메뉴 건너뛰기




Volumn 65, Issue 4, 2009, Pages 304-312

Systemic Inflammation Induces Acute Behavioral and Cognitive Changes and Accelerates Neurodegenerative Disease

Author keywords

Alzheimer's disease; cytokines; delirium; inflammation; microglial priming; neurodegeneration; systemic

Indexed keywords

BETA INTERFERON; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

EID: 58349119112     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2008.07.024     Document Type: Article
Times cited : (459)

References (52)
  • 2
    • 0038375640 scopus 로고    scopus 로고
    • Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease: Systematic review and meta-analysis of observational studies
    • Etminan M., Gill S., and Samii A. Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease: Systematic review and meta-analysis of observational studies. BMJ 327 (2003) 128
    • (2003) BMJ , vol.327 , pp. 128
    • Etminan, M.1    Gill, S.2    Samii, A.3
  • 3
    • 0141453824 scopus 로고    scopus 로고
    • The potential of anti-inflammatory drugs for the treatment of Alzheimer's disease
    • Aisen P.S. The potential of anti-inflammatory drugs for the treatment of Alzheimer's disease. Lancet Neurol 1 (2002) 279-284
    • (2002) Lancet Neurol , vol.1 , pp. 279-284
    • Aisen, P.S.1
  • 4
    • 32044463387 scopus 로고    scopus 로고
    • Coxibs and Alzheimer's disease: Should they stay or should they go?
    • Firuzi O., and Pratico D. Coxibs and Alzheimer's disease: Should they stay or should they go?. Ann Neurol 59 (2006) 219-228
    • (2006) Ann Neurol , vol.59 , pp. 219-228
    • Firuzi, O.1    Pratico, D.2
  • 5
    • 33847339301 scopus 로고    scopus 로고
    • NSAIDs and Alzheimer disease: Epidemiological, animal model and clinical studies
    • McGeer P.L., and McGeer E.G. NSAIDs and Alzheimer disease: Epidemiological, animal model and clinical studies. Neurobiol Aging 28 (2007) 639-647
    • (2007) Neurobiol Aging , vol.28 , pp. 639-647
    • McGeer, P.L.1    McGeer, E.G.2
  • 7
    • 0031283123 scopus 로고    scopus 로고
    • Causes and prognosis of delirium in elderly patients admitted to a district general hospital
    • George J., Bleasdale S., and Singleton S.J. Causes and prognosis of delirium in elderly patients admitted to a district general hospital. Age Ageing 26 (1997) 423-427
    • (1997) Age Ageing , vol.26 , pp. 423-427
    • George, J.1    Bleasdale, S.2    Singleton, S.J.3
  • 8
    • 0034484584 scopus 로고    scopus 로고
    • Delirium in elderly people without severe predisposing disorders: Etiology and 1-year prognosis after discharge
    • Rahkonen T., Makela H., Paanila S., Halonen P., Sivenius J., and Sulkava R. Delirium in elderly people without severe predisposing disorders: Etiology and 1-year prognosis after discharge. Int Psychogeriatr 12 (2000) 473-481
    • (2000) Int Psychogeriatr , vol.12 , pp. 473-481
    • Rahkonen, T.1    Makela, H.2    Paanila, S.3    Halonen, P.4    Sivenius, J.5    Sulkava, R.6
  • 12
    • 4644233272 scopus 로고    scopus 로고
    • Cytokine-induced sickness behaviour: A neuroimmune response to activation of innate immunity
    • Dantzer R. Cytokine-induced sickness behaviour: A neuroimmune response to activation of innate immunity. Eur J Pharmacol 500 (2004) 399-411
    • (2004) Eur J Pharmacol , vol.500 , pp. 399-411
    • Dantzer, R.1
  • 13
    • 0037067048 scopus 로고    scopus 로고
    • Peripheral infection evokes exaggerated sickness behaviour in pre-clinical murine prion disease
    • Combrinck M.I., Perry V.H., and Cunningham C. Peripheral infection evokes exaggerated sickness behaviour in pre-clinical murine prion disease. Neuroscience 112 (2002) 7-11
    • (2002) Neuroscience , vol.112 , pp. 7-11
    • Combrinck, M.I.1    Perry, V.H.2    Cunningham, C.3
  • 14
    • 0029784248 scopus 로고    scopus 로고
    • Evidence for an early inflammatory response in the central nervous system of mice with scrapie
    • Betmouni S., Perry V.H., and Gordon J.L. Evidence for an early inflammatory response in the central nervous system of mice with scrapie. Neuroscience 74 (1996) 1-5
    • (1996) Neuroscience , vol.74 , pp. 1-5
    • Betmouni, S.1    Perry, V.H.2    Gordon, J.L.3
  • 15
    • 0036230262 scopus 로고    scopus 로고
    • Transforming growth factor beta1, the dominant cytokine in murine prion disease: Influence on inflammatory cytokine synthesis and alteration of vascular extracellular matrix
    • Cunningham C., Boche D., and Perry V.H. Transforming growth factor beta1, the dominant cytokine in murine prion disease: Influence on inflammatory cytokine synthesis and alteration of vascular extracellular matrix. Neuropathol Appl Neurobiol 28 (2002) 107-119
    • (2002) Neuropathol Appl Neurobiol , vol.28 , pp. 107-119
    • Cunningham, C.1    Boche, D.2    Perry, V.H.3
  • 16
    • 16244394033 scopus 로고    scopus 로고
    • Comparison of inflammatory and acute-phase responses in the brain and peripheral organs of the ME7 model of prion disease
    • Cunningham C., Wilcockson D.C., Boche D., and Perry V.H. Comparison of inflammatory and acute-phase responses in the brain and peripheral organs of the ME7 model of prion disease. J Virol 79 (2005) 5174-5184
    • (2005) J Virol , vol.79 , pp. 5174-5184
    • Cunningham, C.1    Wilcockson, D.C.2    Boche, D.3    Perry, V.H.4
  • 17
    • 0035111243 scopus 로고    scopus 로고
    • Absence of detectable IL-1beta production in murine prion disease: A model of chronic neurodegeneration
    • Walsh D.T., Betmouni S., and Perry V.H. Absence of detectable IL-1beta production in murine prion disease: A model of chronic neurodegeneration. J Neuropathol Exp Neurol 60 (2001) 173-182
    • (2001) J Neuropathol Exp Neurol , vol.60 , pp. 173-182
    • Walsh, D.T.1    Betmouni, S.2    Perry, V.H.3
  • 18
    • 27144470284 scopus 로고    scopus 로고
    • Central and systemic endotoxin challenges exacerbate the local inflammatory response and increase neuronal death during chronic neurodegeneration
    • Cunningham C., Wilcockson D.C., Campion S., Lunnon K., and Perry V.H. Central and systemic endotoxin challenges exacerbate the local inflammatory response and increase neuronal death during chronic neurodegeneration. J Neurosci 25 (2005) 9275-9284
    • (2005) J Neurosci , vol.25 , pp. 9275-9284
    • Cunningham, C.1    Wilcockson, D.C.2    Campion, S.3    Lunnon, K.4    Perry, V.H.5
  • 20
    • 33947692628 scopus 로고    scopus 로고
    • Burrowing in rodents: A sensitive method for detecting behavioral dysfunction
    • Deacon R.M. Burrowing in rodents: A sensitive method for detecting behavioral dysfunction. Nat Protoc 1 (2006) 118-121
    • (2006) Nat Protoc , vol.1 , pp. 118-121
    • Deacon, R.M.1
  • 21
    • 26944437441 scopus 로고    scopus 로고
    • MCP-1 and murine prion disease: Separation of early behavioural dysfunction from overt clinical disease
    • Felton L.M., Cunningham C., Rankine E.L., Waters S., Boche D., and Perry V.H. MCP-1 and murine prion disease: Separation of early behavioural dysfunction from overt clinical disease. Neurobiol Dis 20 (2005) 283-295
    • (2005) Neurobiol Dis , vol.20 , pp. 283-295
    • Felton, L.M.1    Cunningham, C.2    Rankine, E.L.3    Waters, S.4    Boche, D.5    Perry, V.H.6
  • 23
    • 0035999636 scopus 로고    scopus 로고
    • Learning impairments of hippocampal-lesioned mice in a paddling pool
    • Deacon R.M., and Rawlins J.N. Learning impairments of hippocampal-lesioned mice in a paddling pool. Behav Neurosci 116 (2002) 472-478
    • (2002) Behav Neurosci , vol.116 , pp. 472-478
    • Deacon, R.M.1    Rawlins, J.N.2
  • 25
    • 78651159795 scopus 로고
    • A new method for the measurement of muscle relaxation in white mice [in German]
    • Kondziela W. A new method for the measurement of muscle relaxation in white mice [in German]. Arch Int Pharmacodyn Ther 152 (1964) 277-284
    • (1964) Arch Int Pharmacodyn Ther , vol.152 , pp. 277-284
    • Kondziela, W.1
  • 26
    • 34047158785 scopus 로고    scopus 로고
    • The sickness behaviour and CNS inflammatory mediator profile induced by systemic challenge of mice with synthetic double-stranded RNA (poly I:C)
    • Cunningham C., Campion S., Teeling J., Felton L., and Perry V.H. The sickness behaviour and CNS inflammatory mediator profile induced by systemic challenge of mice with synthetic double-stranded RNA (poly I:C). Brain Behav Immun 21 (2007) 490-502
    • (2007) Brain Behav Immun , vol.21 , pp. 490-502
    • Cunningham, C.1    Campion, S.2    Teeling, J.3    Felton, L.4    Perry, V.H.5
  • 27
    • 0017843481 scopus 로고
    • Lipid A-induced tolerance and hyperreactivity to hypothermia in mice
    • Greer G.G., and Rietschel E.T. Lipid A-induced tolerance and hyperreactivity to hypothermia in mice. Infect Immun 19 (1978) 357-368
    • (1978) Infect Immun , vol.19 , pp. 357-368
    • Greer, G.G.1    Rietschel, E.T.2
  • 28
    • 0037315747 scopus 로고    scopus 로고
    • The impact of systemic infection on the progression of neurodegenerative disease
    • Perry V.H., Newman T.A., and Cunningham C. The impact of systemic infection on the progression of neurodegenerative disease. Nat Rev Neurosci 4 (2003) 103-112
    • (2003) Nat Rev Neurosci , vol.4 , pp. 103-112
    • Perry, V.H.1    Newman, T.A.2    Cunningham, C.3
  • 30
    • 0027352040 scopus 로고
    • Altered antigen expression of microglia in the aged rodent CNS
    • Perry V.H., Matyszak M.K., and Fearn S. Altered antigen expression of microglia in the aged rodent CNS. Glia 7 (1993) 60-67
    • (1993) Glia , vol.7 , pp. 60-67
    • Perry, V.H.1    Matyszak, M.K.2    Fearn, S.3
  • 31
    • 0034883360 scopus 로고    scopus 로고
    • Early behavioural changes in scrapie-affected mice and the influence of dapsone
    • Guenther K., Deacon R.M., Perry V.H., and Rawlins J.N. Early behavioural changes in scrapie-affected mice and the influence of dapsone. Eur J Neurosci 14 (2001) 401-409
    • (2001) Eur J Neurosci , vol.14 , pp. 401-409
    • Guenther, K.1    Deacon, R.M.2    Perry, V.H.3    Rawlins, J.N.4
  • 32
    • 0038809966 scopus 로고    scopus 로고
    • Synaptic changes characterize early behavioural signs in the ME7 model of murine prion disease
    • Cunningham C., Deacon R., Wells H., Boche D., Waters S., Diniz C.P., et al. Synaptic changes characterize early behavioural signs in the ME7 model of murine prion disease. Eur J Neurosci 17 (2003) 2147-2155
    • (2003) Eur J Neurosci , vol.17 , pp. 2147-2155
    • Cunningham, C.1    Deacon, R.2    Wells, H.3    Boche, D.4    Waters, S.5    Diniz, C.P.6
  • 34
    • 20544463202 scopus 로고    scopus 로고
    • Peripheral lipopolysaccharide administration impairs two-way active avoidance conditioning in C57BL/6J mice
    • Sparkman N.L., Kohman R.A., Garcia A.K., and Boehm G.W. Peripheral lipopolysaccharide administration impairs two-way active avoidance conditioning in C57BL/6J mice. Physiol Behav 85 (2005) 278-288
    • (2005) Physiol Behav , vol.85 , pp. 278-288
    • Sparkman, N.L.1    Kohman, R.A.2    Garcia, A.K.3    Boehm, G.W.4
  • 35
    • 24944568523 scopus 로고    scopus 로고
    • Bacterial endotoxin-induced behavioral alterations in two variations of the Morris water maze
    • Sparkman N.L., Kohman R.A., Scott V.J., and Boehm G.W. Bacterial endotoxin-induced behavioral alterations in two variations of the Morris water maze. Physiol Behav 86 (2005) 244-251
    • (2005) Physiol Behav , vol.86 , pp. 244-251
    • Sparkman, N.L.1    Kohman, R.A.2    Scott, V.J.3    Boehm, G.W.4
  • 36
    • 15744382068 scopus 로고    scopus 로고
    • Effects of intraperitoneal lipopolysaccharide on Morris maze performance in year-old and 2-month-old female C57BL/6J mice
    • Sparkman N.L., Martin L.A., Calvert W.S., and Boehm G.W. Effects of intraperitoneal lipopolysaccharide on Morris maze performance in year-old and 2-month-old female C57BL/6J mice. Behav Brain Res 159 (2005) 145-151
    • (2005) Behav Brain Res , vol.159 , pp. 145-151
    • Sparkman, N.L.1    Martin, L.A.2    Calvert, W.S.3    Boehm, G.W.4
  • 37
    • 38449087454 scopus 로고    scopus 로고
    • Age increases vulnerability to bacterial endotoxin-induced behavioral decrements
    • Kohman R.A., Tarr A.J., Byler S.L., and Boehm G.W. Age increases vulnerability to bacterial endotoxin-induced behavioral decrements. Physiol Behav 91 (2007) 561-565
    • (2007) Physiol Behav , vol.91 , pp. 561-565
    • Kohman, R.A.1    Tarr, A.J.2    Byler, S.L.3    Boehm, G.W.4
  • 39
    • 38649119160 scopus 로고    scopus 로고
    • Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system
    • Chen J., Buchanan J.B., Sparkman N.L., Godbout J.P., Freund G.G., and Johnson R.W. Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system. Brain Behav Immun 22 (2008) 301-311
    • (2008) Brain Behav Immun , vol.22 , pp. 301-311
    • Chen, J.1    Buchanan, J.B.2    Sparkman, N.L.3    Godbout, J.P.4    Freund, G.G.5    Johnson, R.W.6
  • 40
    • 0037151889 scopus 로고    scopus 로고
    • Delirium
    • Brown T.M., and Boyle M.F. Delirium. BMJ 325 (2002) 644-647
    • (2002) BMJ , vol.325 , pp. 644-647
    • Brown, T.M.1    Boyle, M.F.2
  • 41
    • 0034680289 scopus 로고    scopus 로고
    • Prevalence and detection of delirium in elderly emergency department patients
    • Elie M., Rousseau F., Cole M., Primeau F., McCusker J., and Bellavance F. Prevalence and detection of delirium in elderly emergency department patients. CMAJ 163 (2000) 977-981
    • (2000) CMAJ , vol.163 , pp. 977-981
    • Elie, M.1    Rousseau, F.2    Cole, M.3    Primeau, F.4    McCusker, J.5    Bellavance, F.6
  • 42
    • 0036800422 scopus 로고    scopus 로고
    • Delirium superimposed on dementia: A systematic review
    • Fick D.M., Agostini J.V., and Inouye S.K. Delirium superimposed on dementia: A systematic review. J Am Geriatr Soc 50 (2002) 1723-1732
    • (2002) J Am Geriatr Soc , vol.50 , pp. 1723-1732
    • Fick, D.M.1    Agostini, J.V.2    Inouye, S.K.3
  • 43
    • 1242336763 scopus 로고    scopus 로고
    • Exacerbation of motor neuron disease by chronic stimulation of innate immunity in a mouse model of amyotrophic lateral sclerosis
    • Nguyen M.D., D'Aigle T., Gowing G., Julien J.P., and Rivest S. Exacerbation of motor neuron disease by chronic stimulation of innate immunity in a mouse model of amyotrophic lateral sclerosis. J Neurosci 24 (2004) 1340-1349
    • (2004) J Neurosci , vol.24 , pp. 1340-1349
    • Nguyen, M.D.1    D'Aigle, T.2    Gowing, G.3    Julien, J.P.4    Rivest, S.5
  • 44
    • 25644456097 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease
    • Kitazawa M., Oddo S., Yamasaki T.R., Green K.N., and LaFerla F.M. Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease. J Neurosci 25 (2005) 8843-8853
    • (2005) J Neurosci , vol.25 , pp. 8843-8853
    • Kitazawa, M.1    Oddo, S.2    Yamasaki, T.R.3    Green, K.N.4    LaFerla, F.M.5
  • 45
    • 0035704245 scopus 로고    scopus 로고
    • Endogenous brain cytokine mRNA and inflammatory responses to lipopolysaccharide are elevated in the Tg2576 transgenic mouse model of Alzheimer's disease
    • Sly L.M., Krzesicki R.F., Brashler J.R., Buhl A.E., McKinley D.D., Carter D.B., and Chin J.E. Endogenous brain cytokine mRNA and inflammatory responses to lipopolysaccharide are elevated in the Tg2576 transgenic mouse model of Alzheimer's disease. Brain Res Bull 56 (2001) 581-588
    • (2001) Brain Res Bull , vol.56 , pp. 581-588
    • Sly, L.M.1    Krzesicki, R.F.2    Brashler, J.R.3    Buhl, A.E.4    McKinley, D.D.5    Carter, D.B.6    Chin, J.E.7
  • 47
    • 3543025110 scopus 로고    scopus 로고
    • The association between delirium and cognitive decline: A review of the empirical literature
    • Jackson J.C., Gordon S.M., Hart R.P., Hopkins R.O., and Ely E.W. The association between delirium and cognitive decline: A review of the empirical literature. Neuropsychol Rev 14 (2004) 87-98
    • (2004) Neuropsychol Rev , vol.14 , pp. 87-98
    • Jackson, J.C.1    Gordon, S.M.2    Hart, R.P.3    Hopkins, R.O.4    Ely, E.W.5
  • 49
    • 14044279966 scopus 로고    scopus 로고
    • Toll-like receptor 4 on nonhematopoietic cells sustains CNS inflammation during endotoxemia, independent of systemic cytokines
    • Chakravarty S., and Herkenham M. Toll-like receptor 4 on nonhematopoietic cells sustains CNS inflammation during endotoxemia, independent of systemic cytokines. J Neurosci 25 (2005) 1788-1796
    • (2005) J Neurosci , vol.25 , pp. 1788-1796
    • Chakravarty, S.1    Herkenham, M.2
  • 50
    • 3543091441 scopus 로고    scopus 로고
    • How does peripheral lipopolysaccharide induce gene expression in the brain of rats?
    • Singh A.K., and Jiang Y. How does peripheral lipopolysaccharide induce gene expression in the brain of rats?. Toxicology 201 (2004) 197-207
    • (2004) Toxicology , vol.201 , pp. 197-207
    • Singh, A.K.1    Jiang, Y.2
  • 51
    • 46849088998 scopus 로고    scopus 로고
    • Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease
    • Godoy M.C., Tarelli R., Ferrari C.C., Sarchi M.I., and Pitossi F.J. Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease. Brain 131 Pt 7 (2008) 1880-1894
    • (2008) Brain , vol.131 , Issue.PART 7 , pp. 1880-1894
    • Godoy, M.C.1    Tarelli, R.2    Ferrari, C.C.3    Sarchi, M.I.4    Pitossi, F.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.