Immune dysregulation and cognitive vulnerability in the aging brain: Interactions of microglia, IL-1β, BDNF and synaptic plasticity

Neuropharmacology

Volumn 96, Issue PA, 2015, Pages 11-18

  Patterson, Susan L ^a  

^a TEMPLE UNIVERSITY   (United States)

Author keywords

Aging; BDNF; Cognitive vulnerability; IL 1 ; Infection; Inflammation; Memory; Microglia; Synaptic plasticity

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; INTERLEUKIN 1BETA; NEUROTROPIN; AUTACOID;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COGNITION; ENCEPHALITIS; HIPPOCAMPUS; IMMUNE DYSREGULATION; IMMUNE SYSTEM; IMMUNOCOMPETENT CELL; INFLAMMATION; MEMORY; MEMORY DISORDER; MICROGLIA; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE; TH1 CELL; ANIMAL; BRAIN; COGNITION DISORDERS; HUMAN; IMMUNOLOGY; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; PSYCHOLOGY;

AGING; ANIMALS; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; COGNITION DISORDERS; HIPPOCAMPUS; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; MICROGLIA; NEURONAL PLASTICITY;

EID: 84930929500     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2014.12.020     Document Type: Review

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