Pseudomonas aeruginosa virulence expression is directly activated by morphine and is capable of causing lethal gut-derived sepsis in mice during chronic morphine administration

Annals of Surgery

Volumn 255, Issue 2, 2012, Pages 386-393

  Babrowski, Trissa ^a   Holbrook, Christopher ^a   Moss, Jonathan ^b   Gottlieb, Lawrence ^b   Valuckaite, Vesta ^a   Zaborin, Alexander ^a   Poroyko, Valeriy ^a   Liu, Donald C ^a   Zaborina, Olga ^a   Alverdy, John C ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

17 METHYLNALTREXONE; INTERLEUKIN 10; INTERLEUKIN 6; LECTIN; MORPHINE; PLACEBO; PSEUDOMONAS AERUGINOSA I LECTIN; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CECUM; CHEMOTAXIS; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; CYTOKINE RESPONSE; DOSE RESPONSE; DRUG EXPOSURE; GRAM NEGATIVE SEPSIS; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; INOCULATION; INTESTINE EPITHELIUM; INTESTINE MUCOSA PERMEABILITY; LETHALITY; MALE; MORTALITY; MOUSE; MUCUS SECRETION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTION;

ADHESINS, BACTERIAL; ANALGESICS, OPIOID; ANIMALS; CHEMOTAXIS; INTESTINAL MUCOSA; LECTINS; MICE; MORPHINE; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; RANDOM ALLOCATION; REAL-TIME POLYMERASE CHAIN REACTION; SEPSIS; VIRULENCE; VIRULENCE FACTORS;

EID: 84855829687     PISSN: 00034932     EISSN: 15281140     Source Type: Journal    
DOI: 10.1097/SLA.0b013e3182331870     Document Type: Article

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