    • (2008) Lung Cancer , vol.60 , Issue.2 , pp. 166-174
    • Yeh, J.1    Litz, J.2    Hauck, P.3    Ludwig, D.L.4    Krystal, G.W.5
  • 10
    • 14644433735 scopus 로고    scopus 로고
    • The insulin-like growth factor-I receptor kinase inhibitor, NVP-ADW742, sensitizes small cell lung cancer cell lines to the effects of chemotherapy
    • DOI 10.1158/1078-0432.CCR-04-1544
    • Warshamana-Greene GS, Litz J, Buchdunger E, García- Echeverría C, Hofmann F, Krystal GW. The insulin-like growth factor-I receptor kinase inhibitor, NVP-ADW742, sensitizes small cell lung cancer cell lines to the effects of chemotherapy. Clin Cancer Res 2005;11:1563-71. (Pubitemid 40315241)
    • (2005) Clinical Cancer Research , vol.11 , Issue.4 , pp. 1563-1571
    • Warshamana-Greene, G.S.1    Litz, J.2    Buchdunger, E.3    Garcia-Echeverria, C.4    Hofmann, F.5    Krystal, G.W.6
  • 11
    • 84865688929 scopus 로고    scopus 로고
    • Development of tetravalent IgG1 dual targeting IGF-1R-EGFR antibodies with potent tumor inhibition
    • Croasdale R, Wartha K, Schanzer JM, Kuenkele K-P, Ries C, Mayer K, et al. Development of tetravalent IgG1 dual targeting IGF-1R-EGFR antibodies with potent tumor inhibition. Arch Biochem Biophys 2012;526:206-18.
    • (2012) Arch Biochem Biophys , vol.526 , pp. 206-218
    • Croasdale, R.1    Wartha, K.2    Schanzer, J.M.3    Kuenkele, K.-P.4    Ries, C.5    Mayer, K.6
  • 12
    • 77950974697 scopus 로고    scopus 로고
    • A phase I study of weekly R1507, a human monoclonal antibody insulin-like growth factor-I receptor antagonist, in patients with advanced solid tumors
    • Kurzrock R, Patnaik A, Aisner J, Warren T, Leong S, Benjamin R, et al. A phase I study of weekly R1507, a human monoclonal antibody insulin-like growth factor-I receptor antagonist, in patients with advanced solid tumors. Clin Cancer Res 2010;16:2458-65.
    • (2010) Clin Cancer Res , vol.16 , pp. 2458-2465
    • Kurzrock, R.1    Patnaik, A.2    Aisner, J.3    Warren, T.4    Leong, S.5    Benjamin, R.6
  • 13
    • 78650244025 scopus 로고    scopus 로고
    • Inhibition of BCL-2 in small cell lung cancer cell lines with oblimersen, an antisense BCL-2 oligodeoxynucleotide (ODN): In vitro and in vivo enhancement of radiation response
    • Loriot Y, Mordant P, Brown BD, Bourhis J, Soria J-C, Deutsch E. Inhibition of BCL-2 in small cell lung cancer cell lines with oblimersen, an antisense BCL-2 oligodeoxynucleotide (ODN): in vitro and in vivo enhancement of radiation response. Anticancer Res 2010;30:3869-78.
    • (2010) Anticancer Res , vol.30 , pp. 3869-3878
    • Loriot, Y.1    Mordant, P.2    Brown, B.D.3    Bourhis, J.4    Soria, J.-C.5    Deutsch, E.6
  • 16
    • 70350218696 scopus 로고    scopus 로고
    • High expression levels of total IGF-1R and sensitivity of NSCLC cells in vitro to an anti-IGF-1R antibody (R1507)
    • Gong Y, Yao E, Shen R, Goel A, Arcila M, Teruya-Feldstein J, et al. High expression levels of total IGF-1R and sensitivity of NSCLC cells in vitro to an anti-IGF-1R antibody (R1507). PLoS One 2009;4:e7273.
    • (2009) PLoS One , vol.4
    • Gong, Y.1    Yao, E.2    Shen, R.3    Goel, A.4    Arcila, M.5    Teruya-Feldstein, J.6
  • 17
    • 83255163333 scopus 로고    scopus 로고
    • R1507, a monoclonal antibody to the insulin-like growth factor 1 receptor, in patients with recurrent or refractory Ewing sarcoma family of tumors: Results of a phase II Sarcoma Alliance for Research through Collaboration study
    • Pappo AS, Patel SR, Crowley J, Reinke DK, Kuenkele K-P, Chawla SP, et al. R1507, a monoclonal antibody to the insulin-like growth factor 1 receptor, in patients with recurrent or refractory Ewing sarcoma family of tumors: results of a phase II Sarcoma Alliance for Research through Collaboration study. J Clin Oncol 2011;29:4541-7.
    • (2011) J Clin Oncol , vol.29 , pp. 4541-4547
    • Pappo, A.S.1    Patel, S.R.2    Crowley, J.3    Reinke, D.K.4    Kuenkele, K.-P.5    Chawla, S.P.6
  • 18
    • 75749102231 scopus 로고    scopus 로고
    • Safety, tolerability, and pharmacokinetics of the anti-IGF-1R monoclonal antibody figitumumab in patients with refractory adrenocortical carcinoma
    • Haluska P, Worden F, Olmos D, Yin D, Schteingart D, Batzel GN, et al. Safety, tolerability, and pharmacokinetics of the anti-IGF-1R monoclonal antibody figitumumab in patients with refractory adrenocortical carcinoma. Cancer Chemother Pharmacol 2010;65:765-73.
    • (2010) Cancer Chemother Pharmacol , vol.65 , pp. 765-773
    • Haluska, P.1    Worden, F.2    Olmos, D.3    Yin, D.4    Schteingart, D.5    Batzel, G.N.6
  • 20
    • 80052868947 scopus 로고    scopus 로고
    • Dual kinase inhibition of EGFR and HER2 overcomes resistance to cetuximab in a novel in vivo model of acquired cetuximab resistance
    • Quesnelle KM, Grandis JR. Dual kinase inhibition of EGFR and HER2 overcomes resistance to cetuximab in a novel in vivo model of acquired cetuximab resistance. Clin Cancer Res 2011;17:5935-44.
    • (2011) Clin Cancer Res , vol.17 , pp. 5935-5944
    • Quesnelle, K.M.1    Grandis, J.R.2
  • 21
    • 77953973648 scopus 로고    scopus 로고
    • Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy
    • Ulanet DB, Ludwig DL, Kahn CR, Hanahan D. Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy. Proc Natl Acad Sci U S A 2010;107:10791-8. Program
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 10791-10798
    • Ulanet, D.B.1    Ludwig, D.L.2    Kahn, C.R.3    Hanahan, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.