Modulations of NeuroD activity contribute to the differential effects of morphine and fentanyl on dendritic spine stability

Journal of Neuroscience

Volumn 30, Issue 24, 2010, Pages 8102-8110

  Zheng, Hui ^a   Zeng, Yan ^a   Chu, Ji ^a   Kam, Angel YuetFang ^a   Loh, Horace H ^a   Law, Ping Yee ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II ALPHA; DOUBLECORTIN; FENTANYL; MESSENGER RNA; MIR 190; MORPHINE; MU OPIATE RECEPTOR; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; NEUROGENIC DIFFERENTIATION FACTOR; NEUROGENIC DIFFERENTIATION FACTOR 4; NOTCH1 RECEPTOR; NUCLEIC ACID BINDING PROTEIN; ROUNDABOUT 1 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL LEVEL; CONTROLLED STUDY; DENDRITIC SPINE; HIPPOCAMPUS; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SAMPLE;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BENZYLAMINES; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CELLS, CULTURED; DENDRITIC SPINES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FENTANYL; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; HIPPOCAMPUS; MICROTUBULE-ASSOCIATED PROTEINS; MORPHINE; NARCOTICS; NERVE TISSUE PROTEINS; NEURONS; NEUROPEPTIDES; PHOSPHORYLATION; RATS; RECEPTOR, NOTCH1; RECEPTORS, IMMUNOLOGIC; RECEPTORS, OPIOID, MU; RNA, MESSENGER; SULFONAMIDES; TIME FACTORS; TRANSDUCTION, GENETIC;

EID: 77953773592     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.6069-09.2010     Document Type: Article

References (35)

1. Bao G, Kang L, Li H, Li Y, Pu L, Xia P, Ma L, Pei G (2007) Morphine and heroin differentially modulate in vivo hippocampal LTP in opiate-dependent rat. Neuropsychopharmacology 32:1738-1749.
2. Breunig JJ, Silbereis J, Vaccarino FM, Sestan N, Rakic P (2007) Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus. Proc Natl Acad Sci U S A 104:20558-20563.
3. Chae JH, Stein GH, Lee JE (2004) NeuroD: the predicted and the surprising. Mol Cells 18:271-288.
4. Chen Y, Mestek A, Liu J, Yu L (1993) Molecular cloning of a rat kappa opioid receptor reveals sequence similarities to the mu and delta opioid receptors. Biochem J 295:625-628. (Pubitemid 23323479)
5. Cho JH, Tsai MJ (2004) The role of BETA2/NeuroD1 in the development of the nervous system. Mol Neurobiol 30:35-47. (Pubitemid 41271219)
6. Colbran RJ, Brown AM (2004) Calcium/calmodulin-dependent protein kinase II and synaptic plasticity. Curr Opin Neurobiol 14:318-327.
7. Diana M, Spiga S, Acquas E (2006) Persistent and reversible morphine withdrawal-induced morphological changes in the nucleus accumbens. Ann N Y Acad Sci 1074:446-457.
8. Duttaroy A, Yoburn BC (1995) The effect of intrinsic efficacy on opioid tolerance. Anesthesiology 82:1226-1236.
9. Eisch AJ, Barrot M, Schad CA, Self DW, Nestler EJ (2000) Opiates inhibit neurogenesis in the adult rat hippocampus. Proc Natl Acad Sci U S A 97:7579-7584.
10. Gáborik Z, Szaszák M, Szidonya L, Balla B, Paku S, Catt KJ, Clark AJ, Hunyady L (2001) Beta-arrestin- and dynamin-dependent endocytosis of the AT1 angiotensin receptor. Mol Pharmacol 59:239-247.
11. Gaudillière B, Konishi Y, de la Iglesia N, Yao G, Bonni A (2004) A CaMKII-NeuroD signaling pathway specifies dendritic morphogenesis. Neuron 41:229-241.
12. Kayser MS, Nolt MJ, Dalva MB (2008) EphB receptors couple dendritic filopodia motility to synapse formation. Neuron 59:56-69.
13. Liao D, Lin H, Law PY, Loh HH (2005) Mu-opioid receptors modulate the stability of dendritic spines. Proc Natl Acad Sci U S A 102:1725-1730.
14. Liao D, Grigoriants OO, Loh HH, Law PY (2007a) Agonist-dependent postsynaptic effects of opioids on miniature excitatory postsynaptic currents in cultured hippocampal neurons. J Neurophysiol 97:1485-1494.
15. Liao D, Grigoriants OO, Wang W, Wiens K, Loh HH, Law PY (2007b) Distinct effects of individual opioids on the morphology of spines depend upon the internalization of mu opioid receptors. Mol Cell Neurosci 35:456-469.
16. Lin H, Higgins P, Loh HH, Law PY, Liao D (2009) Bidirectional effects of fentanyl on dendritic spines and AMPA receptors depend upon the internalization of mu opioid receptors. Neuropsychopharmacology 34:2097-2111.
17. Lou L, Zhou T, Wang P, Pei G (1999) Modulation of Ca2+/calmodulin- dependent protein kinase II activity by acute and chronic morphine administration in rat hippocampus: differential regulation of alpha and beta isoforms. Mol Pharmacol 55:557-563. (Pubitemid 29128114)
18. Ma L, Pei G (2007) Beta-arrestin signaling and regulation of transcription. J Cell Sci 120:213-218.
19. Mei B, Niu L, Cao B, Huang D, Zhou Y (2009) Prenatal morphine exposure alters the layer II/III pyramidal neurons morphology in lateral secondary visual cortex of juvenile rats. Synapse 63:1154-1161.
20. Pratt KG, Watt AJ, Griffith LC, Nelson SB, Turrigiano GG (2003) Activity-dependent remodeling of presynaptic inputs by postsynaptic expression of activated CaMKII. Neuron 39:269-281.
21. Pu L, Bao GB, Xu NJ, Ma L, Pei G (2002) Hippocampal long-term potentiation is reduced by chronic opiate treatment and can be restored by reexposure to opiates. J Neurosci 22:1914-1921. (Pubitemid 35386310)
22. Ricalde AA, Hammer RP Jr (1990) Perinatal opiate treatment delays growth of cortical dendrites. Neurosci Lett 115:137-143.
23. Robinson TE, Gorny G, Savage VR, Kolb B (2002) Widespread but regionally specific effects of experimenter- versus self-administered morphine on dendritic spines in the nucleus accumbens, hippocampus, and neocortex of adult rats. Synapse 46:271-279.
24. Schafer DA (2004) Regulating actin dynamics at membranes: a focus on dynamin. Traffic 5:463-469.
25. Seo S, Lim JW, Yellajoshyula D, Chang LW, Kroll KL (2007) Neurogenin and NeuroD direct transcriptional targets and their regulatory enhancers. EMBO J 26:5093-5108.
26. Sumi M, Kiuchi K, Ishikawa T, Ishii A, Hagiwara M, Nagatsu T, Hidaka H (1991) The newly synthesized selective Ca2+/calmodulin dependent protein kinase II inhibitor KN-93 reduces dopamine contents in PC12h cells. Biochem Biophys Res Commun 181:968-975.
27. Vaillant AR, Zanassi P, Walsh GS, Aumont A, Alonso A, Miller FD (2002) Signaling mechanisms underlying reversible, activity-dependent dendrite formation. Neuron 34:985-998.
28. Violin JD, Lefkowitz RJ (2007) Beta-arrestin-biased ligands at seven-transmembrane receptors. Trends Pharmacol Sci 28:416-422.
29. von Bohlen und Halbach O (2007) Immunohistological markers for staging neurogenesis in adult hippocampus. Cell Tissue Res 329:409-420.
30. Wayman GA, Lee YS, Tokumitsu H, Silva A, Soderling TR (2008) Calmodulin-kinases: modulators of neuronal development and plasticity. Neuron 59:914-931.
31. Zhao H, Loh HH, Law PY (2006) Adenylyl cyclase superactivation induced by long-term treatment with opioid agonist is dependent on receptor localized within lipid rafts and is independent of receptor internalization. Mol Pharmacol 69:1421-1432.
32. Zheng H, Loh HH, Law PY (2008a) Beta-arrestin-dependent mu-opioid receptor-activated extracellular signal-regulated kinases (ERKs) translocate to nucleus in contrast to G protein-dependent ERK activation. Mol Pharmacol 73:178-190.
33. Zheng H, Chu J, Qiu Y, Loh HH, Law PY (2008b) Agonist-selective signaling is determined by the receptor location within the membrane domains. Proc Natl Acad Sci U S A 105:9421-9426.
34. Zheng H, Loh HH, Law PY (2010a) Agonist-selective signaling of G protein-coupled receptor: mechanisms and implications. IUBMB Life 62:112-119.
35. Zheng H, Zeng Y, Zhang X, Chu J, Loh HH, Law PY (2010b) Mu-opioid receptor agonists differentially regulate the expression of miR-190 and NeuroD. Mol Pharmacol 77:102-109.