-
1
-
-
33750603100
-
Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: Analysis of the surveillance, epidemiologic, and end results database
-
DOI 10.1200/JCO.2005.04.4859
-
Govindan R, Page N, Morgensztern D, Read W, Tierney R, Vlahiotis A, et al. Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: analysis of the surveillance, epidemiologic, and end results database. J Clin Oncol 2006;24:4539-44. (Pubitemid 46630948)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.28
, pp. 4539-4544
-
-
Govindan, R.1
Page, N.2
Morgensztern, D.3
Read, W.4
Tierney, R.5
Vlahiotis, A.6
Spitznagel, E.L.7
Piccirillo, J.8
-
2
-
-
84876978699
-
Treatment of patients with small-cell lung cancer: From meta-analyses to clinical practice
-
Rossi A, Martelli O, Di Maio M. Treatment of patients with small-cell lung cancer: from meta-analyses to clinical practice. Cancer Treat Rev 2013;39:498-506.
-
(2013)
Cancer Treat Rev
, vol.39
, pp. 498-506
-
-
Rossi, A.1
Martelli, O.2
Di Maio, M.3
-
3
-
-
0025211405
-
Autocrine function for insulin-like growth factor I in human small cell lung cancer cell lines and fresh tumor cells
-
Macaulay VM, Everard MJ, Teale JD, Trott PA, Wyk JJ, Van Smith IE, et al. Autocrine function for insulin-like growth factor I in human small cell lung cancer cell lines and fresh tumor cells. Cancer Res 1990;50:2511-7. (Pubitemid 20134519)
-
(1990)
Cancer Research
, vol.50
, Issue.8
, pp. 2511-2517
-
-
Macaulay, V.M.1
Everard, M.J.2
Teale, J.D.3
Trott, P.A.4
Van Wyk, J.J.5
Smith, I.E.6
Millar, J.L.7
-
4
-
-
84857640868
-
The insulin and insulin-like growth factor receptor family in neoplasia: An update
-
Pollak M. The insulin and insulin-like growth factor receptor family in neoplasia: an update. Nat Rev Cancer 2012;12:159-69.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 159-169
-
-
Pollak, M.1
-
5
-
-
69449097339
-
Emerging role of insulin-like growth factor receptor inhibitors in oncology: Early clinical trial results and future directions
-
Gualberto A, Pollak M. Emerging role of insulin-like growth factor receptor inhibitors in oncology: early clinical trial results and future directions. Oncogene 2009;28:3009-21.
-
(2009)
Oncogene
, vol.28
, pp. 3009-3021
-
-
Gualberto, A.1
Pollak, M.2
-
6
-
-
66149092327
-
Hyperactivation of the insulin-like growth factor receptor I signaling pathway is an essential event for cisplatin resistance of ovarian cancer cells
-
Eckstein N, Servan K, Hildebrandt B, Pölitz A, Von Jonquières G, Wolf-Kümmeth S, et al. Hyperactivation of the insulin-like growth factor receptor I signaling pathway is an essential event for cisplatin resistance of ovarian cancer cells. Cancer Res 2009;69:2996-3003.
-
(2009)
Cancer Res
, vol.69
, pp. 2996-3003
-
-
Eckstein, N.1
Servan, K.2
Hildebrandt, B.3
Pölitz, A.4
Von Jonquières, G.5
Wolf-Kümmeth, S.6
-
7
-
-
0035852706
-
ATM-dependent expression of the insulin-like growth factor-I receptor in a pathway regulating radiation response
-
DOI 10.1073/pnas.041416598
-
Peretz S, Jensen R, Baserga R, Glazer PM. ATM-dependent expression of the insulin-like growth factor-I receptor in a pathway regulating radiation response. Proc Natl Acad Sci U S A 2001;98:1676-81. (Pubitemid 32165557)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.4
, pp. 1676-1681
-
-
Peretz, S.1
Jensen, R.2
Baserga, R.3
Glazer, P.M.4
-
8
-
-
0035811559
-
Downregulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase
-
DOI 10.1038/sj.onc.1204565
-
Macaulay VM, Salisbury AJ, Bohula EA, Playford MP, Smorodinsky NI, Shiloh Y. Downregulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase. Oncogene 2001;20:4029-40. (Pubitemid 32681608)
-
(2001)
Oncogene
, vol.20
, Issue.30
, pp. 4029-4040
-
-
Macaulay, V.M.1
Salisbury, A.J.2
Bohula, E.A.3
Playford, M.P.4
Smorodinsky, N.I.5
Shiloh, Y.6
-
9
-
-
42949098453
-
Selective inhibition of SCLC growth by the A12 anti-IGF-1R monoclonal antibody correlates with inhibition of Akt
-
DOI 10.1016/j.lungcan.2007.09.023, PII S0169500207005983
-
Yeh J, Litz J, Hauck P, Ludwig DL, Krystal GW. Selective inhibition of SCLC growth by the A12 anti-IGF-1R monoclonal antibody correlates with inhibition of Akt. Lung Cancer 2008;60:166-74. (Pubitemid 351609143)
-
(2008)
Lung Cancer
, vol.60
, Issue.2
, pp. 166-174
-
-
Yeh, J.1
Litz, J.2
Hauck, P.3
Ludwig, D.L.4
Krystal, G.W.5
-
10
-
-
14644433735
-
The insulin-like growth factor-I receptor kinase inhibitor, NVP-ADW742, sensitizes small cell lung cancer cell lines to the effects of chemotherapy
-
DOI 10.1158/1078-0432.CCR-04-1544
-
Warshamana-Greene GS, Litz J, Buchdunger E, García- Echeverría C, Hofmann F, Krystal GW. The insulin-like growth factor-I receptor kinase inhibitor, NVP-ADW742, sensitizes small cell lung cancer cell lines to the effects of chemotherapy. Clin Cancer Res 2005;11:1563-71. (Pubitemid 40315241)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.4
, pp. 1563-1571
-
-
Warshamana-Greene, G.S.1
Litz, J.2
Buchdunger, E.3
Garcia-Echeverria, C.4
Hofmann, F.5
Krystal, G.W.6
-
11
-
-
84865688929
-
Development of tetravalent IgG1 dual targeting IGF-1R-EGFR antibodies with potent tumor inhibition
-
Croasdale R, Wartha K, Schanzer JM, Kuenkele K-P, Ries C, Mayer K, et al. Development of tetravalent IgG1 dual targeting IGF-1R-EGFR antibodies with potent tumor inhibition. Arch Biochem Biophys 2012;526:206-18.
-
(2012)
Arch Biochem Biophys
, vol.526
, pp. 206-218
-
-
Croasdale, R.1
Wartha, K.2
Schanzer, J.M.3
Kuenkele, K.-P.4
Ries, C.5
Mayer, K.6
-
12
-
-
77950974697
-
A phase I study of weekly R1507, a human monoclonal antibody insulin-like growth factor-I receptor antagonist, in patients with advanced solid tumors
-
Kurzrock R, Patnaik A, Aisner J, Warren T, Leong S, Benjamin R, et al. A phase I study of weekly R1507, a human monoclonal antibody insulin-like growth factor-I receptor antagonist, in patients with advanced solid tumors. Clin Cancer Res 2010;16:2458-65.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 2458-2465
-
-
Kurzrock, R.1
Patnaik, A.2
Aisner, J.3
Warren, T.4
Leong, S.5
Benjamin, R.6
-
13
-
-
78650244025
-
Inhibition of BCL-2 in small cell lung cancer cell lines with oblimersen, an antisense BCL-2 oligodeoxynucleotide (ODN): In vitro and in vivo enhancement of radiation response
-
Loriot Y, Mordant P, Brown BD, Bourhis J, Soria J-C, Deutsch E. Inhibition of BCL-2 in small cell lung cancer cell lines with oblimersen, an antisense BCL-2 oligodeoxynucleotide (ODN): in vitro and in vivo enhancement of radiation response. Anticancer Res 2010;30:3869-78.
-
(2010)
Anticancer Res
, vol.30
, pp. 3869-3878
-
-
Loriot, Y.1
Mordant, P.2
Brown, B.D.3
Bourhis, J.4
Soria, J.-C.5
Deutsch, E.6
-
14
-
-
46149104384
-
Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumors
-
DOI 10.1073/pnas.0803383105
-
Tarn C, Rink L, Merkel E, Flieder D, Pathak H, Koumbi D, et al. Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumors. Proc Natl Acad Sci U S A 2008;105:8387-92. (Pubitemid 351904765)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.24
, pp. 8387-8392
-
-
Tarn, C.1
Rink, L.2
Merkel, E.3
Flieder, D.4
Pathak, H.5
Koumbi, D.6
Testa, J.R.7
Eisenberg, B.8
Von Mehren, M.9
Godwin, A.K.10
-
15
-
-
80052023514
-
Guidelines for preclinical and early phase clinical assessment of novel radiosensitisers
-
Harrington KJ, Billingham LJ, Brunner TB, Burnet NG, Chan CS, Hoskin P, et al. Guidelines for preclinical and early phase clinical assessment of novel radiosensitisers. Br J Cancer 2011;105:628-39.
-
(2011)
Br J Cancer
, vol.105
, pp. 628-639
-
-
Harrington, K.J.1
Billingham, L.J.2
Brunner, T.B.3
Burnet, N.G.4
Chan, C.S.5
Hoskin, P.6
-
16
-
-
70350218696
-
High expression levels of total IGF-1R and sensitivity of NSCLC cells in vitro to an anti-IGF-1R antibody (R1507)
-
Gong Y, Yao E, Shen R, Goel A, Arcila M, Teruya-Feldstein J, et al. High expression levels of total IGF-1R and sensitivity of NSCLC cells in vitro to an anti-IGF-1R antibody (R1507). PLoS One 2009;4:e7273.
-
(2009)
PLoS One
, vol.4
-
-
Gong, Y.1
Yao, E.2
Shen, R.3
Goel, A.4
Arcila, M.5
Teruya-Feldstein, J.6
-
17
-
-
83255163333
-
R1507, a monoclonal antibody to the insulin-like growth factor 1 receptor, in patients with recurrent or refractory Ewing sarcoma family of tumors: Results of a phase II Sarcoma Alliance for Research through Collaboration study
-
Pappo AS, Patel SR, Crowley J, Reinke DK, Kuenkele K-P, Chawla SP, et al. R1507, a monoclonal antibody to the insulin-like growth factor 1 receptor, in patients with recurrent or refractory Ewing sarcoma family of tumors: results of a phase II Sarcoma Alliance for Research through Collaboration study. J Clin Oncol 2011;29:4541-7.
-
(2011)
J Clin Oncol
, vol.29
, pp. 4541-4547
-
-
Pappo, A.S.1
Patel, S.R.2
Crowley, J.3
Reinke, D.K.4
Kuenkele, K.-P.5
Chawla, S.P.6
-
18
-
-
75749102231
-
Safety, tolerability, and pharmacokinetics of the anti-IGF-1R monoclonal antibody figitumumab in patients with refractory adrenocortical carcinoma
-
Haluska P, Worden F, Olmos D, Yin D, Schteingart D, Batzel GN, et al. Safety, tolerability, and pharmacokinetics of the anti-IGF-1R monoclonal antibody figitumumab in patients with refractory adrenocortical carcinoma. Cancer Chemother Pharmacol 2010;65:765-73.
-
(2010)
Cancer Chemother Pharmacol
, vol.65
, pp. 765-773
-
-
Haluska, P.1
Worden, F.2
Olmos, D.3
Yin, D.4
Schteingart, D.5
Batzel, G.N.6
-
19
-
-
65549090180
-
Trastuzumab-induced HER reprogramming in "resistant" breast carcinoma cells
-
Narayan M, Wilken JA, Harris LN, Baron AT, Kimbler KD, Maihle NJ. Trastuzumab-induced HER reprogramming in "resistant" breast carcinoma cells. Cancer Res 2009;69:2191-4.
-
(2009)
Cancer Res
, vol.69
, pp. 2191-2194
-
-
Narayan, M.1
Wilken, J.A.2
Harris, L.N.3
Baron, A.T.4
Kimbler, K.D.5
Maihle, N.J.6
-
20
-
-
80052868947
-
Dual kinase inhibition of EGFR and HER2 overcomes resistance to cetuximab in a novel in vivo model of acquired cetuximab resistance
-
Quesnelle KM, Grandis JR. Dual kinase inhibition of EGFR and HER2 overcomes resistance to cetuximab in a novel in vivo model of acquired cetuximab resistance. Clin Cancer Res 2011;17:5935-44.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 5935-5944
-
-
Quesnelle, K.M.1
Grandis, J.R.2
-
21
-
-
77953973648
-
Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy
-
Ulanet DB, Ludwig DL, Kahn CR, Hanahan D. Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy. Proc Natl Acad Sci U S A 2010;107:10791-8. Program
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 10791-10798
-
-
Ulanet, D.B.1
Ludwig, D.L.2
Kahn, C.R.3
Hanahan, D.4
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