Stabilization of the μ-opioid receptor by truncated single transmembrane splice variants through a chaperone-like action

Journal of Biological Chemistry

Volumn 288, Issue 29, 2013, Pages 21211-21227

  Xu, Jin ^a   Xu, Ming ^a   Brown, Taylor ^a   Rossi, Grace C ^b   Hurd, Yasmin L ^c   Inturrisi, Charles E ^d   Pasternak, Gavril W ^a,d   Pan, Ying Xian ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b LONG ISLAND UNIVERSITY   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNATIVE SPLICING; OPIOID RECEPTORS; SPLICE VARIANTS; TRANSMEMBRANES;

BIOCHEMISTRY;

BIOLOGY;

G PROTEIN COUPLED RECEPTOR; MEMBRANE PROTEIN; MU 1 OPIATE RECEPTOR; MU OPIATE RECEPTOR; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANTISENSE VECTOR; ARTICLE; CONTROLLED STUDY; DIMERIZATION; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM ASSOCIATED DEGRADATION; GENE; GENETIC VARIABILITY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VIVO STUDY; MALE; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPRM1 GENE; PLASMID; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; RNA SPLICING; UBIQUITINATION;

ALTERNATIVE SPLICING; ANALGESIA; ANTISENSE OLIGODEOXYNUCLEOTIDE; DIMERIZATION; G PROTEIN-COUPLED RECEPTORS (GPCR); MOLECULAR CHAPERONE; MORPHINE; OPIATE OPIOID; RECEPTOR REGULATION;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BREFELDIN A; CELL MEMBRANE; CLONING, MOLECULAR; DNA, COMPLEMENTARY; ENDOPLASMIC RETICULUM; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; GENE EXPRESSION PROFILING; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; MICE; MOLECULAR CHAPERONES; MORPHINE; OLIGONUCLEOTIDES, ANTISENSE; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, OPIOID, MU; RNA, MESSENGER; UBIQUITINATION;

EID: 84880533674     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.458687     Document Type: Article

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