Preserved neuron number in the hippocampus of aged rats with spatial learning deficits

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 18, 1996, Pages 9926-9930

  Rapp, Peter R ^a   Gallagher, Michela ^b  

^a STONY BROOK UNIVERSITY   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

aging; memory; stereology

Indexed keywords

AGING; AMNESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COGNITIVE DEFECT; DENTATE GYRUS; HIPPOCAMPUS; LEARNING DISORDER; MALE; MAZE TEST; NERVE CELL DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SPATIAL MEMORY; STEREOLOGY;

AGING; ANIMALS; HIPPOCAMPUS; LEARNING DISORDERS; MAZE LEARNING; NEURONS; PHOTOMICROGRAPHY; RATS; SIGNAL PROCESSING, COMPUTER-ASSISTED;

EID: 0029821150     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.18.9926     Document Type: Article

References (25)

1. Coleman, P.D. & Flood, D. G. (1987) Neurobiol. Aging 8, 521-545.
2. Disterhoft, J. F., Moyer, J. R., Jr., & Thompson, L. T. (1994) Ann. N.Y. Acad. Sci. 747, 382-406.
3. Grady, C. L., McIntosh, A. R., Horwitz, B., Maisog, J. M., Ungerleider, L. G., Mentis, M. J., Pietrini, P., Schapiro, M. B. & Haxby, J. V. (1995) Science 269, 218-221.
4. Kerr, D. S., Campbell, L. W., Applegate, M. D., Brodish, A. & Landfield, P. W. (1991) J. Neurosci. 11, 1316-1324.
5. Landfield, P. W., Baskin, R. K. & Pitler,T. A. (1981) Science 214, 581-584.
6. Landfield, P. W. & Eldridge, J. C. (1994) Ann. N.Y. Acad. Sci. 747, 308-321.
7. McEwen, B. S. (1992) Prog. Brain Res. 93, 365-383.
8. Issa, A. M., Rowe, W., Gauthier, S. & Meaney, M. J. (1990) J. Neurosci. 10, 3247-3254.
9. Meaney, M. J., Aitken, D. H., van Berkel, C, Bhatnagar, S. & Sapolsky, R. M. (1988) Science 239, 766-768.
10. West, M. J. (1994) Semin. Neurosci. 6, 403-411.
11. Rapp, P. R., Burwell, R. D. & West, M. J. (1996) Neurobiol. Aging 17, 495-496.
12. Barnes, C. A. (1990) in Handbook of Neuropsychology, eds. Boller, F. & Grafman, J. (Elsevier, Amsterdam), Vol. 4, pp. 169-196.
13. Gage, F. H., Chen, K. S., Buzsaki, G. & Armstrong, D. (1988) Neurobiol. Aging 9, 645-655.
14. Gallagher, M., Nagahara, A. H. & Burwell, R. D. (1995) in Brain and Memory: Modulation and Mediation of Neuroplasticity, eds. McGaugh, J. L., Weinberger, N. & Lynch, G. (Oxford Univ. Press, New York), pp. 103-126.
15. Rapp, P. R. & Amaral, D. G. (1992) Trends Neurosci. 15, 340-345.
16. Morris, R. G. M., Garrud, P., Rawlins, J. N. P. & O'Keefe, J. (1982) Nature (London) 297, 681-683.
17. Gallagher, M., Burwell, R. D. & Burchinal, M. (1993) Behav. Neurosci. 107, 618-626.
18. West, M. J., Slomianka, L. & Gundersen, H. J. G. (1991) Anat. Rec. 231, 482-497.
19. Sterio, D. C. (1984) J. Microsc. (Oxford) 134, 127-136.
20. Rasmussen, T., Schliemann, T., Sørensen, J. C., Zimmer J & West, M. J. (1996) Neurobiol. Aging 17, 143-147.
21. Amaral, D. G., Ishizuka, N. & Claiborne, B. (1990) Prog Brain Res. 83, 1-11.
22. Patton, P. E. & McNaughton, B. (1995) Hippocampus 5, 245-286.
23. Gundersen, H. J. G. & Jensen, E. B. (1987) J. Microsc. (Oxford) 147, 229-263.
24. West, M. J. (1993) Neurobiol. Aging 14, 287-293.
25. West, M., Amaral, D. G. & Rapp, P. R. (1993) Soc. Neurosci. Abstr. 19, 59.