Unidirectional cross-activation of GRPR by MOR1D uncouples itch and analgesia induced by opioids

Cell

Volumn 147, Issue 2, 2011, Pages 447-458

  Liu, Xian Yu ^a,b   Liu, Zhong Chun ^a,b   Sun, Yan Gang ^a   Ross, Michael ^a   Kim, Seungil ^a,b   Tsai, Feng Fang ^a   Li, Qi Fang ^a,b   Jeffry, Joseph ^a,b   Kim, Ji Young ^b   Loh, Horace H ^c   Chen, Zhou Feng ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; FENTANYL; GASTRIN RELEASING PEPTIDE RECEPTOR; HETERODIMER; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR 3; MORPHINE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR 1D; OPIATE; PHOSPHOLIPASE C BETA3; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DIMERIZATION; DRUG DOSE INCREASE; DRUG EFFECT; HUMAN; HUMAN CELL; INTERNALIZATION; MOLECULAR DYNAMICS; MORPHINE TOLERANCE; MOUSE; NOCICEPTION; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PRURITUS; SCRATCHING; SIGNAL TRANSDUCTION; SPINAL CORD; SPINAL CORD DORSAL HORN;

EID: 80054709876     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2011.08.043     Document Type: Article

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