메뉴 건너뛰기




Volumn 14, Issue 2, 2015, Pages 239-250

MicroRNAs: Emerging role in the endogenous μ opioid system

Author keywords

Addiction; Fentanyl; MicroRNAs; Morphine; Mu opioid receptor; Opioids; Signal transduction; Tolerance

Indexed keywords

FENTANYL; MICRORNA; MICRORNA 103; MICRORNA 107; MICRORNA 125B; MICRORNA 128; MICRORNA 133B; MICRORNA 134; MICRORNA 150; MICRORNA 155; MICRORNA 15B; MICRORNA 181B; MICRORNA 184; MICRORNA 18A; MICRORNA 190; MICRORNA 20A; MICRORNA 224; MICRORNA 23B; MICRORNA 28; MICRORNA 301; MICRORNA 339; MICRORNA 365; MICRORNA 382; MICRORNA 410; MICRORNA 602; MICRORNA LET 7; MORPHINE; MU OPIATE RECEPTOR; PROTEIN VARIANT; UNCLASSIFIED DRUG; UNINDEXED DRUG; NARCOTIC ANALGESIC AGENT;

EID: 84930914304     PISSN: 18715273     EISSN: 19963181     Source Type: Journal    
DOI: 10.2174/1871527314666150116123932     Document Type: Article
Times cited : (31)

References (149)
  • 1
    • 0038162571 scopus 로고    scopus 로고
    • Opioids in Italy: Is marketing more powerful than the law?
    • Chinellato A, Terrazzani G, Walley T, Giusti P. Opioids in Italy: Is marketing more powerful than the law? Lancet 2003; 362: 78-80.
    • (2003) Lancet , vol.362 , pp. 78-80
    • Chinellato, A.1    Terrazzani, G.2    Walley, T.3    Giusti, P.4
  • 3
    • 84868648753 scopus 로고    scopus 로고
    • "Rethinking opioid prescribing to protect patient safety and public health"
    • Alexander GC, Kruszewski SP, Webster DW. "Rethinking opioid prescribing to protect patient safety and public health". J Am Med Assoc 2012; 308: 1865-6.
    • (2012) J Am Med Assoc , vol.308 , pp. 1865-1866
    • Alexander, G.C.1    Kruszewski, S.P.2    Webster, D.W.3
  • 5
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993; 75: 843-54.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 6
    • 33846283385 scopus 로고    scopus 로고
    • The evolution of gene regulation by transcription factors and microRNAs
    • Chen K, Rajewsky N. The evolution of gene regulation by transcription factors and microRNAs. Nat Rev Genet 2007; 8: 93- 103.
    • (2007) Nat Rev Genet , vol.8 , pp. 93-103
    • Chen, K.1    Rajewsky, N.2
  • 7
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell 2009; 136: 215-33.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 8
    • 77952840963 scopus 로고    scopus 로고
    • Microprocessor of microRNAs: Regulation and potential for therapeutic intervention
    • Beezhold KJ, Castranova V, Chen F. Microprocessor of microRNAs: regulation and potential for therapeutic intervention. Mol Cancer 2010; 9: 134.
    • (2010) Mol Cancer , vol.9 , pp. 134
    • Beezhold, K.J.1    Castranova, V.2    Chen, F.3
  • 9
    • 36749026906 scopus 로고    scopus 로고
    • Switching from repression to activation: MicroRNAs can up-regulate translation
    • Vasudevan S, Tong Y, Steitz JA. Switching from repression to activation: microRNAs can up-regulate translation. Science 2007; 318: 1931-4.
    • (2007) Science , vol.318 , pp. 1931-1934
    • Vasudevan, S.1    Tong, Y.2    Steitz, J.A.3
  • 10
    • 43449090367 scopus 로고    scopus 로고
    • MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation
    • Orom UA, Nielsen FC, Lund AH. MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation. Mol Cell 2008; 30: 460-71.
    • (2008) Mol Cell , vol.30 , pp. 460-471
    • Orom, U.A.1    Nielsen, F.C.2    Lund, A.H.3
  • 11
    • 22844440427 scopus 로고    scopus 로고
    • Identification of hundreds of conserved and nonconserved human microRNAs
    • Bentwich I, Avniel A, Karov Y, et al. Identification of hundreds of conserved and nonconserved human microRNAs. Nat Genet 2005; 37: 766-70.
    • (2005) Nat Genet , vol.37 , pp. 766-870
    • Bentwich, I.1    Avniel, A.2    Karov, Y.3
  • 12
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005; 120: 15-20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 13
  • 15
    • 0031874287 scopus 로고    scopus 로고
    • Recent advances in opioid pharmacology
    • Lambert DG. Recent advances in opioid pharmacology. Br J Anesthesiol 1998; 81: 1-2.
    • (1998) Br J Anesthesiol , vol.81 , pp. 1-2
    • Lambert, D.G.1
  • 16
    • 0028226886 scopus 로고
    • ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization
    • Mollereau C1, Parmentier M, Mailleux P, et al. ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization. FEBS Lett 1994; 341: 33-8.
    • (1994) FEBS Lett , vol.341 , pp. 33-38
    • Mollereau, C.1    Parmentier, M.2    Mailleux, P.3
  • 17
    • 0033821476 scopus 로고    scopus 로고
    • Tissue distribution of the opioid receptor-like (ORL1) receptor
    • Mollereau C, Mouledous L. Tissue distribution of the opioid receptor-like (ORL1) receptor. Peptides 2000; 21: 907-17.
    • (2000) Peptides , vol.21 , pp. 907-917
    • Mollereau, C.1    Mouledous, L.2
  • 18
    • 0027202213 scopus 로고
    • Molecular cloning and functional expression of a mu-opioid receptor from rat brain
    • Chen Y, Mestek A, Liu J, Hurley JA, Yu L. Molecular cloning and functional expression of a mu-opioid receptor from rat brain. Mol Pharmacol 1993; 44: 8-12.
    • (1993) Mol Pharmacol , vol.44 , pp. 8-12
    • Chen, Y.1    Mestek, A.2    Liu, J.3    Hurley, J.A.4    Yu, L.5
  • 19
    • 0027504836 scopus 로고
    • Cloning and pharmacological characterization of a rat mu opioid receptor
    • Thompson RC, Mansour A, Akil H, et al. Cloning and pharmacological characterization of a rat mu opioid receptor. Neuron 1993; 11: 903-13.
    • (1993) Neuron , vol.11 , pp. 903-913
    • Thompson, R.C.1    Mansour, A.2    Akil, H.3
  • 20
    • 0027441941 scopus 로고
    • Mu opiate receptor: CDNA cloning and expression
    • Wang JB, Imai Y, Eppler CM, et al. Mu opiate receptor: cDNA cloning and expression. Proc Natl Acad Sci USA 1993; 90: 10230-4.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10230-10234
    • Wang, J.B.1    Imai, Y.2    Eppler, C.M.3
  • 21
    • 0027369658 scopus 로고
    • Purification and partial amino acid sequence of a mu opioid receptor from rat brain
    • Eppler CM, Hulmes JD, Wang JB, et al. Purification and partial amino acid sequence of a mu opioid receptor from rat brain. J Biol Chem 1993; 268: 26447-51.
    • (1993) J Biol Chem , vol.268 , pp. 26447-26451
    • Eppler, C.M.1    Hulmes, J.D.2    Wang, J.B.3
  • 22
    • 0029852678 scopus 로고    scopus 로고
    • Loss of morphineinduced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene
    • Matthes HW, Maldonado R, Simonin F, et al. Loss of morphineinduced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene. Nature 1996; 383: 819-23.
    • (1996) Nature , vol.383 , pp. 819-823
    • Matthes, H.W.1    Maldonado, R.2    Simonin, F.3
  • 23
    • 0028089275 scopus 로고
    • Human mu opiate receptor. cDNA and genomic clones, pharmacologic characterization and chromosomal assignment
    • Wang JB, Johnson PS, Persico AM, Hawkins AL, Griffin CA, Uhl GR. Human mu opiate receptor. cDNA and genomic clones, pharmacologic characterization and chromosomal assignment. FEBS Lett 1994; 338: 217-22.
    • (1994) FEBS Lett , vol.338 , pp. 217-222
    • Wang, J.B.1    Johnson, P.S.2    Persico, A.M.3    Hawkins, A.L.4    Griffin, C.A.5    Uhl, G.R.6
  • 24
    • 61849086376 scopus 로고    scopus 로고
    • Expansion of the human muopioid receptor gene architecture: Novel functional variants
    • Shabalina SA, Zaykin DV, Gris P, et al. Expansion of the human muopioid receptor gene architecture: novel functional variants. Hum Mol Genet 2009; 18: 1037-51.
    • (2009) Hum Mol Genet , vol.18 , pp. 1037-1051
    • Shabalina, S.A.1    Zaykin, D.V.2    Gris, P.3
  • 26
    • 0028929251 scopus 로고
    • Chromosomal localization of opioid peptide and receptor genes in the mouse
    • Giros B, Pohl M, Rochelle JM, Seldin MF. Chromosomal localization of opioid peptide and receptor genes in the mouse. Life Sci 1995; 56: PL369-75.
    • (1995) Life Sci , vol.56 , pp. 369-375
    • Giros, B.1    Pohl, M.2    Rochelle, J.M.3    Seldin, M.F.4
  • 27
    • 0028946870 scopus 로고
    • Cloning and characterization of the promoter region of the mouse mu opioid receptor gene
    • Liang Y, Mestek A, Yu L, Carr LG. Cloning and characterization of the promoter region of the mouse mu opioid receptor gene. Brain Res 1995; 679: 82-8.
    • (1995) Brain Res , vol.679 , pp. 82-88
    • Liang, Y.1    Mestek, A.2    Yu, L.3    Carr, L.G.4
  • 28
    • 18844451788 scopus 로고    scopus 로고
    • Identification and characterization of six new alternatively spliced variants of the human mu opioid receptor gene, Oprm
    • Pan L, Xu J, Yu R, Xu MM, Pan YX, Pasternak GW. Identification and characterization of six new alternatively spliced variants of the human mu opioid receptor gene, Oprm. Neuroscience 2005; 133: 209-20.
    • (2005) Neuroscience , vol.133 , pp. 209-220
    • Pan, L.1    Xu, J.2    Yu, R.3    Xu, M.M.4    Pan, Y.X.5    Pasternak, G.W.6
  • 29
    • 84876675044 scopus 로고    scopus 로고
    • Mu opioids and their receptors: Evolution of a concept
    • Pasternak GW, Pan YX. Mu opioids and their receptors: Evolution of a concept. Pharmacol Rev 2013; 65: 1257-317.
    • (2013) Pharmacol Rev , vol.65 , pp. 1257-1317
    • Pasternak, G.W.1    Pan, Y.X.2
  • 30
    • 0034618846 scopus 로고    scopus 로고
    • Comparative immunohistochemical distributions of carboxy terminus epitopes from the mu-opioid receptor splice variants MOR-1D, MOR-1 and MOR-1C in the mouse and rat CNS
    • Abbadie C, Pan YX, Drake CT, Pasternak GW. Comparative immunohistochemical distributions of carboxy terminus epitopes from the mu-opioid receptor splice variants MOR-1D, MOR-1 and MOR-1C in the mouse and rat CNS. Neuroscience 2000; 100: 141- 53.
    • (2000) Neuroscience , vol.100 , pp. 141-153
    • Abbadie, C.1    Pan, Y.X.2    Drake, C.T.3    Pasternak, G.W.4
  • 31
    • 0034056705 scopus 로고    scopus 로고
    • Differential distribution in rat brain of mu opioid receptor carboxy terminal splice variants MOR- 1C-like and MOR-1-like immunoreactivity: Evidence for regionspecific processing
    • Abbadie C, Pan YX, Pasternak GW. Differential distribution in rat brain of mu opioid receptor carboxy terminal splice variants MOR- 1C-like and MOR-1-like immunoreactivity: Evidence for regionspecific processing. J Comp Neurol 2000; 419: 244-56.
    • (2000) J Comp Neurol , vol.419 , pp. 244-256
    • Abbadie, C.1    Pan, Y.X.2    Pasternak, G.W.3
  • 32
    • 0035923593 scopus 로고    scopus 로고
    • Generation of the mu opioid receptor (MOR-1) protein by three new splice variants of the Oprm gene
    • Pan YX, Xu A, Mahurter L, Bolan E, Xu MM, Pasternak GW. Generation of the mu opioid receptor (MOR-1) protein by three new splice variants of the Oprm gene. Proc Natl Acad Sci USA 2001; 98: 14084-9.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 14084-14089
    • Pan, Y.X.1    Xu, A.2    Mahurter, L.3    Bolan, E.4    Xu, M.M.5    Pasternak, G.W.6
  • 33
    • 0242580997 scopus 로고    scopus 로고
    • Functional analysis of MOR-1 splice variants of the mouse mu opioid receptor gene Oprm
    • Bolan EA, Pan YX, Pasternak GW. Functional analysis of MOR-1 splice variants of the mouse mu opioid receptor gene Oprm. Synapse 2004; 51: 11-18.
    • (2004) Synapse , vol.51 , pp. 11-18
    • Bolan, E.A.1    Pan, Y.X.2    Pasternak, G.W.3
  • 34
    • 23944518698 scopus 로고    scopus 로고
    • Identification of four novel exon 5 splice variants of the mouse muopioid receptor gene: Functional consequences of C-terminal splicing
    • Pan YX, Xu J, Bolan E, Moskowitz HS, Xu M, Pasternak GW. Identification of four novel exon 5 splice variants of the mouse muopioid receptor gene: functional consequences of C-terminal splicing. Mol Pharmacol 2005; 68: 866-75.
    • (2005) Mol Pharmacol , vol.68 , pp. 866-875
    • Pan, Y.X.1    Xu, J.2    Bolan, E.3    Moskowitz, H.S.4    Xu, M.5    Pasternak, G.W.6
  • 35
    • 0032577554 scopus 로고    scopus 로고
    • Carboxylterminal splicing of the rat mu opioid receptor modulates agonistmediated internalization and receptor resensitization
    • Koch T, Schulz S, Schroder H, Wolf R, Raulf E, Hollt V. Carboxylterminal splicing of the rat mu opioid receptor modulates agonistmediated internalization and receptor resensitization. J Biol Chem 1998; 273: 13652-7.
    • (1998) J Biol Chem , vol.273 , pp. 13652-13657
    • Koch, T.1    Schulz, S.2    Schroder, H.3    Wolf, R.4    Raulf, E.5    Hollt, V.6
  • 36
    • 0035903152 scopus 로고    scopus 로고
    • C-terminal splice variants of the mouse mu-opioid receptor differ in morphine-induced internalization and receptor resensitization
    • Koch T, Schulz S, Pfeiffer M, et al. C-terminal splice variants of the mouse mu-opioid receptor differ in morphine-induced internalization and receptor resensitization. J Biol Chem 2001; 276: 31408-14.
    • (2001) J Biol Chem , vol.276 , pp. 31408-31414
    • Koch, T.1    Schulz, S.2    Pfeiffer, M.3
  • 37
    • 58149093579 scopus 로고    scopus 로고
    • Alternative splicing determines the post-endocytic sorting fate of G-protein-coupled receptors
    • Tanowitz M, Hislop JN, von ZM. Alternative splicing determines the post-endocytic sorting fate of G-protein-coupled receptors. J Biol Chem 2008; 283: 35614-21.
    • (2008) J Biol Chem , vol.283 , pp. 35614-35621
    • Tanowitz, M.1    Hislop, J.N.2    von, Z.M.3
  • 38
    • 80054709876 scopus 로고    scopus 로고
    • Unidirectional cross-activation of GRPR by MOR1D uncouples itch and analgesia induced by opioids
    • Liu XY, Liu ZC, Sun YG, et al. Unidirectional cross-activation of GRPR by MOR1D uncouples itch and analgesia induced by opioids. Cell 2011; 147: 447-58.
    • (2011) Cell , vol.147 , pp. 447-458
    • Liu, X.Y.1    Liu, Z.C.2    Sun, Y.G.3
  • 39
    • 0037167168 scopus 로고    scopus 로고
    • Identification and characterization of a novel promoter of the mouse mu opioid receptor gene (Oprm) that generates eight splice variants
    • Pan YX. Identification and characterization of a novel promoter of the mouse mu opioid receptor gene (Oprm) that generates eight splice variants. Gene 2002; 295: 97-108.
    • (2002) Gene , vol.295 , pp. 97-108
    • Pan, Y.X.1
  • 40
    • 33845220086 scopus 로고    scopus 로고
    • Characterizing exons 11 and 1 promoters of the mu opioid receptor (Oprm) gene in transgenic mice
    • Xu J, Xu M, Pan YX. Characterizing exons 11 and 1 promoters of the mu opioid receptor (Oprm) gene in transgenic mice. BMC Mol Biol 2006; 7: 41.
    • (2006) BMC Mol Biol , vol.7 , pp. 41
    • Xu, J.1    Xu, M.2    Pan, Y.X.3
  • 41
    • 63849228557 scopus 로고    scopus 로고
    • Involvement of exon 11-associated variants of the mu opioid receptor MOR-1 in heroin, but not morphine, actions
    • Pan YX, Xu J, Xu M, Rossi GC, Matulonis JE, Pasternak GW. Involvement of exon 11-associated variants of the mu opioid receptor MOR-1 in heroin, but not morphine, actions. Proc Natl Acad Sci USA 2009; 106: 4917-22.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 4917-4922
    • Pan, Y.X.1    Xu, J.2    Xu, M.3    Rossi, G.C.4    Matulonis, J.E.5    Pasternak, G.W.6
  • 42
    • 83755177882 scopus 로고    scopus 로고
    • Truncated G proteincoupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects
    • Majumdar S, Grinnell S, Le R, et al. Truncated G proteincoupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects. Proc Natl Acad Sci USA 2011; 108: 19778-83.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 19778-19783
    • Majumdar, S.1    Grinnell, S.2    Le, R.3
  • 43
    • 84864220333 scopus 로고    scopus 로고
    • Synthesis and evaluation of arylnaloxamide opiate analgesics targeting truncated exon 11- associated mu opioid receptor (MOR-1) splice variants
    • Majumdar S, Subrath J, Le Rouzic V, et al. Synthesis and evaluation of arylnaloxamide opiate analgesics targeting truncated exon 11- associated mu opioid receptor (MOR-1) splice variants. J Med Chem 2012; 55: 6352-62.
    • (2012) J Med Chem , vol.55 , pp. 6352-6362
    • Majumdar, S.1    Subrath, J.2    Le Rouzic, V.3
  • 44
    • 84880533674 scopus 로고    scopus 로고
    • Stabilization of the μ-opioid receptor by truncated single transmembrane splice variants through a chaperonelike action
    • Xu J, Xu M, Brown T, et al. Stabilization of the μ-opioid receptor by truncated single transmembrane splice variants through a chaperonelike action. J Biol Chem 2013; 288: 21211-27.
    • (2013) J Biol Chem , vol.288 , pp. 21211-21227
    • Xu, J.1    Xu, M.2    Brown, T.3
  • 45
    • 0034128416 scopus 로고    scopus 로고
    • Molecular mechanisms and regulation of opioid receptor signaling
    • Law PY, Wong YH, Loh HH. Molecular mechanisms and regulation of opioid receptor signaling. Annu Rev Pharmacol Toxicol 2000; 40: 389-430.
    • (2000) Annu Rev Pharmacol Toxicol , vol.40 , pp. 389-430
    • Law, P.Y.1    Wong, Y.H.2    Loh, H.H.3
  • 46
    • 0035101820 scopus 로고    scopus 로고
    • Evolving concepts in G protein-coupled receptor endocytosis: The role in receptor desensitization and signaling
    • Ferguson SS. Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. Pharmacol Rev 2001; 53: 1-24.
    • (2001) Pharmacol Rev , vol.53 , pp. 1-24
    • Ferguson, S.S.1
  • 47
    • 0037452623 scopus 로고    scopus 로고
    • Desensitization, internalization, and signaling functions of betaarrestins demonstrated by RNA interference
    • Ahn S, Nelson CD, Garrison TR, Miller WE, Lefkowitz RJ. Desensitization, internalization, and signaling functions of betaarrestins demonstrated by RNA interference. Proc Natl Acad Sci USA 2003; 100: 1740-4.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 1740-1744
    • Ahn, S.1    Nelson, C.D.2    Garrison, T.R.3    Miller, W.E.4    Lefkowitz, R.J.5
  • 48
    • 0030593035 scopus 로고    scopus 로고
    • Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization
    • Ferguson SS, Downey WE 3rd, Colapietro AM, Barak LS, Ménard L, Caron MG. Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization. Science 1996; 271: 363-6.
    • (1996) Science , vol.271 , pp. 363-366
    • Ferguson, S.S.1    Downey, W.E.2    Colapietro, A.M.3    Barak, L.S.4    Ménard, L.5    Caron, M.G.6
  • 49
    • 84930278822 scopus 로고    scopus 로고
    • β-arrestins: Regulatory role and therapeutic potential in opioid and cannabinoid receptor-mediated analgesia
    • Raehal KM, Bohn LM. β-arrestins: regulatory role and therapeutic potential in opioid and cannabinoid receptor-mediated analgesia. Handb Exp Pharmacol 2014; 219: 427-43.
    • (2014) Handb Exp Pharmacol , vol.219 , pp. 427-443
    • Raehal, K.M.1    Bohn, L.M.2
  • 50
    • 0031975838 scopus 로고    scopus 로고
    • Essential role for G proteincoupled receptor endocytosis in the activation of mitogen-activated protein kinase
    • Daaka Y, Luttrell LM, Ahn S, et al. Essential role for G proteincoupled receptor endocytosis in the activation of mitogen-activated protein kinase. J Biol Chem 1998; 273: 685-8.
    • (1998) J Biol Chem , vol.273 , pp. 685-688
    • Daaka, Y.1    Luttrell, L.M.2    Ahn, S.3
  • 51
    • 0033613938 scopus 로고    scopus 로고
    • Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes
    • Luttrell LM, Ferguson SS, Daaka Y, et al. Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes. Science 1999; 283: 655-61.
    • (1999) Science , vol.283 , pp. 655-661
    • Luttrell, L.M.1    Ferguson, S.S.2    Daaka, Y.3
  • 52
    • 0034711397 scopus 로고    scopus 로고
    • Beta-arrestin 2: A receptor-regulated MAPK scaffold for the activation of JNK3
    • McDonald PH, Chow CW, Miller WE, et al. Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3. Science 2000; 290: 1574-7.
    • (2000) Science , vol.290 , pp. 1574-1577
    • McDonald, P.H.1    Chow, C.W.2    Miller, W.E.3
  • 53
    • 84958543696 scopus 로고    scopus 로고
    • Arrestin interactions with G protein-coupled receptors
    • Lohse MJ, Hoffmann C. Arrestin interactions with G protein-coupled receptors. Handb Exp Pharmacol 2014; 219: 15-56.
    • (2014) Handb Exp Pharmacol , vol.219 , pp. 15-56
    • Lohse, M.J.1    Hoffmann, C.2
  • 54
    • 22744449073 scopus 로고    scopus 로고
    • An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior
    • Beaulieu JM, Sotnikova TD, Marion S, Lefkowitz RJ, Gainetdinov RR, Caron MG. An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior. Cell 2005; 122: 261-73.
    • (2005) Cell , vol.122 , pp. 261-273
    • Beaulieu, J.M.1    Sotnikova, T.D.2    Marion, S.3    Lefkowitz, R.J.4    Gainetdinov, R.R.5    Caron, M.G.6
  • 55
    • 37649023273 scopus 로고    scopus 로고
    • A beta-arrestin 2 signaling complex mediates lithium action on behavior
    • Beaulieu JM, Marion S, Rodriguiz RM, et al. A beta-arrestin 2 signaling complex mediates lithium action on behavior. Cell 2008; 132: 125-33.
    • (2008) Cell , vol.132 , pp. 125-133
    • Beaulieu, J.M.1    Marion, S.2    Rodriguiz, R.M.3
  • 56
    • 60849127863 scopus 로고    scopus 로고
    • Physiological and pharmacological implications of beta-arrestin regulation
    • Schmid CL, Bohn LM. Physiological and pharmacological implications of beta-arrestin regulation. Pharmacol Ther 2009; 121: 285-93.
    • (2009) Pharmacol Ther , vol.121 , pp. 285-293
    • Schmid, C.L.1    Bohn, L.M.2
  • 57
    • 77957742904 scopus 로고    scopus 로고
    • Serotonin, but not N-methyltryptamines, activates the serotonin 2A receptor via a β-arrestin2/Src/Akt signaling complex in vivo
    • Schmid CL, Bohn LM. Serotonin, but not N-methyltryptamines, activates the serotonin 2A receptor via a β-arrestin2/Src/Akt signaling complex in vivo. J Neurosci 2020; 30: 13513-24.
    • (2020) J Neurosci , vol.30 , pp. 13513-13524
    • Schmid, C.L.1    Bohn, L.M.2
  • 58
    • 78651392735 scopus 로고    scopus 로고
    • A dopamine D1 receptor-dependent beta-arrestin signaling complex potentially regulates morphineinduced psychomotor activation but not reward in mice
    • Urs NM, Daigle TL, Caron MG. A dopamine D1 receptor-dependent beta-arrestin signaling complex potentially regulates morphineinduced psychomotor activation but not reward in mice. Neuropsychopharmacology 2010; 36: 551-8.
    • (2010) Neuropsychopharmacology , vol.36 , pp. 551-558
    • Urs, N.M.1    Daigle, T.L.2    Caron, M.G.3
  • 59
    • 78751498756 scopus 로고    scopus 로고
    • Functional selectivity and biased receptor signaling
    • Kenakin T. Functional selectivity and biased receptor signaling. J Pharmacol Exp Ther 2011; 336: 296-302.
    • (2011) J Pharmacol Exp Ther , vol.336 , pp. 296-302
    • Kenakin, T.1
  • 60
    • 27844519281 scopus 로고    scopus 로고
    • New concepts in drug discovery: Collateral efficacy and permissive antagonism
    • Kenakin T. New concepts in drug discovery: collateral efficacy and permissive antagonism. Nat Rev Drug Discov 2005; 4: 919-27.
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 919-927
    • Kenakin, T.1
  • 61
    • 34447624153 scopus 로고    scopus 로고
    • Collateral efficacy in drug discovery: Taking advantage of the good (allosteric) nature of 7TM receptors
    • Kenakin T. Collateral efficacy in drug discovery: taking advantage of the good (allosteric) nature of 7TM receptors. Trends Pharmacol Sci 2007; 28: 407-15.
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 407-415
    • Kenakin, T.1
  • 62
    • 34447626644 scopus 로고    scopus 로고
    • GPCR functional selectivity has therapeutic impact
    • Mailman RB. GPCR functional selectivity has therapeutic impact. Trends Pharmacol Sci 2007; 28: 390-6.
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 390-396
    • Mailman, R.B.1
  • 63
    • 33845903110 scopus 로고    scopus 로고
    • Functional selectivity and classical concepts of quantitative pharmacology
    • Urban JD, Clarke WP, von Zastrow M, et al. Functional selectivity and classical concepts of quantitative pharmacology. J Pharmacol Exp Ther 2007; 320: 1-13.
    • (2007) J Pharmacol Exp Ther , vol.320 , pp. 1-13
    • Urban, J.D.1    Clarke, W.P.2    von Zastrow, M.3
  • 64
    • 80053594753 scopus 로고    scopus 로고
    • Biased agonism F1000
    • Kenakin T. Biased agonism F1000. Biol Rep 2009; 1: 87.
    • (2009) Biol Rep , vol.1 , pp. 87
    • Kenakin, T.1
  • 65
    • 80053587249 scopus 로고    scopus 로고
    • Selectivity for G protein or arrestin-mediated signaling
    • Neve K, Ed. 1st ed. Totowa: Humana Press
    • Bohn LM. Selectivity for G protein or arrestin-mediated signaling. In: Neve K, Ed. Functional selectivity of G protein-coupled receptor ligands. 1st ed. Totowa: Humana Press 2009; pp. 71-85.
    • (2009) Functional selectivity of G protein-coupled receptor ligands. , pp. 71-85
    • Bohn, L.M.1
  • 66
    • 60849127863 scopus 로고    scopus 로고
    • Physiological and pharmacological implications of beta-arrestin regulation
    • Schmid CL, Bohn LM. Physiological and pharmacological implications of beta-arrestin regulation. Pharmacol Ther 2009; 121: 285-93.
    • (2009) Pharmacol Ther , vol.121 , pp. 285-293
    • Schmid, C.L.1    Bohn, L.M.2
  • 67
    • 84875469202 scopus 로고    scopus 로고
    • Recent developments in the study of opioid receptors
    • Cox BM. Recent developments in the study of opioid receptors. Mol Pharmacol 2013; 83: 723-8.
    • (2013) Mol Pharmacol , vol.83 , pp. 723-728
    • Cox, B.M.1
  • 68
    • 84874936352 scopus 로고    scopus 로고
    • Ligand interaction, binding site and G protein activation of the mu opioid receptor
    • Cui X, Yeliseev A, Liu R. Ligand interaction, binding site and G protein activation of the mu opioid receptor. Eur J Pharmacol 2013; 702: 309-15.
    • (2013) Eur J Pharmacol , vol.702 , pp. 309-315
    • Cui, X.1    Yeliseev, A.2    Liu, R.3
  • 69
    • 0031018574 scopus 로고    scopus 로고
    • Transdermal fentanyl. A review of its pharmacological properties and therapeutic efficacy in pain control
    • Jeal W, Benfield P. Transdermal fentanyl. A review of its pharmacological properties and therapeutic efficacy in pain control. Drugs 1997; 53: 109-38.
    • (1997) Drugs , vol.53 , pp. 109-138
    • Jeal, W.1    Benfield, P.2
  • 70
    • 48249112969 scopus 로고    scopus 로고
    • Opioids and the management of chronic severe pain in the elderly: Consensus statement of an International Expert Panel with focus on the six clinically most often used World Health Organization Step III opioids (buprenorphine, fentanyl, hydromorphone, methadone, morphine, oxycodone)
    • Pergolizzi J, Böger RH, Budd K, et al. Opioids and the management of chronic severe pain in the elderly: consensus statement of an International Expert Panel with focus on the six clinically most often used World Health Organization Step III opioids (buprenorphine, fentanyl, hydromorphone, methadone, morphine, oxycodone). Pain Pract 2008; 8: 287-313.
    • (2008) Pain Pract , vol.8 , pp. 287-313
    • Pergolizzi, J.1    Böger, R.H.2    Budd, K.3
  • 71
    • 0029040497 scopus 로고
    • The effect of intrinsic efficacy on opioid tolerance
    • Duttaroy A, Yoburn BC. The effect of intrinsic efficacy on opioid tolerance. Anesthesiology 1995; 82: 1226-36.
    • (1995) Anesthesiology , vol.82 , pp. 1226-1236
    • Duttaroy, A.1    Yoburn, B.C.2
  • 72
    • 73449149275 scopus 로고    scopus 로고
    • μ-Opioid receptor agonists differentially regulate the expression of miR-190 and NeuroD
    • Zheng H, Zeng Y, Zhang X, Chu J, Loh HH, Law PY. μ-Opioid receptor agonists differentially regulate the expression of miR-190 and NeuroD. Mol Pharmacol 2010; 77: 102-9.
    • (2010) Mol Pharmacol , vol.77 , pp. 102-109
    • Zheng, H.1    Zeng, Y.2    Zhang, X.3    Chu, J.4    Loh, H.H.5    Law, P.Y.6
  • 73
    • 77954618593 scopus 로고    scopus 로고
    • Yin Yang 1 phosphorylation contributes to the differential effects of mu-opioid receptor agonists on microRNA-190 expression
    • Zheng H, Chu J, Zeng Y, Loh HH, Law PY. Yin Yang 1 phosphorylation contributes to the differential effects of mu-opioid receptor agonists on microRNA-190 expression. J Biol Chem 2010; 285: 21994-2002.
    • (2010) J Biol Chem , vol.285 , pp. 21994-22002
    • Zheng, H.1    Chu, J.2    Zeng, Y.3    Loh, H.H.4    Law, P.Y.5
  • 74
    • 84871294542 scopus 로고    scopus 로고
    • δ-opioid receptor activation and microRNA expression of the rat cortex in hypoxia
    • Yang Y, Zhi F, He X, et al. δ-opioid receptor activation and microRNA expression of the rat cortex in hypoxia. PLoS One 2012; 7: 12.
    • (2012) PLoS One , vol.7 , pp. 12
    • Yang, Y.1    Zhi, F.2    He, X.3
  • 75
    • 84876186131 scopus 로고    scopus 로고
    • δ-Opioid receptor activation modified microRNA expression in the rat kidney under prolonged hypoxia
    • He X, Yang Y, Zhi F, et al. δ-Opioid receptor activation modified microRNA expression in the rat kidney under prolonged hypoxia. PLoS One 2013; 8:4.
    • (2013) PLoS One , vol.8 , pp. 4
    • He, X.1    Yang, Y.2    Zhi, F.3
  • 76
    • 57349165971 scopus 로고    scopus 로고
    • Post-transcriptional regulation of mouse mu opioid receptor (MOR1) via its 3′ untranslated region: A role for microRNA23b
    • Wu Q, Law PY, Wei LN, Loh HH. Post-transcriptional regulation of mouse mu opioid receptor (MOR1) via its 3′ untranslated region: a role for microRNA23b. FASEB J 2008; 22: 4085-95.
    • (2008) FASEB J , vol.22 , pp. 4085-4095
    • Wu, Q.1    Law, P.Y.2    Wei, L.N.3    Loh, H.H.4
  • 77
    • 63849224120 scopus 로고    scopus 로고
    • Long-term morphine treatment decreases the association of mu-opioid receptor (MOR1) mRNA with polysomes through miRNA23b
    • Wu Q, Zhang L, Law PY, Wei LN, Loh HH. Long-term morphine treatment decreases the association of mu-opioid receptor (MOR1) mRNA with polysomes through miRNA23b. Mol Pharmacol 2009; 75: 744-750.
    • (2009) Mol Pharmacol , vol.75 , pp. 744-750
    • Wu, Q.1    Zhang, L.2    Law, P.Y.3    Wei, L.N.4    Loh, H.H.5
  • 79
    • 77954108034 scopus 로고    scopus 로고
    • Morphine treatment of human monocyte-derived macrophages induces differential miRNA and protein expression: Impact on inflammation and oxidative stress in the central nervous system
    • Dave RS, Khalili K. Morphine treatment of human monocyte-derived macrophages induces differential miRNA and protein expression: impact on inflammation and oxidative stress in the central nervous system. J Cell Biochem 2010; 110: 834-45.
    • (2010) J Cell Biochem , vol.110 , pp. 834-845
    • Dave, R.S.1    Khalili, K.2
  • 80
    • 77955371740 scopus 로고    scopus 로고
    • Regulation of opioid tolerance by let-7 family microRNA targeting the mu opioid receptor
    • He Y, Yang C, Kirkmire CM, Wang ZJ. Regulation of opioid tolerance by let-7 family microRNA targeting the mu opioid receptor. J Neurosci 2010; 30: 10251-8.
    • (2010) J Neurosci , vol.30 , pp. 10251-10258
    • He, Y.1    Yang, C.2    Kirkmire, C.M.3    Wang, Z.J.4
  • 81
    • 84891879239 scopus 로고    scopus 로고
    • Morphine regulates expression of μ-opioid receptor MOR-1A, an intron-retention carboxyl terminal splice variant of the μ-opioid receptor (OPRM1) gene via miR-103/miR-107
    • Lu Z, Xu J, Xu M, Pasternak GW, Pan YX. Morphine regulates expression of μ-opioid receptor MOR-1A, an intron-retention carboxyl terminal splice variant of the μ-opioid receptor (OPRM1) gene via miR-103/miR-107. Mol Pharmacol 2014; 85: 368-80.
    • (2014) Mol Pharmacol , vol.85 , pp. 368-380
    • Lu, Z.1    Xu, J.2    Xu, M.3    Pasternak, G.W.4    Pan, Y.X.5
  • 82
    • 84873468505 scopus 로고    scopus 로고
    • MicroRNA 339 down-regulates μ-opioid receptor at the post-transcriptional level in response to opioid treatment
    • Wu Q, Hwang CK, Zheng H, et al. MicroRNA 339 down-regulates μ-opioid receptor at the post-transcriptional level in response to opioid treatment. FASEB J 2013; 27: 522-35.
    • (2013) FASEB J , vol.27 , pp. 522-535
    • Wu, Q.1    Hwang, C.K.2    Zheng, H.3
  • 83
    • 84893434680 scopus 로고    scopus 로고
    • Morphine modulates cell proliferation through mir133b &mir128 in the neuroblastoma SH-SY5Y cell line
    • Gonzalez-Nunez V, Noriega-Prieto JA, Rodríguez RE. Morphine modulates cell proliferation through mir133b &mir128 in the neuroblastoma SH-SY5Y cell line. Biochim Biophys Acta 2014; 1842: 566-72.
    • (2014) Biochim Biophys Acta , vol.1842 , pp. 566-572
    • Gonzalez-Nunez, V.1    Noriega-Prieto, J.A.2    Rodríguez, R.E.3
  • 84
    • 28844505148 scopus 로고    scopus 로고
    • Characterization of the 3' untranslated region of the human mu-opioid receptor (MOR-1) mRNA
    • Ide S, Han W, Kasai S, Hata H, Sora I, Ikeda K. Characterization of the 3' untranslated region of the human mu-opioid receptor (MOR-1) mRNA. Gene 2005; 364: 139-45.
    • (2005) Gene , vol.364 , pp. 139-145
    • Ide, S.1    Han, W.2    Kasai, S.3    Hata, H.4    Sora, I.5    Ikeda, K.6
  • 85
    • 33744462848 scopus 로고    scopus 로고
    • Intracisternal A-particle element in the 3' noncoding region of the mu-opioid receptor gene in CXBK mice: A new genetic mechanism underlying differences in opioid sensitivity
    • Han W, Kasai S, Hata H, et al. Intracisternal A-particle element in the 3' noncoding region of the mu-opioid receptor gene in CXBK mice: a new genetic mechanism underlying differences in opioid sensitivity. Pharmacogenet Genom 2006; 16: 451-60.
    • (2006) Pharmacogenet Genom , vol.16 , pp. 451-460
    • Han, W.1    Kasai, S.2    Hata, H.3
  • 86
    • 0342323732 scopus 로고    scopus 로고
    • Control of mu opioid receptor expression by modification of cDNA 5'- and 3'-noncoding regions
    • Zöllner C, Johnson PS, Bei Wang J, et al. Control of mu opioid receptor expression by modification of cDNA 5'- and 3'-noncoding regions. Brain Res Mol Brain Res 2000; 79: 159-62.
    • (2000) Brain Res Mol Brain Res , vol.79 , pp. 159-162
    • Zöllner, C.1    Johnson, P.S.2    Bei Wang, J.3
  • 87
    • 22144469473 scopus 로고    scopus 로고
    • Internal tandem duplications of the FLT3 gene are present in leukemia stem cells
    • Levis M, Murphy KM, Pham R, et al. Internal tandem duplications of the FLT3 gene are present in leukemia stem cells. Blood 2005; 106: 673-80.
    • (2005) Blood , vol.106 , pp. 673-680
    • Levis, M.1    Murphy, K.M.2    Pham, R.3
  • 88
    • 69749105831 scopus 로고    scopus 로고
    • Altered microRNA expression following traumatic spinal cord injury
    • Liu NK, Wang XF, Lu QB, Xu XM. Altered microRNA expression following traumatic spinal cord injury. Exp Neurol 2009; 219: 424-9.
    • (2009) Exp Neurol , vol.219 , pp. 424-429
    • Liu, N.K.1    Wang, X.F.2    Lu, Q.B.3    Xu, X.M.4
  • 89
    • 84879366404 scopus 로고    scopus 로고
    • Regulation of μ- opioid type 1 receptors by microRNA134 in dorsal root ganglion neurons following peripheral inflammation
    • Ni J, Gao Y, Gong S, Guo S, Hisamitsu T, Jiang X. Regulation of μ- opioid type 1 receptors by microRNA134 in dorsal root ganglion neurons following peripheral inflammation. Eur J Pain 2013; 17: 313- 23.
    • (2013) Eur J Pain , vol.17 , pp. 313-323
    • Ni, J.1    Gao, Y.2    Gong, S.3    Guo, S.4    Hisamitsu, T.5    Jiang, X.6
  • 91
    • 1542358989 scopus 로고    scopus 로고
    • Molecular neurobiology of drug addiction
    • Chao J, Nestler EJ. Molecular neurobiology of drug addiction. Annu Rev Med 2004; 55: 113-32.
    • (2004) Annu Rev Med , vol.55 , pp. 113-132
    • Chao, J.1    Nestler, E.J.2
  • 92
    • 33645109259 scopus 로고    scopus 로고
    • Opiates, psychostimulants, and adult hippocampal neurogenesis: Insights for addiction and stem cell biology
    • Eisch AJ, Harburg GC. Opiates, psychostimulants, and adult hippocampal neurogenesis: insights for addiction and stem cell biology. Hippocampus 2006; 16: 271-86.
    • (2006) Hippocampus , vol.16 , pp. 271-286
    • Eisch, A.J.1    Harburg, G.C.2
  • 94
    • 84875228547 scopus 로고    scopus 로고
    • NeuroD modulates opioid agonist-selective regulation of adult neurogenesis and contextual memory extinction
    • Zheng H, Zhang Y, Li W, Loh HH, Law PY. NeuroD modulates opioid agonist-selective regulation of adult neurogenesis and contextual memory extinction. Neuropsychopharmacology 2013; 38: 770-7.
    • (2013) Neuropsychopharmacology , vol.38 , pp. 770-777
    • Zheng, H.1    Zhang, Y.2    Li, W.3    Loh, H.H.4    Law, P.Y.5
  • 95
    • 84873502431 scopus 로고    scopus 로고
    • Morphine and microRNA Activity: Is there a relation with addiction?
    • Rodriguez RE. Morphine and microRNA Activity: Is there a relation with addiction? Front Genet 2012; 3: 223.
    • (2012) Front Genet , vol.3 , pp. 223
    • Rodriguez, R.E.1
  • 96
    • 37349016848 scopus 로고    scopus 로고
    • Synaptic plasticity, memory and the hippocampus: A neural network approach to causality
    • Neves G, Cooke SF, Bliss TV. Synaptic plasticity, memory and the hippocampus: a neural network approach to causality. Nat Rev Neurosci 2008; 9: 65-75.
    • (2008) Nat Rev Neurosci , vol.9 , pp. 65-75
    • Neves, G.1    Cooke, S.F.2    Bliss, T.V.3
  • 97
    • 67649360001 scopus 로고    scopus 로고
    • The formation of recent and remote memory is associated with timedependent formation of dendritic spines in the hippocampus and anterior cingulate cortex
    • Restivo L, Vetere G, Bontempi B, Ammassari-Teule M. The formation of recent and remote memory is associated with timedependent formation of dendritic spines in the hippocampus and anterior cingulate cortex. J Neurosci 2009; 29: 8206-14.
    • (2009) J Neurosci , vol.29 , pp. 8206-8214
    • Restivo, L.1    Vetere, G.2    Bontempi, B.3    Ammassari-Teule, M.4
  • 98
    • 0033039909 scopus 로고    scopus 로고
    • Inhibition of calcium/calmodulin-dependent protein kinase II in rat hippocampus attenuates morphine tolerance and dependence
    • Fan GH, Wang LZ, Qiu HC, Ma L, Pei G. Inhibition of calcium/calmodulin-dependent protein kinase II in rat hippocampus attenuates morphine tolerance and dependence. Mol Pharmacol 1999; 56: 39-45.
    • (1999) Mol Pharmacol , vol.56 , pp. 39-45
    • Fan, G.H.1    Wang, L.Z.2    Qiu, H.C.3    Ma, L.4    Pei, G.5
  • 99
    • 33644994837 scopus 로고    scopus 로고
    • Persistent disruption of an established morphine conditioned place preference
    • Milekic MH, Brown SD, Castellini C, Alberini CM. Persistent disruption of an established morphine conditioned place preference. J Neurosci 2006; 26: 3010-20.
    • (2006) J Neurosci , vol.26 , pp. 3010-3020
    • Milekic, M.H.1    Brown, S.D.2    Castellini, C.3    Alberini, C.M.4
  • 100
    • 51749092861 scopus 로고    scopus 로고
    • Chronic, but not acute morphine treatment, up-regulates alpha-Ca2+/calmodulin dependent protein kinase II gene expression in rat brain
    • Chen Y, Jiang Y, Yue W, Zhou Y, Lu L, Ma L. Chronic, but not acute morphine treatment, up-regulates alpha-Ca2+/calmodulin dependent protein kinase II gene expression in rat brain. Neurochem Res 2008; 33: 2092-8.
    • (2008) Neurochem Res , vol.33 , pp. 2092-2098
    • Chen, Y.1    Jiang, Y.2    Yue, W.3    Zhou, Y.4    Lu, L.5    Ma, L.6
  • 101
    • 37149010976 scopus 로고    scopus 로고
    • Neurogenin and NeuroD direct transcriptional targets and their regulatory enhancers
    • Seo S, Lim JW, Yellajoshyula D, Chang LW, Kroll KL. Neurogenin and NeuroD direct transcriptional targets and their regulatory enhancers. EMBO J 2007; 26: 5093-108.
    • (2007) EMBO J , vol.26 , pp. 5093-5108
    • Seo, S.1    Lim, J.W.2    Yellajoshyula, D.3    Chang, L.W.4    Kroll, K.L.5
  • 102
    • 77953773592 scopus 로고    scopus 로고
    • Modulations of NeuroD activity contribute to the differential effects of morphine and fentanyl on dendritic spine stability
    • Zheng H, Zeng Y, Chu J, Kam AY, Loh HH, Law PY. Modulations of NeuroD activity contribute to the differential effects of morphine and fentanyl on dendritic spine stability. J Neurosci 2010; 30: 8102- 10.
    • (2010) J Neurosci , vol.30 , pp. 8102-8110
    • Zheng, H.1    Zeng, Y.2    Chu, J.3    Kam, A.Y.4    Loh, H.H.5    Law, P.Y.6
  • 103
    • 33845928958 scopus 로고    scopus 로고
    • Mu- and kappa-opioids induce the differentiation of embryonic stem cells to neural progenitors
    • Kim E, Clark AL, Kiss A, et al. Mu- and kappa-opioids induce the differentiation of embryonic stem cells to neural progenitors. J Biol Chem 2006; 281: 33749-60.
    • (2006) J Biol Chem , vol.281 , pp. 33749-33760
    • Kim, E.1    Clark, A.L.2    Kiss, A.3
  • 104
    • 70350440311 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase 1/2 activation counteracts morphine tolerance in the periaqueductal gray of the rat
    • Macey TA, Bobeck EN, Hegarty DM, Aicher SA, Ingram SL, Morgan MM. Extracellular signal-regulated kinase 1/2 activation counteracts morphine tolerance in the periaqueductal gray of the rat. J Pharmacol Exp Ther 2009; 331: 412-8.
    • (2009) J Pharmacol Exp Ther , vol.331 , pp. 412-418
    • Macey, T.A.1    Bobeck, E.N.2    Hegarty, D.M.3    Aicher, S.A.4    Ingram, S.L.5    Morgan, M.M.6
  • 105
    • 77954510708 scopus 로고    scopus 로고
    • Striatal microRNA controls cocaine intake through CREB signalling
    • Hollander JA, Im HI, Amelio AL, et al. Striatal microRNA controls cocaine intake through CREB signalling. Nature 2010; 466: 197-202.
    • (2010) Nature , vol.466 , pp. 197-202
    • Hollander, J.A.1    Im, H.I.2    Amelio, A.L.3
  • 106
    • 78751696179 scopus 로고    scopus 로고
    • New insights into the roles of microRNAs in drug addiction and neuroplasticity
    • Dreyer JL. New insights into the roles of microRNAs in drug addiction and neuroplasticity. Genome Med 2010; 2: 92.
    • (2010) Genome Med , vol.2 , pp. 92
    • Dreyer, J.L.1
  • 107
    • 77956252381 scopus 로고    scopus 로고
    • Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction
    • Schaefer A, Im HI, Venø MT, et al. Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction. J Exp Med 2010; 207: 1843-51.
    • (2010) J Exp Med , vol.207 , pp. 1843-1851
    • Schaefer, A.1    Im, H.I.2    Venø, M.T.3
  • 108
    • 79251506965 scopus 로고    scopus 로고
    • Inhibition of anti-HIV microRNA expression: A mechanism for opioid-mediated enhancement of HIV infection of monocytes
    • Wang X, Ye L, Zhou Y, Liu MQ, Zhou DJ, Ho WZ. Inhibition of anti-HIV microRNA expression: a mechanism for opioid-mediated enhancement of HIV infection of monocytes. Am J Pathol 2011; 178: 41-7.
    • (2011) Am J Pathol , vol.178 , pp. 41-47
    • Wang, X.1    Ye, L.2    Zhou, Y.3    Liu, M.Q.4    Zhou, D.J.5    Ho, W.Z.6
  • 109
    • 33747461037 scopus 로고    scopus 로고
    • Neurobiology of multiple insults: HIV-1-associated brain disorders in those who use illicit drugs
    • Bell JE, Arango JC, Anthony IC. Neurobiology of multiple insults: HIV-1-associated brain disorders in those who use illicit drugs. J Neuroimmune Pharmacol 2006; 1: 182-91.
    • (2006) J Neuroimmune Pharmacol , vol.1 , pp. 182-191
    • Bell, J.E.1    Arango, J.C.2    Anthony, I.C.3
  • 110
    • 77956544206 scopus 로고    scopus 로고
    • Interactive comorbidity between opioid drug abuse and HIV-1 Tat: Chronic exposure augments spine loss and sublethal dendritic pathology in striatal neurons
    • Fitting S, Xu R, Bull C, et al. Interactive comorbidity between opioid drug abuse and HIV-1 Tat: chronic exposure augments spine loss and sublethal dendritic pathology in striatal neurons. Am J Pathol 2010; 177: 1397-410.
    • (2010) Am J Pathol , vol.177 , pp. 1397-1410
    • Fitting, S.1    Xu, R.2    Bull, C.3
  • 112
    • 33846245892 scopus 로고    scopus 로고
    • HIV-1 neuropathogenesis: Glial mechanisms revealed through substance abuse
    • Hauser KF, El-Hage N, Stiene-Martin A, et al. HIV-1 neuropathogenesis: glial mechanisms revealed through substance abuse. J Neurochem 2007; 100: 567-86.
    • (2007) J Neurochem , vol.100 , pp. 567-586
    • Hauser, K.F.1    El-Hage, N.2    Stiene-Martin, A.3
  • 113
    • 0033989648 scopus 로고    scopus 로고
    • Functional interactions between C/EBP, Sp1, and COUP-TF regulate human immunodeficiency virus type 1 gene transcription in human brain cells
    • Schwartz C, Catez P, Rohr O, Lecestre D, Aunis D, Schaeffer E. Functional interactions between C/EBP, Sp1, and COUP-TF regulate human immunodeficiency virus type 1 gene transcription in human brain cells. J Virol 2000; 74: 65-73.
    • (2000) J Virol , vol.74 , pp. 65-73
    • Schwartz, C.1    Catez, P.2    Rohr, O.3    Lecestre, D.4    Aunis, D.5    Schaeffer, E.6
  • 114
    • 33845485288 scopus 로고    scopus 로고
    • Reconstitution of human immunodeficiency virus-induced neurodegeneration using isolated populations of human neurons, astrocytes, and microglia and neuroprotection mediated by insulin-like growth factors
    • Wang J, Gabuzda D. Reconstitution of human immunodeficiency virus-induced neurodegeneration using isolated populations of human neurons, astrocytes, and microglia and neuroprotection mediated by insulin-like growth factors. J Neurovirol 2006; 12: 472-91.
    • (2006) J Neurovirol , vol.12 , pp. 472-491
    • Wang, J.1    Gabuzda, D.2
  • 115
    • 60249083292 scopus 로고    scopus 로고
    • Cellular microRNA expression correlates with susceptibility of monocytes/macrophages to HIV-1 infection
    • Wang X, Ye L, Hou W, et al. Cellular microRNA expression correlates with susceptibility of monocytes/macrophages to HIV-1 infection. Blood 2009; 113: 671-4.
    • (2009) Blood , vol.113 , pp. 671-674
    • Wang, X.1    Ye, L.2    Hou, W.3
  • 116
    • 23944516870 scopus 로고    scopus 로고
    • The host type I interferon response to viral and bacterial infections
    • Perry AK, Chen G, Zheng D, Tang H, Cheng G. The host type I interferon response to viral and bacterial infections. Cell Res 2005; 15: 407-22.
    • (2005) Cell Res , vol.15 , pp. 407-422
    • Perry, A.K.1    Chen, G.2    Zheng, D.3    Tang, H.4    Cheng, G.5
  • 119
    • 35349009932 scopus 로고    scopus 로고
    • Interferon modulation of cellular microRNAs as an antiviral mechanism
    • Pedersen IM, Cheng G, Wieland S, et al. Interferon modulation of cellular microRNAs as an antiviral mechanism. Nature 2007; 449: 919-22.
    • (2007) Nature , vol.449 , pp. 919-922
    • Pedersen, I.M.1    Cheng, G.2    Wieland, S.3
  • 120
    • 73849126052 scopus 로고    scopus 로고
    • The modulation of microRNAs by type I IFN through the activation of signal transducers and activators of transcription 3 in human glioma
    • Ohno M, Natsume A, Kondo Y, et al. The modulation of microRNAs by type I IFN through the activation of signal transducers and activators of transcription 3 in human glioma. Mol Cancer Res 2009; 7: 2022-30.
    • (2009) Mol Cancer Res , vol.7 , pp. 2022-2030
    • Ohno, M.1    Natsume, A.2    Kondo, Y.3
  • 122
    • 0036570920 scopus 로고    scopus 로고
    • Inhibition of morphine-potentiated HIV-1 replication in peripheral blood mononuclear cells with the nuclease-resistant 2-5A agonist analog, 2- 5A(N6B)
    • Homan JW, Steele AD, Martinand-Mari C, et al. Inhibition of morphine-potentiated HIV-1 replication in peripheral blood mononuclear cells with the nuclease-resistant 2-5A agonist analog, 2- 5A(N6B). J Acquir Immune Defic Syndr 2002; 30: 9-20.
    • (2002) J Acquir Immune Defic Syndr , vol.30 , pp. 9-20
    • Homan, J.W.1    Steele, A.D.2    Martinand-Mari, C.3
  • 123
    • 0032520696 scopus 로고    scopus 로고
    • Opiates as potential cofactors in progression of HIV-1 infections to AIDS
    • Donahoe RM, Vlahov D. Opiates as potential cofactors in progression of HIV-1 infections to AIDS. J Neuroimmunol 1998; 83: 77-87.
    • (1998) J Neuroimmunol , vol.83 , pp. 77-87
    • Donahoe, R.M.1    Vlahov, D.2
  • 124
  • 125
    • 0031901134 scopus 로고    scopus 로고
    • Expression of CCR5 increases during monocyte differentiation and directly mediates macrophage susceptibility to infection by human immunodeficiency virus type 1
    • Tuttle DL, Harrison JK, Anders C, Sleasman JW, Goodenow MM. Expression of CCR5 increases during monocyte differentiation and directly mediates macrophage susceptibility to infection by human immunodeficiency virus type 1. J Virol 1998; 72: 4962-9.
    • (1998) J Virol , vol.72 , pp. 4962-4969
    • Tuttle, D.L.1    Harrison, J.K.2    Anders, C.3    Sleasman, J.W.4    Goodenow, M.M.5
  • 126
    • 42549113127 scopus 로고    scopus 로고
    • HIV-1 variation before seroconversion in men who have sex with men: Analysis of acute/early HIV infection in the multicenter AIDS cohort study
    • Gottlieb GS, Heath L, Nickle DC, et al. HIV-1 variation before seroconversion in men who have sex with men: analysis of acute/early HIV infection in the multicenter AIDS cohort study. J Infect Dis 2008; 197: 1011-5.
    • (2008) J Infect Dis , vol.197 , pp. 1011-1015
    • Gottlieb, G.S.1    Heath, L.2    Nickle, D.C.3
  • 127
    • 44649102135 scopus 로고    scopus 로고
    • Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection
    • Keele BF, Giorgi EE, Salazar-Gonzalez JF, et al. Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. Proc Natl Acad Sci USA 2008; 105: 7552- 7.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 7552-7557
    • Keele, B.F.1    Giorgi, E.E.2    Salazar-Gonzalez, J.F.3
  • 128
    • 0036840219 scopus 로고    scopus 로고
    • Morphine enhances HIV infection of human blood mononuclear phagocytes through modulation of beta-chemokines and CCR5 receptor
    • Guo CJ, Li Y, Tian S, Wang X, Douglas SD, Ho WZ. Morphine enhances HIV infection of human blood mononuclear phagocytes through modulation of beta-chemokines and CCR5 receptor. J Investig Med 2002; 50: 435-42.
    • (2002) J Investig Med , vol.50 , pp. 435-442
    • Guo, C.J.1    Li, Y.2    Tian, S.3    Wang, X.4    Douglas, S.D.5    Ho, W.Z.6
  • 129
    • 0036138197 scopus 로고    scopus 로고
    • Methadone enhances human immunodeficiency virus infection of human immune cells
    • Li Y, Wang X, Tian S, Guo CJ, Douglas SD, Ho WZ. Methadone enhances human immunodeficiency virus infection of human immune cells. J Infect Dis 2002; 185: 118-22.
    • (2002) J Infect Dis , vol.185 , pp. 118-122
    • Li, Y.1    Wang, X.2    Tian, S.3    Guo, C.J.4    Douglas, S.D.5    Ho, W.Z.6
  • 130
    • 0344304773 scopus 로고    scopus 로고
    • Methylnaltrexone antagonizes opioid-mediated enhancement of HIV infection of human blood mononuclear phagocytes
    • Ho WZ, Guo CJ, Yuan CS, Douglas SD, Moss J. Methylnaltrexone antagonizes opioid-mediated enhancement of HIV infection of human blood mononuclear phagocytes. J Pharmacol Exp Ther 2003; 307: 1158-62.
    • (2003) J Pharmacol Exp Ther , vol.307 , pp. 1158-1162
    • Ho, W.Z.1    Guo, C.J.2    Yuan, C.S.3    Douglas, S.D.4    Moss, J.5
  • 131
    • 33846418330 scopus 로고    scopus 로고
    • Hepatitis C virus eradication in intravenous drug users maintained with subcutaneous naltrexone implants
    • Jeffrey GP, MacQuillan G, Chua F, et al. Hepatitis C virus eradication in intravenous drug users maintained with subcutaneous naltrexone implants. Hepatology 2007; 45: 111-7.
    • (2007) Hepatology , vol.45 , pp. 111-117
    • Jeffrey, G.P.1    McQuillan, G.2    Chua, F.3
  • 132
    • 81355138723 scopus 로고    scopus 로고
    • Opioid drug abuse and modulation of immune function: Consequences in the susceptibility to opportunistic infections
    • Roy S, Ninkovic J, Banerjee S, et al. Opioid drug abuse and modulation of immune function: consequences in the susceptibility to opportunistic infections. J Neuroimmune Pharmacol 2011; 6: 442-65.
    • (2011) J Neuroimmune Pharmacol , vol.6 , pp. 442-465
    • Roy, S.1    Ninkovic, J.2    Banerjee, S.3
  • 133
    • 76749157241 scopus 로고    scopus 로고
    • Morphine disrupts interleukin-23 (IL- 23)/IL-17-mediated pulmonary mucosal host defense against Streptococcus pneumoniae infection
    • Ma J, Wang J, Wan J, et al. Morphine disrupts interleukin-23 (IL- 23)/IL-17-mediated pulmonary mucosal host defense against Streptococcus pneumoniae infection. Infect Immun 2010; 78: 830-7.
    • (2010) Infect Immun , vol.78 , pp. 830-837
    • Ma, J.1    Wang, J.2    Wan, J.3
  • 134
    • 77957801542 scopus 로고    scopus 로고
    • Potentiating effect of morphine on oral Salmonella enterica serovar Typhimurium infection is μ-opioid receptor-dependent
    • Breslow JM, Feng P, Meissler JJ, et al. Potentiating effect of morphine on oral Salmonella enterica serovar Typhimurium infection is μ-opioid receptor-dependent. Microb Pathog 2010; 49: 330-5.
    • (2010) Microb Pathog , vol.49 , pp. 330-335
    • Breslow, J.M.1    Feng, P.2    Meissler, J.J.3
  • 135
    • 0027171369 scopus 로고
    • Alterations in rat intestinal transit by morphine promote bacterial translocation
    • Runkel NS, Moody FG, Smith GS, et al. Alterations in rat intestinal transit by morphine promote bacterial translocation. Dig Dis Sci 1993; 38: 1530-6.
    • (1993) Dig Dis Sci , vol.38 , pp. 1530-1536
    • Runkel, N.S.1    Moody, F.G.2    Smith, G.S.3
  • 136
    • 84855829687 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa virulence expression is directly activated by morphine and is capable of causing lethal gut-derived sepsis in mice during chronic morphine administration
    • Babrowski T, Holbrook C, Moss J, et al. Pseudomonas aeruginosa virulence expression is directly activated by morphine and is capable of causing lethal gut-derived sepsis in mice during chronic morphine administration. Ann Surg 2012; 255: 386-93.
    • (2012) Ann Surg , vol.255 , pp. 386-393
    • Babrowski, T.1    Holbrook, C.2    Moss, J.3
  • 137
    • 80053146041 scopus 로고    scopus 로고
    • Leukocyteand platelet-derived microvesicle interactions following in vitro and in vivo activation of toll-like receptor 4 by lipopolysaccharide
    • Xiong J, Miller VM, Hunter LW, Li Y, Jayachandran M. Leukocyteand platelet-derived microvesicle interactions following in vitro and in vivo activation of toll-like receptor 4 by lipopolysaccharide. PLoS One 2011; 6(9):e25504.
    • (2011) PLoS One , vol.6 , Issue.9
    • Xiong, J.1    Miller, V.M.2    Hunter, L.W.3    Li, Y.4    Jayachandran, M.5
  • 138
    • 84879623341 scopus 로고    scopus 로고
    • Morphine induced exacerbation of sepsis is mediated by tempering endotoxin tolerance through modulation of miR-146a
    • Banerjee S, Meng J, Das S, et al. Morphine induced exacerbation of sepsis is mediated by tempering endotoxin tolerance through modulation of miR-146a. Sci Rep 2013; 3: 1977.
    • (2013) Sci Rep , vol.3 , pp. 1977
    • Banerjee, S.1    Meng, J.2    Das, S.3
  • 140
    • 84939968770 scopus 로고    scopus 로고
    • MicroRNAs: Small molecules with big roles in neurodevelopment and diseases
    • pii: S0014- 4886(14)00257-X
    • Sun E, Shi Y. MicroRNAs: Small molecules with big roles in neurodevelopment and diseases. Exp Neurol 2014; pii: S0014- 4886(14)00257-X.
    • (2014) Exp Neurol
    • Sun, E.1    Shi, Y.2
  • 141
  • 142
    • 84891093032 scopus 로고    scopus 로고
    • The involvement of microRNAs in neurodegenerative diseases
    • Maciotta S, Meregalli M, Torrente Y. The involvement of microRNAs in neurodegenerative diseases. Front Cell Neurosci 2013; 7: 265.
    • (2013) Front Cell Neurosci , vol.7 , pp. 265
    • Maciotta, S.1    Meregalli, M.2    Torrente, Y.3
  • 143
    • 84919454311 scopus 로고    scopus 로고
    • Genetic networks lead and follow tumor development: MicroRNA regulation of cell cycle and apoptosis in the p53 pathways
    • Otsuka K, Ochiya T. Genetic networks lead and follow tumor development: microRNA regulation of cell cycle and apoptosis in the p53 pathways. Biomed Res Int 2014; 2014: 749724.
    • (2014) Biomed Res Int , vol.2014
    • Otsuka, K.1    Ochiya, T.2
  • 144
    • 1542537849 scopus 로고    scopus 로고
    • Combining phylogenetic and hidden Markov models in biosequence analysis
    • Siepel A, Haussler D. Combining phylogenetic and hidden Markov models in biosequence analysis. J Comput Biol 2004; 11: 413-28.
    • (2004) J Comput Biol , vol.11 , pp. 413-428
    • Siepel, A.1    Haussler, D.2
  • 145
    • 23744458086 scopus 로고    scopus 로고
    • Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes
    • Siepel A, Bejerano G, Pedersen JS, et al. Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes. Genome Res 2005; 15: 1034-50.
    • (2005) Genome Res , vol.15 , pp. 1034-1050
    • Siepel, A.1    Bejerano, G.2    Pedersen, J.S.3
  • 147
    • 33646017709 scopus 로고    scopus 로고
    • The opioid ligand binding of human mu-opioid receptor is modulated by novel splice variants of the receptor
    • Choi HS, Kim CS, Hwang CK, et al. The opioid ligand binding of human mu-opioid receptor is modulated by novel splice variants of the receptor. Biochem Biophys Res Commun 2006; 19: 1132-40.
    • (2006) Biochem Biophys Res Commun , vol.19 , pp. 1132-1140
    • Choi, H.S.1    Kim, C.S.2    Hwang, C.K.3
  • 148
    • 58749098046 scopus 로고    scopus 로고
    • Isolation and characterization of new exon 11-associated N-terminal splice variants of the human mu opioid receptor gene
    • Xu J, Xu M, Hurd YL, Pasternak GW, and Pan YX. Isolation and characterization of new exon 11-associated N-terminal splice variants of the human mu opioid receptor gene. J Neurochem 2009; 108: 962- 72.
    • (2009) J Neurochem , vol.108 , pp. 962-972
    • Xu, J.1    Xu, M.2    Hurd, Y.L.3    Pasternak, G.W.4    Pan, Y.X.5
  • 149
    • 84881509541 scopus 로고    scopus 로고
    • The N-terminally truncated μ3 and μ3-like opioid receptors are transcribed from a novel promoter upstream of exon 2 in the human OPRM1 gene
    • Andersen A, Baar C, Fladvad T, Laugsand EA, and Skorpen F. The N-terminally truncated μ3 and μ3-like opioid receptors are transcribed from a novel promoter upstream of exon 2 in the human OPRM1 gene. Plos One 2013; 8: e71024.
    • (2013) Plos One , vol.8
    • Andersen, A.1    Baar, C.2    Fladvad, T.3    Laugsand, E.A.4    Skorpen, F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.